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NIH funding notice PA-15-269

PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Closed on April 5, 2016.

Posted
June 4, 2015
Close date
April 5, 2016
Activity codes
R43, R44
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP, CSELS, NCHS, NCIPC, NIOSH, CBER, CDER, CFSAN, CDRH, CVM, CPI, OPD, OPRE

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-14-071 PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  2. 2 steps back: PA-13-234 Reissue PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  3. 3 steps back: PA-13-088 PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  4. 4 steps back: PA-12-088 PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  5. 5 steps back: PA-11-096 PHS 2011-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  6. 6 steps back: PA-10-050 PHS 2010-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  7. 7 steps back: PA-09-080 PHS 2009-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Replaced by PA-16-302.

Who won it before

2,074 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $722,483,375 in first-year total cost, median $224,999.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-G (12)]132
  2. Special Emphasis Panel[ZRG1 ETTN-M (11)]106
  3. Special Emphasis Panel[ZRG1 SBIB-T (10)]98
  4. Special Emphasis Panel[ZRG1 RPHB-C (10)]87
  5. Special Emphasis Panel[ZRG1 IDM-V (12)]68

Most frequent institutions

  1. PANORAMA RESEARCH, INC.19
  2. PROGENRA, INC.15
  3. AFFINERGY, LLC14
  4. PHYSICAL SCIENCES, INC12
  5. 3-C INSTITUTE FOR SOCIAL DEVELOPMENT10
Competing awards under PA-15-269 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2017Enzyme replacement therapy for GM1 gangliosidosis lysosomal rare disease2R44NS084565-02ACOSTA, WALTERCRAMER, CAROLE L.D'AZZO, ALESSANDRARADIN, DAVIDBIOSTRATEGIES, LC, AR$1,366,586ZRG1
2017TempO-Seq: A Multiplexed Gene Expression Profiling Platform2R44HG007339-03YEAKLEY, JOANNE MULLIGANBIOSPYDER TECHNOLOGIES, INC., CA$1,258,482ZRG1
2017Safety and Efficacy Testing of FX101 in an SIV/NHP Model2R44MH096663-03A1BOLTON, DIANE L.KAY, HEIDI ARAPPAPORT, JAYJERICHO SCIENCES, LLC, VA$1,154,643ZRG1
2017Production Technology for Recombinant Intravenous Immunoglobulin2R44AI115892-02A1JOHNSON, DAVID SCOTTGIGAGEN, INC., CA$1,000,000ZRG1
2017Advanced PML antiviral2R44AI103982-04WERNER, MILTON H.INHIBIKASE THERAPEUTICS, GA$1,000,000ZRG1
2017A Phase III Trial to Validate HP 129Xe MRI as a Functional Pulmonary Biomarker in Pediatric Lung Disease2R44HL123299-02A1EMAMI, KIARASHPOLAREAN, INC., NC$999,713ZRG1
2017Selective Depletion of Insulin-Specific B cells to Prevent Type 1 Diabetes2R44DK107099-02ZION, TODD CAKSTON BIOSCIENCES CORPORATION, MA$998,123ZRG1
2017TempO-Seq for Preserved Tissues in Toxicity Testing Phase II2R44ES024107-02SELIGMANN, BRUCE E.BIOSPYDER TECHNOLOGIES, INC., CA$979,864ZRG1
2017Analytical Methods for Automated Quality Control of Cancer PET Imaging Tracer - [F-18]FDG2R44CA192499-02ELIZAROV, ARKADIJTRACE-ABILITY, INC., CA$859,830ZRG1
2017Product Development for Bromodomain Networks2R44TR001268-02MA, HAICHINGREACTION BIOLOGY CORPORATION, PA$848,800ZRG1
2017Automated Isolation of Single Cells Using High-Resolution and Subcellular Imaging2R44GM119888-02A1GEBHART, STEVEN CHARLESCELL MICROSYSTEMS, INC., NC$818,501ZRG1
2017High Energy Density, Long Life, Betavoltaic Power Cells for Pacemakers and other Implantable Devices2R44HL127706-02THOMAS, CHRISWIDETRONIX, INC., NY$773,585ZRG1
2017HOME: Monitoring Balance and Gait with the Home Objective Mobility Exam2R44AG044863-03EL-GOHARY, MAHMOUDHORAK, FAY BAHLINGAPDM, INC., OR$767,705ZRG1
2017Ubiquitin pathway inhibitors for treatment of asthma2R44AI109980-02A1SURESH, KUMARPROGENRA, INC., PA$757,044ZRG1
2017Large Scale Synthesis of the Next Generation Synthetic Saponin Adjuvant TiterQuil2R44AI114030-02LIVINGSTON, PHILIP O.ADJUVANCE TECHNOLOGIES, INC., NY$756,567ZRG1
2017PicoSep - A Microfluidic Platform for Single Molecule DNA and RNA Sizing2R44GM103356-03A1LIU, KELVINWANG, TZA-HUEI JEFFCIRCULOMICS, INC., MD$746,273ZRG1
2017Cell Line Panel Profiling for Discovery of Multiple Myeloma Therapeutics2R44CA183470-02KRUTZIK, PETERPRIMITY, INC., CA$745,194ZRG1
2017Development of an improved, low-cost polio vaccine (Ir-IPV)2R44AI120260-02TOBIN, GREGORY JOHNBIOLOGICAL MIMETICS, INC., MD$743,104ZRG1
2017Tools for Faster and Cheaper Delivery of Integrated Registries2R44MH099826-03A1ROZENBLIT, LEONPROMETHEUS RESEARCH, LLC, CT$742,523ZRG1
2017Competitive Equilibrium-based Displacement of Bisphosphonates as Novel Therapeutic Approach for BRONJ2R44DE025524-02EBETINO, FRANK H.BIOVINC, LLC, CA$740,777ZRG1
2017High-throughput Identification of Membrane Protein MAbs2R44GM113556-02A1DORANZ, BENJAMIN JINTEGRAL MOLECULAR, PA$686,432ZRG1
2017CRISPR Genome-Wide sgRNA Library Screening Platform2R44HG008578-02TEDESCO, DONATOCELLECTA, INC., CA$651,831ZRG1
2017A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming2R44EY021079-05ADAMS, RICHARD J.BARRON ASSOCIATES, INC., VA$627,545ZRG1
2017Development of high-throughput cardiotoxicity and hepatotoxicity assays with magnetic 3D bioprinting2R44ES024644-02A1TSENG, HUBERTNANO3D BIOSCIENCES, INC., TX$623,123ZRG1
2017Optimization of Supercritical Carbon Dioxide Based Virus Inactivation, Characterized by Protein Damage and Maintenance of Epitope Integrity in Vaccine Sterilization2R44AI120282-02FEY, JULIENNOVASTERILIS, INC., NY$608,082ZRG1
2017Localized Delivery of Sirolimus to Hemodialysis Vascular Access Grafts1R44AG059279-01A1ROY-CHAUDHURY, PRABIRSHEBUSKI, RONALD J.CYLERUS, INC., FL$603,715ZRG1
2017Phase II: Feasibility assessment of a novel tool for mosquito vector control: Auto-Dissemination Augmented by Males (ADAM)2R44AI112048-02KELLY, PATRICKMOSQUITOMATE, INC., KY$597,201ZRG1
2017A device for monitoring heart failure patients2R44HL099053-02A1SANDLER, RICHARD HAROLDBIOMEDICAL ACOUSTICS RESEARCH COMPANY, FL$570,451ZRG1
2017Next Generation Western for high-throughput and high-content protein analysis2R44GM112289-03FURTAW, MICHAEL DLI-COR BIOSCIENCES, INC., NE$548,838ZRG1
2017On-line Measurement of the Capacity of Airborne Particulate Matter to Generate Reactive Oxygen Species2R44ES025468-02EIGUREN FERNANDEZ, ARANTZAZUAEROSOL DYNAMICS, INC., CA$518,991ZRG1
2017Endotoxin Neutralization as a Biomonitor for HIV Disease Progression2R44AI114445-02A1CHAMPION, KEITHBIODTECH, INC., AL$501,326ZRG1
2017Using Technology to Improve Clinical Counseling of Adolescent Risky Behaviors2R44DA037623-02A1SALERNO, JENNIFERPOSSIBILITIES FOR CHANGE, LLC, MI$499,508ZRG1
2017Monitoring Pesticide Exposure and Accumulation: An Improved Rapid Identifier for all Pesticide Classes2R44ES024617-02SPENCER, KEVIN MEIC LABORATORIES, INC., MA$489,112ZRG1
2017Drug Delivery Method for Sudden Sensorineural Hearing Loss2R44DC013534-02A1WEINBERG, IRVINGWEINBERG MEDICAL PHYSICS, LLC, MD$484,330ZRG1
2017Geostatistical software for space-time interpolation and uncertainty modeling2R44ES022113-02GOOVAERTS, PIERRE EBIOMEDWARE, MI$428,720ZRG1
2017Autonomous system supporting patient-specific transfer and discharge decisions1R43NR015945-01A1DAS, RITANKARDASCENA, INC., CA$347,772ZRG1
2017A novel 3D-ultrasound platform using traditional 2D probes1R43NS097208-01A1HAYES, THOMAS JAMESURSUS MEDICAL, LLC, PA$341,520ZRG1
2017Antithrombotic Therapy with No Bleeding Risk for PCI1R44HL135993-01CHEN, RIDONGAPT THERAPEUTICS, INC., IL$300,437ZRG1
2017Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN1R43CA206796-01A1NEMENOV, MIKHAIL I.LASMED, LLC, CA$300,000ZRG1
2017Development and Validation of a Collaborative Web-Based Quantitative Imaging and Dosimetry System for Radiopharmaceutical Therapy1R43CA213782-01FREY, ERIC C.GHALY, MICHAELRADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC, MD$300,000ZRG1
2017Selection of a device for intranasal administration of a mucosal vaccine for HSV-21R43AI129378-01YANG, KEJIANBIOMEDICAL RESEARCH MODELS, INC., MA$300,000ZRG1
2017Discovery of inhibitors of Zika virus1R43AI129009-01COBURN, GLEN ANDREWVENATORX PHARMACEUTICALS, INC., PA$299,999ZRG1
2017Screening for rAAV transduction enhancers1R43AI125043-01A1BOWLIN, TERRY L.MICROBIOTIX, INC, MA$299,999ZRG1
2017Targeting the checkpoint regulator VISTA for treatment of inflammatory disease1R44AI129182-01ROTHSTEIN, JAY LIMMUNEXT, INC., NH$299,938ZRG1
2017Enhancing cytarabine efficacy in leukemia through CDK8/19 inhibition1R43CA213629-01PORTER, DONALD C.SENEX BIOTECHNOLOGY, INC., SC$299,891ZRG1
2017A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus1R43AI129077-01CHO, HYUNDAECROSSLIFE TECHNOLOGIES, INC., CA$299,574ZRG1
2017Development of an oxygen delivery biotherapeutic for the preservation of myocardial function during pediatric cardiopulmonary bypass1R44HD094414-01FINEMAN, JEFFREY RKRTOLICA, ANAMALTEPE, EMINOMNIOX, INC., CA$298,396ZRG1
2017Aerosolized platinum nanoparticle chemotherapy for lung cancer1R43CA203142-01A1GROER, CHAD E.NANOPHARM, LLC, KS$298,065ZRG1
2017A Cytomegalovirus-based therapeutic vaccine for chronic hepatitis B1R44AI129232-01BRUENING, ERICTOMEGAVAX, INC., OR$297,434ZRG1
2017Aminospectinomycin antibacterials for the treatment of antibiotic-resistant gonorrhea and other bacterial STDs1R43AI129008-01BUTLER, MICHELLE M.MICROBIOTIX, INC, MA$296,845ZRG1
2017Novel Therapeutics for Endothelial Dysfunction1R43TR001867-01HSU, SHEAU-YU TEDDYADEPTHERA, LLC, CA$290,425ZRG1
2017Evaluate Efficacy of a JNK Lead Compound, IGP001, in an In Vivo Alzheimer’s Disease Model1R43AG054090-01A1CHEN, KAREN SANGIMAGO PHARMACEUTICALS, INC., WY$282,424ZRG1
2017Novel multifunctional oligosaccharide for treating sepsis and severe sepsis.1R43AI129164-01ACHARYA, SUCHISMITAAYUVIS RESEARCH, INC., TX$273,826ZRG1
2017Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment1R43NS090653-01A1ARENDASH, GARY WNEUROEM THERAPEUTICS, INC., AZ$255,391ZRG1
2017Direct sequencing of serum antibodies after infection1R43AI129082-01GUTHALS, ADRIANMAPP BIOPHARMACEUTICAL, INC., CA$255,046ZRG1
2017Serotype independent therapeutic vaccine for Streptococcus pneumoniae1R43AI129218-01AMAN, M JAVADINTEGRATED BIOTHERAPEUTICS, INC., MD$247,510ZRG1
2017Wearable technology to reduce risk of DVT and increase patient compliance1R43HL132624-01A1SCHWEGMAN, JEFFREYRECOVERY FORCE, LLC, IN$244,167ZRG1
2017Discriminating viral and bacterial meningitis infections with iDDS probes1R43AI129078-01SHAFER, DAVID AGENETAG TECHNOLOGY, INC., GA$242,611ZRG1
2017Development of a Homogeneous Screening Assay for the Tissue-Protective EPOR1R43TR001596-01A1MILLER, JAMES LSTATEGICS, INC., CA$242,013ZRG1
2017Estimating disease risk using genetic data1R43HG009089-01A1FURLOTTE, NICHOLAS A.23ANDME, INC., CA$241,905ZRG1
2017A novel biomaterial-based therapy utilizing auto-antigen and adjuvant for the amelioration of Type 1 Diabetes1R43AI129034-01MARSHALL, GREGORY PAULONEVAX, LLC, FL$238,328ZRG1
2017A mucosally targeted MERS-CoV vaccine produced in plants1R43AI122551-01A1WYCOFF, KEITHPLANET BIOTECHNOLOGY, INC., CA$236,488ZRG1
2017"Modulation of Immune Checkpoints by Self-Deliverable RNAi for Adoptive Cell Transfer"1R43CA213632-01WOLFSON, ALEXEYADVANCED RNA TECHNOLOGIES, LLC, CO$231,500ZRG1
2017Assembled Porous Silica Membranes for Biomolecule SPE1R43GM122098-01BOYES, BARRY EADVANCED MATERIALS TECHNOLOGY, INC., DE$231,421ZRG1
2017A Topical Nrf2 Activator for Oral Mucositis1R43DE026086-01A1HYBERTSON, BROOKS MICHAELPATHWAYS BIOSCIENCE, LLC, CO$229,248ZRG1
2017A Yeast based Immunotherapy against Clostridium difficile Infection1R43AI129044-01YANG, ZHIYONGFZATA, INC., MD$225,068ZRG1
2017FMRI Dynamic Phantom for Improved Detection of Resting-State Brain Networks1R44DA043277-01KRIEGSTEIN, ALANMUJICA-PARODI, LILIANNE RALA SCIENTIFIC INSTRUMENTS, INC., NY$225,028ZRG1
2017An interactive, patient-specific virtual surgical planning system for upper airway obstruction treatments1R43EB023121-01ENQUOBAHRIE, ANDINET ASMAMAWKITWARE, INC., NY$225,000ZRG1
2017Novel AMPK Activators for the Treatment of Neuropathic Pain1R43GM119596-01A1DAX, SCOTT LCERSCI THERAPEUTICS, INC., TX$225,000ZRG1
2017An interactive App to Promote Safe and Effective use of Opioids in Young Children Postoperatively1R43DA042645-01LEVINE, ROBERT JARCHIEMD, INC., FL$225,000ZRG1
2017Evaluation of Natural Products and Derivatives as Antimalarial Agents1R43AI128888-01ZHU, SHURENCASCADE THERAPEUTICS, INC., MD$225,000ZRG1
2017A Novel, Non-Cytotoxic, Epigenetic Therapeutic for Sickle Cell Disease1R44HL135896-01DESIMONE, JOSEPHSAUNTHARARAJAH, YOGENDENOVOTHERAPIES, LLC, OH$225,000ZRG1
2017Media-based youth e-cig prevention toolkit for community-based organizations1R44DA041004-01A1HOLTZ, KRISTEN DKDH RESEARCH AND COMMUNICATION, INC., GA$225,000ZRG1
2017Genome Mining the Full Diversity of the Actinomycete Biosynthetic Universe for Neomorph Antibiotic Discovery1R43AI129043-01GRAY, DANIELPHAN, LYWARP DRIVE BIO, INC, MA$225,000ZRG1
2017Practical Mass Spectrometry Upgrade for Identifying Fragile Protein Modifications by ECD1R43GM122131-01VOINOV, VALERY G.E-MSION, INC., OR$225,000ZRG1
2017Biosynthesis of novel and natural plant alkaloid compounds for drug production and discovery1R43AT009419-01HAWKINS, KRISTYANTHEIA, INC., CA$225,000ZRG1
2017ENaC inhibiting peptide for Cystic Fibrosis delivered by Dry Powder Inhaler1R43HL135951-01CROWDER, TIMOTHYSPYRYX BIOSCIENCES, INC., NC$225,000ZRG1
2017NeuroGoggle: A Portable Brain-based Device for Assessing Visual Function Deficits1R43EY027651-01ZAO, JOHN KAR-KINNGOGGLE, INC., CA$225,000ZRG1
2017A Rapid, Low-Cost Point of Care Diagnostic for detection of Zika virus RNA1R43AI129126-01USMANI-BROWN, SAHARL2 DIAGNOSTICS, LLC, CT$225,000ZRG1
2017Advances in contact lens materials to extend wear time for a new standard in vision correction and future medical devices1R43EY027239-01A1DOMSZY, ROMANINDUSTRIAL SCIENCE & TECHNOLOGY NETWORK, PA$225,000ZRG1
2017Plastic Parenteral Container with Superior Barrier Properties for Biologics1R43HL129622-01A1JONSEN, DANIEL EVERETTTRIBOFILM RESEARCH, INC., NC$224,993ZRG1
2017Mindfulness Mobile App to Reduce Adolescent Substance Use1R43DA043288-01SMITH, DANA KOREGON RES BEHAVIORAL INTERVENTION STRAT, OR$224,985ZRG1
2017Novel xenogeneic extracellular matrix biomaterial for cardiovascular prostheses1R43HL136003-01WONG, MAELENE LVIVITA TECHNOLOGIES, INC., CA$224,976ZRG1
2017Preclinical Evaluation of Ancestral Coagulation Factor VIII1R43HL135969-01DENNING, GABRIELADOERING, CHRISTOPHER BRADLEYSPENCER, H TRENTEXPRESSION THERAPEUTICS, GA$224,976ZRG1
2017Promoting AdheRence via Objective Technology to Assess Cystic Fibrosis Treatment (PROTRACT)1R43HL132650-01A1KREPKOVICH, EILEEN T.BARRON ASSOCIATES, INC., VA$224,966ZRG1
2017Rapid and Low- cost POC Assay for Zika Virus Diagnosis1R43AI129061-01WONG, SEASON S-SAI BIOSCIENCES, INC., TX$224,955ZRG1
2017Wireless System for Ambulatory Rodents to Measure Pressure and Volume in the Left Ventricle1R43HL132705-01A1RIEHLE, TIMOTHY H.KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT, MN$224,953ZRG1
2017Digital serology for parallel parasitic disease detection1R43AI129113-01DAUGHERTY, PATRICK SSERIMMUNE, INC., CA$224,950ZRG1
2017Continuous Data Collection and Analysis for Stroke Prevention using a Wearable Sensor1R43AG058516-01LICHTER, PATRICKKORONIS BIOMEDICAL TECHNOLOGIES CORPORAT, MN$224,942ZRG1
2017High-throughput screening of arrayed single cells for automated analysis of phenotypic heterogeneity1R43GM122149-01FORBES, ZACHARY GRAHAMCELLDOM, INC., CA$224,907ZRG1
2017Novel enzyme inhibitor screening platform using modified designer nucleosomes1R43GM119893-01A1SUN, ZU-WENEPICYPHER, INC., NC$224,881ZRG1
2017Comprehensive Eye Evaluation Algorithm: CEEvA1R43EY026832-01A1BAUMAN, WENDALL CMANIVANNAN, NIRANCHANAZAMORA, GILBERTOVISIONQUEST BIOMEDICAL, LLC, NM$224,791ZRG1
2017GC4419, an SOD Mimetic, as a Radiomodulator in Lung Cancer Patients Treated with SBRT1R44CA206795-01A1KEENE, JEFFERY LYNNSTORY, MICHAEL DEANGALERA THERAPEUTICS, LLC, PA$224,736ZRG1
2017Establishment of a patient-like mouse models of soft-tissue sarcoma sub-types1R43CA213649-01HOFFMAN, ROBERT MANTICANCER, INC., CA$224,700ZRG1
2017New Endothelial Cell-Based Assay to Assess Variability of Nitric Oxide Production in Humans1R43ES027716-01KINEV, ALEXANDERCREATIVE SCIENTIST, INC., NC$224,460ZRG1
2017Commercial Software Using High-throughput Computational Techniques to Improve Genome Analysis1R44HG009474-01KIEL, MARK JULINGENOMENON, INC., MI$224,417ZRG1
2017Sensitive and Portable Physician Office-Based Urine Analyzer to Tackle Prescription Drug Abuse1R43DA043325-01HEFFERNAN, MICHAEL JOHNBREVITEST TECHNOLOGIES, INC., TX$224,415ZRG1
2017Degradable hydrogel for retinal tamponade1R43EY027635-01BRAITHWAITE, GAVIN JAMESCAMBRIDGE POLYMER GROUP, INC., MA$224,397ZRG1
2017Sustained 3-Month Delivery of Olanzapine for Schizophrenia Maintenance Treatment1R43MH112240-01MARTIN, FRANCIS JOSEPHDELPOR, INC., CA$224,389ZRG1
2017Minimally Invasive Cardiac Sympathetic Denervation for Malignant Ventricular Arrhythmia1R44HL135957-01LEVIN, HOWARD DCORIDEA, LLC, NY$224,221ZRG1
2017Direct Conversion of Human Fibroblasts into Neuronal Cells by Small Molecules (hCiN)1R43DA041997-01A1ESMAELI-AZAD, BABAKCIBOTS, INC., CA$223,988ZRG1
2017Surgical Wound Closure Matrices for the Prevention of Superficial Incisional SSI1R43GM122226-01MEHTA, MANAVGEL4MED, INC., MA$223,866ZRG1
2017Development of multispecific antibodies for the treatment of Pseudomonas aeruginosa infection1R44AI129161-01HOLLANDS, ANDREW STEPHENINHIBRX, INC., CA$223,854ZRG1
2017Retinal image analysis software for neurodegenerative disease research1R43TR001890-01RUSSAKOFF, DANIELVOXELERON, LLC, CA$222,991ZRG1
2017Optical Dosimeter-guided Photodynamic Therapy1R43CA213607-01DAVIS, STEVEN JPHYSICAL SCIENCES, INC, MA$222,555ZRG1
2017A High School Program for Preventing Prescription Drug Abuse1R44DA043273-01GRIFFIN, KENNETH WNATIONAL HEALTH PROMOTION ASSOCIATES, NY$220,878ZRG1
2017The Oaks: A Mobile Exercise and Education Program for People with Osteoarthritis of the Knee1R44AG055341-01FLYNN, SHERYLBLUE MARBLE REHAB, INC., CA$220,137ZRG1
2017Optogenetic control over transgene expression for the therapy of brain and spine1R43MH110273-01A1MYAKISHEV-REMPEL, MAXLOCALIZED THERAPEUTICS, LLC, CA$220,083ZRG1
2017Microfluidic S-nitrosothiol Sensor1R43GM122152-01MCDUNN, JONATHAN EDWARDCLINICAL SENSORS, INC., NC$215,501ZRG1
2017Subcutaneous Replacement Enzymes for Fabry Disease1R43TR001884-01CAO, MINGJUKINETIQ, INC., CA$211,668ZRG1
2017Supporting Healthy Aging with a Phytochemical Combination that Acts at Multiple Control Points in the Nrf2 Activation Pathway1R43AG053128-01A1HYBERTSON, BROOKS MICHAELPATHWAYS BIOSCIENCE, LLC, CO$209,928ZRG1
2017Cost effective high-quality genome assembly for non-model organisms1R43HG009482-01TAYLOR, RYAN WALDOEND2END GENOMICS, LLC, CA$204,240ZRG1
2017Fully modified bispecific aptamer for effective wet AMD combination treatment1R43EY027634-01GONG, QIANGAPTITUDE MEDICAL SYSTEMS, INC., CA$202,821ZRG1
2017Targeting the alternative pathway to treat age-related macular degeneration1R43EY026860-01A1SCHRAMM, ELIZABETHSERION, INC., MO$198,151ZRG1
2017Fluorescent reporters for real-time single-cell Pol III transcription measurement1R43GM122166-01WU, KARENLUCERNA, INC., NY$176,165ZRG1
2017Increasing available choices for conjugate vaccine technology by producing carrier proteins in Scarab Genomics’ reduced genome E. coli strains1R44AI129149-01BLATTNER, FREDERICK RLANDRY, CHARLES FSCARAB GENOMICS, LLC, WI$154,222ZRG1
2017Enhancing CRISPR-based Therapeutic Interventions Via a Targeted Platform Tool1R43TR001897-01LAPPI, DOUGLAS AADVANCED TARGETING SYSTEMS, INC., CA$150,000ZRG1
2017A Metabologenomics Platform for Large-Scale, High-Throughput Natural Product Discovery1R43AT009417-01GOERING, ANTHONY WHITNEYMICROBIAL PHARMACEUTICALS, INC., IL$150,000ZRG1
2017Centralized assay datasets for modelling support of small drug discovery organizations1R43GM122196-01EKINS, SEANCOLLABORATIONS PHARMACEUTICALS, INC., NC$149,999ZRG1
2017Fixed site and wearable monitors for assessment of personal exposure to airborne chemicals1R43ES027736-01KADOSSOV, EVGUENIXPLOSAFE, LLC, OK$149,999ZRG1
2017Laboratory Bench-Top EXAFS with STJ Spectrometer1R43GM122163-01CARPENTER, MATTHEW HSTAR CRYOELECTRONICS, LLC, NM$149,997ZRG1
2017iCardioTox Profiler - Developing a Novel In Vitro Assay to Assess Cardiotoxicity Using a Panel of Patient-derived Cardiomyocytes1R43HL135916-01KIM, KEVIN JSTEM CELL THERANOSTICS, INC, CA$149,981ZRG1
2017Long non-coding RNA signatures to distinguish fibromyalgia syndrome from rheumatic diseases1R43AI129147-01AUNE, THOMAS M.SPURLOCK, CHARLES FLOYDIQUITY LABS, INC, TN$149,286ZRG1
2017Improved pulse oximetry performance using transmission optical flowmetry.1R43GM122132-01RICE, TYLERLASER ASSOCIATED SCIENCES, INC., CA$149,237ZRG1
2017Retinal birefringence imaging for pediatric vision screening1R43EY027633-01SHAKA, JUSTINWINSOR, ROBERTREBISCAN, LLC, MA$149,152ZRG1
2017A Phase I Clinical Trial: Binary Therapy with DM-CHOC-PEN and WBRT in Adults with Cancer Involving the CNS1R43CA213545-01MORGAN, LEE ROYDEKK-TEC, INC., LA$143,294ZRG1
2017A wearable tech app for Checkup&Choices1R43AA025502-01CAMPBELL, WILLIAM PCHECKUP AND CHOICES, LLC, NM$139,977ZRG1
2017High sensitive and specific, Point-of-use lateral flow strip for on-site test of cannabis intoxication1R43DA042664-01ZHOU, XICHUNVITAN-BIOTECH, LLC, CO$131,697ZRG1
2017Development of Multispecific Antibodies for the treatment of Methicillin Resistant Staphylococcus ‎aureus (MRSA) infection1R43AI129162-01HOLLANDS, ANDREW STEPHENINHIBRX, INC., CA$108,396ZRG1
2016Improved Oral P-selectin Blocker for Prophylactic Sickle Cell Disease Therapy2R44HL123059-02A1EMBURY, STEPHEN H.VANGUARD THERAPEUTICS, INC., CA$1,668,155ZRG1
2016Development of an ophthalmic diagnostic probe for neurodegenerativedisorders2R44AG050454-02SARRAF, STELLAAMYDIS DIAGNOSTICS, INC., CA$1,647,908ZRG1
2016Characterization of a low mutation rate E. coli in extended fermentation2R44GM105177-02 · under PA-14-071BLATTNER, FREDERICK RFRISCH, DAVID ASCARAB GENOMICS, LLC, WI$1,554,424ZRG1
2016Arenavirus Antiviral Lead Optimization2R44AI112097-03 · under PA-14-071HENKEL, GREGORY WILLIAMPLEWE, MICHAEL BRUNOARISAN THERAPEUTICS, INC., CA$1,500,000ZRG1
2016Advanced morphological analysis of cerebral blood flow for acute concussion diagnosis and return-to-play determination2R44NS092209-02HAMILTON, ROBERTNEURAL ANALYTICS, INC., CA$1,500,000ZRG1
2016Novel drug VS-105 for treatment of osteoporosis2R44AR065247-02 · under PA-14-071WU-WONG, JINSHYUN RUTHVIDASYM, INC., SD$1,480,983ZRG1
2016Multi Source E-Beam kV X-Ray Tube for Image-Guided Radiotheraphy2R44CA192498-02BOYD, DOUGLAS PTELESECURITY SCIENCES, INC., NV$1,254,926ZRG1
2016A Proton Radiography System for Optimization of Proton Therapy2R44CA203499-02DEJONGH, DON FPROTONVDA LLC, IL$1,248,811ZRG1
2016Restoration of free radical homeostasis: novel therapy of septic shock2R44GM100503-02A1SALZMAN, ANDREW LURIERADIKAL THERAPEUTICS, INC., MA$1,248,631ZRG1
2016Integrated System for FFPE Sample Preparation2R44CA186384-02A1KELLOGG, GREGORY JOHNCOVARIS, INC., MA$1,227,038ZRG1
2016Validation of a human in vitro system of hepatic steatohepatitis2R44DK100136-02A1WAMHOFF, BRIAN ROBERTHEMOSHEAR THERAPEUTICS, LLC, VA$1,210,475ZRG1
2016Development and Validation of the Miya Model, A Simulator Designed to Train Vaginal Surgery Techniques2R44HD084151-02CHEN, CHI CHIUNG GRACEDESTEPHANO, CHRISTOPHERKAMMIRE, LESLIELOCKROW, ERNESTMATTHEWS, CATHERINE ANNMIYAZAKI, DOUGLAS W.NIHIRA, MIKIOMIYAZAKI ENTERPRISES, LLC, NC$1,169,878ZRG1
2016Shape Memory Polymer Vascular Occlusion Device for the Treatment of Venous Insufficiency Phase II2R44EB022016-02A1LANDSMAN, TODDSHAPE MEMORY MEDICAL INC., CA$1,162,700ZRG1
2016A Vaccine for Schistosomiasis, "SchistoShield"2R44AI103983-03A1 · under PA-14-071CARTER, DARRICK ALBERTSIDDIQUI, AFZAL APAI LIFE SCIENCES, INC., WA$1,159,786ZRG1
2016Reducing Brain Injury After Focal Ischemia Using a Nitric Oxide-Neutral Oxygen Carrier2R44NS076272-02A1CARY, STEPHENLE MOAN, NATACHAOMNIOX, INC., CA$1,115,299ZRG1
2016Improving red blood cell transfusion through systems biology2R44HL123074-02 · under PA-14-071BORDBAR, AARASHSINOPIA BIOSCIENCES, INC., CA$1,029,290ZRG1
2016Video Rate optical verification tool for radiotherapy treatment plans2R44CA199681-02WARE, WILLIAMDOSEOPTICS, LLC, NH$1,016,414ZRG1
2016Modulated Imaging in Comprehensive Assessment of Diabetic Foot Ulcer Development and Healing2R44DK094625-02A1CUCCIA, DAVID JMAZHAR, AMAANMODULATED IMAGING, INC., CA$1,015,160ZRG1
2016CorBand: A novel wearable wrist sensor for heart failure remote monitoring2R44HL125001-02NAIMA, REZARETHINK MEDICAL, INC., CA$1,009,410ZRG1
2016Development and Commercialization of an Innovative Rapid HIV-1 Incidence Assay2R44AI114365-02A1MINK, RONALD WILLIAMSEDIA BIOSCIENCES CORPORATION, OR$1,000,000ZRG1
2016Plant-derived HIV neutralizing mAbs for passive immunotherapy in newborn macaques2R44AI081621-04A1ROSENBERG, YVONNE JPLANTVAX, INC., MD$1,000,000ZRG1
2016TP508: A New Drug for Mitigating Lethals Effects of Radiation Exposure2R44AI086135-05CARNEY, DARRELL H.SOWER, LAURIE ECHRYSALIS BIOTHERAPEUTICS, INC., TX$1,000,000ZRG1
2016Optimization of a clinical stage nanoparticle drug delivery platform2R44CA186410-02A1BROWN, BOB D.DICERNA PHARMACEUTICALS, INC., MA$1,000,000ZRG1
2016Customized Nanotechnology Based Treatment of Oral Cancer2R44DE023725-02 · under PA-14-071GOLDBERG, MANIJEH NPRIVO TECHNOLOGIES, LLC, MA$999,997ZRG1
2016Therapeutic Antibodies for Biofilm Infections2R44AI120425-02KAUVAR, LAWRENCE MICHAELTRELLIS BIOSCIENCE, INC., CA$999,628ZRG1
2016Preventing and treating RSV pneumonia in immunocompromised cancer patients2R44HL118926-02 · under PA-14-071SCOTT, BRENTONPULMOTECT, INC, TX$999,372ZRG1
2016Innovative Optical System for Hemagglutination Assays2R44AI106054-03A1ROWLEN, KATHY LINDEVR, INC., CO$996,634ZRG1
2016Preclinical development of a potent D-peptide RSV inhibitor2R44AI098197-03A1WELCH, BRETT DNAVIGEN, INC., UT$992,263ZRG1
2016Overcoming Tramadol Resistance In CYP2D6 Poor Metabolizers: A Phase 1 Trial Demonstrating Analgesic Superiority of Omnitram to Tramadol in Subjects Coadministered Paroxetine2R44DA027304-05KAHN, STUART JZEBALA, JOHN ASYNTRIX BIOSYSTEMS, INC., WA$990,418ZRG1
2016A method for preparing unbiased miRNA sequencing libraries (miR-ACS)2R44HG007788-02A1KAZAKOV, SERGEI ASOMAGENICS, INC., CA$990,251ZRG1
2016Universal Attenuated Sporozoite Vaccine and Challenge System2R44AI058375-09HOFFMAN, STEPHEN LEVSANARIA, INC., MD$989,298ZRG1
2016Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Application2R44EY026864-05SOLANKI, KAUSHALEYENUK, INC., CA$984,026ZRG1
2016Radiation Sterilizable Small Size RFID Tags for Biomedical Samples2R44OD020162-02DAVIDOWITZ, HANANELBIO TILLION, LLC, NJ$961,641ZRG1
2016SAMBA HIV-1 Semi-quantitative whole blood test for resource limited settings2R44AI097120-05LEE, HELEN HDIAGNOSTICS FOR THE REAL WORLD, LTD, CA$951,508ZRG1
2016A Cytomegalovirus-based therapeutic vaccine against oncogenic human papillomaviruses2R44CA180177-02BRUENING, ERICTOMEGAVAX, INC., OR$948,184ZRG1
2016Compact super-directional microphone array to improve hearing in background noise2R44DC014169-02ELKO, GARY W.MH ACOUSTICS, LLC, NJ$945,095ZRG1
2016Validation and qualification of an ex vivo human cardiac tissue-based assay for the assessment of the potential cardiotoxicity of pharmaceutical compounds2R44TR001133-02A1GHETTI, ANDREAANABIOS CORPORATION, CA$945,014ZRG1
2016Safe and effective anti CD154 antibodies for therapeutic intervention2R44AI098261-05ROTHSTEIN, JAY LIMMUNEXT, INC., NH$912,191ZRG1
2016Development of Monoclonal Antibodies to Treat Pancreatic Cancer2R44CA174025-02SUREBAN, SRIPATHI MCOARE BIOTECHNOLOGY, INC., OK$905,989ZRG1
2016Activate Silent and Cryptic Intact Fungal SM Gene Clusters through FACs for Novel Antibiotics Discovery2R44AI118086-02BOK, JIN WOOKELLEHER, NEIL LWU, CHENGCANG CHARLESINTACT GENOMICS, INC., MO$900,553ZRG1
2016Low Insertion Force Epidural, Actuated Needle System for Enhanced Control and Tactile Feel During Epidural Insertion2R44GM085844-04A1 · under PA-14-071MULVIHILL, MAUREEN L.ACTUATED MEDICAL, INC., PA$898,850ZRG1
2016Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds II2R44GM103402-03PENNISI, KENNETH JCOMPACT MEMBRANE SYSTEMS, INC., DE$896,762ZRG1
2016High Speed Multiphoton Multifocal Whole Brain Imaging2R44NS087767-02RAGAN, TIMOTHY M.TISSUEVISION, INC., MA$885,211ZRG1
2016Kinome-wide Cell-Based Assays2R44GM109740-02 · under PA-14-071ZUTSHI, REENALUCEOME BIOTECHNOLOGIES, LLC, AZ$873,704ZRG1
2016Interactive Technology for Hearing Aid Education and Acceptance2R44AG045947-02A1LETZT, ALANHEALTHCARE TECHNOLOGIES AND METHODS, VA$861,278ZRG1
2016Therapeutic Reversal of Endothelial Dysfunction in Atherogenesis2R44HL118826-03A1ADAMS, WILLIAM JAMESGARCIA-CARDENA, GUILLERMORIPARIAN PHARMACEUTICALS, INC., MA$857,294ZRG1
2016Development of SUPR peptides as PET Imaging Agents for Her2+ Breast Cancer2R44CA206771-02FIACCO, STEPHENMILLWARD, STEVEN WEVORX TECHNOLOGIES, INC., CA$855,568ZRG1
2016Development of the RXR agonist IRX4204 to treat Multiple Sclerosis and other Immune related Diseases2R44AI112512-02A1CHANDRARATNA, ROSHIO THERAPEUTICS, INC., CA$854,395ZRG1
2016Intervening to Prevent Youth Access to Marijuana Phase II2R44DA038933-02BULLER, DAVID BKLEIN BUENDEL, INC., CO$848,974ZRG1
2016Refinement of an Autocidal Gravid Ovitrap for mass-manufacturing2R44AI115782-02BANFIELD, MICHAEL GILBERTBESS, EMILIEBANFIELDBIO INC., WA$848,707ZRG1
2016One Step, POC Sample to Answer Process for RNA Analysis Outside the Laboratory2R44GM106496-02MUELLER, JOHN ELYNNTECH, INC., TX$833,462ZRG1
2016Ocular Flare Meter (OFAM) Development Phase II2R44EY022548-02A1MENON, NARESHCHROMOLOGIC, LLC, CA$830,773ZRG1
2016High throughput laboratory X-ray illumination system for protein crystallography and screening2R44GM112287-02YUN, WENBINGSIGRAY, INC., CA$825,315ZRG1
2016Malarial Retinopathy Screening System for Improved Diagnosis of Cerebral Malaria2R44AI112164-03A1HARDING, SIMONJOSHI, VINAYAK SLEWALLEN, SUSANVISIONQUEST BIOMEDICAL, LLC, NM$821,709ZRG1
2016Development of a treatment for voiding dysfunction in spinal cord injured patients2R44HD080263-02A1MARSON, LESLEYDIGNIFY THERAPEUTICS, LLC, NC$818,347ZRG1
2016Novel DNA-Launched Attenuated Vaccine for VEE Virus SBIR Phase II2R44AI094863-03A1 · under PA-14-071PUSHKO, PETER M.MEDIGEN, INC., MD$811,565ZRG1
2016Novel Therapeutic Approach to Hypercholesterolemia Using Anti-PCSK9 Selected Immune Repertoires2R44HL121909-02 · under PA-14-071SHIMKETS, RICHARD AUGUSTABEOME CORPORATION, GA$809,592ZRG1
2016Portable Transdermal Acoustic Patch for Delivery of Large Molecules to Improve HIV Patient Medication Regime Compliance by Elimination of Side-Effects, Including Injection Site Reactions2R44AI080335-04MULVIHILL, MAUREEN L.ACTUATED MEDICAL, INC., PA$808,204ZRG1
2016Safety Studies for Clinical Trials of a Botanical Drug for Sickle Cell Disease2R44HL119086-02 · under PA-14-071SWIFT, ROBERTINVENUX, LLC, CO$807,410ZRG1
2016SELF-NEUTRALIZING OLIGONUCLEOTIDES WITH ENHANCED CELLULAR UPTAKE2R44GM109517-02TABATADZE, DAVID RZATA PHARMACEUTICALS, INC., MA$796,420ZRG1
2016Novel Debridement for Necrotic Tissue2R44GM113284-02A1LEUNG, KELLY XSALAMONE, JOSEPH C.ROCHAL INDUSTRIES, LLC, TX$789,877ZRG1
2016A New Technique for Diabetic Foot Ulcers2R44DK105692-02CHIEN, SUFANNOVERATECH, LLC, KY$781,613ZRG1
2016Development and validation of a human brown adipocyte system2R44DK103479-02LEA-CURRIE, YOLANDA RENEEVAN KANEGAN, MICHAEL JOSEPHZEN-BIO, INC., NC$777,915ZRG1
2016Microfabricated Cochlear Electrode Array2R44DC012741-02JOHNSON, ANGELIQUEMEMSTIM, LLC, KY$767,241ZRG1
2016Improving Clinical Encounter Communications to Enhance Minority Diabetes Care2R44MD009559-02ZACHARY, WAYNE WSTARSHIP HEALTH TECHNOLOGIES, PA$766,020ZRG1
2016Nanowire Sensor Array-based Assay for Early Diagnosis of Alzheimer's Disease2R44AG046059-02A1ALAM, MAKSUDULINNOSENSE, LLC, CA$764,989ZRG1
2016Child Safety Seat with Advanced Harness System2R44HD083878-02SEIFERT, SARAMINNESOTA HEALTHSOLUTIONS CORPORATION, MN$764,633ZRG1
2016The VesiVax® System: Vaccine Development Made Easy2R44AI094770-03A1HO, SAMONMOLECULAR EXPRESS, INC., CA$762,253ZRG1
2016Ultra-sensitive method for HIV p24 antigen detection2R44AI083169-04A1BYSTRYAK, SIMONALLIED INNOVATIVE SYSTEMS, LLC, NJ$761,372ZRG1
2016A high throughput, high resolution, and high sensitivity scanning X-ray fluorescence microprobe for elemental mapping in cell cultures and tissues for medical research and diagnosis2R44GM112413-02 · under PA-14-071YUN, WENBINGSIGRAY, INC., CA$759,237ZRG1
2016Mass Spectrometric Bead-Imaging of Off-Target Drug Interactions2R44GM105249-03LIM, MARKAMBERGEN, INC, MA$753,500ZRG1

Showing the 200 most recent of 2,074 awards.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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