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NIH funding notice PA-16-302

PHS 2016-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Closed on April 5, 2017.

Posted
June 3, 2016
Close date
April 5, 2017
Activity codes
R43, R44
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, DPCPSI, ORIP, CGH, NCBDDD, NCCDPHP, NCEZID, NCHHSTP, NCIRD, NCIPC, NIOSH, CBER, CDER, CFSAN, CDRH, CVM, CPI, OOPD, OPRE

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-15-269 PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  2. 2 steps back: PA-14-071 PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  3. 3 steps back: PA-13-234 Reissue PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  4. 4 steps back: PA-13-088 PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  5. 5 steps back: PA-12-088 PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  6. 6 steps back: PA-11-096 PHS 2011-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  7. 7 steps back: PA-10-050 PHS 2010-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  8. 8 steps back: PA-09-080 PHS 2009-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Replaced by PA-17-302.

Who won it before

2,800 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $993,526,938 in first-year total cost, median $225,000.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-G (12)]161
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]134
  3. Special Emphasis Panel[ZRG1 ETTN-M (11)]124
  4. Special Emphasis Panel[ZRG1 RPHB-C (10)]115
  5. Special Emphasis Panel[ZRG1 IDM-V (12)]106

Most frequent institutions

  1. PANORAMA RESEARCH, INC.21
  2. AFFINERGY, LLC18
  3. PHYSICAL SCIENCES, INC17
  4. PROGENRA, INC.17
  5. 3-C INSTITUTE FOR SOCIAL DEVELOPMENT13
Competing awards under PA-16-302 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Commercialization of HaploSeq as a Service (HaaS) for generating chromosome-span phased genome and exome sequence information2R44HG008118-04A1DIXON, JESSE RLAURENT, LOUISE CHANGSELVARAJ, SIDDARTHARIMA GENOMICS, INC., CA$1,573,140ZRG1
2018Small Molecule Treatments to Enhance Neurological Recovery After Stroke2R44NS095381-02FINKLESTEIN, SETH PSTEMETIX, INC., MA$1,354,461ZRG1
2018Development of a Yellow Fever Vaccine for a Vulnerable Population2R44AI079898-06AMANNA, IAN JAMESSLIFKA, MARK KNAJIT TECHNOLOGIES, INC., OR$1,248,114ZRG1
2018Wearable Vibration Device to Prevent Bone Loss in Postmenopausal Women2R44AG046005-02BILEK, LAURA DIANEBURNETT, DANIEL ROGERSTHERANOVA, LLC, CA$1,146,609ZRG1
2018Device for rapid extraction of rare pathogens from raw samples2R44AI124930-02FISHER, JAY KENNETHREDBUD LABS, INC., NC$1,140,832ZRG1
2018A Novel Test to Measure Latent Virus in HIV-1 Infected Patients2R44AI124996-02LAIRD, GREGORY MICHAELACCELEVIR DIAGNOSTICS, LLC, MD$1,000,000ZRG1
2018Development of a kit for the targeted depletion of abundant sequencesfromDNA/RNA libraries2R44AI124933-03CARPENTER, MEREDITH LAURENARC BIO, LLC, MA$998,921ZRG1
2018Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine2R44AI114331-02A1BAGLEY, KENNETH CPROFECTUS BIOSCIENCES, INC., MD$993,161ZRG1
2018Evaluating the impact of novel inhibitors of nuclear pore export in SLE2R44AI124949-02LANDESMAN, YOSEFTAMIR, SHARONKARYOPHARM THERAPEUTICS, INC., MA$992,511ZRG1
2018Development of Molecular Diagnostic Test for Early Onset of Lyme disease2R44AI114009-02SCHUTZER, STEVEN EBIOSCIENCE DEVELOPMENT, INC., NY$988,413ZRG1
2018Aerosol Delivery of Surfactant for ARDS2R44HL127834-02A1YEATES, DONOVAN BYRONKAER BIOTHERAPEUTICS CORPORATION, CA$986,436ZRG1
2018Multiplexed Bead-based In Vitro Pediatric Allergy Test2R44AI100424-06LIM, MARKAMBERGEN, INC, MA$937,987ZRG1
2018High-throughput methyltransferase assays using recombinant nucleosome substrates2R44GM117683-02A1SUN, ZU-WENEPICYPHER, INC., NC$903,808ZRG1
2018Development of a novel highly effective influenza vaccine2R44AI109925-03BILSEL, PAMUKSARAWAR, SALLY R.FLUGEN, INC., WI$834,285ZRG1
2018Miniaturized Stopped-Flow Reaction Microcalorimeter for Biomedical Applications2R44GM113279-02A1BROWN, RICHARD KENNETHCAPE BIORESEARCH, INC., MA$775,488ZRG1
2018Over-the-Wire Device for Immediate and Complete Peripheral Artery Occlusion2R44HL124832-02A1FRANANO, F. NICHOLASARTIO MEDICAL, INC., KS$765,897ZRG1
2018Ophthalmic drug delivery using a multi-layer contact lens design that enables targeting, constant-rate release and failure protection2R44EY026850-02A1YANG, ARTHURLYNTHERA CORPORATION, PA$754,785ZRG1
2018Wireless Sensor Inserts for Combating Incontinence-Associated Dermatitis2R44NR014614-02A1PROKOPUK, NICHOLASJPTECHNOLOGIES, INC., CA$750,000ZRG1
2018The Variant Explorer: a cloud-based data integration and visualization system for improving clinical interpretation of sequenced genetic variants.2R44GM117644-02XU, XINGSOLVE, INC., NY$748,556ZRG1
2018Comprehensive but simple encoding of bioassays to accelerate translational drug discovery2R44TR000185-04A1BUNIN, BARRY ACOLLABORATIVE DRUG DISCOVERY, INC., CA$744,321ZRG1
2018Tools for drug efficacy studies in perfused tissue models2R44TR001286-02VUKASINOVIC, JELENALENA BIOSCIENCES, INC., GA$724,224ZRG1
2018Effect of Repeated Administration of G-CSF on Hot Flashes and Other Vasomotor Symptoms of Menopause1R43AG056209-01A1DUKE, RICHARD CMENOGENIX, INC., CO$693,360ZRG1
2018miR-SEQ: Highly efficient targeted quantification of extracellular miRNAs by Next Generation Sequencing2R44GM115124-03BARBERAN-SOLER, SERGIOSOMAGENICS, INC., CA$623,228ZRG1
2018Clinical optical coherence tomography for retinal metabolic imaging2R44EY026466-02KURANOV, ROMANOPTICENT, INC., IL$617,592ZRG1
2018Rapid response toxicology prediction platform2R44ES026909-02MYATT, GLENN JOHNLEADSCOPE, INC., OH$612,360ZRG1
2018CFI Pathogen Inactivation of Human Plasma Units1R44HL137605-01A1CASTOR, TREVOR P.OCHIENG, WASHINGTONEAPHIOS CORPORATION, MA$599,617ZRG1
2018Low-temperataure plasma decontamination of pharmaceutical manufacturing fill/finish operations2R44TR001847-02GALBALLY-KINNEY, KRISTIN LPHYSICAL SCIENCES, INC, MA$583,124ZRG1
2018Improving Patient Outcomes through Tracking and Displaying the Disinfection Status of Equipment and Area2R44NR016638-02STIBICH, MARK AXENEX DISINFECTION SERVICES, LLC, TX$564,057ZRG1
2018New Technology to Improve Chemotherapy Safety for Cancer Patients and Health Workers1R43CA224598-01SUNKARA, PRASADJ AND J SOLUTIONS, INC., IA$548,377ZRG1
2018A Computer Tool for Aiding in Accurate Assessment of Indeterminate Lung Nodules2R44CA203058-02A1MENG, XININTERNATIONAL INTELLIGENT INFOR/SOLU/LAB, PA$529,613ZRG1
2018Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina2R44EY023481-02FERGUSON, R DANIELPHYSICAL SCIENCES, INC, MA$527,107ZRG1
2018Use of DNATrax and high fidelity computational methods to model transport of contaminants in urban environments2R44ES025070-02ZOGRAFOS, ANTONIOSSAFETRACES, INC., CA$523,978ZRG1
2018Advancing Human Health by Lowering Barriers to Electrophysiology in Genetic Model Organisms2R44GM119906-02LOCKERY, SHAWN RMCCORMICK, KATHRYN EROBERTS, WILLIAM MWEEKS, JANIS CNEMAMETRIX, INC., OR$510,448ZRG1
2018Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager2R44EY024186-02A1MULLER, MATTHEW SAEON IMAGING, LLC, IN$505,350ZRG1
2018Improving drug safety for pregnant women by delivering current and authoritative information via mobile devices2R44DD001127-02MARKHAM, GLENRIGHTANSWER.COM, INC., MI$499,961ZRG1
2018Development and validation of a novel non-invasive device for measuring the mechanical properties of cortical bone1R43AG058312-01CLARK, BRIAN CDICK, ANDREWLOUCKS, ANNE BOSTEODX INC., OH$477,486ZRG1
2018A Computer Model of Renal Physiology for use as a FDA Medical Device Development Tool2R44FD005669-02PRUETT, WILLIAM ANDREWHC SIMULATION, LLC, MS$441,039ZRG1
2018PIKFYVE antagonism as a therapy for C9ORF72-ALS/FTD1R44NS105156-01ALWORTH, SAMUEL VZHOU, HONGYANACURASTEM, INC., CA$433,105ZRG1
2018Development of an Anti-Embolic Micromesh Carotid Stent1R43HL140895-01KEALEY, COLIN PATRICKNEUROSIGMA, INC., CA$415,743ZRG1
2018Preclinical Testing of Splice Modulating Oligonucleotides Targeting SCN8A to Treat Dravet Syndrome1R43NS105291-01TALLENT, MELANIE KLIFESPLICE PHARMA, LLC, PA$389,793ZRG1
2018Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples1R41MH115642-01CHAMPAIGNE, KEVIN DCIRCA BIOSCIENCE, LLC, SC$371,711ZRG1
2018A Phase 2a Multicenter, Randomized, Vehicle-Controlled, Dose Escalating Study to Evaluate the Safety, Efficacy and Pharmacokinetics of CBT-001 Ophthalmic Solution in Pterygium Patients1R44EY028784-01NI, JINSONGCLOUDBREAK THERAPEUTICS, LLC, CA$326,960ZRG1
2018PLGA encapsulated polyphenols to ameliorate IBD.1R43AT009800-01AUCI, DOMINICKDRYDEN, GERALD WTHERAPYX, INC., NY$320,159ZRG1
2018Remodeled glycoprotein for broad protection against ebolaviruses1R43AI136229-01AMAN, M JAVADINTEGRATED BIOTHERAPEUTICS, INC., MD$302,469ZRG1
2018Aptamer Beacons For High-Throughput Assay Development1R43GM126724-01KEOGH, MICHAEL-CHRISTOPHEREPICYPHER, INC., NC$300,244ZRG1
2018Culture-free identification of pathogens common in endocarditis directly from patient specimens1R43AI136064-01SINGER, ALONHELIXBIND, INC., MA$300,000ZRG1
2018UroLogic: Rapid, Near-to-Care Identification and Antimicrobial Susceptibility Testing of Microbes in Urine Specimens from Outpatients with Suspected Urinary Tract Infection1R43AI127015-01A1CHURCHILL, BERNARD MMICROBEDX, INC., CA$300,000ZRG1
2018Cpf1-mediated inactivation of an AAV transgene1R43AI136163-01ALPERT, MICHAEL DAVIDZHONG, GUOCAIEMMUNE, INC, FL$300,000ZRG1
2018Development of highly potent human monoclonals for RSV immunoprophylaxis1R43AI136272-01ZEITLIN, LARRYMAPP BIOPHARMACEUTICAL, INC., CA$300,000ZRG1
2018Low Cost, Rapid Molecular Diagnostic for Chlamydia and Gonorrhea at the Point-of-Care1R43AI136161-01PAIS, ANDREANOVEL MICRODEVICES, LLC, MD$300,000ZRG1
2018Point of care assay for serodiagnosis of Leptospirosis1R43AI136551-01GOMES-SOLECKI, MARIAIMMUNO TECHNOLOGIES, INC., TN$300,000ZRG1
2018Development, GMP manufacture, and quality control release of a triple knock out genetically attenuated Plasmodium falciparum sporozoite vaccine1R43AI136219-01HOFFMAN, STEPHEN LEVSANARIA, INC., MD$299,999ZRG1
2018Point-of-care diagnostic test for T. cruzi (Chagas) infection1R43AI136172-01LEVIN, ANDREW E.KEPHERA DIAGNOSTICS, LLC, MA$299,999ZRG1
2018Restoring Beta-lactam efficacy against methicillin-resistant Staphylococci1R44AI136213-01ROEMER, TERRYPROKARYOTICS, INC., NJ$299,999ZRG1
2018Humanized Anti-Renalase Antibodies for Unresectable Melanoma1R43CA224463-01BERKOWITZ, BARRY ADESIR, GARY V.KLUGER, HARRIET M.BESSOR PHARMA, LLC, MA$299,996ZRG1
2018An antigen-detection assay to diagnose Babesia microti infection1R43AI136118-01LEDIZET, MICHELL2 DIAGNOSTICS, LLC, CT$299,975ZRG1
2018A Noninvasive Prenatal Testing Platform for Aneuploidy at Five Weeks of Gestation1R43HD094405-01ARMANT, DAVID RANDALLDREWLO, SASCHAKADAM, LEENAKOHAN-GHADR, HAMID-REZACRADLE GENOMICS, INC., CA$299,969ZRG1
2018BT-11: A First-in-class Oral Therapeutic for Inflammatory Bowel Disease1R44AI134163-01A1BASSAGANYA-RIERA, JOSEPBIOTHERAPEUTICS, INC., VA$299,576ZRG1
2018Discovery of Yellow Fever Virus-Specific Epitopes for Development of an Accurate Serodiagnostic Assay1R43AI136197-01CAMERINI, DAVIDIMMPORT THERAPEUTICS, INC., CA$299,564ZRG1
2018Inhibitors of virus glycoprotein-LAMP1 receptor binding for Lassa virus therapy1R43AI136188-01LIU, GAIMICROBIOTIX, INC, MA$299,400ZRG1
2018Targeting Exonuclease Resistant RNA to Develop Zika Virus Therapeutics1R43AI136190-01KIMSEY, ISAAC JNYMIRUM, INC., MI$299,236ZRG1
2018Papillomavirus-like Particles (VLP) as Broad Spectrum Human Papillomavirus (HPV) Vaccines1R44AI136236-01WANG, JOSHUA WEIYUANPATHOVAX, LLC, MD$299,068ZRG1
2018FAST platform for same-shift, complete antibiotic menu antibiotic susceptibility testing1R43AI136125-01STERN, ERICSELUX DIAGNOSTICS, INC., MA$298,851ZRG1
2018Robust Small Animal Oxygen Imager to Model Enhanced Cancer Treatment1R43CA224840-01EPEL, BORISKOTECHA, MRIGNAYANIO2M TECHNOLOGIES, LLC, IL$298,245ZRG1
2018Safety, tolerability and efficacy of a novel sustained release analog of vasoactive intestinal peptide, PB1046, in patients with pulmonary arterial hypertension1R44HL140690-01LEE, JOHNPHASEBIO PHARMACEUTICALS, INC., PA$297,765ZRG1
2018Real-Time Salivary Testosterone and Extension to Mobile Application and Multiple Biomarker Quantification Capability1R43DA043293-01A1SLOWEY, PAUL DESMONDOASIS DIAGNOSTICS CORPORATION, WA$294,373ZRG1
2018Device for rapid, on-chip, sample-to-answer bacterial identification and drug susceptibility testing1R43AI136461-01FISHER, JAY KENNETHREDBUD LABS, INC., NC$294,357ZRG1
2018Form factor determination for the Talon microIPG system to treat Chronic Migraine1R43NS102302-01A1DULAK, GARYHOFFMANN, DREWNEOGENESIS TECHNOLOGIES, LLC, CA$287,154ZRG1
2018Nonsense Suppressing Drugs for Rett Syndrome1R43NS100227-01A1KOZIKOWSKI, ALAN P.STARWISE THERAPEUTICS, LLC, IL$282,726ZRG1
2018Reversing/Blocking T cell suppression by extracellular vesicles as cancer therapy1R43CA224602-01A1BHATTA, MAULASRIIMMUNE MODULATORY THERAPIES, LLC, NY$280,928ZRG1
2018PERIPHERALLY-RESTRICTED LONG-ACTING SOMATOSTATIN RECEPTOR TYPE 4 (LA-SSTR4) AGONISTS FOR PAIN1R43DA045410-01RIVIERE, PIERREPEPTIDE LOGIC, LLC, CA$279,411ZRG1
2018Preclinical small animal imaging platform for detection and quantification of early metastasis1R43CA224824-01ERMILOV, SERGEY APHOTOSOUND TECHNOLOGIES, INC., TX$279,143ZRG1
2018A Novel Inhibitor of the Classical Pathway of Complement1R43HL140716-01OLIVO, PAUL DAVIDANTHROBIO, INC., MO$254,235ZRG1
2018Preclinical development of an intravaginal ring for the sustained release of Pritelivir for the treatment and prophylaxis of Genital Herpes in women1R43AI136201-01SMITH, THOMAS J.AURITEC PHARMACEUTICALS, INC., CA$251,190ZRG1
2018Demonstrating Utility of a Non-Infectious Minute Virus of Mice-Virus Like Particle for Predicting Viral Clearance during Biopharmaceutical Process Development1R43TR002231-01A1CETLIN, DAVIDMOCKV SOLUTIONS, INC, MD$250,000ZRG1
2018Identification of lead chemical scaffolds targeting opioid receptor heteromers.1R43DA045411-01YEKKIRALA, AJAY SBLUE THERAPEUTICS, INC., MA$249,685ZRG1
2018Middle-ear reflex testing using WAI1R43DC016780-01HOOD, LINDA J.JENG, PATRICIA SMIMOSA ACOUSTICS, IL$245,733ZRG1
2018Creating Live Interactions to Mitigate Barriers (CLIMB): A Mobile Intervention to Improve Social Functioning in People With Schizophrenia1R43MH114765-01A1BIAGIANTI, BRUNOPOSIT SCIENCE CORPORATION, CA$245,571ZRG1
2018Less is More: Context-relevant views of EHRs1R43AG058357-01BOXWALA, AZIZ AELIMU INFORMATICS, INC., CA$243,998ZRG1
2018Preparation and development of a stabilized C3 analog for the treatment of paroxysmal nocturnal hemoglobinemia1R43HL139170-01A1FRITZINGER, DAVID CHARLESCASCADE BIOTECHNOLOGY, INC., NJ$240,748ZRG1
2018Tortuous vascular accessibility with a novel coaxial active deflectable microcatheter1R44HL137521-01A1TULLY, STEPHENAGILE DEVICES, INC., MA$233,642ZRG1
2018Antimicrobial Intravascular Catheter Lock Solutions Based on Endogenous Nitric Oxide Release Agent1R43AI136182-01MARTIN, GLENNNOTA LABORATORIES, LLC, MI$233,275ZRG1
2018Development of an oral drug targeting SUMOylation1R43CA217349-01A1CEE, VICTORSUVALENT THERAPEUTICS, INC., CA$232,759ZRG1
2018Preclinical development of Novo29, a new antibiotic1R43AI136137-01LING, LOSEE LUCYNOVOBIOTIC PHARMACEUTICALS, LLC, MA$231,409ZRG1
2018A Rapid, Near Patient System for Small Blood Volume Testing of Ammonia, Glutamine and Glutamate to Support Recurrent Monitoring of Acute Neonatal Hyperammonemia1R43HD094507-01SINGH, RAJENDRABAEBIES, INC., NC$231,134ZRG1
2018VR Grip Hand Peripheral for Improved Resident Training in Surgical Simulations1R43GM126719-01MARTIN, MICHAEL WILLIAMLYNNTECH, INC., TX$230,987ZRG1
2018Next Generation All Solid State NASS Lithium Batteries for Implantable Devices1R43HL140891-01LI, XUGUANGLYNNTECH, INC., TX$228,773ZRG1
2018Pan-HIV Incidence Assay Development1R43AI136196-01CAMERINI, DAVIDIMMPORT THERAPEUTICS, INC., CA$225,707ZRG1
2018Rapid Baseline Free Organophosphate Exposure Diagnostic Test1R43NS102080-01A1BASINGER, BILLCOUNTERVAIL CORPORATION, NC$225,225ZRG1
2018New Biotechnology using MicroRNA Inhibitors to Regenerate Alveolar Bone1R43DE027569-01SANDRA, ALEXANDERNATUREMIRI, LLC, IA$225,000ZRG1
2018An Acoustofluidic Device for Biocompatible Platelet Separation1R43HL140800-01WANG, LINASCENT BIO-NANO TECHNOLOGIES, INC., NC$225,000ZRG1
2018Development of an alpha-conotoxin RgIA analog as a novel, non-opioid therapeutic for chronic neuropathic pain1R43DA045413-01MERCADO, JOSE LKINETA, INC., WA$225,000ZRG1
2018A novel nutraceutical drug for tendinopathy treatment1R43AT009414-01A1LEONG, DANIEL JSUN, HUI BINNEW YORK/R&D/CTR/TRANSLATIONAL MED/THER, NY$225,000ZRG1
2018Activating latent growth factors for cartilage regeneration1R43AG058311-01LIU, YONGXING "JAMES"INNOVATIVE ELEMENTS, LLC, NJ$225,000ZRG1
2018A wearable device to detect opioid overdose and to prevent death1R43DA045407-01FARID-MOAYER, MEHRANBIORESP TECHNOLOGIES, INC., CA$225,000ZRG1
2018Universal Influenza Vaccine1R43AI136291-01LOCHER, CHRISTOPHERVERSATOPE THERAPEUTICS, INC., MA$225,000ZRG1
2018High-definition, wide field of view corneal imaging1R43EY028827-01CANAVESI, CRISTINALIGHTOPTECH CORPORATION, NY$225,000ZRG1
2018A high throughput next generation sequencing (NGS) pipeline to generate high quality recombinant therapeutic antibodies1R43CA224843-01BRADBURY, ANDREWSPECIFICA, INC., NM$225,000ZRG1
2018Off-the-Shelf Patch for Repairing Tracheal Stenosis1R43HL140890-01JOHNSON, JED KIZERNANOFIBER SOLUTIONS, LLC, OH$225,000ZRG1
2018High Density Array Digital PCR for Cancer Rare Mutation Quantification1R43CA221597-01A1HUNG, PAUL JU-SUNGCOMBINATI, INC., CA$225,000ZRG1
2018Development of a cell based assay to assess antigen specific tolerance1R43AI136484-01BERRY, SCOTT MMULLINS, BRIANNASALUS DISCOVERY, LLC, WI$225,000ZRG1
2018Real-time monitoring of inorganic chloramines near swimming pools1R43CK000544-01COWART, JOHNSEACOAST SCIENCE, INC., CA$225,000ZRG1
2018HeartMapp: A Closed-Loop Assessment and Treatment Mobile Application for Heart Failure1R43NR018415-01VANVLEET, THOMASPOSIT SCIENCE CORPORATION, CA$225,000ZRG1
2018A Sensor-based Platform for Hand Hygiene Tracking and Analysis1R43NR017372-01A1LIU, PENG PAULMICROSENSOR LABS, LLC, IL$225,000ZRG1
2018Exploiting activation-induced cell death as a means of inducing tolerance to kidney allografts1R43AI136151-01REDFIELD, ROBERT RAYYOLCU, ESMA SFASCURE THERAPEUTICS, LLC, KY$224,999ZRG1
2018Novel Immunotherapies for Comorbidity of Clostridium difficile and Inflammatory Bowel Disease1R43AI136108-01YANG, ZHIYONGFZATA, INC., MD$224,999ZRG1
2018Development of a hybrid transcatheter mitral valve replacement and repair device1R44HL140835-01PHAM, THUY MSUTRA MEDICAL, INC., CA$224,997ZRG1
2018A system to detect fall occurrence and location in hospital settings1R43AG056224-01CLARK, BRIAN RPARKER, B EUGENEBARRON ASSOCIATES, INC., VA$224,994ZRG1
2018Fast, flexible, and economical system for affinity-tag protein purification and tag removal1R43GM126676-01BRYAN, PHILIP NPOTOMAC AFFINITY PROTEINS, LLC, MD$224,994ZRG1
2018Scriptmate: A patient-centered mobile system for geriatric prescription medication management1R43AG057319-01HO, Y. XIANJACKSON, JONATHAN LEEDIMAGI, INC., MA$224,991ZRG1
2018Novel therapy for atopic dermatitis1R43AI136181-01LARRICK, JAMES WYU, BOLARIX BIOSCIENCE, LLC, CA$224,981ZRG1
2018Cerberus therapy for metastatic disease1R43CA217408-01A1MARTINEZ HACKERT, ERIK MATTHIASMESSMER, DAVORKATALAPO THERAPEUTICS, INC., CA$224,980ZRG1
2018Development of a unified information-rich test for CNBP and DMPK to improve assessment of Myotonic Dystrophy Type 1 and 21R43NS105463-01HALL, BRADLEYASURAGEN, INC., TX$224,978ZRG1
2018Synthetic hydrogels for biomanufacturing of iPSC-derived neural cells for precision medicine1R43NS102088-01A1LEBAKKEN, CONNIE SSTEM PHARM, INC., WI$224,976ZRG1
2018mHealth for Patient Self-Management of Opioid Use Disorder1R43MH119672-01BOWDEN, CHARLES LEEBIOMEDICAL DEVELOPMENT CORPORATION, KY$224,959ZRG1
2018Automatic Phrenic Nerve Stimulation to Rescue Opioid Induced Respiratory Depression1R43DA045442-01LEVIN, HOWARD DCORIDEA, LLC, NY$224,959ZRG1
2018Improved RSV F Vaccine Candidates1R43AI122411-01A1TOBIN, GREGORY JOHNBIOLOGICAL MIMETICS, INC., MD$224,956ZRG1
2018Synthetic biology E. coli strain development for expression of functional human GPCRs with roles in human disease1R43GM126828-01XU, KAREN D.PRIMROSE BIO, INC., CA$224,952ZRG1
2018HLS-Development of a cardiac ischemia model in an organ-on-a-chip platform1R43HL140920-01HICKMAN, JAMES JSHULER, MICHAEL LHESPEROS, LLC, FL$224,946ZRG1
20183D Imaging Flow Cytometer1R43DA045460-01CHO, SUNG HWANLO, YU-HWANANOCELLECT BIOMEDICAL, INC., CA$224,935ZRG1
2018Rapid and Efficient Extraction of Bacteria from Whole Blood for Sepsis Diagnosis1R43AI132072-01A1GATES, ELISABETHPRECISION MEMBRANES, LLC, UT$224,925ZRG1
2018Improving Anticoagulation Monitoring in Pediatric Patients: Use of a Microfluidic Platform to Test Low Volume Blood Samples Obtained by Heel-Stick Collection1R44HL140662-01PAMULA, VAMSEE K.BAEBIES, INC., NC$224,903ZRG1
2018A Resonator for Pulsed ODNP Spectroscopy to Study Surface Hydration Dynamics1R43GM126770-01MALY, THORSTENBRIDGE 12 TECHNOLOGIES, INC., MA$224,889ZRG1
2018Online course to prepare promotores to support low-income Latino parents of children with special healthcare needs1R44MD012412-01TWOMBLY, ERIC CHARLESKDH RESEARCH AND COMMUNICATION, INC., GA$224,828ZRG1
2018Device for Rapid, Complete & Durable Occlusion of Wide-Neck Cerebral Aneurysms1R43NS092184-01A1FRANANO, F. NICHOLASLOREE, HOWARD MARTINARTIO MEDICAL, INC., KS$224,818ZRG1
2018A Sensitive and Selective Microfluidic Nitrite Sensor1R43GM126768-01MCDUNN, JONATHAN EDWARDCLINICAL SENSORS, INC., NC$224,805ZRG1
2018The Home Evaluation, Assessment, Rating and Training of Gait (HEART-Gait) System for Monitoring Toe-Walking Severity in Children with Cerebral Palsy1R43LM013104-01BAMBERG, STACY J. MORRISVERISTRIDE, INC., UT$224,740ZRG1
2018Development of Non-Stigmatizing Hip Protection for Prevention of Fall-Related Injuries1R43AG054265-01A1CACCESE, VINCENTCASTLE, STEVENFERGUSON, JAMES RIDDELLALBA-TECHNIC, LLC, ME$224,682ZRG1
2018Neural Modulation System for In-Home Treatment of Overactive Bladder1R43AG058272-01BURNETT, DANIEL ROGERSTHERANOVA, LLC, CA$224,534ZRG1
2018Development of modified human thioredoxin as an inhaled biologic therapeutic for cystic fibrosis1R44HL140735-01HEIFETZ, PETER BORPRO THERAPEUTICS, INC., CA$224,482ZRG1
2018Mulitplexed detector array for VOC biomarker development1R43ES029032-01SAVOY, STEVE MICHAELNANOHMICS, INC., TX$224,325ZRG1
2018io-Balance assessment of balance control and fall risk1R43AG057281-01REEVES, NORMAN PETERSUMAQ LIFE, LLC, MI$224,132ZRG1
2018HEART: Adding Memory to Reasoning: macHine lEArning tailoRed drug Titration1R43HL140624-01VOSKERICIAN, GABRIELAOPTIMA INTEGRATED HEALTH, INC., CA$224,090ZRG1
2018Oxygen-Generating Dressing1R43NR017127-01A1CARTER, ANDYTHERACELL, INC., CA$223,730ZRG1
2018FoxWare™, An Advanced Data Analysis Package for Hydroxyl Radical Foot-Printing Higher Order Structural Analysis1R43GM126617-01WEINBERGER, SCOT RANDYGENNEXT TECHNOLOGIES, INC., CA$223,704ZRG1
2018Using Augmented Reality To Make Cardiac Ablation Procedures Simpler and Safer1R44HL140896-01BLUME, WALTERSILVA, JENNIFER NSILVA, JONATHAN RSENTIAR, INC., MO$223,532ZRG1
2018Omniphobic Coating to Prevent Central Line Catheter Infections1R43AI136573-01JONES, ANDREW KCERULEAN SCIENTIFIC INC., PA$222,842ZRG1
2018Head mounted smartphone system for remote treatment of convergence insufficiency1R43EY028778-01HOUSTON, KEVIN EDWARDLUO, GANGTOMASI, MATTEOEYENEXO LLC, MA$219,444ZRG1
2018Enhanced x-ray angiography analysis and interpretation using deep learning1R43HL140794-01HENAO GIRALDO, RICARDOPATEL, MANESH RVENKATESHA, SANTOSHVIGILANT MEDICAL, INC., MD$217,746ZRG1
2018GreenCare Interactive Guide for Knee Replacement Surgery1R43AG055219-01A1MIRZA, SOHAIL KPEER TECHNOLOGIES, PLLC, DC$217,597ZRG1
2018Feasibility and validation of an integrated newborn screening algorithm with the targeted Next Generation Sequencing (tNGS) technology as part of a 2nd tier test for Pompe and MPS I1R43HD094543-01BHATTACHARJEE, ARINDAMBAEBIES, INC., NC$215,022ZRG1
2018SiPM Array detector for 50 ps CTR1R43MH115637-01HARMON, ERIC SLIGHTSPIN TECHNOLOGIES, INC., NY$213,938ZRG1
2018Prehospital and Emergency Room Stroke Diagnosis Using Quantitative Cerebral Hemodynamics1R43NS105340-01THIBEAULT, COREY MICHAELNEURAL ANALYTICS, INC., CA$213,206ZRG1
2018Minimizing bloodstream infection detection time using laser light-scattering1R43AI136184-01TOMARAS, ANDREW PBACTERIOSCAN, INC., MO$210,937ZRG1
2018Adaptive Web-based Software for Enhancing Social Communication Skills in Youth with Autism Spectrum Disorder to Facilitate Employment Success1R43DC016769-01CHILDRESS, DEBRA3-C INSTITUTE FOR SOCIAL DEVELOPMENT, NC$209,696ZRG1
2018A Tailored Approach to Promoting Engagement in Public Health1R44NR016908-01A1HIRSHFIELD, SABINATAN, WILLIAM ZTRANSCENDENT INTERNATIONAL, LLC, NY$207,995ZRG1
2018Calpain Therapeutics to Inhibit Myofibroblast Generation in Fibrosis1R43HL140829-01GREENBAUM, DORONPHELIX THERAPEUTICS, LLC, PA$201,665ZRG1
2018Unified Process for the Discovery of Protein Biomarkers and their X-Aptamer Affinity Reagents1R43GM126604-01YANG, XIANBINAM BIOTECHNOLOGIES, LLC, TX$185,564ZRG1
2018Next Generation Testing Strategies for Assessment of Genotoxicity1R44ES029014-01BEMIS, JEFFREY CDERTINGER, STEPHEN DLITRON LABORATORIES, LTD., NY$178,854ZRG1
2018Rapid automated polarizable multipole-based force field parameterization for accurate drug-receptor binding affinity calculations.1R43GM126579-01HO, CHRIS MDRUG DESIGN METHODOLOGIES, LLC, MO$175,994ZRG1
2018Validation of Cross-Species Biomarkers of DNA Damage1R44ES028163-01A1BEMIS, JEFFREY CDERTINGER, STEPHEN DLITRON LABORATORIES, LTD., NY$172,660ZRG1
2018A Serological Assay for Neutralizing Antitoxin Response in Patients with Clostridium difficile Infection1R43AI136176-01YANG, ZHIYONGFZATA, INC., MD$168,931ZRG1
2018A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells1R43HG010025-01MCCONNELL, TIMOTHY SZHENG, RUIISOPLEXIS, INC., DE$163,731ZRG1
2018A Customizable Real-Time Biosensor for Continuous Monitoring of Water Contaminants1R43ES028993-01COOKSON, SCOTT WARRENQUANTITATIVE BIOSCIENCES, INC., CA$162,205ZRG1
2018Multifunctional Antioxidant to Prevent Noise-Induced Hearing Loss1R43DC016766-01KADOR, PETER FTHERAPEUTIC VISION, INC., NE$150,000ZRG1
2018RECAL®: A New Tool for Disease Detection and Biomolecular Imaging1R43GM126577-01BORDERS, BRYAN CLARKEPHOTON BIOSCIENCES, LLC, WA$150,000ZRG1
2018HLS- SBIR Phase I: Development of a robust, color-based, disposable, standalone anemia test for low-resource settings1R43HL139250-01A1LAM, WILBUR ASTRIBLING, THOMAS SLIGHSANGUINA, LLC, GA$150,000ZRG1
2018Miniaturized Global Coagulation Assay System in Neonatal and Pediatric Settings1R43HL140686-01KOLANDAIVELU, KUMARANZHAO, XINATANTARES CORPORATION, MA$150,000ZRG1
2018New Techniques for Real-Time Microsleep Assessment1R43DP006416-01LANDAU, ALEXANDERVERIFAX CORPORATION, CO$150,000ZRG1
2018Polyketide chiral building blocks and biocatalysts1R43GM126594-01GAY, DARREN CHRISTIANKEATINGE-CLAY, ADRIAN TRISTANCOALA BIOSCIENCES, TX$149,999ZRG1
2018Development of a Human Liver Microphysiological System For Alcoholic Liver Disease1R43AA026473-01BARREIROS PETROPOLIS, DEBORAKARALIS, KATIAEMULATE, INC., MA$149,996ZRG1
2018Medical Device Cyber-Security1R43GM126614-01UPLINGER, JAMESNOKOMIS, INC., PA$149,782ZRG1
2018Deep Learning to Transform Clinician Autism Diagnostic Assessments and More1R44MH115523-01OBERLEITNER, RONALDCARING TECHNOLOGIES, INC., ID$149,124ZRG1
2018In situ assay for RNA decapping in tumors1R43CA221560-01WANG, SHAVIVID TECHNOLOGIES, TX$149,051ZRG1
2018An integrated mobile and web-based application for problem cannabis use1R43DA045390-01CAMPBELL, WILLIAM PCHECKUP AND CHOICES, LLC, NM$148,980ZRG1
2018Integrated System for Rapid Production of Activated Sugars and Glycosylated Molecules1R43GM126672-01AMINOVA, LEILAZUCHEM, INC., IL$147,325ZRG1
2018A Low-Cost Platform for Routine High-Accuracy Sizing of Nucleic Acid Samples with 100 bp - 100 Mbp Dynamic Range1R44HG009993-01MENARD, LAURENTGENTURI, INC., MA$146,126ZRG1
2018Development of a syringe/sonication device employed to administer DDFPe in the prehospital setting1R43NS105295-01UNGER, EVAN CHARLESNUVOX PHARMA, LLC, AZ$143,988ZRG1
2018Powerful Solid-State Sources to Enable Advanced EPR and DNP-NMR Measurements1R43GM126771-01BRYERTON, ERICVIRGINIA DIODES, INC., VA$138,047ZRG1
2018Universal Liquid Chromatography Detector Utilizing Reactive Flame Ionization Detection1R43GM126591-01JONES, ANDREW JAMESACTIVATED RESEARCH COMPANY, LLC, MN$78,518ZRG1
2017TempO-Seq Gene Expression Profiling of Intracellular Stained FACS Sorted Cells2R44HG008917-02A1SELIGMANN, BRUCE E.BIOSPYDER TECHNOLOGIES, INC., CA$1,923,939ZRG1
2017Long-acting PTH for hypoparathyroidism2R44DK107231-02A1HALES, LAURA MEXTEND BIOSCIENCES, INC., MA$1,802,798ZRG1
2017Biased Agonism In GPCR Drug Discovery: Application To Somatostatin Agonists2R44DK088501-04A1STRUTHERS, RICHARD SCOTTCRINETICS PHARMACEUTICALS, INC., CA$1,448,103ZRG1
2017Novel treatment of posttraumatic stress disorder2R44MH103936-03LAI, YVONNE Y.ANAGIN, IN$1,373,142ZRG1
2017Enzyme replacement therapy for GM1 gangliosidosis lysosomal rare disease2R44NS084565-02 · under PA-15-269ACOSTA, WALTERCRAMER, CAROLE L.D'AZZO, ALESSANDRARADIN, DAVIDBIOSTRATEGIES, LC, AR$1,366,586ZRG1
2017Unpinning Termination Therapy for Ventricular Tachyarrhythmias2R44HL107055-02COOPER, DANIEL HEFIMOV, IGOR RSHELTON, MICHAEL BRENTCARDIALEN, INC., MO$1,351,728ZRG1
2017TempO-Seq: A Multiplexed Gene Expression Profiling Platform2R44HG007339-03 · under PA-15-269YEAKLEY, JOANNE MULLIGANBIOSPYDER TECHNOLOGIES, INC., CA$1,258,482ZRG1
2017Tumor-Specific Fluorescent Cocktail Enables Image-Guided Cytoreductive Surgery2R44CA192569-02KULARATNE, SUMITHON TARGET LABORATORIES, LLC, IL$1,250,146ZRG1
2017Improving MPS I ERT Efficacy through Lectin-Mediated Delivery1R44NS102086-01ACOSTA, WALTERCRAMER, CAROLE L.RADIN, DAVIDBIOSTRATEGIES, LC, AR$1,237,037ZRG1
2017Nonclinical development of Nervelight, an intra-operative peripheral nerve imaging agent2R44CA180745-02KAHL, STEPHEN BMANZANITA PHARMACEUTICALS, INC., CA$1,220,153ZRG1
2017An optimized NK2R agonist for 'on-demand' voiding2R44AG055169-02THOR, KARL BDIGNIFY THERAPEUTICS, LLC, NC$1,158,181ZRG1
2017Targeted Therapy for Non Small Cell Lung Carcinoma: Human Phase 1 safety and dose escalation studies2R44CA162629-02A1SERRERO, GINETTEA AND G PHARMACEUTICAL, INC., MD$1,154,726ZRG1
2017Safety and Efficacy Testing of FX101 in an SIV/NHP Model2R44MH096663-03A1 · under PA-15-269BOLTON, DIANE L.KAY, HEIDI ARAPPAPORT, JAYJERICHO SCIENCES, LLC, VA$1,154,643ZRG1
2017Digital serology panel for multiplex tick-borne disease testing2R44GM119873-02DAUGHERTY, PATRICK SSERIMMUNE, INC., CA$1,146,287ZRG1
2017Novel Bone-Targeting Combination Therapy for Osteosarcoma Phase II2R44CA203166-02ZINNEN, SHAWN PATRICKMBC PHARMA, INC., CO$1,138,475ZRG1
2017Higher Order Structure Analysis of Protein Therapeutics by Covalent Labeling MS2R44GM116211-02GRABAN, ERICRECLAIM PHARMACEUTICAL WASTE MANAGEMENT, FL$1,100,964ZRG1
2017Improving safety and efficacy of platelet transfusion through systems biology2R44HL127843-02BORDBAR, AARASHSINOPIA BIOSCIENCES, INC., CA$1,099,022ZRG1
2017Practical high resolution microscopy of un-cut, un-embedded lung biopsies2R44CA189522-02LEVENE, MICHAEL JOHNTORRES, RICHARDAPPLIKATE TECHNOLOGIES, INC., CT$1,091,279ZRG1
2017Development of a mobile and automated platform for multiplexed multi-modality imaging2R44CA192482-02A1GESSNER, RYANSONOVOL, INC., NC$1,083,219ZRG1
2017Point of Care Breath Test to Screen for Sickle Cell Disease in Developing Nations2R44HL126469-02A1BHATNAGAR, ANISHSOLENO THERAPEUTICS, INC., CA$1,057,282ZRG1
2017Development of PAR2 Pepducins as a Novel NASH Treatment2R44DK101240-04A1KULIOPULOS, ATHANOASIS PHARMACEUTICALS, MA$1,048,644ZRG1
2017Suppressors of kRAS Activity Discovered Using a Fruit Fly-based In-vivo Screen2R44CA189549-02A1GARLAND, WILLIAM A.THOMAS, JEFFREY HTOSK, INC., CA$1,043,722ZRG1
2017A novel immunotolerizing therapy for autoimmune vitiligo2R44AR065886-02A1MURTHY, KANNEGANTIRADIKAL THERAPEUTICS, INC., MA$1,039,086ZRG1
2017Phase II: Research and Commercialization of TruT Algorithm for Free Testosterone2R44AG045011-02JASUJA, RAVIFUNCTION PROMOTING THERAPIES, LLC, MA$1,029,716ZRG1
2017Novel targeted Chemotherapeutics for Gliobastoma2R44CA174129-02A1KOLLER, KERRY JEANQUADRIGA BIOSCIENCES, INC., CA$1,018,590ZRG1
2017FrostBite - A Unique Catheter for Endoscopic Cryoablation2R44CA183265-02A1BAUST, JOHN MCELL PRESERVATION SERVICES, INC., NY$1,008,442ZRG1
2017A sample-to-answer diagnostic for neonatal bloodstream infections2R44HD083971-02SINGER, ALONHELIXBIND, INC., MA$1,003,051ZRG1
2017A Novel Peptide Therapeutic for Obesity2R44DK101197-02FANGER, NEIL AVIRTICI, LLC, WA$1,000,985ZRG1
2017Commercialization of an MRI contrast agent for differential diagnosis of prostate cancer.2R44CA199826-02A1LI, YAJUANMOLECULAR THERANOSTICS, LLC, OH$1,000,342ZRG1
2017Production Technology for Recombinant Intravenous Immunoglobulin2R44AI115892-02A1 · under PA-15-269JOHNSON, DAVID SCOTTGIGAGEN, INC., CA$1,000,000ZRG1

Showing the 200 most recent of 2,800 awards.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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