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NIH funding notice PA-17-302

PHS 2017-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Closed on January 5, 2018.

Posted
June 5, 2017
Close date
January 5, 2018
Activity codes
R43, R44
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP, CGH, NCBDDD, NCCDPHP, NCEZID, NCHHSTP, NCIRD, NCIPC, NIOSH, OPHPR, NCEH, CBER, CDER, CFSAN, CDRH, CVM, CPI, OOPD

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-16-302 PHS 2016-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  2. 2 steps back: PA-15-269 PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  3. 3 steps back: PA-14-071 PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  4. 4 steps back: PA-13-234 Reissue PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  5. 5 steps back: PA-13-088 PHS 2013-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  6. 6 steps back: PA-12-088 PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  7. 7 steps back: PA-11-096 PHS 2011-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  8. 8 steps back: PA-10-050 PHS 2010-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
  9. 9 steps back: PA-09-080 PHS 2009-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Replaced by PA-18-574.

Who won it before

3,426 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $1,225,480,156 in first-year total cost, median $225,000.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-G (12)]176
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]168
  3. Special Emphasis Panel[ZRG1 ETTN-M (11)]124
  4. Special Emphasis Panel[ZRG1 RPHB-C (10)]115
  5. Special Emphasis Panel[ZRG1 IDM-V (12)]112

Most frequent institutions

  1. AFFINERGY, LLC22
  2. PANORAMA RESEARCH, INC.22
  3. PHYSICAL SCIENCES, INC22
  4. EPICYPHER, INC.18
  5. PROGENRA, INC.18
Competing awards under PA-17-302 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Completion of IND-package for a novel, non-narcotic painkiller2R44DA041912-03YEKKIRALA, AJAY SBLUE THERAPEUTICS, INC., MA$1,474,091ZRG1
2019Radiation Sterilizable, RFID Tagged Vials for Biomedical Samples2R44OD020162-04DAVIDOWITZ, HANANELBIO TILLION, LLC, NJ$999,504ZRG1
2019Measuring toxicant effects on cellular function in a microarray format2R42ES026245-02A1GUIGNON, ERNEST FITCHLYNES, MICHAEL ACIENCIA, INC., CT$500,000ZRG1
2019STING Inhibitor Discovery for Rare and Common Autoimmune Diseases1R43AI141819-01BANTIA, SHANTASCHWIEBERT, ERIK MILLSSTREIFF, JOHN HDISCOVERYBIOMED, INC., AL$300,000ZRG1
2019Developing a High-throughput Bioprinting Platform for 3D iPSC-derived Liver Tissues for Early Drug Screening1R43EB026411-01A1ZHU, WEIALLEGRO 3D, INC., CA$299,281ZRG1
2019Development of a fixed-dose combination therapy for the treatment of chronic musculoskeletal pain1R43AR074369-01TOCZKO, MATTHEW ALEXANDERNEUROCYCLE THERAPEUTICS, INC., MA$225,531ZRG1
2019Using Virtual Reality Psychological Therapy to Develop a Non-Opioid Chronic Pain Therapy1R43NR017575-01A1BAEUERLE, TASSILOCEKO, MARTAWEBSTER, LYNNCOGNIFISENSE, INC., CA$225,000ZRG1
2019Material-guided delivery and local activation of bioorthogonal prodrugs1R44GM130240-01MEJIA ONETO, JOSE MTAMBO, INC., CA$216,910ZRG1
2019Online System for Primary Care to Prevent and Address Teen Substance Use1R44DA046262-01HARRIS, SION KIMHOWARD, BARBARA JOSTURNER, RAYMONDTOTAL CHILD HEALTH, INC., MD$209,799ZRG1
2019A Phase 1 Randomized Single Oral Dose Four Period Cross-Over Study Investigating Omnitram Dose Proportionality and Food Effect in Normal Human Subjects1R44DA046316-01A1KAHN, STUART JZEBALA, JOHN ASYNTRIX BIOSYSTEMS, INC., WA$204,489ZRG1
2019Screening Device for Autism Spectrum Disorders using High Stimulation Rate ABR with Continuous Loop Averaging Deconvolution1R43DC018430-01DELGADO, RAFAEL EINTELLIGENT HEARING SYSTEMS, FL$200,092ZRG1
2019Quantitative Methane Plume Imager for Localization and Flow Rate Estimation in Mines1R43OH011711-01CHEN, SHIN-JUHPHYSICAL SCIENCES, INC, MA$149,999ZRG1
2018Commercialization of HaploSeq as a Service (HaaS) for generating chromosome-span phased genome and exome sequence information2R44HG008118-04A1 · under PA-16-302DIXON, JESSE RLAURENT, LOUISE CHANGSELVARAJ, SIDDARTHARIMA GENOMICS, INC., CA$1,573,140ZRG1
2018Peripherally-restricted and long-acting kappa-opioid receptor (LA-KOR) agonists for pain2R44DA042634-02RIVIERE, PIERREPEPTIDE LOGIC, LLC, CA$1,524,027ZRG1
2018Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction2R44NS098885-02FLORIO, STEPHANIE KANAGIN, IN$1,498,044ZRG1
2018Device for Treatment of Cardiac No-Option Patients2R44HL129586-02HUBBARD, TERRYKASSAB, GHASSAN SWANG, MENGJUN3DT HOLDINGS, LLC, CA$1,432,551ZRG1
2018Automation and validation of human on a chip systems for drug discovery2R44TR001326-03HICKMAN, JAMES JSHULER, MICHAEL LHESPEROS, LLC, FL$1,363,424ZRG1
2018Small Molecule Treatments to Enhance Neurological Recovery After Stroke2R44NS095381-02 · under PA-16-302FINKLESTEIN, SETH PSTEMETIX, INC., MA$1,354,461ZRG1
2018HBI-002 to Prevent Vaso-Occlusive Crises in Sickle Cell Disease2R44HL131065-03A1BELCHER, JOHN DGOMPERTS, EDWARDHILLHURST BIOPHARMACEUTICALS, INC., CA$1,270,298ZRG1
2018An add-on microscopy module for fast volumetric imaging2R44MH111463-02A1LINNENBERGER, ANNAMEADOWLARK OPTICS, INC., CO$1,258,442ZRG1
2018Development of a Yellow Fever Vaccine for a Vulnerable Population2R44AI079898-06 · under PA-16-302AMANNA, IAN JAMESSLIFKA, MARK KNAJIT TECHNOLOGIES, INC., OR$1,248,114ZRG1
2018Novel 5-HT7 Antagonists for the treatment of inflammatory bowel disease2R44DK115254-02A1BLASS, BENJAMINCANNEY, DANIEL JPIPPIN, DOUGLAS ANTHONYPRAEVENTIX, LLC, PA$1,228,145ZRG1
2018Multiplexed high-content assay for toxicity profiling using live iPSC-derived cardiomyocyte lines with lineage-specific barcoding2R44TR002572-02LUDLAM, MARYCAIRN BIOSCIENCES, INC., CA$1,178,386ZRG1
2018Micro-imaging catheters for high-resolution, image-guided, endovascular repair of brain aneurysms2R44NS100163-02UGHI, GIOVANNI J.GENTUITY, LLC, MA$1,168,051ZRG1
2018EVVS: Endoscopic Venous Valve System2R44HL137540-02A1GALTES, JANETVENARUM MEDICAL, LLC, NJ$1,165,363ZRG1
2018Accelerated discovery of methylation targeted therapeutic development2R44CA212733-02SUN, ZU-WENEPICYPHER, INC., NC$1,148,788ZRG1
2018Wearable Vibration Device to Prevent Bone Loss in Postmenopausal Women2R44AG046005-02 · under PA-16-302BILEK, LAURA DIANEBURNETT, DANIEL ROGERSTHERANOVA, LLC, CA$1,146,609ZRG1
2018Device for rapid extraction of rare pathogens from raw samples2R44AI124930-02 · under PA-16-302FISHER, JAY KENNETHREDBUD LABS, INC., NC$1,140,832ZRG1
2018Clinical Evaluation of a New Middle Ear Diagnostic to Support FDA Regulatory Clearance2R44DC014599-03SHELTON, RYAN LPHOTONICARE, INC., IL$1,126,043ZRG1
2018A Circulating Biomarker for use in Monitoring Metastatic Breast Cancer2R44CA210817-02SERRERO, GINETTEA AND G PHARMACEUTICAL, INC., MD$1,101,350ZRG1
2018A Device for Measuring Blood Concentrations of Unbound Bilirubin in Neonates2R44HD080412-04A1KLEINFELD, ALAN MARCFLUORESPROBE SCIENCES, LLC, CA$1,047,363ZRG1
2018Ambient light activatable opsin based therapy for age-related macular degeneration2R44EY025905-02A1MOHANTY, SAMARENDRA KUMARWRIGHT, WELDONNANOSCOPE TECHNOLOGIES, LLC, TX$1,031,182ZRG1
2018Sleeping Beauty Engineered B Cells for Mucopolysaccharidosis2R44GM115192-02A1HAMPE, CHRISTIANE SIMMUSOFT CORPORATION, WA$1,028,903ZRG1
2018A Novel Test to Measure Latent Virus in HIV-1 Infected Patients2R44AI124996-02 · under PA-16-302LAIRD, GREGORY MICHAELACCELEVIR DIAGNOSTICS, LLC, MD$1,000,000ZRG1
2018Novel Combination Product with Activity Against MRSA, MDR-Enterics and Pseudomonas2R44AI120392-03A1BURNS, CHRISTOPHER JOHNVENATORX PHARMACEUTICALS, INC., PA$1,000,000ZRG1
2018sHLA Protein Chip2R44AI122642-03JAYARAMAN, KRISHNAGENOMICS USA, INC., TX$1,000,000ZRG1
2018Antibody targeting of ADAM8 for treatment of triple-negative breast cancer2R44CA200161-02A1SONENSHEIN, GAIL E.ADECTO PHARMACEUTICALS, INC., MA$1,000,000ZRG1
2018Improved cleaning technology for reducing risk of transmitting infection in endoscopy.2R44AI132040-02LABIB, MOHAMED ESOHN, SEO YEANADVANCED BIODEVICES, LLC, NJ$999,998ZRG1
2018A Prognostic Blood Test to Monitor Pancreatic Cancer Treatment by MiRNA Profiling2R44CA199058-02SARAF, RAVIVAJRA INSTRUMENTS, INC., NE$999,597ZRG1
2018Development of a novel therapeutic for the treatment of diabetic nephropathy and renal fibrosis2R44DK092005-04SHARMA, KUMARTUCCI, FABIO COHENEPIGEN BIOSCIENCES, INC., CA$999,500ZRG1
2018Preclinical development of teixobactin, a new antibiotic2R44AI118000-03HUGHES, DALLASNOVOBIOTIC PHARMACEUTICALS, LLC, MA$999,040ZRG1
2018Development of a kit for the targeted depletion of abundant sequencesfromDNA/RNA libraries2R44AI124933-03 · under PA-16-302CARPENTER, MEREDITH LAURENARC BIO, LLC, MA$998,921ZRG1
2018Integrating CNV analysis into a NextGen sequencing clinical analytics platform2R44GM125432-02SCHERER, ANDREASGOLDEN HELIX, INC., MT$997,214ZRG1
2018Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimer's Disease2R44AG051282-03SMITH, JENNIFER JOYPRECYTE, INC., MD$996,801ZRG1
2018Optimization and Validation of an indicator cell assay for blood-based diagnosis of lung cancer2R44CA203455-02A1SMITH, JENNIFER JOYPRECYTE, INC., MD$996,232ZRG1
2018Phase IIB - Smart Eyewear Assistant for the Support of Seniors and their Caregivers in the Long-term Care Setting2R44AG046969-04FAUCI, MARK AGEN-9, INC., CA$995,645ZRG1
2018Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine2R44AI114331-02A1 · under PA-16-302BAGLEY, KENNETH CPROFECTUS BIOSCIENCES, INC., MD$993,161ZRG1
2018Evaluating the impact of novel inhibitors of nuclear pore export in SLE2R44AI124949-02 · under PA-16-302LANDESMAN, YOSEFTAMIR, SHARONKARYOPHARM THERAPEUTICS, INC., MA$992,511ZRG1
2018Development of Molecular Diagnostic Test for Early Onset of Lyme disease2R44AI114009-02 · under PA-16-302SCHUTZER, STEVEN EBIOSCIENCE DEVELOPMENT, INC., NY$988,413ZRG1
2018Modeling Disease in Swine by Transplantation of Gene Targeted Germ Cells2R44GM108150-02A1CARLSON, DANIEL FREDRECOMBINETICS, INC., MN$986,749ZRG1
2018Aerosol Delivery of Surfactant for ARDS2R44HL127834-02A1 · under PA-16-302YEATES, DONOVAN BYRONKAER BIOTHERAPEUTICS CORPORATION, CA$986,436ZRG1
2018Interstitial Intensity Modulated Photodynamic Therapy Phase II2R44CA213654-02POTASEK, MARYSHAFIRSTEIN, GALSIMPHOTEK, INC., NJ$984,904ZRG1
2018NAAA Inhibition for Pain and Inflammation2R44NS092123-02A1MONAGHAN, EDWARD PAULNEOKERA, LLC, MA$983,494ZRG1
2018IOBIO based, distributed genomic data access, management, visualization, and analysis2R44HG009096-02MARTH, GABOR TMILLER, CHASEWARD, ALISTAIRFRAMESHIFT LABS, INC., MA$982,303ZRG1
2018Modulation of the Innate Immune Response by Fisetin Derivatives for the Treatment of AD2R44AI104034-05A1RASCHKE, WILLIAM CVIROGENICS, INC., CA$977,956ZRG1
2018Preclinical Development of Oxy200 for the Treatment of Osteoporosis2R44AG055374-04STAPPENBECK, FRANKMAX BIOPHARMA, INC., CA$975,009ZRG1
2018Commercialization of a Software Platform to Increase the Efficiency of Human Clinical Trials using Patient-Level Machine Learning Models2R44TR002047-02ENNIST, DAVID LORIGENT DATA SCIENCES, INC., VA$969,314ZRG1
2018Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need2R44TR001912-02HENDERSON, WENDY AKIM, CHANG HEEGODX, INC., WI$966,680ZRG1
2018Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development2R44CA203090-02GAMBHIR, SANJIV SUNGER, EVAN CHARLESNUVOX PHARMA, LLC, AZ$963,578ZRG1
2018PDE4D PET Ligand2R44MH107077-02A1GURNEY, MARK ETETRA DISCOVERY PARTNERS, INC., MI$952,592ZRG1
2018Development of a Surgical Simulator for Endovascular Access Training2R44HL132665-02BEASLEY, RYAN ANDREWSIMQUEST INTERNATIONAL, LLC, MD$943,802ZRG1
2018Multiplexed Bead-based In Vitro Pediatric Allergy Test2R44AI100424-06 · under PA-16-302LIM, MARKAMBERGEN, INC, MA$937,987ZRG1
2018Automated assessment using facial coding2R44DA042640-02NAJAVITS, LISA MTREATMENT INNOVATIONS, LLC, MA$930,188ZRG1
2018TDP-43 aggregation inhibitors for the treatment of ALS2R44NS095481-03LARSEN, GLENNWOLOZIN, BENJAMIN LAQUINNAH PHARMACEUTICALS, INC., MA$923,960ZRG1
2018Development Of Novel Diabetes Therapies Based On Neutralizing FSTL3 Activity2R44DK107018-03A1SCHNEYER, ALAN LFAIRBANKS PHARMACEUTICALS, MA$920,248ZRG1
2018Real-time volumetric specimen imager for 3D intra-operative lumpectomy margin assessment2R44CA206801-02HAN, XIAOCLARIX IMAGING CORPORATION, IL$920,127ZRG1
2018Small Molecule Inhibitors of PCSK9-Phase II2R44HL134462-02FEIG, PETER USHAH, SALIMHINGEZ THERAPEUTICS, INC., VA$909,169ZRG1
2018High-throughput methyltransferase assays using recombinant nucleosome substrates2R44GM117683-02A1 · under PA-16-302SUN, ZU-WENEPICYPHER, INC., NC$903,808ZRG1
2018Therapeutic Development of RNAi-based inhibitors against the Hepatitis Delta Virus2R44AI104007-02A1JOHNSTON, BRIAN H.SOMAGENICS, INC., CA$902,942ZRG1
2018A preclinical multi-modal system for dynamic noninvasive assessment of liver disease2R44DK112492-02CZERNUSZEWICZ, TOMASZ JOSEPHGESSNER, RYANSONOVOL, INC., NC$896,265ZRG1
2018Tumor Embolization Using A Novel Catheter With Integrated Flow Regulation2R44CA192428-02A1ALLEN, MICHAEL PATRICKEMBOLX, INC., CA$893,847ZRG1
2018Spatial Genomics for in situ single cell expression analysis in the brain1R43MH115538-01A1FRIEDA, KIRSTENSPATIAL GENOMICS, INC., CA$885,468ZRG1
2018Development of a novel bioabsorbable clip and applier for rapid closure of the dura mater in open and minimally invasive spine surgery.2R44NS107104-02DREILINGER, RACHELNEURAMEDICA, LLC, OR$870,245ZRG1
2018A nucleosome sliding assay platform to screen inhibitors of SWI/SNF chromatin remodeling complexes2R44GM123869-02KEOGH, MICHAEL-CHRISTOPHEREPICYPHER, INC., NC$866,168ZRG1
2018Novel therapeutic approach in treatment of glioblastoma using sustained delivery of Connxin43 carboxy-terminal peptide encapsulated in biodegradable nanoparticles in combination with temozolomide2R44CA195937-02A1GREK, CHRISTINAXEQUEL BIO, INC., SC$841,361ZRG1
2018Novel genotoxicity assay incorporating the toxicogenomics biomarker TGx-28.65 with a direct digital counting2R44ES026473-02FORNACE, ALBERT JGEORGE, JAYAMELIA TECHNOLOGIES, LLC, DC$840,491ZRG1
2018Rapid Detection of Common Failure Modes for Knee Prosthetics2R44AR067048-02A1BILLI, FABRIZIOROSS, GRAHAMBRUIN BIOMETRICS, LLC, CA$839,554ZRG1
2018Development of a novel highly effective influenza vaccine2R44AI109925-03 · under PA-16-302BILSEL, PAMUKSARAWAR, SALLY R.FLUGEN, INC., WI$834,285ZRG1
2018Large Pore SPP Particles for Protein Separations2R44GM116224-02BOYES, BARRY EADVANCED MATERIALS TECHNOLOGY, INC., DE$833,309ZRG1
2018Targeted Polymerized Shell Microbubbles to Image and Treat Surgical Adhesions2R44GM116530-02NAGY, JON OWENWONG, JOYCE YNANOVALENT PHARMACEUTICALS, INC., MT$831,190ZRG1
2018Developing and Evaluating In-Home Supportive Technology for Dementia Caregivers1R44AG059458-01WANG, GENEPEOPLE POWER COMPANY, WA$825,561ZRG1
2018Cancer Imaging and Therapy Analysis Platform (CITAP)2R44CA213601-02GARGESHA, MADHUSUDHANAWILSON, DAVID LYNNBIOINVISION, INC., OH$817,362ZRG1
2018Microhook nerve tape: A nerve repair coaptation aid2R44NS097113-03A1CLEMENTS, ISAAC PERRYAXION BIOSYSTEMS, LLC, GA$810,116ZRG1
2018Responsive eHealth Intervention for Perinatal Depression in Healthcare Settings2R44MH109191-02DANAHER, BRIAN G.SEELEY, JOHN RSILVER, RICHARD KARLSMITH, DAVID RANDOLPHOREGON RES BEHAVIORAL INTERVENTION STRAT, OR$801,141ZRG1
2018Creating Physical Objects with 3D Printers to Stimulate Reminiscing for Memory Loss2R44AG049548-02A1PLOCHER, TOMMOAI TECHNOLOGIES, LLC, MN$799,785ZRG1
2018Lab-To-Marketplace: Commercialization of a stretchable microelectrode array2R44NS086118-03A1GRAUDEJUS, OLIVERBMSEED, LLC, AZ$796,856ZRG1
2018Improved Silicone Lubrication to Reduce Sub-Visible Particles in Parenteral Containers.2R44EY024461-02A1THORNTON, JACKSON DTRIBOFILM RESEARCH, INC., NC$796,770ZRG1
2018Transdermal H2S Sensing Device for Monitoring Peripheral Artery Disease2R44HL121871-02A1KANAGY, NANCY LSHEKARRIZ, REZAEXHALIX, LLC, NM$790,092ZRG1
2018A technology solution for peer-led Seeking Safety2R44DA041949-02NAJAVITS, LISA MTREATMENT INNOVATIONS, LLC, MA$789,598ZRG1
2018A Novel Glycosaminoglycan-Based Therapeutic for Chronic Rhinosinusitis2R44AI126987-02ALT, JEREMIAH ANDREWPULSIPHER, ABIGAILGLYCOMIRA, LLC, UT$781,547ZRG1
2018Intraoperative Ureter Detection System2R44HD089769-02SHUKAIR, SHETHABRITESEED, LLC, IL$780,962ZRG1
2018Miniaturized Stopped-Flow Reaction Microcalorimeter for Biomedical Applications2R44GM113279-02A1 · under PA-16-302BROWN, RICHARD KENNETHCAPE BIORESEARCH, INC., MA$775,488ZRG1
2018Over-the-Wire Device for Immediate and Complete Peripheral Artery Occlusion2R44HL124832-02A1 · under PA-16-302FRANANO, F. NICHOLASARTIO MEDICAL, INC., KS$765,897ZRG1
2018Tools for the site-specific labeling and immobilization of antibodies for immunoassays2R44EB023750-02YU, FEIFANALPHATHERA, INC., PA$764,390ZRG1
2018A smartphone-based point-of-care test for detection of Chlamydia trachomatis2R44AI118180-02PATERSON, ANDREW SLATORLUMINOSTICS, INC., CA$761,788ZRG1
2018Bactericidal Intravascular Biosensor for Continuous Reading of Lactate in the lCU Ph22R44GM119883-02CHEN, HAOBIOCREDE, INC., MI$760,088ZRG1
2018Developing the required biomarkers that define ferroportin target engagement and impact on downstream signaling for clinical translation2R44HL132702-02LIU, DAVID YPROTAGONIST THERAPEUTICS, INC., CA$758,874ZRG1
2018An implantable hemodialyzer for treatment of End-stage Renal Disease2R44DK102240-02BLAHA, CHARLESSILICON KIDNEY, LLC, CA$756,920ZRG1
2018Ophthalmic drug delivery using a multi-layer contact lens design that enables targeting, constant-rate release and failure protection2R44EY026850-02A1 · under PA-16-302YANG, ARTHURLYNTHERA CORPORATION, PA$754,785ZRG1
2018A Phase II trial of abiraterone in combination with PDMX1001 in enzalutamide-resistant prostate cancer2R44CA206668-02A1LIU, CHENGFEIPANDOMEDX, INC., CA$754,319ZRG1
2018High-throughput screening of arrayed single cells for automated analysis of phenotypic heterogeneity2R44GM122149-02FORBES, ZACHARY GRAHAMCELLDOM, INC., CA$751,561ZRG1
2018Deconvolution and Assembly of Metagenomes Using Chromatin Conformation Capture2R44AI122654-02A1LIACHKO, IVANPHASE GENOMICS, INC., WA$750,250ZRG1
2018Wireless Sensor Inserts for Combating Incontinence-Associated Dermatitis2R44NR014614-02A1 · under PA-16-302PROKOPUK, NICHOLASJPTECHNOLOGIES, INC., CA$750,000ZRG1
2018A robust heterologous expression system of intact fungal secondary metabolite gene clusters for natural product discovery in Aspergillus nidulans2R44AT009158-02BOK, JIN WOOKELLEHER, NEIL LWU, CHENGCANG CHARLESINTACT GENOMICS, INC., MO$750,000ZRG1
2018Automated image-based biomarker computation tools for diabetic retinopathy2R44TR000377-05SOLANKI, KAUSHALEYENUK, INC., CA$750,000ZRG1
2018A Biodegradable Vascular Coupling Device for End-to-End Anastomosis2R44HL132767-02A1AGARWAL, JAYANT PRASADGALE, BRUCELI, HUIZHONGSANT, HIMANSHUMICROSURGICAL INNOVATIONS, INC., UT$750,000ZRG1
2018An Open Web Service For Fragment-based Design of Small Molecule Inhibitors2R44GM109549-02A1KULP, JOHN LCONIFER POINT PHARMACEUTICALS, LLC, PA$749,999ZRG1
2018Development of new anti-epilepsy treatments targeting cellular energetics through mitochondrial modulation with optimal pharmacokinetics and toxicity profiles2R44NS097047-02CHAN, SHERINE SHIMES, RICHARD ANEUROENE THERAPEUTICS INC, DC$749,959ZRG1
2018An Ultrasensitive, High-Throughput, and Low-Cost Autoimmunity Panel for the Early Diagnosis and Improved Treatment of Type 1 Diabetes2R44DK111005-02SEFTEL, DAVIDENABLE BIOSCIENCES, INC., CA$749,838ZRG1
2018A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction2R44HL132649-02BAUER, PHILIPMALDONADO, CLAUDIOTANG, XIAN-LIANGENDOPROTECH, INC., KY$749,712ZRG1
2018Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor2R44DK110972-02PAYNE, FORRESTSFC FLUIDICS, LLC, AR$748,973ZRG1
2018Additive Manufacturing of Ceramic Dental Restorations2R44DE025803-02A1KUTSCH, JEFFREY JTECHNOLOGY ASSESSMENT AND TRANSFER, INC., MD$748,795ZRG1
2018The Variant Explorer: a cloud-based data integration and visualization system for improving clinical interpretation of sequenced genetic variants.2R44GM117644-02 · under PA-16-302XU, XINGSOLVE, INC., NY$748,556ZRG1
2018High-throughput nanoMEA-based Proarrhythmia Assay2R44HL131169-02A1GEISSE, NICHOLAS ANDREWCURI BIO INC, WA$748,435ZRG1
2018IND-Enabling Studies of ZB716, an Orally Bioavailable SERD2R44CA213462-02WANG, GUANGDIZENOPHARM, LLC, LA$748,371ZRG1
2018A Graphene Nanoparticle-Based X-ray Computed Tomography Contrast Agent ForSubjects At Risk for Contrast Induced Nephropathy2R44DK112550-02SITHARAMAN, BALAJITOUSSAINT, JIMMY DEONTHERAGNOSTIC TECHNOLOGIES, INC., NY$748,000ZRG1
2018Clinical Testing of the First Suspension BHK-M Cell Platform Derived Biotherapeutic2R44HL110448-02A1DENNING, GABRIELADOERING, CHRISTOPHER BRADLEYEXPRESSION THERAPEUTICS, GA$747,641ZRG1
2018Universal VLP-Based Flu Vaccine:Broadly protective (universal) virus-like particle (VLP) based influenza vaccine that can neutralize a broad spectrum of influenza A virus subtypes.2R44AI106145-03GALARZA, JOSE M.TECHNOVAX, INC., NY$746,924ZRG1
2018Mobility Rehab: A Biofeedback System for Mobility Rehabilitation for Older Adults2R44AG056012-02EL-GOHARY, MAHMOUDAPDM, INC., OR$746,713ZRG1
2018Enabling electron-induced fragmentation in tandem mass spectrometry2R44GM123855-02VOINOV, VALERY G.E-MSION, INC., OR$746,325ZRG1
2018An intravascular Bioartificial Pancreas (iBAP)2R44DK104299-02BLAHA, CHARLESSILICON KIDNEY, LLC, CA$746,324ZRG1
2018Comprehensive but simple encoding of bioassays to accelerate translational drug discovery2R44TR000185-04A1 · under PA-16-302BUNIN, BARRY ACOLLABORATIVE DRUG DISCOVERY, INC., CA$744,321ZRG1
2018Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates2R44AR070088-02A1LAPIERRE, LEIGHTONEVOKE MEDICAL, LLC, KS$738,612ZRG1
2018Expanding the Click City: Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products2R44DA044025-02ANDREWS, JUDY AGORDON, JUDITH SARAHOREGON RES BEHAVIORAL INTERVENTION STRAT, OR$732,500ZRG1
2018Automated Harness Tightener for Child Safety Seat2R44HD085660-02A1RYDBERG, NICKMINNESOTA HEALTHSOLUTIONS CORPORATION, MN$732,443ZRG1
2018Three-dimensional testicular cell co-culture model for reproductive toxicity screening2R44ES027374-02YIN, LEIREPROTOX BIOTECH, LLC, GA$729,931ZRG1
2018Blood Flow Velocimetry Using Digital Subtraction Angiography2R44HL132664-02SINGH, BIPINRADIATION MONITORING DEVICES, INC., MA$724,960ZRG1
2018Mobile App Promoting Sexual Health for Young Black Men who Have Sex with Men2R44MD010324-02A1COYLE, KARIN KRISTINAKUHN, TAMARA J.DFUSION, INC., CA$724,745ZRG1
2018Tools for drug efficacy studies in perfused tissue models2R44TR001286-02 · under PA-16-302VUKASINOVIC, JELENALENA BIOSCIENCES, INC., GA$724,224ZRG1
2018Development of a TransApical to Aorta Double Lumen Cannula for a Neonate LVAD2R44HL120370-02TOPAZ, STEPHEN RW-Z BIOTECH, LLC, KY$714,777ZRG1
2018PINPOINT: Gaming technology to engage adolescent sickle cell patients in precision pain Phase I2R44MD010746-02MYERS, VALERIE HKLEIN BUENDEL, INC., CO$700,201ZRG1
2018Centralized assay datasets for modelling support of small drug discovery organizations2R44GM122196-02A1EKINS, SEANCOLLABORATIONS PHARMACEUTICALS, INC., NC$694,172ZRG1
2018Effect of Repeated Administration of G-CSF on Hot Flashes and Other Vasomotor Symptoms of Menopause1R43AG056209-01A1 · under PA-16-302DUKE, RICHARD CMENOGENIX, INC., CO$693,360ZRG1
2018Developing a prenatal biologic therapy to mitigate ASD risk from maternal autoantibodies to Caspr22R44HD092128-02BURCH, RONALD MSPARK2FLAME, INC., NY$677,502ZRG1
2018Optical Dosimeter-guided Photodynamic Therapy2R44CA213607-02ZHAO, YOUBOPHYSICAL SCIENCES, INC, MA$674,353ZRG1
2018Non-Invasive Intraoral LED Phototherapy Device for the Prevention and Treatment of Oral Mucositis2R44DE026082-02A1KOTHARI, VEDANG PLUMITEX, INC., OH$669,673ZRG1
2018Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative2R44ES022885-02MAJUMDAR, SUDIPTOCOMPACT MEMBRANE SYSTEMS, INC., DE$664,015ZRG1
2018A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation2R44GM117657-02RUPPERT, DAVIDDEEP BLUE MEDICAL ADVANCES, INC., NC$644,589ZRG1
2018miR-SEQ: Highly efficient targeted quantification of extracellular miRNAs by Next Generation Sequencing2R44GM115124-03 · under PA-16-302BARBERAN-SOLER, SERGIOSOMAGENICS, INC., CA$623,228ZRG1
2018High Subzero Equilibrium VCA Cryopreservation2R44AI124835-02TAYLOR, MICHAEL JOHNUYGUN, KORKUTSYLVATICA BIOTECH, INC., SC$622,651ZRG1
2018Caminamos: A location-based Smartphone App for Latinas to Connect with Nearby Walking Partners2R44MD009652-02MYERS, VALERIE HKLEIN BUENDEL, INC., CO$619,156ZRG1
2018Clinical optical coherence tomography for retinal metabolic imaging2R44EY026466-02 · under PA-16-302KURANOV, ROMANOPTICENT, INC., IL$617,592ZRG1
2018A Point of Care Test to Monitor and Promote Adherence to PrEP for HIV Prevention2R44MH114864-02DAUGHTRIDGE, GIFFINURSURE, INC., PA$613,679ZRG1
2018Self-advocacy training for students with cochlear implants entering higher education2R44DC013503-02HOLTZ, KRISTEN DKDH RESEARCH AND COMMUNICATION, INC., GA$612,952ZRG1
2018Rapid response toxicology prediction platform2R44ES026909-02 · under PA-16-302MYATT, GLENN JOHNLEADSCOPE, INC., OH$612,360ZRG1
2018Splice sensors for cancer drug discovery2R44CA206804-02SOMALINGA, BALAJEELUCERNA, INC., NY$603,137ZRG1
2018GUANIDINIUM DERIVATIVES FOR THE TREATMENT OF OCULAR PAIN2R44EY025921-02DELWIG, ANTONSITEONE THERAPEUTICS, INC., CA$601,128ZRG1
2018CFI Pathogen Inactivation of Human Plasma Units1R44HL137605-01A1 · under PA-16-302CASTOR, TREVOR P.OCHIENG, WASHINGTONEAPHIOS CORPORATION, MA$599,617ZRG1
2018Monoclonal antibody for autoimmune disease2R44AI120433-02LARRICK, JAMES WPANORAMA RESEARCH, INC., CA$592,822ZRG1
2018HTS Assays for Targeting the cGAS-STING Pathway in Autoimmune Diseases and Cancer2R44GM123833-02LOWERY, ROBERT GBELLBROOK LABS, LLC, WI$591,712ZRG1
2018Plastic Parenteral Containers With Superior Oxygen Barrier Properties2R44HL129622-02JONSEN, DANIEL EVERETTTRIBOFILM RESEARCH, INC., NC$585,808ZRG1
2018Low-temperataure plasma decontamination of pharmaceutical manufacturing fill/finish operations2R44TR001847-02 · under PA-16-302GALBALLY-KINNEY, KRISTIN LPHYSICAL SCIENCES, INC, MA$583,124ZRG1
2018Protect Yourself! Abuse Prevention for People with Intellectual Disabilities2R44HD079119-02SHEEHAN, MARTIN R.DOUBLE S INSTRUCTIONAL SYSTEMS, OR$572,386ZRG1
2018Improving Patient Outcomes through Tracking and Displaying the Disinfection Status of Equipment and Area2R44NR016638-02 · under PA-16-302STIBICH, MARK AXENEX DISINFECTION SERVICES, LLC, TX$564,057ZRG1
2018An Integrative Approach to Control Group Creation for Prevention Research2R44AA024657-02HANSEN, WILLIAM B.PREVENTION STRATEGIES, LLC, NC$554,976ZRG1
2018New Technology to Improve Chemotherapy Safety for Cancer Patients and Health Workers1R43CA224598-01 · under PA-16-302SUNKARA, PRASADJ AND J SOLUTIONS, INC., IA$548,377ZRG1
2018Durable hydrophilic coating to promote effective condom use2R44HD089856-02CHIN, STACY LHYDROGLYDE COATINGS, LLC, MA$542,627ZRG1
2018Deploying retinal birefringence imaging in to the clinic for pediatric vision screening2R44EY027633-02BIRCH, EILEEN ELIZABETHSHAKA, JUSTINREBISCAN, LLC, MA$542,407ZRG1
2018Selective inhibition of CYP26A1 in the skin for the treatment of ichthyosis2R44AR069416-02ASTRUC DIAZ, FANNYDERMAXON, LLC, MT$536,029ZRG1
2018A Computer Tool for Aiding in Accurate Assessment of Indeterminate Lung Nodules2R44CA203058-02A1 · under PA-16-302MENG, XININTERNATIONAL INTELLIGENT INFOR/SOLU/LAB, PA$529,613ZRG1
2018Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina2R44EY023481-02 · under PA-16-302FERGUSON, R DANIELPHYSICAL SCIENCES, INC, MA$527,107ZRG1
2018Use of DNATrax and high fidelity computational methods to model transport of contaminants in urban environments2R44ES025070-02 · under PA-16-302ZOGRAFOS, ANTONIOSSAFETRACES, INC., CA$523,978ZRG1
2018Low-cost Personal Sampling Pump2R44OH010635-02A1MILLER-LIONBERG, DANIEL DACCESS SENSOR TECHNOLOGIES, LLC, CO$520,322ZRG1
2018Advancing Human Health by Lowering Barriers to Electrophysiology in Genetic Model Organisms2R44GM119906-02 · under PA-16-302LOCKERY, SHAWN RMCCORMICK, KATHRYN EROBERTS, WILLIAM MWEEKS, JANIS CNEMAMETRIX, INC., OR$510,448ZRG1
2018Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager2R44EY024186-02A1 · under PA-16-302MULLER, MATTHEW SAEON IMAGING, LLC, IN$505,350ZRG1
2018Fully automated enzymatic radiolabeling of biomolecules2R44EB023782-02A1DRAKE, CHRISTOPHER RICHARDSOFIE BIOSCIENCES, INC., CA$501,151ZRG1
2018Novel Polymer Matrix for Dental Applications2R44DE024013-02BOLSKAR, ROBERT DTDA RESEARCH, INC., CO$500,001ZRG1
2018Fast, quantitative analysis of trichloroethylene (TCE) in water2R44ES026513-02A1PETERMAN, MARK CONDAVIA, INC., CA$500,000ZRG1
2018Development of a Numerical Model for Microbubble Enhanced Treatment in HIFU Therapy2R44CA213866-02HSIAO, CHAO-TSUNGDYNAFLOW, INC., MD$500,000ZRG1
2018Expressive Speech Synthesis for Speech-Generating Devices2R44DC014173-02A1HERTZ, SUSAN RSYNFONICA, LLC, NY$499,999ZRG1
2018Improving drug safety for pregnant women by delivering current and authoritative information via mobile devices2R44DD001127-02 · under PA-16-302MARKHAM, GLENRIGHTANSWER.COM, INC., MI$499,961ZRG1
2018Evaluation of National Video Directly Observed Therapy Implementation2R44MD010521-03A1SEIGUER, SEBASTIANSHAH, MAUNANKEMOCHA MOBILE HEALTH, INC., MD$499,597ZRG1
2018A Tool to Improve Evaluation of Patient Navigation Services in Underserved Populations2R44MD011350-02BURHANSSTIPANOV, LINDANATIVE AMERICAN CANCER INITIATIVES, INC., CO$499,535ZRG1
2018Long non-coding RNA signatures to distinguish fibromyalgia syndrome from rheumatic diseases2R44AI129147-02AUNE, THOMAS M.SPURLOCK, CHARLES FLOYDIQUITY LABS, INC, TN$498,258ZRG1
2018Glycoprotein Immunoassay to Measure Protective Response to Lassa Vaccine1R43AI138836-01BOISEN, MATTHEW LZALGEN LABS, LLC, MD$497,084ZRG1
2018Development of immunoassays for highly sensitive diagnostic monitoring of traumatic brain injury using novel astroglial injury-defined biomarkers1R43NS106972-01VANMETER, TIMOTHY EIMMUNARRAY USA, INC., VA$496,078ZRG1
2018Ultra-Bright Fluorescent Probes for Flow Cytometry2R44GM126848-02YU, JIANGBOLAMPROGEN, INC., WA$494,939ZRG1
2018A New Rapid DNA Platform for Neonatal Sepsis Diagnostics2R44HD084019-02A1HODKO, DALIBORNEXOGEN, INC., CA$494,099ZRG1
2018Chitosan Gastrointestinal Hemostatic Dressing2R44DK104564-02A1ENESTVEDT, BRINTHA KMCCARTHY, SIMON JOHNXIE, HUATRICOL BIOMEDICAL, INC., OR$493,894ZRG1
2018Enhanced Treatment Management of Opioid-Dependence in an Office-Based Setting2R44DA033702-02MATTAI, ANANDMEDICASAFE, INC., NY$491,331ZRG1
2018A Direct-Reading Liquid Crystal Based Formaldehyde Dosimeter for Personal Exposure Monitoring2R44ES026474-02BEDOLLA PANTOJA, MARCO APLATYPUS TECHNOLOGIES, LLC, WI$487,008ZRG1
2018Quantitative Analysis of Single Molecule Microscopy2R44GM121113-02CHAO, YEN-CHINGASTERO TECHNOLOGIES, LLC, TX$486,798ZRG1
2018Sustained Release Travoprost Implant for Treatment of Glaucoma2R44EY028822-02A1MANDELL, KENNETH JLAYERBIO, INC., MA$485,176ZRG1
2018Transvascular access and aspiration of thoracic duct lymph using a novel ultrasound guided approach.2R44DK109876-02A1CALLAGHAN, MATTHEWLXS, INC., CA$483,956ZRG1
2018A Novel Immunological Probiotic for Treating Inflammatory Bowel Disease1R43DK117726-01A1FANGER, GARYRISE THERAPEUTICS, LLC, MD$480,497ZRG1
2018Development and validation of a novel non-invasive device for measuring the mechanical properties of cortical bone1R43AG058312-01 · under PA-16-302CLARK, BRIAN CDICK, ANDREWLOUCKS, ANNE BOSTEODX INC., OH$477,486ZRG1
2018Advanced Indoor Navigation Aid for Blind and Visually-Impaired Individuals in Unfamiliar Spaces2R44EY029213-02SCHAEFER, PHILIP RVORTANT TECHNOLOGIES, LLC, NC$473,472ZRG1
2018MULTI-REPORTER ISOBARIC LABELING REAGENTS FOR INCREASED MULTIPLEXING IN QUANTITATIVE PROTEOMICS2R44GM121157-02BRAUN, CRAIG RONALDERICKSON, BRIAN KEITHIQ PROTEOMICS, LLC, MA$463,440ZRG1
2018IND-enabling Epicardial Biopharmaceutical in the Diabetic Heart1R44HL140649-01A1RUIZ-LOZANO, PILARREGENCOR, INC., CA$444,786ZRG1
2018Development of a metabolomics and machine learning based high-throughput screening platform for data-driven drug discovery1R43GM130268-01BORDBAR, AARASHNEMKOV, TRAVISSINOPIA BIOSCIENCES, INC., CA$442,427ZRG1
2018A Computer Model of Renal Physiology for use as a FDA Medical Device Development Tool2R44FD005669-02 · under PA-16-302PRUETT, WILLIAM ANDREWHC SIMULATION, LLC, MS$441,039ZRG1
2018PIKFYVE antagonism as a therapy for C9ORF72-ALS/FTD1R44NS105156-01 · under PA-16-302ALWORTH, SAMUEL VZHOU, HONGYANACURASTEM, INC., CA$433,105ZRG1
2018HLS Potent, novel inhibitor of fibrinolytic hemorrhage- Phase II2R44HL137514-02REED, GUY LTRANSLATIONAL SCIENCES, INC., AZ$423,216ZRG1
2018Novel Biological Tissue for Vascular Patch1R43HL140763-01A1KASSAB, GHASSAN SLU, XIAOWANG, MENGJUN3DT HOLDINGS, LLC, CA$419,085ZRG1
2018DEVELOPMENT OF A PEDIATRIC CARDIAC AND RESPIRATORY ASSIST SYSTEM1R43HL144214-01DASSE, KURT AINSPIRED THERAPEUTICS, LLC, VA$415,921ZRG1
2018Development of an Anti-Embolic Micromesh Carotid Stent1R43HL140895-01 · under PA-16-302KEALEY, COLIN PATRICKNEUROSIGMA, INC., CA$415,743ZRG1
2018New-Generation of Fluorescently-Labeled Charge-Neutralized Oligonucleotides as Probes for the Detection and Quantification of MicroRNAs and Oligonucleotide-Based Therapeutics in Biological Samples1R43GM130187-01TABATADZE, DAVID RZATA PHARMACEUTICALS, INC., MA$402,225ZRG1
2018HLS- A Phase 1 Open-Label Dose-Escalation with Expansion Study of SX-682 in MDS Patients1R44HL142389-01KAHN, STUART JMAEDA, DEAN YOSHIMASASYNTRIX BIOSYSTEMS, INC., WA$398,444ZRG1
2018Preclinical Testing of Splice Modulating Oligonucleotides Targeting SCN8A to Treat Dravet Syndrome1R43NS105291-01 · under PA-16-302TALLENT, MELANIE KLIFESPLICE PHARMA, LLC, PA$389,793ZRG1
2018Introducing Neuroscience and Neurocomputation Concepts to High School Students using Brain-based Neurorobots1R43NS108850-01GAGE, GREGORY JOHNHARRIS, CHRISTOPHER AIDANBACKYARD BRAINS, INC., MI$386,013ZRG1

Showing the 200 most recent of 3,426 awards.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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