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FY2024 NIH awards · Principal investigators

Biochemistry at UT Southwestern Medical Center

Dallas, TX

Funding
$27M
$26,990,695
Awards
79
FY2024 NIH awards in Biochemistry
Principal investigators
61
54 lead a grant here, 7 co-investigators
Department rank
#4
of 139 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Biochemistry row of the UT Southwestern Medical Center page.

Leads a grant in this department

54 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Margaret A. Phillips

    Leads 4 awards · $1,967,788

    • 5R01AI103947-12Department: NIH department code
      Lead Optimization of DHODH Inhibitors for Malaria
      $766,060
      award amount
    • 5R01AI155784-04Department: NIH department code
      Optimization of novel phenotypic screening hits for treatment of Malaria

      Principal investigators: Margaret A. Phillips (contact PI), Joseph M Ready

      $737,236
      award amount
    • 5R01AI034432-29Department: NIH department code
      POLYAMINE AND TRYPANOTHIONE METABOLISM IN TRYPANOSOMA BRUCEI
      $445,837
      award amount
    • 3R01AI155784-04S1Department: NIH department code
      Optimization of novel phenotypic screening hits for treatment of Malaria

      Principal investigators: Margaret A. Phillips (contact PI), Joseph M Ready

      $18,655
      award amount
  2. Joseph M Ready

    Leads 3 awards · $1,488,393

    • 5RM1GM142002-04Department: NIH department code
      Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and Regeneration

      Principal investigators: Joseph M Ready (contact PI), Andrew A Pieper, Sanford D. Markowitz

      $1,354,462
      award amount
    • 3RM1GM142002-04S1Department: NIH department code
      Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and Regeneration

      Principal investigators: Joseph M Ready (contact PI), Andrew A Pieper, Sanford D. Markowitz

      $94,538
      award amount
    • 3RM1GM142002-03S1Department: NIH department code
      Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and Regeneration

      Principal investigators: Joseph M Ready (contact PI), Andrew A Pieper, Derek James Taylor, Sanford D. Markowitz

      $39,393
      award amount

    Also a principal investigator on 5R01AI155784-04, led by Margaret A. Phillips; 3R01AI155784-04S1, led by Margaret A. Phillips.

  3. Michael Buszczak

    Leads 3 awards · $1,173,652

    • 5R35GM144043-03Department: NIH department code
      Genetic Dissection of Germ Cell Differentiation and Function
      $488,952
      award amount
    • 1UG3CA290312-01Department: NIH department code
      Developing ribosome biogenesis inhibitors for the prevention of cancer

      Principal investigators: Michael Buszczak (contact PI), Vincent Scott Tagliabracci

      $348,500
      award amount
    • 5R01AG079513-03Department: NIH department code
      Characterization of how mRNA translation influences reproductive aging
      $336,200
      award amount
  4. Eric N Olson

    Leads 2 awards · $1,008,705

    • 5R01HL157281-03Department: NIH department code
      Transcriptional Control of Neonatal Heart Regeneration

      Principal investigators: Eric N Olson (contact PI), Rhonda Bassel-Duby

      $553,736
      award amount
    • 5R01AR080676-02Department: NIH department code
      The role of nuclear envelope protein NET39 in skeletal muscle function and diseases

      Principal investigators: Eric N Olson (contact PI), Ning Liu

      $454,969
      award amount
  5. Lu Sun

    Leads 1 award · $984,000

    • 4DP2MH129988-02Department: NIH department code
      Molecular and genetic decoding of neuron-glial interactions
      $984,000
      award amount
  6. Lorena Saelices Gomez

    Leads 1 award · $964,800

    • 4DP2HL163810-02Department: NIH department code
      Closing the gap between structural biology and translational science for amyloid diseases
      $964,800
      award amount
  7. Jose Rizorey

    Leads 1 award · $938,500

    • 5R35NS097333-08Department: NIH department code
      Mechanisms of neurotransmitter release and its regulation
      $938,500
      award amount
  8. Jin Jiang

    Leads 1 award · $888,257

    • 5R35GM118063-09Department: NIH department code
      Cell signaling in development and regeneration
      $888,257
      award amount
  9. Chun-Li Zhang

    Leads 2 awards · $876,629

    • 5R01NS127375-03Department: NIH department code
      PAX6-induced adult neurogenesis
      $466,072
      award amount
    • 5R01NS117065-05Department: NIH department code
      In Vivo Reprogramming of NG2 Glia for Neurogenesis
      $410,557
      award amount
  10. Yunsun Nam

    Leads 3 awards · $851,252

    • 5R01CA258589-03Department: NIH department code
      Small molecules to target the RNA methyltransferase complex METTL3/METTL14
      $382,200
      award amount
    • 5R01GM122960-08Department: NIH department code
      Mechanisms of Microprocessor Function and Regulation
      $354,750
      award amount
    • 3R01GM122960-08S1Department: NIH department code
      Mechanisms of Microprocessor Function and Regulation
      $114,302
      award amount
  11. Sarah H Shahmoradian

    Leads 2 awards · $821,468

    • 5R01NS133517-02Department: NIH department code
      Determine the neurotoxicity of RNA metabolism dysfunction caused by cytoplasmic TDP-43 aggregates
      $616,468
      award amount
    • 5R21AG080497-02Department: NIH department code
      Cellular Anatomy of Tau Seeding
      $205,000
      award amount
  12. Jennifer J Kohler

    Leads 2 awards · $771,698

    • 5R35GM145599-03Department: NIH department code
      Function and regulation of epithelial glycosylation
      $525,698
      award amount
    • 1R21AI183574-01Department: NIH department code
      Discovery of pertussis toxin receptors
      $246,000
      award amount
  13. Peter Mahan Douglas

    Leads 3 awards · $762,762

    • 1R01GM153859-01Department: NIH department code
      Multimodal regulation of intracellular lipid surveillance
      $376,962
      award amount
    • 5R01AG076529-03Department: NIH department code
      Lipid sensing through G protein geranylgeranylation
      $335,900
      award amount
    • 1R13AG085955-01Department: NIH department code
      C. elegans Metabolism, Aging, Pathogenesis, Stress and Small RNAs Symposium
      $49,900
      award amount
  14. Elizabeth H Chen

    Leads 2 awards · $759,976

    • 5R35GM136316-05Department: NIH department code
      Decoding the mechanisms of cell-cell fusion
      $410,000
      award amount
    • 5R01AR075005-05Department: NIH department code
      Investigating mechanisms of vertebrate myoblast fusion using zebrafish as a model
      $349,976
      award amount
  15. Xiaochen Bai

    Leads 2 awards · $758,919

    • 5R01GM143158-04Department: NIH department code
      Structural insights into the unique activation mechanisms of receptor tyrosine kinases
      $406,319
      award amount
    • 5R01GM136976-05Department: NIH department code
      Structural and Functional Analyses of the Full-length Insulin Receptor (IR) and Type 1 Insulin-like Growth Factor Receptor (IGF1R) in the Liganded Active State
      $352,600
      award amount
  16. Kendra King Frederick

    Leads 3 awards · $734,543

    • 1R01NS134921-01Department: NIH department code
      High sensitivity NMR for structure determination of neurodegenerative disease associated protein aggregates in native contexts
      $410,000
      award amount
    • 1R21NS136951-01Department: NIH department code
      Determining the influence of cellular environments on a-synuclein fibril conformations
      $244,203
      award amount
    • 3R01NS134921-01S1Department: NIH department code
      High sensitivity NMR for structure determination of neurodegenerative disease associated protein aggregates in native contexts
      $80,340
      award amount
  17. Jun Wu

    Leads 2 awards · $689,642

    • 5R01HD103627-03Department: NIH department code
      Dissect the mechanisms underlying interspecies pluripotent stem cell competition
      $349,074
      award amount
    • 5R01GM138565-04Department: NIH department code
      Dissect formative pluripotency using cultured pluripotent stem cells
      $340,568
      award amount
  18. Chuo Chen

    Leads 1 award · $616,283

    • 5R01CA269377-02Department: NIH department code
      Therapeutic targeting of Wnt signaling in cancer
      $616,283
      award amount
  19. Daniel Luke Kober

    Leads 2 awards · $593,400

    • 1R01GM155152-01Department: NIH department code
      Structural and mechanistic basis for the maturation of site-one protease in the secretory pathway
      $344,400
      award amount
    • 5R00GM141261-03Department: NIH department code
      The mechanistic basis for targeted protein degradation in lipid metabolism
      $249,000
      award amount
  20. Steven L McKnight

    Leads 1 award · $533,000

    • 2R35GM130358-06Department: NIH department code
      A solid state conceptualization of information transfer from gene to message to protein
      $533,000
      award amount
  21. Jenna L Jewell

    Leads 1 award · $492,000

    • 5R35GM149351-02Department: NIH department code
      mTORC1 Regulation by Upstream Stimuli
      $492,000
      award amount
  22. Joshua T Mendell

    Leads 1 award · $465,092

    • 5R01CA282036-02Department: NIH department code
      The role of long noncoding RNA CRNDE in normal physiology and cancer
      $465,092
      award amount
  23. Kathryn Ann O'Donnell

    Leads 1 award · $452,600

    • 5R01CA273585-02Department: NIH department code
      The role of translation initiation factor eIF5B in lung cancer pathogenesis
      $452,600
      award amount
  24. Tian Qin

    Leads 2 awards · $437,317

    • 5R01GM141088-04Department: NIH department code
      Development of Sulfur-Based Reactions with Translational Applications
      $324,060
      award amount
    • 3R01GM141088-04S1Department: NIH department code
      Development of Sulfur-Based Reactions with Translational Applications
      $113,257
      award amount
  25. Zbyszek Otwinowski

    Leads 1 award · $435,502

    • 5R35GM145365-03Department: NIH department code
      From complex data to complex structures: new methods for structural biology
      $435,502
      award amount
  26. Khuloud Jaqaman

    Leads 1 award · $426,095

    • 5R35GM119619-09Department: NIH department code
      Mechanisms and Functional Consequences of Signaling Protein Organization at Membranes
      $426,095
      award amount
  27. Glen Liszczak

    Leads 1 award · $410,000

    • 5R35GM147140-03Department: NIH department code
      Regulation and function of site-specific protein poly-ADP-ribosylation
      $410,000
      award amount
  28. Weiwei Wang

    Leads 1 award · $410,000

    • 5R35GM146860-03Department: NIH department code
      Understanding higher-order glycine receptor assemblies in neurotransmission
      $410,000
      award amount
  29. Daniel Rosenbaum

    Leads 1 award · $406,794

    • 5R35GM136387-05Department: NIH department code
      Membrane signaling protein modulation by lipids and drugs
      $406,794
      award amount
  30. Benjamin P Tu

    Leads 1 award · $402,168

    • 5R35GM136370-05Department: NIH department code
      Metabolic signals regulating cell growth versus survival
      $402,168
      award amount
  31. Zhijian J Chen

    Leads 1 award · $374,366

    • 3OT2CA278683-01S2Department: NIH department code
      eDyNAmiC-TEXASSW
      $374,366
      award amount
  32. Kim Orth

    Leads 1 award · $369,000

    • 5R35GM134945-05Department: NIH department code
      Biochemistry, biology and diversity of Fic domains
      $369,000
      award amount
  33. Michael K Rosen

    Leads 1 award · $369,000

    • 5R35GM141736-04Department: NIH department code
      Cell Organization Through Phase Separation: Mechanisms, Functions and Disease
      $369,000
      award amount
  34. Steven A. Kliewer

    Leads 1 award · $369,000

    • 5R01AA028473-05Department: NIH department code
      Coordinate Regulation of an Alcohol Protective Response by the Liver-derived Hormone FGF21

      Principal investigators: Steven A. Kliewer (contact PI), David J Mangelsdorf

      $369,000
      award amount
  35. Konstantin Doubrovinski

    Leads 1 award · $354,732

    • 2R01GM134207-06Department: NIH department code
      Physical aspects of Drosophila Gastrulation
      $354,732
      award amount
  36. Richard Dustin Schaeffer

    Leads 1 award · $344,400

    • 5R01GM147367-02Department: NIH department code
      ECOD: Large scale classification of predicted and experimental protein structures
      $344,400
      award amount
  37. Jan Peter Erzberger

    Leads 1 award · $340,172

    • 5R01GM135617-05Department: NIH department code
      Integrated studies of DEAD-box ATPase function during large ribosomal subunit maturation
      $340,172
      award amount
  38. Uttam Krishan Tambar

    Leads 1 award · $338,632

    • 5R01GM102604-13Department: NIH department code
      Stereoselective Photochemistry for the Synthesis of Bioactive Molecules
      $338,632
      award amount
  39. Matthew W. Parker

    Leads 1 award · $337,949

    • 1R01GM155100-01Department: NIH department code
      Defining the modular architecture of protein intrinsically disordered regions for a predictive understanding of biological function
      $337,949
      award amount
  40. Myles Warwick Smith

    Leads 1 award · $328,000

    • 1R35GM155273-01Department: NIH department code
      Expanding Access to Molecular Complexity through Natural Product Synthesis
      $328,000
      award amount
  41. Megan L Norris

    Leads 1 award · $132,390

    • 5K99HD109457-02Department: NIH department code
      Regulation and function of subcellular RNA localization in neural crest cells and their derivatives
      $132,390
      award amount
  42. Stanislaw Marek Deja

    Leads 1 award · $103,385

    • 5K01DK133630-03Department: NIH department code
      Sympathetic Control of Liver Metabolism in Exercise and Obesity
      $103,385
      award amount
  43. Peiheng Gan

    Leads 1 award · $100,480

    • 1K99HL171888-01A1Department: NIH department code
      RBPMS, a novel RNA splicing regulator of cardiac function and disease
      $100,480
      award amount
  44. Xurde Menendez Caravia

    Leads 1 award · $100,480

    • 1K99HL171887-01A1Department: NIH department code
      Understanding the roles of nuclear envelope proteins and DNA damage in cardiomyopathy
      $100,480
      award amount
  45. Matthieu Dos Santos

    Leads 1 award · $95,080

    • 1K99AR084549-01Department: NIH department code
      Characterization of Maf function in muscle atrophy
      $95,080
      award amount
  46. Benjamin Jacob Mayro

    Leads 1 award · $92,113

    • 5K00CA264162-04Department: NIH department code
      Understanding the impact that tumor representative oxygen tension has on phosphotyrosine-dependent signaling networks in solid tumors
      $92,113
      award amount
  47. Shayna Thomas-Jardin

    Leads 1 award · $76,756

    • 5F32CA274982-02Department: NIH department code
      Immune Checkpoint Regulation by the Integrated Stress Response Pathway in Lung Ca
      $76,756
      award amount
  48. Chidinma Nnadi

    Leads 1 award · $45,574

    • 1F31GM154424-01Department: NIH department code
      Post-translational regulation of NORAD-induced Pumilio phase separation
      $45,574
      award amount
  49. Mary Wilton Newton Burns

    Leads 1 award · $40,242

    • 5F30DK136209-02Department: NIH department code
      The Impact of B3GNT7 on Properties of Intestinal Mucus and the Gut Microbiome
      $40,242
      award amount
  50. Peter Luo

    Leads 1 award · $40,242

    • 5F30DK137405-02Department: NIH department code
      The role and regulation of pericytes in remodeling the periarterial niche during nephrogenesis
      $40,242
      award amount
  51. Blake Christopher Williams

    Leads 1 award · $40,127

    • 1F31HL176187-01Department: NIH department code
      Structural and biophysical investigation of Scap regulation by cholesterol
      $40,127
      award amount
  52. Michael R McConville

    Leads 1 award · $40,048

    • 5F30HL167629-02Department: NIH department code
      Unexpected mechanism underlying mislocalization of thrombocytopenia-associated ETV6 point mutation
      $40,048
      award amount
  53. Ping Mu

    Leads 4 awards · $20,016

    • 1R01CA288820-01Department: NIH department code
      Deciphering the Impact of ZNF397-deficiency in Promoting TET2-driven Epigenetic Rewiring, Lineage Plasticity, and Therapy Resistance in Prostate Cancer
      $8,266
      award amount
    • 1R01CA292949-01Department: NIH department code
      Unveiling the Role of UBE2J1 as the E2 Ubiquitin Conjugating Enzyme in Androgen Receptor Degradation
      $8,200
      award amount
    • 3R37CA258730-04S1Department: NIH department code
      Elucidating the Molecular Role of SYNCRIP in Prostate Cancer and AR Targeted Therapy Resistance
      $3,549
      award amount
    • 5R37CA258730-04Department: NIH department code
      Elucidating the Molecular Role of SYNCRIP in Prostate Cancer and AR Targeted Therapy Resistance
      $1
      award amount
  54. Karla Gabriela Cano Hernandez

    Leads 1 award · $17,276

    • 5F31CA271675-03Department: NIH department code
      The Molecular function of ecto 5' nucleotidase in fusion-negative rhabdomyosarcoma
      $17,276
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

  • Andrew A Pieper

    Co-investigator on 5RM1GM142002-04, led by Joseph M Ready; 3RM1GM142002-04S1, led by Joseph M Ready; 3RM1GM142002-03S1, led by Joseph M Ready

    Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

  • Sanford D. Markowitz

    Co-investigator on 5RM1GM142002-04, led by Joseph M Ready; 3RM1GM142002-04S1, led by Joseph M Ready; 3RM1GM142002-03S1, led by Joseph M Ready

    From the FY2024 awards this person leads

  • Rhonda Bassel-Duby

    Co-investigator on 5R01HL157281-03, led by Eric N Olson

    Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

  • Ning Liu

    Co-investigator on 5R01AR080676-02, led by Eric N Olson

    Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

  • David J Mangelsdorf

    Co-investigator on 5R01AA028473-05, led by Steven A. Kliewer

    Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

  • Vincent Scott Tagliabracci

    Co-investigator on 1UG3CA290312-01, led by Michael Buszczak

    From the FY2024 awards this person leads

  • Derek James Taylor

    Co-investigator on 3RM1GM142002-03S1, led by Joseph M Ready

    From the FY2024 awards this person leads