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NIH funding notice PA-16-077

NIH Pathway to Independence Award (Parent K99/R00)

Closed on May 7, 2016.

Posted
January 8, 2016
Close date
May 7, 2016
Activity codes
K99, R00
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, ORIP, OBSSR, ODS, IC

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-15-083 NIH Pathway to Independence Award (Parent K99/R00)
  2. 2 steps back: PA-14-042 NIH Pathway to Independence Award (Parent K99/R00)
  3. 3 steps back: PA-11-197 NIH Pathway to Independence Award (Parent K99/R00)
  4. 4 steps back: PA-10-063 NIH Pathway to Independence Award (Parent K99/R00)
  5. 5 steps back: PA-09-036 NIH Pathway to Independence Award (K99/R00)
  6. 6 steps back: PA-07-297 NIH Pathway to Independence (PI) Award (K99/R00)
  7. 7 steps back: PA-06-133

Replaced by PA-16-193.

Who won it before

725 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $79,499,636 in first-year total cost, median $101,195.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I]130
  2. NST-2 Study Section [NST-2]40
  3. Special Emphasis Panel[ZGM1 TWD-A (KR)]35
  4. Biological Aging Study Section[NIA-B]22
  5. Special Emphasis Panel[ZHL1 CSR-P (O1)]22

Most frequent institutions

  1. STANFORD UNIVERSITY59
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO34
  3. MASSACHUSETTS GENERAL HOSPITAL25
  4. COLUMBIA UNIVERSITY HEALTH SCIENCES18
  5. DANA-FARBER CANCER INST18
Competing awards under PA-16-077 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Prefrontal Pathways Engaged in Excessive Alcohol Consumption1K99AA024507-01A1 · under PA-15-083SALLING, MICHAEL CHARLESCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$180,651AA
2017Elucidating a Novel Mechanism for SPOP in Suppressing Prostate Tumorigenesis1K99CA212292-01ZHANG, JINFANGBETH ISRAEL DEACONESS MEDICAL CENTER, MA$168,804NCI
2017Uncovering compensatory mechanisms in family members with disease causing mutations of pulmonary hypertension1K99HL135258-01GU, MINGXIASTANFORD UNIVERSITY, CA$168,048MTI
2017AUTS2 and the chromatin dynamics of alcohol use disorders1K99AA024837-01A1STAFFORD, JAMES MNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$163,997AA
2017Neurodevelopmental effects of Perfluorinated Chemicals1K99ES026729-01A1LIEW, ZEYANUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$158,328ZES1
2017Neurons of the medial habenula regulate behavioral responses to nicotine in mouse1K99DA041500-01A1PETERS, CHRISTIANUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$153,130ZDA1
2017LONG NON-CODING RNA REGULATION OF ALCOHOL DRINKING BEHAVIOR1K99AA024836-01A1FARRIS, SEAN PUNIVERSITY OF TEXAS AT AUSTIN, TX$153,090ZAA1
2017Targeting APOBEC3A-expressing cancer cells with ATR inhibitors1K99CA212154-01BUISSON, REMIMASSACHUSETTS GENERAL HOSPITAL, MA$142,560NCI
2017New Approaches for Vaccine Development against HIV1K99AI127243-01A1DOSENOVIC, PIA KAROLINROCKEFELLER UNIVERSITY, NY$142,007AIDS
2017Alcohol-induced neuroadapation of prefrontal cortical projections1K99AA025408-01VARODAYAN, FLORENCE PRABHASCRIPPS RESEARCH INSTITUTE, THE, CA$141,750ZAA1
2017Midbrain cellular and circuit dynamics of cocaine seeking1K99DA042895-01SAUNDERS, BENJAMIN THOMASJOHNS HOPKINS UNIVERSITY, MD$138,912ZDA1
2017Role of CB1 Receptors in Opioid Tolerance During Pain1K99DA041467-01A1WILSON-POE, ADRIANNE RAEWASHINGTON UNIVERSITY, MO$137,954ZDA1
2017The PI3K/AKT Pathway Regulates Histone H3 Modification1K99CA204601-01A1SPANGLE, JENNIFER MARIEDANA-FARBER CANCER INST, MA$136,080NCI
2017Flow Regulation of YAP/TAZ in Atherogenesis and Therapeutic Development1K99HL135416-01WANG, MARK KUEI-CHUNUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$135,864MTI
2017Imaging neural dynamics at high temporal resolution in sleep and sleep deprivation1K99MH111748-01LEWIS, LAURA DIANEMASSACHUSETTS GENERAL HOSPITAL, MA$131,040ZMH1
2017Chemical editing of nanoscale proteoglycan architecture and organization to control cellular differentiation1K99HD090292-01HUANG, MIA LUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$130,334CHHD
2017Towards Improving Bone Marrow Transplantation via Inhibition of 15-PGDH1K99HL135740-01DESAI, AMARCASE WESTERN RESERVE UNIVERSITY, OH$129,870MTI
2017Single-cell analysis of somatic mutation in aging and neurodegenerative disease in the human brain1K99AG054748-01LODATO, MICHAEL ANTHONYBOSTON CHILDREN'S HOSPITAL, MA$129,870NIA
2017Determining the Neurodevelopmental Effects of Transition from Breastfeeding to Infant Formula using a Novel Biomarker1K99HD087523-01A1AUSTIN, CHRISTINEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$129,820CHHD
2017The role of serotonin signaling in the nucleus accumbens in excessive alcohol drinking1K99AA024215-01A1 · under PA-15-083MARCINKIEWCZ, CATHERINE ANNEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$128,592AA
2017Mechanisms by which the myometrial ECM modulates myometrial cell function1K99HD090301-01NALLASAMY, SHANMUGASUNDARAMUT SOUTHWESTERN MEDICAL CENTER, TX$125,575CHHD
2017Maternal Exposure to Air Pollution and Early Pregnancy Outcomes1K99ES026648-01A1GASKINS, AUDREY JANEHARVARD SCHOOL OF PUBLIC HEALTH, MA$122,769ZES1
2017SCN5A (Nav1.5): Predicting the Consequence of Missense Single- Nucleotide Polymorphisms.1K99HL135442-01KRONCKE, BRETT MVANDERBILT UNIVERSITY MEDICAL CENTER, TN$122,526MTI
2017A molecular signaling pathway underlying differential predisposition of ApoE4 genotype to Alzheimer's disease1K99AG054616-01HUANG, YU-WEN ALVINSTANFORD UNIVERSITY, CA$118,681NIA
2017Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administration1K99DA041493-01A1ORSINI, CAITLIN ANNEUNIVERSITY OF FLORIDA, FL$118,587ZDA1
2017Alternative splicing regulation by extracellular matrix mechanics: a self-tuning tool to control cell microenvironmental adaptation and tumor progression1K99CA212270-01BORDELEAU, FRANCOISVANDERBILT UNIVERSITY, TN$112,478NCI
2017Altered Treg differentiation in ALD: a novel role for anaphylatoxins C3a and C5a1K99AA025386-01SMATHERS MCCULLOUGH, REBECCA LEANNECLEVELAND CLINIC LERNER COM-CWRU, OH$110,939AA
2017Causal Mechanisms for Sustainable Adaptation to Adverse Heat and Precipitation Health Effects1K99ES026198-01A1GRONLUND, CARINAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$108,136ZES1
2017Determination of maternal-fetal phosphate transport mechanisms and the role of sodium-dependent phosphate transporters in extraembryonic tissues1K99HD090198-01WALLINGFORD, MARY CATHERINEUNIVERSITY OF WASHINGTON, WA$107,984CHHD
2017Structural Studies of the Coronavirus Life Cycle1K99AI123498-01A1KIRCHDOERFER, ROBERT NSCRIPPS RESEARCH INSTITUTE, THE, CA$103,478MID
2017TGFBeta signaling pathway in arterial cell fate regulation1K99HL135321-01LIZAMA, CARLOSUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$103,130MTI
2017Molecular Mechanisms and Social Constructs: How genes and environment regulate the rate of aging1K99AG052604-01A1LEVINE, MORGAN ELYSEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$101,122NIA
2017Cytoskeletal regulation and Yap/Taz activity in differentiating retinal neurons1K99EY027467-01HENLE, STEVEN JMEDICAL COLLEGE OF WISCONSIN, WI$99,997ZEY1
2017Statistical Methods for the Normalization and Quantification of Single-Cell RNA-Sequencing Data1K99HG009007-01A1HICKS, STEPHANIE CARINNEDANA-FARBER CANCER INST, MA$98,178GNOM
2017The Idol-ApoE receptor pathway in Alzheimer's disease1K99AG054736-01GAO, JIEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$96,606NIA
2017NIMA-like kinase NEK1 as a regulator of mammalian gametogenesis1K99HD090289-01BRIENO-ENRIQUEZ, MIGUEL ANGELCORNELL UNIVERSITY, NY$93,254CHHD
2017Rod photoreceptor function in retinitis pigmentosa1K99EY027460-01BENNETT, LEA DRETINA FOUNDATION OF THE SOUTHWEST, TX$93,023ZEY1
2017Genomic imprinting in circuits for social behavior1K99MH111912-01BONTHUIS, PAUL JEFFREYUNIVERSITY OF UTAH, UT$91,958ZMH1
2017Natural Variation in the Growth and Development of the ACL Complex1K99AR070903-01SCHLECHT, STEPHENUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$91,800AMS
2017Partial mGlu5 Negative Allosteric Modulators to Prevent Relapse to Cocaine Abuse1K99DA042129-01 · under PA-15-083GOULD, ROBERT WARRENVANDERBILT UNIVERSITY, TN$91,732ZDA1
2017Uncovering mechanisms of myelin formation and regeneration in the live brain1K99NS099469-01HILL, ROBERTYALE UNIVERSITY, CT$90,666NST
2017Coupling promoter choice and alternative RNA splicing in the mammalian Protocadherin gene cluster1K99GM121815-01CANZIO, DANIELECOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$90,000ZGM1
2017Engineered flavin-dependent enzymes for probing redox environment and regulation1K99GM121856-01CRACAN, VALENTINMASSACHUSETTS GENERAL HOSPITAL, MA$90,000ZGM1
2017The Effect of Multicellularity on Bacterial Interactions and Diversity1K99GM121873-01LYONS, NICHOLAS ANTHONYHARVARD MEDICAL SCHOOL, MA$90,000ZGM1
2017Mapping vertebrate differentiation hierarchies with high-throughput single cell transcriptomics1K99GM121852-01WAGNER, DANIEL EHARVARD MEDICAL SCHOOL, MA$89,142ZGM1
2017Investigating the role of AAA+-ATPases in peroxisome biology1K99GM121880-01GARDNER, BROOKE MEGHANUNIVERSITY OF CALIFORNIA BERKELEY, CA$86,400ZGM1
2017Vascular mechanisms and tDCS treatment of gait and posture in aging and age-related disease1K99AG051766-01A1JOR'DAN, AZIZAH J.HEBREW REHABILITATION CENTER FOR AGED, MA$3,321NIA
2016Multilevel approaches for embracing dyadic, egocentric and two-mode networks which address substance use disorders and HIV risk in Latina seasonal workers1K99DA041494-01A1 · under PA-15-083KANAMORI NISHIMURA, MARIANO JUANFLORIDA INTERNATIONAL UNIVERSITY, FL$183,004ZDA1
2016Investigating function of novel drug-induced synaptic changes in the VTA1K99DA041445-01 · under PA-15-083BEIER, KEVIN TSTANFORD UNIVERSITY, CA$180,943ZDA1
2016Deciphering the role of Lin28b in pancreatic cancer to guide therapeutic discovery1K99CA208032-01 · under PA-15-083KUGEL, SITAMASSACHUSETTS GENERAL HOSPITAL, MA$180,360NCI
2016Single Cell In Vivo Imaging Technology to Analyze Taxane Nano Formulations in Breast Cancer1K99CA207744-01 · under PA-15-083MILLER, MILES AMASSACHUSETTS GENERAL HOSPITAL, MA$179,280NCI
2016Multifunctional, GBM-activatable nanocarriers for image-guided photochemotherapy1K99CA194269-01A1 · under PA-15-083HUANG, HUANG CHIAOMASSACHUSETTS GENERAL HOSPITAL, MA$179,122NCI
2016Recapitulating Ductal Carcinoma on a Chip for Personalized Breast Cancer Therapy1K99CA201603-01A1 · under PA-15-083ZHANG, Y. SHRIKEBRIGHAM AND WOMEN'S HOSPITAL, MA$178,200NCI
2016Stigma, Risk Behaviors and Health Care among HIV-infected Russian People Who Inject Drugs1K99DA041245-01A1 · under PA-15-083LUNZE, KARSTENBOSTON MEDICAL CENTER, MA$177,435BSCH
2016Defining driver tumor-suppressors for melanoma using the zebrafish1K99CA201465-01 · under PA-15-083ABLAIN, JULIENBOSTON CHILDREN'S HOSPITAL, MA$171,990NCI
2016Autonomic remodeling and modulation therapy in heart failure and sudden death1K99HL130662-01 · under PA-15-083DEMAZUMDER, DEEPTANKARJOHNS HOPKINS UNIVERSITY, MD$171,720MTI
2016Mapping the Angiotensin II-TGFB-Integrin signaling triad to reveal therapeutic targets in aortic aneurysm1K99HL128787-01A1 · under PA-15-083PARKER, SARAH JCEDARS-SINAI MEDICAL CENTER, CA$170,992MTI
2016Elucidating Novel Akt Regulatory Mechanisms to Overcome Akt-mediated Therapeutic Resistance in Breast Cancer1K99CA207867-01 · under PA-15-083GAN, WENJIANBETH ISRAEL DEACONESS MEDICAL CENTER, MA$168,804NCI
2016Defining and manipulating quiescence associated DNA damage resistance in single cells1K99CA207727-01 · under PA-15-083STEWART-ORNSTEIN, JACOBHARVARD MEDICAL SCHOOL, MA$166,104NCI
2016US and International Evidence on Factors Leading to Tax Avoidance and Evasion and Their Impact on Drinking Behaviors and Consequences1K99AA024810-01 · under PA-15-083SHANG, CEUNIVERSITY OF ILLINOIS AT CHICAGO, IL$162,607AA
2016Identification of novel cooperating partners of MYCN in neuroblastoma tumorigenesis1K99CA197484-01A1 · under PA-15-083HUANG, MILLERUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$160,773NCI
2016Heterogeneity and bias of lineage negative progenitors in lung epithelial repair1K99HL131817-01 · under PA-15-083VAUGHAN, ANDREWUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$159,840MTI
2016Influence of chronic pain on mesolimbic dopamine activity and motivated behavior1K99DA040016-01 · under PA-14-042TAYLOR, ANNAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$158,544ZDA1
2016The Mathematics of Breast Cancer Overtreatment: Improving Treatment Choice through Effective Communication of Personalized Cancer Risk1K99CA207872-01 · under PA-15-083RYSER, MARCDUKE UNIVERSITY, NC$158,361NCI
2016MOLECULAR GUIDED SURGERY FOR IMPROVED RESECTION OF GLIOBLASTOMA MULTIFORME1K99CA190890-01A1 · under PA-15-083ELLIOTT, JONATHAN TDARTMOUTH COLLEGE, NH$157,680ZCA1
2016Comprehensive Reintegration Assistance for Women with Obstetric Fistula1K99HD086232-01 · under PA-15-083EL AYADI, ALISON MUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$157,350CHHD
2016Behavioral Epigenetics in Children: Exploring the Social and Ethical Implications of Translation1K99HG009154-01 · under PA-15-083LAPPE, MARTINE DNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$157,173ZRG1
2016Mechanisms Underlying Differential Effects of Neighborhood Poverty on Problematic Adolescent Drug Use1K99DA042127-01 · under PA-15-083RUDOLPH, KARA ELIZABETHUNIVERSITY OF CALIFORNIA BERKELEY, CA$155,590ZDA1
2016miR-34/449 miRNAs in airway multiciliated cells1K99HL128912-01A1 · under PA-15-083SONG, RUIUNIVERSITY OF CALIFORNIA BERKELEY, CA$154,440MTI
2016Endothelin - Mechanisms in Hypertension and Obesity1K99HL127178-01A1 · under PA-15-083SPEED, JOSHUA SUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$154,138MTI
2016Regulation of Mitochondrial Inner Membrane Organization1K99HL133372-01 · under PA-15-083FRIEDMAN, JONATHAN R.UNIVERSITY OF CALIFORNIA AT DAVIS, CA$153,684MTI
2016Role of SNF5 in regulating SWI/SNF complex assembly & targeting in rhabdoid tumor1K99CA197640-01A1 · under PA-15-083WANG, XIAOFENGDANA-FARBER CANCER INST, MA$151,649NCI
2016Characterization of menthol's effect on nicotine reinforcement and nicotinic receptor neurobiology1K99DA040047-01A1 · under PA-15-083HENDERSON, BRANDON JARRODCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$151,200ZDA1
2016Characterizing the resistance mechanisms to BET-bromodomain inhibition in MYC-amplified medulloblastoma1K99CA201592-01A1 · under PA-15-083BANDOPADHAYAY, PRATITIDANA-FARBER CANCER INST, MA$151,039NCI
2016Defining the Role of D1 and D2 Medium Spiny Neurons in Relapse to Cocaine Seeking1K99DA042111-01 · under PA-15-083CALIPARI, ERINICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$150,560ZDA1
2016Role of histone demethylated LSD1 as an epigenetic dependency in lymphoma1K99CA212276-01CHATZI, KATERINAWEILL MEDICAL COLL OF CORNELL UNIV, NY$148,904NCI
2016Manipulating hTERT splicing in lung cancer cells.1K99CA197672-01A1 · under PA-15-083LUDLOW, ANDREW TODDUT SOUTHWESTERN MEDICAL CENTER, TX$144,720NCI
2016Reflex responses to intermittent hypoxia in humans: Mechanisms and consequences1K99HL130339-01A1 · under PA-15-083LIMBERG, JACQUELINE KMAYO CLINIC ROCHESTER, MN$143,778MTI
2016Tissue flow genetics: using cartography to reveal forces driving morphogenesis1K99HD088708-01 · under PA-15-083STREICHAN, SEBASTIAN JUNIVERSITY OF CALIFORNIA SANTA BARBARA, CA$143,357CHHD
2016Trauma induced endothelial cell Ca2+ signaling1K99HL133451-01 · under PA-15-083COLLIER, DANIEL MOHRUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$142,830MTI
2016Mechanisms of metabolic, inflammatory and healthspan enhancement by 17a-estradiol1K99AG051661-01A1 · under PA-15-083STOUT, MICHAEL BUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$138,764NIA
2016A functional genomics approach to determine the mechanism of cellular response to new anti-cancer drugs1K99CA204602-01 · under PA-15-083GILBERT, LUKEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$138,672NCI
2016Genetic Mechanisms of Congenital Heart Disease1K99HL130523-01 · under PA-15-083PRIEST, JAMES R.STANFORD UNIVERSITY, CA$138,412MTI
2016NSD1 Inactivation in Head and Neck Cancer1K99CA212257-01LU, CHAOROCKEFELLER UNIVERSITY, NY$137,862NCI
2016Role of aberrant cytokine signaling in myeloproliferative disorders1K99HL122503-01A1 · under PA-15-083KLEPPE, MARIASLOAN-KETTERING INST CAN RESEARCH, NY$137,727MTI
2016Studying the Role of Aneuploidy in Cancer Immune Evasion1K99CA212621-01DAVOLI, TERESABRIGHAM AND WOMEN'S HOSPITAL, MA$137,124NCI
2016Methamphetamine and Parkinson's disease: converging mechanisms of pathogenesis1K99DA039253-01A1 · under PA-15-083GRAVES, STEVEN MICHAELNORTHWESTERN UNIVERSITY AT CHICAGO, IL$136,944ZDA1
2016Pharmacoepidemiologic Studies of Prescription Opioid Analgesic Risks1K99DA040727-01 · under PA-15-083QUINN, PATRICK DONOVANTRUSTEES OF INDIANA UNIVERSITY, IN$136,783ZDA1
2016Hypertension and Inflammation1K99HL130456-01A1 · under PA-15-083CORNELIUS, DENISE CRESHUNUNIVERSITY OF MISSISSIPPI MED CTR, MS$136,210MTI
2016Cumulative Victimization and Women's Health Risks: Development of an Intervention1K99HD082350-01A1 · under PA-15-083SABRI, BUSHRAJOHNS HOPKINS UNIVERSITY, MD$135,945CHHD
2016Bridging the gap between transcriptional activation and cell fate specification in the Drosophila visual system1K99EY027016-01 · under PA-15-083PERRY, MICHAEL WILLIAMNEW YORK UNIVERSITY, NY$135,789ZEY1
2016Proinflammatory and hyperinsulinemic dietary patterns and colorectal cancer risk: role of the metabolome1K99CA207736-01 · under PA-15-083TABUNG, FRED KINYUYHARVARD SCHOOL OF PUBLIC HEALTH, MA$135,774NCI
2016Examining the independent and joint contributions of socioeconomic status and bilingualism on early cognitive development1K99HD086255-01A1 · under PA-15-083BRITO, NATALIE HIROMINEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$135,438CHHD
2016Algorithms to link signaling pathways with transcriptional programs for precision medicine1K99CA207871-01 · under PA-15-083OSMANBEYOGLU, HATICE ULKUSLOAN-KETTERING INST CAN RESEARCH, NY$134,904NCI
2016Metabolic hormones, aging, and Alzheimer's Disease1K99AG050490-01A1 · under PA-15-083MORRIS, JILL KATHLEENUNIVERSITY OF KANSAS MEDICAL CENTER, KS$133,920NIA
2016Chronic Alcohol and the Neurocircuitry of Aversion1K99AA024208-01A1 · under PA-15-083GLOVER, ELIZABETH JMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$133,879ZAA1
2016Mechanisms of FoxA1 Latent Enhancer Formation in Response to Proinflammatory Signaling in Hormone Dependent Cancers1K99CA204628-01 · under PA-15-083FRANCO, HECTOR LUISUT SOUTHWESTERN MEDICAL CENTER, TX$133,791NCI
2016Nanotechnology for magnetic endothelialization of implantable cardiovascular devices1K99HL129068-01A1 · under PA-15-083TEFFT, BRANDON JMAYO CLINIC ROCHESTER, MN$133,434MTI
2016The Role of Dopamine in Modulating Relapse-induced Transient Synaptic Plasticity1K99DA041462-01 · under PA-15-083SPENCER, SADE MONIQUEMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$133,368ZDA1
2016Metabolic Regulation of Neurodegeneration in Tauopathy1K99AG053439-01 · under PA-15-083CHEN, XUJ. DAVID GLADSTONE INSTITUTES, CA$133,272NIA
2016Developing humanized mouse models for the study of HIV-1 latency and viral eradication1K99AI125065-01 · under PA-15-083SHAN, LIANGYALE UNIVERSITY, CT$133,110AIDS
2016Understanding The Molecular And Cellular RegulationOf Cilia Assembly And Regeneration In Multiciliated Cells1K99HL133606-01 · under PA-15-083KULKARNI, SAURABH SYALE UNIVERSITY, CT$133,110MTI
2016Investigating the role of RBM10-regulated alternative splicing in lung tumorigenesis1K99CA208028-01 · under PA-15-083CHOI, PETER S.DANA-FARBER CANCER INST, MA$133,108NCI
2016Molecular mechanisms of mucociliary function and airway clearance1K99HL127275-01A1 · under PA-15-083WALENTEK, PETERUNIVERSITY OF CALIFORNIA BERKELEY, CA$132,940MTI
2016Molecular Mechanisms of Rapamycin-induced Reversal of Cardiac Aging1K99AG051735-01A1 · under PA-15-083CHIAO, YING ANNUNIVERSITY OF WASHINGTON, WA$132,867NIA
2016Maternal inflammation, diet and gut microbiome in HIV: impact on infant outcomes1K99HD089753-01 · under PA-15-083SHIVAKOTI, RUPAKJOHNS HOPKINS UNIVERSITY, MD$131,198ACE
2016Neuronal subtype and circuit-specific epigenetic mechanisms in addiction1K99DA040744-01A1 · under PA-15-083SARTOR, GREGORY CHARLESUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$130,953ZDA1
2016Neural circuitry for state-dependent control of cortical auditory processing and perception1K99MH106744-01A1 · under PA-15-083CARCEA, IOANANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$130,474ZMH1
2016Neural mechanisms of probability estimation during decision-making1K99MH111926-01CONSTANTINOPLE, CHRISTINE MPRINCETON UNIVERSITY, NJ$130,140ZMH1
2016Identifying cellular and molecular substrates of treatment-resistant depression.1K99MH108719-01 · under PA-15-083ANACKER, CHRISTOPHNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$129,872ZMH1
2016High resolution measures of behavioral cancer risk factors from mobile technology1K99CA201542-01 · under PA-15-083JAMES, PETERHARVARD SCHOOL OF PUBLIC HEALTH, MA$129,418NCI
2016Reverse Engineering the Alveolus: From cellular to microenvironment specification during development1K99HL127267-01A1 · under PA-15-083BROWNFIELD, DOUGLAS GLENNSTANFORD UNIVERSITY, CA$128,942MTI
2016INHIBITION OF STREPTOCOCCUS MUTANS BY ORAL COMMENSAL STREPTOCOCCI AND NITRITE-MEDIATED ACTIVITY1K99DE025913-01A1SCOFFIELD, JESSICA AUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$128,833DSR
2016Defining oxidative stress induced changes in RPE that control RPE and photoreceptor degeneration1K99EY027013-01 · under PA-15-083BISWAL, MANAS RUNIVERSITY OF FLORIDA, FL$128,817ZEY1
2016Disparate Exposures, Disparate Outcomes: The Effect of Cumulative Disadvantage1K99MD011304-01BRAVO, MERCEDES AURELIARICE UNIVERSITY, TX$128,736ZMD1
2016Investigation and targeting of the transcriptional and epigenetic landscape of Small Cell Lung Cancer1K99CA201618-01A1CHRISTENSEN, CAMILLA LDANA-FARBER CANCER INST, MA$128,690NCI
2016Exploring Glycobiology and Discovering Biomarkers for Pancreatic Cancer1K99CA204725-01A1 · under PA-15-083ENGLE, DANNIELLECOLD SPRING HARBOR LABORATORY, NY$128,235NCI
2016Modulatory control of basal ganglia microcircuitry in cognitive flexibility and psychiatric disease1K99MH110597-01 · under PA-15-083OWEN, SCOTTJ. DAVID GLADSTONE INSTITUTES, CA$127,872ZMH1
2016Functional Neuroanatomy of Circuits Governing Parental Behavior1K99HD085188-01A1 · under PA-15-083AUTRY, ANITAHARVARD UNIVERSITY, MA$127,845CHHD
2016Targeting mechanisms of inter-organelle communication to promote healthy aging1K99AG052666-01A1BURKEWITZ, KRISTOPHERHARVARD SCHOOL OF PUBLIC HEALTH, MA$127,823NIA
2016Listening to Mom in the NICU: Neural, Clinical and Language Outcomes1K99HD084749-01A1 · under PA-15-083TRAVIS, KATHERINE ELIZABETHSTANFORD UNIVERSITY, CA$127,683CHHD
2016Cardiac Mitohormesis Protects Against Diabetic Cardiomyopathy Through Mitophagy1K99HL130416-01A1 · under PA-15-083ONG, SANG GINGSTANFORD UNIVERSITY, CA$127,683MTI
2016Regulation of hippocampal plasticity and learning and memory by a bloodborne rejuvenation factor1K99AG051711-01A1 · under PA-15-083CASTELLANO, JOSEPH MICHAELSTANFORD UNIVERSITY, CA$127,683NIA
2016Gene regulatory analysis of social integration and resilience during aging1K99AG051764-01A1 · under PA-15-083SNYDER-MACKLER, NOAHDUKE UNIVERSITY, NC$127,683NIA
2016The histone code of neuronal function and dysfunction1K99MH111836-01KORB, ERICA MEGANROCKEFELLER UNIVERSITY, NY$127,062ZMH1
2016Complex Systems Science Approaches to Addressing Oral Health Disparities1K99DE025917-01A1 · under PA-15-083HEATON, BRENDABOSTON UNIVERSITY MEDICAL CAMPUS, MA$126,906DSR
2016An investigation of the roles of mechanical signaling in YAP-mediated tooth renewal1K99DE025874-01 · under PA-15-083HU, JIMMY KUANG-HSIENUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$126,630ZDE1
2016Racial Disparities in Alzheimer's Disease and Related Dementias: The Role of Blood Pressure Throughout Adulthood1K99AG053410-01 · under PA-15-083MAYEDA, ELIZABETH ROSEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$126,291NIA
2016Intratumor heterogeneity and therapeutic resistance1K99CA201606-01A1 · under PA-15-083JANISZEWSKA, MICHALINADANA-FARBER CANCER INST, MA$126,232NCI
2016Prolonged Progenitor Maintenance Sculpts the Upper Face1K99DE026239-01 · under PA-15-083BARSKE, LINDSEY ANNEUNIVERSITY OF SOUTHERN CALIFORNIA, CA$126,225DSR
2016Cerebrovascular Abnormalities in Preeclampsia1K99HL129192-01A1 · under PA-15-083WARRINGTON, JUNIE PAULAUNIVERSITY OF MISSISSIPPI MED CTR, MS$124,957MTI
2016Investigating the role of the extracellular matrix in metastasis and chemo-resistance1K99CA207866-01 · under PA-15-083OUDIN, MADELEINE JULIEMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$124,569NCI
2016Regulation of neuronal morphogenesis and remodeling by the skin1K99HD086271-01 · under PA-15-083RASMUSSEN, JEFFREY PHILIPUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$123,390CHHD
2016Measuring Inequality in Early Mortality Across All Births in the Developing World1K99HD088727-01 · under PA-15-083RAMOS, ANTONIO PEDROUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$123,390CHHD
2016Arbitration Between Goal-directed and Habitual Ethanol Seeking by the Nucleus Accumbens Shell.1K99AA024499-01A1 · under PA-15-083BARKER, JACQUELINE MMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$123,063AA
2016Roles of tumor-derived PTHrP in skeletal muscle atrophy and cancer cachexia1K99CA197410-01A1 · under PA-15-083KIR, SERKANDANA-FARBER CANCER INST, MA$122,256NCI
2016Pathological TNFR1 expressing CD4+ T-cells are critical for HF progression1K99HL132123-01 · under PA-15-083BANSAL, SHYAM SUNDERUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$121,559MTI
2016Functional specialization of compartmentalized beta2-adrenergic signaling in neurons1K99MH109633-01 · under PA-15-083TSVETANOVA, NIKOLETA GEORGIEVAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,230ZMH1
2016MicroRNA-mediated mechanisms of heroin drug seeking1K99DA041469-01 · under PA-15-083DAWS, STEPHANIESCRIPPS FLORIDA, FL$120,651ZDA1
2016Neural circuitry for flexible control of auditory perception and behavior1K99DC015014-01 · under PA-15-083KUCHIBHOTLA, KISHORE VNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$119,893CDRC
2016Deconstructing the molecular mechanisms of Notch receptor-ligand selectivity1K99CA204738-01 · under PA-15-083LUCA, VINCENT CHRISTOPHERSTANFORD UNIVERSITY, CA$119,850NCI
2016The origins of chromosome rearrangement in the cancer genome1K99CA212290-01MACIEJOWSKI, JOHNROCKEFELLER UNIVERSITY, NY$119,783NCI
2016Midlife Brain Plasticity: Exercise and Vascular Function1K99HL133449-01 · under PA-15-083TARUMI, TAKASHIUT SOUTHWESTERN MEDICAL CENTER, TX$118,275MTI
2016ER Stress and Protein Dynamics in Cardiac Remodeling1K99HL127302-01A1 · under PA-15-083LAM, MAGGIEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$118,249MTI
2016The role of extracellular adenosine in age-driven susceptibility to S. pneumoniae lung infection1K99AG051784-01 · under PA-15-083BOU GHANEM, ELSATUFTS UNIVERSITY BOSTON, MA$117,628NIA
2016Functional neuroanatomy underlying psychosocial stress-induced cocaine seeking1K99DA039991-01A1 · under PA-15-083MANVICH, DANIEL F.EMORY UNIVERSITY, GA$117,609ZDA1
2016Adaptability and Resilience in Aging Adults (ARIAA)1K99AG052642-01 · under PA-15-083BARTLEY, EMILY J.UNIVERSITY OF FLORIDA, FL$117,488NIA
2016Immune - Microbiota Interaction in defense against Clostridium difficile1K99AI125786-01 · under PA-15-083ABT, MICHAEL C.SLOAN-KETTERING INST CAN RESEARCH, NY$116,905MID
2016Systems approach to define AHR ligand toxicity on reproductive system development1K99ES025280-01A1 · under PA-15-083BUGEL, SEAN MICHAELOREGON STATE UNIVERSITY, OR$116,856ZES1
2016Unique Domain Features of GRK2 and Roles in Cardiovascular Disease1K99HL132882-01 · under PA-15-083SCHUMACHER, SARAH MARIETEMPLE UNIV OF THE COMMONWEALTH, PA$114,574MTI
2016Histone modifications regulating phenotype plasticity: Role of non-canonical Wnt signaling1K99CA208012-01 · under PA-15-083WEBSTER, MARIE RUTHWISTAR INSTITUTE, PA$114,152ZCA1
2016Dissecting mechanism(s) by which ionizing radiation promotes clonal expansion of premalignant cells in the thymus1K99CA212198-01LEE, CHANG-LUNGDUKE UNIVERSITY, NC$113,130NCI
2016High-throughput studies of reassortment and coinfection of influenza viruses1K99AI119401-01A1 · under PA-15-083DIAZ, SAMUEL LNEW YORK UNIVERSITY, NY$112,350MID
2016Epigenetic Mechanisms Controlling T-cell Exhaustion in Prostate Cancer1K99CA197804-01A1 · under PA-15-083KISSICK, HAYDNEMORY UNIVERSITY, GA$111,730NCI
2016Tumor-intrinsic oncogenic alterations and evasion of anti-tumor immunity1K99CA204595-01 · under PA-15-083SPRANGER, STEFANIUNIVERSITY OF CHICAGO, IL$111,690NCI
2016Contributions of Parallel Nigrostriatal Dopamine Circuits to Reward Learning and Habit Formation1K99MH109569-01 · under PA-15-083LERNER, TALIA NEWCOMBESTANFORD UNIVERSITY, CA$111,543ZMH1
2016Dissection of genetic and circuit mechanisms underlying fear memory generalization.1K99MH109652-01 · under PA-15-083RAJASETHUPATHY, PRIYASTANFORD UNIVERSITY, CA$111,543ZMH1
2016Immune Activation and Immunosenescence Biomarkers and Cardiovascular Disease Risk1K99HL129045-01A1 · under PA-15-083OLSON, NELS C.UNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$111,512MCBS
2016Identification and functional characterization of metabolic adaptations during melanoma metastasis1K99CA201228-01A1 · under PA-15-083PISKOUNOVA, ELENAUT SOUTHWESTERN MEDICAL CENTER, TX$109,966NCI
2016Gender Differences in Early Life Adversity: Adult Obesity and Cardiovascular Risk1K99AG052458-01A1LEE, CHIOUNUNIVERSITY OF WISCONSIN-MADISON, WI$109,006NIA
2016Sex- and Smoking- Specific DNA Methylation Signatures of Central Adiposity Change1K99HL130580-01A1 · under PA-15-083JUSTICE, ANNEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$108,460MTI
2016Epigenetic regulation of endothelial phenotype by flow and hypercholesterolemia in vivo and in vitro1K99HL127272-01A1 · under PA-15-083JIANG, YIZHOUUNIVERSITY OF PENNSYLVANIA, PA$108,000MCBS
2016Macrophage-specific function of GWAS CAD-associated LIPA alleles in atherosclerosis1K99HL130574-01 · under PA-15-083ZHANG, HANRUICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$105,322MTI
2016Akt-mediated regulation of endothelial functions1K99HL130581-01 · under PA-15-083LEE, MONICA YYALE UNIVERSITY, CT$104,873MTI
2016MDSC-tumor crosstalk in prostate cancer progression and castration resistance1K99CA194289-01A1 · under PA-15-083WANG, GUOCANUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$104,445NCI
2016Metabolic risk factors for vascular disease throughout the lifespan1K99HD087527-01 · under PA-15-083THOMPSON, JENNIFER ANNEAUGUSTA UNIVERSITY, GA$104,030CHHD
2016Statistical and Computational Methods for Large-Scale Sequencing Studies1K99HL130593-01 · under PA-15-083CHEN, HANHARVARD SCHOOL OF PUBLIC HEALTH, MA$103,680MTI
2016Characterization of recurrent cancer mutations that cause misregulated translation1K99CA204522-01 · under PA-15-083CENIK, CANSTANFORD UNIVERSITY, CA$103,636NCI
2016Targeting BRD4 in Chronic Lymphocytic Leukemia (CLL) Disease Progression to Richter's Transformation (RT)1K99CA208017-01 · under PA-15-083ELGAMAL, DALIAOHIO STATE UNIVERSITY, OH$103,394NCI
2016Desistance from Pathological Drinking Across the Lifespan: A Developmental Analysis1K99AA024236-01A1 · under PA-15-083LEE, MATTHEW RUNIVERSITY OF MISSOURI-COLUMBIA, MO$103,192AA
2016Molecular and Cellular Mechanisms of Neonatal Cardiac Development and Repair1K99HL127295-01A1 · under PA-15-083SERPOOSHAN, VAHIDSTANFORD UNIVERSITY, CA$102,513MTI
2016Vitamin D and colorectal cancer risk: an integrated molecular and genetic epidemiologic study1K99CA207848-01 · under PA-15-083WARREN ANDERSEN, SHANEDAVANDERBILT UNIVERSITY MEDICAL CENTER, TN$102,298NCI
2016Investigation and functional characterization of new drivers of mesenchymal tumorigenesis.1K99CA212200-01GUARNERIO, JLENIABETH ISRAEL DEACONESS MEDICAL CENTER, MA$102,130NCI
2016Lipoprotein Corona Fingerprints: Implications for Pulmonary Clearance and Toxicity of Engineered Nanoparticles1K99ES025813-01A1 · under PA-15-083KONDURU VENKATA, NAGARJUNHARVARD SCHOOL OF PUBLIC HEALTH, MA$101,758ZES1
2016Role of DEAD-box helicase in microRNA biogenesis and Cancer1K99CA197487-01A1 · under PA-15-083HAN, CECILUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$101,631NCI
2016A Novel Prdm14-containing Protein Complex Regulates Chromatin in Stem Cells, Development, and Cancer1K99CA212204-01NADY, NATALIYA HERZANYCHSTANFORD UNIVERSITY, CA$101,536NCI
2016Mapping the conformation-specific interactome of signaling proteins1K99CA203002-01 · under PA-15-083HILL, ZACHARY BENJAMINUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$101,304NCI
2016Exploiting the epithelial-to-mesenchymal transition for the differentiation of cancer stem cells1K99CA201574-01A1 · under PA-15-083PATTABIRAMAN, DIWAKAR RWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$101,116NCI
2016Mesenchymal Stem Cells as Determinants of Tissue Aging1K99AG053438-01 · under PA-15-083WOSCZYNA, MICHAELSTANFORD UNIVERSITY, CA$100,834NIA
2016Epigenetic Regulation of Longevity in Response to Environmental Signals1K99AG051738-01A1 · under PA-15-083BOOTH, LAUREN NICOLESTANFORD UNIVERSITY, CA$100,466NIA
2016Retinoic Acid Signaling Disruption by Phthalates in Human and Rodent Fetal Testis1K99ES025231-01A1 · under PA-15-083SPADE, DANIEL JAMESBROWN UNIVERSITY, RI$100,210ZES1
2016The Role of the Homeoprotein Vax1 in Fertility and Circadian Rhythm1K99HD084759-01A1 · under PA-15-083HOFFMANN, HANNE MUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$100,192CHHD
2016Spatio-Temporal Signaling Dynamics in Neuronal Cell Fate Decision and Patterning1K99HD087532-01 · under PA-15-083LI, PULINCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$100,000CHHD
2016Dissect regulation of RNA translation in human cancers1K99CA207865-01 · under PA-15-083JI, ZHEHARVARD MEDICAL SCHOOL, MA$99,943NCI
2016Rehabilitation strategies for independent central binocular scotomas1K99EY026130-01 · under PA-15-083ALBERTI, CONCETTA FRANCESCANORTHEASTERN UNIVERSITY, MA$99,592ZEY1
2016Deconstructing the Tumor Microenvironment and its Contribution to Metastasis1K99CA201304-01 · under PA-15-083RAFAT, MARJANSTANFORD UNIVERSITY, CA$99,550NCI
2016Mechanisms of Dendrite Regeneration after Injury1K99NS097627-01 · under PA-15-083THOMPSON-PEER, KATHERINE LOUISEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$98,384NST
2016Properties of photoreceptors and Muller cells investigated with AO-OCT1K99EY026068-01 · under PA-15-083JONNAL, RAVI S.UNIVERSITY OF CALIFORNIA AT DAVIS, CA$97,834ZEY1
2016Engineering the Cancer Microenvironment1K99CA198929-01A1 · under PA-15-083SOLORIO, LUISUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$97,467NCI
2016Investigating the Impact of Person-Centered Home-Based Palliative Care on Providers1K99AG052647-01A1COULOURIDES KOGAN, ALEXIS MARIEUNIVERSITY OF SOUTHERN CALIFORNIA, CA$97,362NIA
2016Host Innate Immune Response as a Barrier to Cross-Species Retrovirus Transmission1K99AI125136-01A1 · under PA-15-083SHARMA, AMITFRED HUTCHINSON CANCER RESEARCH CENTER, WA$97,038AIDS
2016Ciliary Calcium Signaling and Cardiac Left-Right Asymmetry1K99HD086274-01A1 · under PA-15-083YUAN, SHIAULOUYALE UNIVERSITY, CT$96,507CHHD
2016Role of perivascular nerves and vascular dysfunction in inflammatory bowel disease1K99HL129196-01A1 · under PA-15-083BOERMAN, ERIKA MARYUNIVERSITY OF MISSOURI-COLUMBIA, MO$96,097MTI
2016Cognitive and Neural Moderators of Longitudinal Decline in Frontotemporal Degeneration1K99AG056054-01 · under PA-15-083MASSIMO, LAUREN MPENNSYLVANIA STATE UNIVERSITY, THE, PA$96,066NRRC
2016IMAGING FOR ASSESSMENT AND PREDICTION OF RESPONSE TO THERAPY FOR TRIPLE NEGATIVE BREAST CANCER1K99CA201601-01 · under PA-15-083MARQUEZ-NOSTRA, BERNADETTEWASHINGTON UNIVERSITY, MO$95,705NCI
2016Improved imaging of deep brain nuclei with 7 Tesla MRI using comprehensive magnetic field monitoring and compensation1K99EB021349-01A1 · under PA-15-083STOCKMANN, JASON PMASSACHUSETTS GENERAL HOSPITAL, MA$95,040ZEB1
2016Inhibitory control of a hypothalamic circuit for aggression1K99MH109674-01A1FALKNER, ANNEGRET LEANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$94,890ZMH1
2016ASSESSMENT OF RETINAL FUNCTION IN HEALTH AND DISEASE FROM MOUSE TO HUMAN1K99EY026651-01 · under PA-15-083VINBERG, FRANSWASHINGTON UNIVERSITY, MO$94,826ZEY1
2016Patient-adjustable MRI technology for high-resolution imaging of deep brain stimulation1K99EB021320-01A1 · under PA-15-083GOLESTANI RAD, LALEHMASSACHUSETTS GENERAL HOSPITAL, MA$94,586ZEB1
2016Identifying mechanisms of deregulated mTORC1 activity during skeletal muscle atrophy1K99AR069109-01A1 · under PA-15-083COMB, WILLIAMWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$94,392AMS

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