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NIH funding notice PA-16-193

NIH Pathway to Independence Award (Parent K99/R00)

Closed on January 24, 2018.

Posted
April 15, 2016
Close date
January 24, 2018
Activity codes
K99, R00
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-16-077 NIH Pathway to Independence Award (Parent K99/R00)
  2. 2 steps back: PA-15-083 NIH Pathway to Independence Award (Parent K99/R00)
  3. 3 steps back: PA-14-042 NIH Pathway to Independence Award (Parent K99/R00)
  4. 4 steps back: PA-11-197 NIH Pathway to Independence Award (Parent K99/R00)
  5. 5 steps back: PA-10-063 NIH Pathway to Independence Award (Parent K99/R00)
  6. 6 steps back: PA-09-036 NIH Pathway to Independence Award (K99/R00)
  7. 7 steps back: PA-07-297 NIH Pathway to Independence (PI) Award (K99/R00)
  8. 8 steps back: PA-06-133

Replaced by PA-18-397, PA-18-398.

Who won it before

1,155 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $128,006,841 in first-year total cost, median $103,464.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I]182
  2. NST-2 Study Section [NST-2]55
  3. Basic Neuroscience of Aging Study Section[NIA-N]42
  4. NHLBI Mentored Transition to Independence Study Section[MTI (JA)]40
  5. Special Emphasis Panel[ZGM1 TWD-A (KR)]35

Most frequent institutions

  1. STANFORD UNIVERSITY94
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO49
  3. MASSACHUSETTS GENERAL HOSPITAL38
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGO30
  5. JOHNS HOPKINS UNIVERSITY28
Competing awards under PA-16-193 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019High-throughput optical investigation into intact large-scale nervous systems for Alzheimers disease1K99AG059946-01REN, JIANMASSACHUSETTS GENERAL HOSPITAL, MA$137,160NIA
2019Role of Nucleus Accumbens D2-expressing Neurons in Punished Cocaine Seeking1K99DA044331-01A1VENTO, PETER J.MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$137,040ZDA1
2019Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation1K99DA046564-01HEBERT, EMILY TAYLORUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$92,213ZDA1
2019Association of blood-brain barrier breakdown with structural and molecular neuropathology in early Alzheimer's disease1K99AG057797-01A1REAS, EMILIE T.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$87,704NIA
2018Defining the role of cortical circuit dynamics in learning and addiction1K99DA045103-01SICILIANO, CODYMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$182,790ZDA1
2018Transcranial Magnetic Stimulation and Tobacco Use Disorder: A Network-Level Approach with Attention to Sex as a Biological Variable1K99DA045749-01PETERSEN, NICOLEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$182,401ZDA1
2018Prefrontal Pathways Engaged in Excessive Alcohol Consumption1K99AA024507-01A1 · under PA-15-083SALLING, MICHAEL CHARLESCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$180,651AA
2018Alcohol-related sleep disturbances and circuit dynamics of arousal neuropeptides1K99AA025677-01A1GIARDINO, WILLIAM JSTANFORD UNIVERSITY, CA$180,263AA
2018Molecular imaging-directed bioengineering of nanoconjugates as adaptable tumor targeting platforms1K99CA215301-01A1OBAID, GIRGISMASSACHUSETTS GENERAL HOSPITAL, MA$179,280ZCA1
2018Marine Omega-3 Polyunsaturated Fatty Acid, Gut Microbiome, and Colorectal Cancer Prevention1K99CA215314-01A1SONG, MINGYANGMASSACHUSETTS GENERAL HOSPITAL, MA$179,082NCI
2018A novel role for the medial amygdala in the modulation of sex differences in cocaine reward1K99DA042100-01A1WALKER, DEENA M.ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$177,930ZDA1
2018Engineering CRISPR constructs to elucidate the causal contribution of cell-type specific, gene-targeted CREB binding to the pathogenesis of drug abuse1K99DA045795-01HAMILTON, PETER JAMESICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$177,770ZDA1
2018Understanding Implications of Genetic Attributions for Addiction1K99HG010084-01LEBOWITZ, MATTHEWNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$166,646ZRG1
2018Quantitative Imaging Biomarkers of Treatment Response and Prognosis in Breast Cancer1K99CA218667-01A1WU, JIASTANFORD UNIVERSITY, CA$160,852NCI
2018To Reach Unrestricted Services for Transgender Women (TRUST)1K99DA046311-01CYRUS, ELENAFLORIDA INTERNATIONAL UNIVERSITY, FL$159,494ZDA1
2018Mediator complex in cardiac development and function1K99HL143210-01FANG, XIUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$156,924MTI
2018Protective Effects of Amlexanox Against Atherosclerosis1K99HL143277-01ZHAO, PENGUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$156,924MTI
2018Inferring the roots of metastases and their effects on patient survival1K99CA229991-01REITER, JOHANNES GSTANFORD UNIVERSITY, CA$154,629NCI
2018Macrophage Metabolism After Target Cell Ingestion Regulates Anti-Inflammatory Reprogramming1K99HL141658-01MCCUBBREY, ALEXANDRA LEIGHNATIONAL JEWISH HEALTH, CO$154,319MTI
2018Molecular basis for ligand and cell type specific regulation of opioid receptors1K99DA043607-01A1LOBINGIER, BRADENUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$153,630ZDA1
2018General and Minority-related Risk and Protective Factors for, and Consequences of, Alcohol Use among Latino College Students1K99AA025998-01A1ARMENTA, BRIAN ERIKUNIVERSITY OF MISSOURI-COLUMBIA, MO$148,805AA
2018Transcriptional control by the epigenetic reader ENL in human cancer1K99CA226399-01WAN, LILINGROCKEFELLER UNIVERSITY, NY$146,963NCI
2018Discovery and Characterization of Genetic Mechanisms Driving Stress-induced Addiction Vulnerability1K99DA043573-01A1DICKSON, PRICE EVANSJACKSON LABORATORY, ME$144,284ZDA1
2018The effect of systemic hypertension on prognosis of myocardial infarction: Understanding, prediction and therapy evaluation1K99HL138288-01A1AVAZMOHAMMADI, REZAUNIVERSITY OF TEXAS AT AUSTIN, TX$141,242MTI
2018Translational Regulation by RNA Regulating Proteins in Leukemia1K99CA229993-01VU, LY PSLOAN-KETTERING INST CAN RESEARCH, NY$140,859NCI
2018Defining the molecular determinants of mesenchymal lineage allocation in lung development and disease1K99HL141684-01ZEPP, JARODUNIVERSITY OF PENNSYLVANIA, PA$140,357MTI
2018Direct and Mediating Pathways Linking Personal Networks with Cardiovascular Disease1K99AG059950-01CHILD, STEPHANIEUNIVERSITY OF CALIFORNIA BERKELEY, CA$139,439NIA
2018Social Media Use and Depression Outcomes among U.S. Lesbian, Gay, and Bisexual Young Adults1K99MD012813-01ESCOBAR-VIERA, CÉSAR GABRIELUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$137,542ZMD1
2018Elucidating the Contextual Roles of IL-10 in Patient Response to Cancer Immunotherapy1K99CA230201-01WOODS, DAVID MICHAELNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$137,216NCI
2018Understanding the highly divergent mitochondrial ATP synthase in T. gondii1K99AI137218-01HUET, DIEGOWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$137,160MID
2018Unraveling the mechanisms of microhemorrhages in cerebral amyloid angiopathy; from ex vivo MRI in humans to in vivo optics in mice1K99AG059893-01VAN VELUW, SUSANNE JANNEKEMASSACHUSETTS GENERAL HOSPITAL, MA$136,360NIA
2018Exploring the role of LHFPL5-associated proteins and Ca2+-binding proteins in hair cell mechanotransduction1K99DC016328-01A1WU, ZIZHENJOHNS HOPKINS UNIVERSITY, MD$136,147CDRC
2018Mechanistic and functional dissection of myeloid blood cancers1K99HL136924-01A1ELF, SHANNON ELISABETHBRIGHAM AND WOMEN'S HOSPITAL, MA$135,540MTI
2018Place-level discrimination and birth outcomes1K99MD012615-01NGUYEN, THUUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$135,437ZMD1
2018Cellular mechanisms and therapeutic possibilities of inhibiting oncogenic KRAS1K99CA226363-01WOLFE, ANDREW LUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$135,108NCI
2018Integrative framework for identifying dysregulated mechanisms in the tumor-immune microenvironment1K99CA230195-01AZIZI, ELHAMSLOAN-KETTERING INST CAN RESEARCH, NY$134,632NCI
2018Trans-Tympanic Drug Delivery for Treatment and Prophylaxis of Otitis Media1K99DC016644-01A1YANG, RONGBOSTON CHILDREN'S HOSPITAL, MA$134,322CDRC
2018Structural and Mechanistic Elucidation of NAIP/NLRC4 Inflammasomes in Innate Immunity1K99AI137300-01ZHANG, LIMANBOSTON CHILDREN'S HOSPITAL, MA$134,017AITC
2018Molecular and pathogenic study of an oral TM7 strain, the first cultivated ultra-small bacterium1K99DE027719-01BOR, BATBILEGADA FORSYTH INSTITUTE, INC., MA$134,001DSR
2018Development of a strategy for endocrine axis discovery1K99HL138193-01A1SELDIN, MARCUS MICHAELUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$134,001MTI
2018Human cerebral organoids as a model system for neural development and disease1K99HD096105-01WATANABE, MOMOKOUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$134,001CHHD
2018Millisecond resolution statistics of cortical populations1K99EY028612-01A1DENMAN, DANIEL JAMESALLEN INSTITUTE, WA$132,984ZEY1
2018Investigating functional sites in protein kinases as targets for cancer mutations and novel drugs1K99CA226396-01CREIXELL, PAUMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$132,927NCI
2018Investigation of the role of Turner syndrome on approximate number sense1K99HD092883-01A1BAKER, JOSEPHSTANFORD UNIVERSITY, CA$132,867CHHD
2018Toll-like receptors and respiratory microbiota interactions in idiopathic pulmonary fibrosis1K99HL139996-01O'DWYER, DAVID NOELUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$132,300MTI
2018Dissecting and reconstructing the molecular roadmaps of cellular reprogramming to iPSCs in single-cell resolution1K99HD096049-01SHU, JIANBROAD INSTITUTE, INC., MA$132,300CHHD
2018Genetic and Biochemical Interrogation of Rotavirus-Cohesin Interaction1K99AI135031-01A1DING, SIYUANSTANFORD UNIVERSITY, CA$132,219MID
2018SRPK1 regulation of the protamine-to-histone exchange in early embryonic development1K99HD094901-01GOU, LANTAOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$131,990CHHD
2018Addressing Provider Stress and Unconscious Bias to Improve Quality of Maternal Health Care1K99HD093798-01A1AFULANI, PATIENCE AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$131,647CHHD
2018Mechanisms by Which Alcohol-Induced Dysbiosis Impairs Host Defense Against Klebsiella Pneumoniae1K99AA026336-01SAMUELSON, DERRICK RLSU HEALTH SCIENCES CENTER, LA$131,333AA
2018Generalizing polygenic risk prediction methods across populations for insights into psychiatric disease1K99MH117229-01MARTIN, ALICIAMASSACHUSETTS GENERAL HOSPITAL, MA$130,786ZMH1
2018The role of hyaluronan in age-related vascular and skeletal muscle dysfunction1K99AT010017-01MACHIN, DANIEL ROBERTUNIVERSITY OF UTAH, UT$130,540ZAT1
2018Regulation of antiviral immunity at barrier surfaces by interleukin-1 family cytokines1K99AI130258-01A1ORZALLI, MEGAN HORNBOSTON CHILDREN'S HOSPITAL, MA$130,478AITC
2018Role of the Rett Syndrome-causing gene MeCP2 in 3D chromosomal organization and rescue of cellular disease phenotypes1K99MH113813-01A1LIU, X. SHAWNWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$130,464ZMH1
2018Phrenic Afferents and Neuromuscular Plasticity Following Spinal Cord Injury1K99HL143207-01STREETER, KRISTI ANNUNIVERSITY OF FLORIDA, FL$130,194MTI
2018The role of SMAD1 and SMAD5 in hormonal response, endometrial receptivity and glandular function1K99HD096057-01MONSIVAIS, DIANABAYLOR COLLEGE OF MEDICINE, TX$129,955CHHD
2018ARF6 function in cancers driven by RAS hyperactivation1K99CA230312-01YOO, JAE HYUKUNIVERSITY OF UTAH, UT$129,824NCI
2018Inorganic polyphosphate as a chaperone in aging and in neurodegenerative diseases1K99AG055701-01A1SOLESIO TORREGROSA, MARIA DE LA ENCARNACIONNEW YORK UNIVERSITY, NY$129,177NIA
2018The role of palmitoylation in cardiac signal transduction and disease pathogenesis1K99HL136695-01A1BRODY, MATTHEW JACOBCINCINNATI CHILDRENS HOSP MED CTR, OH$129,060MTI
2018The role of Corticotrophin Releasing Hormone on placental transcriptional networks and birth timing1K99HD096112-01PAQUETTE, ALISON GENEVIEVEINSTITUTE FOR SYSTEMS BIOLOGY, WA$129,052CHHD
2018Hepatocyte-derived MIF: a key contributor to Alcoholic Liver Disease1K99AA026648-01A1POULSEN, KYLECLEVELAND CLINIC LERNER COM-CWRU, OH$128,967AA
2018The role of Fusobacterium in colorectal cancer treatment, tumor ecology and chemotherapeutic efficacy1K99CA229984-01BULLMAN, SUSANDANA-FARBER CANCER INST, MA$128,963NCI
2018Identification of neural mechanisms linking autism-risk gene disruptions with impaired social behavior1K99MH115143-01A1CHOE, KATRINAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$128,601ZMH1
2018Precarious Employment as a Determinant of Overweight and Cardiometabolic Risk1K99MD012807-01ODDO, VANESSA MARIEUNIVERSITY OF WASHINGTON, WA$128,169ZMD1
2018Development of neural processing of sound in infancy1K99DC016640-01A1LAU, BONNIE K.UNIVERSITY OF WASHINGTON, WA$128,083CDRC
2018Accelerating the diagnosis of bipolar disorder using genetic and phenotypic signatures1K99MH116115-01OLDE LOOHUIS, LOES MARLEINUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$128,072ZMH1
2018Characterizing the mechanisms behind the association between purpose in life and health1K99AG055696-01A1KIM, ERICHARVARD SCHOOL OF PUBLIC HEALTH, MA$127,845NIA
2018Developmental and evolutionary basis of neuronal diversity1K99EY029356-01KONSTANTINIDES, NIKOLAOSNEW YORK UNIVERSITY, NY$127,737ZEY1
2018Hyperpolarized Micro-NMR for Quantitative Analysis of Metabolism in Leukemia Stem Cells1K99CA226357-01JEONG, SANGMOOSLOAN-KETTERING INST CAN RESEARCH, NY$127,563NCI
2018The Automatic Context Measurement Tool: bringing environmental data to non-specialists1K99LM012868-01MOONEY, STEPHEN JOHNUNIVERSITY OF WASHINGTON, WA$127,305ZLM1
2018Induced host immune response to HIV-1 after antibody therapy1K99AI129739-01A1VON BOEHMER, LOTTASTANFORD UNIVERSITY, CA$127,035AIDS
2018Functional characterization of the Alzheimer's disease epigenome1K99AG059918-01CORCES, MICHAEL RYANSTANFORD UNIVERSITY, CA$127,035NIA
2018Linking emotion, motivation and action with amygdalo-nigro-striatal circuits1K99MH116065-01STEINBERG, ELIZABETH EUGENIASTANFORD UNIVERSITY, CA$126,827ZMH1
2018Causal mechanisms of distributed brain network function during episodic memory retrieval1K99MH117226-01BRAGA, RODRIGO MSTANFORD UNIVERSITY, CA$126,819ZMH1
2018Molecular mechanisms of weak communication signal transduction1K99DC016658-01LEITCH, DUNCAN BUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$126,580CDRC
2018Metabolic Constraints on Cancer Cell Proliferation1K99CA218679-01A1SULLIVAN, LUCAS BRYANMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$126,503NCI
2018Investigating immune-microbiota interaction in lung cancer1K99CA226400-01JIN, CHENGCHENGMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$126,225ZCA1
2018Brain pericyte contractility, cerebral blood flow and blood-brain barrier integrity are impaired by normal aging and Alzheimer's disease amyloid-beta and are dependent on p75NTR1K99AG058780-01A1NELSON, AMY RUNIVERSITY OF SOUTHERN CALIFORNIA, CA$126,225NIA
2018Role of Dopamine and Basal Ganglia Circuits in Integrating Costs and Benefits for Action1K99MH116116-01DONAHUE, CHRISTOPHER HJ. DAVID GLADSTONE INSTITUTES, CA$125,928ZMH1
2018Health Reform and Oral Health Disparities: a Mixed Methods Evaluation1K99MD012253-01A1ELANI, HAWAZIN WHARVARD MEDICAL SCHOOL, MA$125,646ZMD1
2018Spatiotemporal Risk Assessment Modeling of Chemical Mixtures1K99ES029523-01MESSIER, KYLE PHILIPOREGON STATE UNIVERSITY, OR$125,066ZES1
2018ATHEROSCLEROTIC LESION INITIATION BY RESIDENT AORTIC MACROPHAGE PROLIFERATION AND LIPID UPTAKE1K99HL138163-01A1WILLIAMS, JESSE WARRENWASHINGTON UNIVERSITY, MO$124,519MTI
2018IGF-1 Regulation of Astrocyte Mitochondrial Metabolism and Redox Homeostasis in Brain Aging1K99AG056662-01A1LOGAN, SREEMATHIUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$124,200NIA
2018New approach for cholesterol and sphingolipid reduction in Niemann-Pick C1 disease1K99HD096117-01NEWTON, JASON CHARLESVIRGINIA COMMONWEALTH UNIVERSITY, VA$124,016CHHD
2018Structural and Pharmacological Study of the KCNQ1/KCNE1 Potassium Channel Complex1K99HL143037-01SUN, JIROCKEFELLER UNIVERSITY, NY$122,783MTI
2018A differentiated care model to improve the efficiency of PrEP delivery in Kenya1K99MH118134-01MUGWANYA, KENNETH KIGGUNDUUNIVERSITY OF WASHINGTON, WA$122,769ZMH1
2018Virtual prototyping for retinal prosthesis patients1K99EY029329-01BEYELER, MICHAELUNIVERSITY OF WASHINGTON, WA$122,763ZEY1
2018GAZE AND THE VISUAL CONTROL OF FOOT PLACEMENT WHEN WALKING OVER ROUGH TERRAIN1K99EY028229-01A1MATTHIS, JONATHAN SAMIRUNIVERSITY OF TEXAS AT AUSTIN, TX$121,770ZEY1
2018Engaging Social Support to Prevent High-Risk Drinking and Posttraumatic Stress After Sexual Assault: Developing and Testing a Web-Based Intervention1K99AA026317-01A1DWORKIN, EMILY RAPHAELUNIVERSITY OF WASHINGTON, WA$121,431AA
2018Modeling of subcellular signaling crosstalk in failing myocytes1K99HL138160-01A1MOROTTI, STEFANOUNIVERSITY OF CALIFORNIA AT DAVIS, CA$121,328MTI
2018Mechanisms regulating afferent innervation in the dental pulp1K99DE027706-01PETERS, SARAHUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$121,041DSR
2018The Role of Retrotransposon Activity in Mammalian Pre-Implantation Development1K99HD096108-01MODZELEWSKI, ANDREW JOSEPHUNIVERSITY OF CALIFORNIA BERKELEY, CA$120,960CHHD
2018Age effects on memory and reward systems in decision making1K99AG058748-01BERRY, ANNE SHIVELYUNIVERSITY OF CALIF-LAWRENC BERKELEY LAB, CA$120,878NIA
2018Uncovering roles of polyunsaturated fatty acids in pancreatic cancer etiology1K99CA218892-01A1WU, LANGVANDERBILT UNIVERSITY MEDICAL CENTER, TN$120,472NCI
2018Spatial patterning modulates tissue revascularization and regeneration1K99HL136701-01A1NAKAYAMA, KARINASTANFORD UNIVERSITY, CA$120,334MTI
2018Learning the rules of enhancer activity to understand non-coding genetic variation in autoimmune disease1K99HG009920-01DE BOER, CARLBROAD INSTITUTE, INC., MA$120,204GNOM
2018Discovery of Novel Epigenetic Regulators of Heart Failure in a Panel of Mice1K99HL138301-01A1RAU, CHRISTOPH DANIELUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$119,648MTI
2018Perceptual stability during torsional eye movements1K99EY027846-01A1OTERO-MILLAN, JORGEJOHNS HOPKINS UNIVERSITY, MD$119,628ZEY1
2018Neural Basis of Social Cognition Deficits in Youth With Autism and Schizophrenia1K99MH113820-01A1NAIR, AARTIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$118,761ZMH1
2018Integrating 'omics', evolution, and structural biochemistry to understand animal fertilization1K99HD090201-01A1WILBURN, DAMIEN BEAUUNIVERSITY OF WASHINGTON, WA$118,329CHHD
2018Regulation of VGLUT2 in aging-related neurodegenerative disorders1K99AG059834-01STEINKELLNER, THOMASUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$117,947NIA
2018Mechanisms of Nuclear Body Formation in the Early Embryo1K99HD092625-01A1RIEDER, LEILA ELIZABETHBROWN UNIVERSITY, RI$117,658CHHD
2018Understanding the developmental mechanisms that ensure robustness in neuronal patterning1K99HD096050-01SHAH, PAVAK KIRITSLOAN-KETTERING INST CAN RESEARCH, NY$117,044CHHD
2018Capacity limits in the neural circuitry of visual word recognition1K99EY029366-01WHITE, ALEXANDER LINDLEYUNIVERSITY OF WASHINGTON, WA$116,290ZEY1
2018Early epigenetic footprint of neurological diseases1K99MH117393-01KREIMER, ANATUNIVERSITY OF CALIFORNIA BERKELEY, CA$115,560ZMH1
2018Leptin, a therapeutic avenue for the treatment of vascular disease, focus on congenital and antiretroviral therapy-associated lipodystrophies1K99HL140139-01A1BRUDER, THIAGOAUGUSTA UNIVERSITY, GA$115,506MTI
2018Genetic and Epigenetic Strategies for the Acquisition of Telomere Maintenance in Human Cancer Cells1K99CA226387-01BARTHEL, FLORISJACKSON LABORATORY, ME$115,407NCI
2018Early-Life Health Consequences of Unequal Kinship Networks1K99HD096322-01SOHN, HEEJUUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$115,371CHHD
2018Analysis of the Molecular Machinery Regulating Gene Expression during Vertebrate Development1K99HD093873-01BEAUDOIN, JEAN-DENISYALE UNIVERSITY, CT$115,350CHHD
2018Chronic ethanol effects on cholinergic interneurons of the striatum1K99AA025991-01A1SALINAS, ARMANDOGEORGE MASON UNIVERSITY, VA$115,220AA
2018Investigating the regulation of mitochondrial heterogeneity and metastasis in melanoma1K99CA222617-01LUO, CHIDANA-FARBER CANCER INST, MA$114,481NCI
2018Role of DNA sensing pathways in KSHV associated cancers1K99CA230178-01MA, ZHEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$113,624NCI
2018Integrating multidimensional genomic data to discover clinically-relevant predictive models1K99HG009678-01A1LASSEIGNE, BRITTANY NICOLEHUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY, AL$112,117GNOM
2018Investigating how signaling via adhesion GPCR Latrophilins regulates synapse formation and specificity in the hippocampus1K99MH117235-01SANDO, RICHARD CHESLOCKSTANFORD UNIVERSITY, CA$111,098ZMH1
2018A Model Based Approach to Individualizing Antimicrobial Dosing in Pediatric Sepsis1K99HD096123-01ZANE, NICOLE RCHILDREN'S HOSP OF PHILADELPHIA, PA$110,560CHHD
2018Delineating neurobiological heterogeneity in internalizing symptoms using machine learning and deep phenotyping1K99MH117274-01KACZKURKIN, ANTONIAUNIVERSITY OF PENNSYLVANIA, PA$109,900ZMH1
2018Circuitry Mechanisms of Enhanced Visual Plasticity During Locomotion1K99EY029002-01SUN, YUJIAO JENNIFERUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$109,892ZEY1
2018Cellular and Physical Mechanisms of Developmental Symmetry1K99HD092582-01A1XIONG, FENGZHUBRIGHAM AND WOMEN'S HOSPITAL, MA$109,490CHHD
2018Lincenc1 regulates the lipopolysaccharide-induced inflammatory response in macrophages1K99HL141685-01ZHANG, DUOBOSTON UNIVERSITY MEDICAL CAMPUS, MA$109,296MTI
2018Dedicator of cytokinesis 2 in atherosclerosis1K99HL141583-01GUO, XIAUNIVERSITY OF GEORGIA, GA$108,853MTI
2018Using Legionella-amoeba co-evolution to reveal new modes of immunity and pathogenesis1K99AI139344-01LEVIN, TERA CATHERINEFRED HUTCHINSON CANCER RESEARCH CENTER, WA$108,648MID
2018Exploring Mechanisms of Pathogenicity in C9ORF72 Frontotemporal Dementia and Amyotrophic Lateral Sclerosis1K99AG057808-01A1BURBERRY, AARONHARVARD UNIVERSITY, MA$108,454NIA
2018Investigation of subtelomeric gene families in Cryptosporidium1K99AI137442-01SATERIALE, ADAMUNIVERSITY OF PENNSYLVANIA, PA$108,000MID
2018Cocaine-induced plasticity of D2 receptor synapses1K99DA044287-01A1ROBINSON, BROOKS GOREGON HEALTH & SCIENCE UNIVERSITY, OR$107,950ZDA1
2018Utilizing Precision Medicine to elucidate the mechanisms underpinning treatment efficacy1K99CA230384-01HOPKINS, BENJAMIN D.WEILL MEDICAL COLL OF CORNELL UNIV, NY$107,860NCI
2018Uncovering the molecular identity of retinal cell types, and their responses to nerve injury using single-cell transcriptomics1K99EY028625-01SHEKHAR, KARTHIKBROAD INSTITUTE, INC., MA$107,618ZEY1
2018Role of Angiotensin II and Chronic Inflammation in Persistent Microvascular Dysfunction Following Preeclamptic Pregnancy1K99HL138133-01A1STANHEWICZ, ANNAPENNSYLVANIA STATE UNIVERSITY, THE, PA$106,737MTI
2018DNA Methylation and Vascular Function in Obesity: Role of Exercise and Weight Loss1K99HL140049-01MOHAMED, ABEER MUNIVERSITY OF ILLINOIS AT CHICAGO, IL$106,320MTI
2018Role of top-down feedback in visual perception1K99EY029374-01NURMINEN, LAURIUNIVERSITY OF UTAH, UT$106,064ZEY1
2018Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failure1K99HL141678-01HARHAY, MICHAEL OSCARUNIVERSITY OF PENNSYLVANIA, PA$105,743MTI
2018Evaluation of PARP1 targeted imaging as screening tool for esophageal adenocarcinoma1K99CA218875-01A1KOSSATZ, SUSANNESLOAN-KETTERING INST CAN RESEARCH, NY$105,629NCI
2018Role of Lateral Hypothalmic Area Perineuronal Nets in the Reinstatement of Cocaine-Seeking Behavior1K99DA045082-01A1BLACKTOP, JORDAN MICHAELWASHINGTON STATE UNIVERSITY, WA$105,585ZDA1
2018Effects of Functional Food Diets on Cardiometabolic and Metabolomics Profiles in Minority Youth1K99MD012815-01DHILLON, JAAPNAUNIVERSITY OF CALIFORNIA, MERCED, CA$105,359ZMD1
2018Extracellular Vesicles as a Link Between Placental and Renal Dysfunction in Preeclampsia1K99HD096125-01PANTHAM, PRIYADARSHINIUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$104,534CHHD
2018Prefontal Microcircuits Underlying Cognitive Flexibility1K99MH117271-01SPELLMAN, TIMOTHYWEILL MEDICAL COLL OF CORNELL UNIV, NY$103,628ZMH1
2018Modeling Preeclampsia Using Human Pluripotent Stem Cells1K99HD091452-01A1HORII, MARIKOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$103,589ZHD1
2018A Mobile Health Intervention to Reduce Diabetes Disparities in Chinese Americans1K99MD012811-01HU, LUNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$103,366ZMD1
2018Role of skeletal muscle mitophagy in healthy aging1K99AG057825-01A1DRAKE, JOSH CUNIVERSITY OF VIRGINIA, VA$103,289NIA
2018Vascular Pannexin 1 in Ischemic Stroke1K99HL143165-01GOOD, MIRANDA EUNIVERSITY OF VIRGINIA, VA$103,151MTI
2018Defining miR-223-dependent mechanisms regulating hematopoietic stem cell production from endothelium1K99HL141687-01KASPER, DIONNAYALE UNIVERSITY, CT$102,716MTI
2018Altered mRNA splicing dependent on mutant p53 identifies novel therapeutic vulnerability in pancreatic cancer1K99CA226342-01ESCOBAR HOYOS, LUISASLOAN-KETTERING INST CAN RESEARCH, NY$102,057NCI
2018Macrophage inflammasome activation and the mechanism of lipolysis resistance in aged adipose1K99AG058800-01A1CAMELL, CHRISTINAYALE UNIVERSITY, CT$101,499NIA
2018Identification of a novel pathway that regulates optic nerve myelination and remyelination1K99EY029330-01SUN, LUSTANFORD UNIVERSITY, CA$101,400ZEY1
2018Mechanisms of Lifespan Regulation by Sirt6 in Drosophila melanogaster1K99AG057812-01TAYLOR, JACKSON RICHARDBROWN UNIVERSITY, RI$101,281NIA
2018Quantifying the sources and dynamics of tumor growth variability using Tuba-seq1K99CA226506-01MCFARLAND, CHRISTOPHER DENNISSTANFORD UNIVERSITY, CA$101,177NCI
2018Molecular Genetic Examination of Co-Occurring Learning Disabilities1K99HD094902-01TRUONG, DONGNHU TYALE UNIVERSITY, CT$100,882CHHD
2018The racial disparity in platelet PAR4 signaling enhances thrombus formation1K99HL136784-01A1TOURDOT, BENJAMIN ERICUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$100,767MTI
2018Data-driven approaches to identify biomarkers and regulators of cancer drug resistance1K99CA218900-01A1JIANG, PENGDANA-FARBER CANCER INST, MA$100,000NCI
2018Functional consequences of sensory neuronal invasion in oral cancer pain and carcinogenesis1K99DE028019-01SCHEFF, NICOLE NNEW YORK UNIVERSITY, NY$99,855DSR
2018Elucidating AHR signaling interplay in orofacial clefting and endocrine disruption using microplate microfluidics1K99ES028744-01A1JOHNSON, BRIAN P.UNIVERSITY OF WISCONSIN-MADISON, WI$99,786ZES1
2018The Role of Leiomodin1 in Vascular Disease1K99HL136865-01A1NANDA, VIVEKSTANFORD UNIVERSITY, CA$99,483MTI
2018Mechanisms to predict and potentiate acupuncture analgesia in sickle cell disease1K99AT010012-01WANG, YINGUNIVERSITY OF MINNESOTA, MN$99,195ZAT1
2018Studying methionine flux and its role in aging and neurodegeneration1K99AG057792-01PARKHITKO, ANDREY AHARVARD MEDICAL SCHOOL, MA$98,754NIA
2018Defining Direct and Indirect Roles of Nodal Signaling in Convergence & Extension1K99HD091386-01A1WILLIAMS, MARGOT L.K.WASHINGTON UNIVERSITY, MO$98,736CHHD
2018Social Influence Strategies during a Web-based Smoking Prevention Intervention for Adolescents1K99DA044277-01A1KHALIL, GEORGES ELIASUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$98,541ZDA1
2018A Multilevel Approach to Cardiovascular Health in African American Breast Cancer Survivors: from Neighborhoods to Metabolomics1K99MD013300-01A1QIN, BORBHS -CANCER INSTITUTE OF NEW JERSEY, NJ$98,481ZMD1
2018Defining the role of metabolic heterogeneity in melanoma dissemination and therapy escape1K99CA226679-01SMALLEY, INNAH. LEE MOFFITT CANCER CTR & RES INST, FL$98,371NCI
2018New mechanisms of acquired resistance to EGFR-TKIs in Non-small-cell lung cancer1K99CA215316-01A1HE, JUNTHOMAS JEFFERSON UNIVERSITY, PA$98,086NCI
2018Determinants of type-dependent retinal ganglion cell resilience: potential targets for neuroprotection and axon regeneration1K99EY029360-01TRAN, NICHOLAS MINH ABELLHARVARD UNIVERSITY, MA$97,783ZEY1
2018Synaptic and intrinsic mechanisms underlying visual cortical enhancement following retinal inactivation1K99EY029326-01FONG, MING-FAIMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$97,650ZEY1
2018Couples' Interactions and Inflammatory Responses: The Context-Dependent Role of Age1K99AG056667-01A1WILSON, STEPHANIE JOYOHIO STATE UNIVERSITY, OH$97,465NIA
2018Multidimensional cell recording with single-cell genomics1K99HG010152-01MCKENNA, AARON HUNIVERSITY OF WASHINGTON, WA$97,443GNOM
2018ER stress-induced translational regulation in retinal degeneration1K99EY029013-01VASUDEVAN, DEEPIKANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$97,200ZEY1
2018Innate Immune Regulation of Wound Re-epithelialization1K99AR072780-01LIU, SIQIROCKEFELLER UNIVERSITY, NY$96,930AMS
2018Targeting TGFB signaling to treat ocular neovascular disease1K99EY029375-01ZARKADA, GEORGIAYALE UNIVERSITY, CT$96,733ZEY1
2018Intrauterine Metal Exposure, Placental Gene Networks and Fetal Growth1K99ES029571-01DEYSSENROTH, MAYA ARIANEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$96,504ZES1
2018TMAO is a biomarker of dioxin-like pollutant exposure and cardiometabolic disease1K99ES028734-01A1PETRIELLO, MICHAEL CURTISUNIVERSITY OF KENTUCKY, KY$95,796ZES1
2018PCB induced neurogenic inflammation mediates bladder dysfunction1K99ES029537-01STIETZ, KIMBERLY PRESTON KEILUNIVERSITY OF CALIFORNIA AT DAVIS, CA$95,507ZES1
2018Volumetric optical connectome microscopy of human cerebellar circuitry1K99EB023993-01A1WANG, HUIMASSACHUSETTS GENERAL HOSPITAL, MA$94,986ZEB1
2018Characterizing genetic, longitudinal, and developmental effects on the transcriptome using a novel non-invasive RNA-sequencing method1K99HG009916-01CASTEL, STEPHANE EMILENEW YORK GENOME CENTER, NY$94,927GNOM
2018Mechanisms of visual encoding and plasticity in anterior cingulate cortex1K99EY028964-01SIDOROV, MICHAEL SUNIV OF NORTH CAROLINA CHAPEL HILL, NC$94,869ZEY1
2018HIV Prevention and Care1K99HD094648-01A1YOUNG, LINDSAY ERINUNIVERSITY OF CHICAGO, IL$94,832BSCH
2018The Extracellular Matrix in Muscle Atrophy1K99AR071508-01A1TALBERT, ERIN EMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$94,239AMS
2018Prenatal diet-stress interactions and the maternal metabolic response in human pregnancy1K99HD096109-01LINDSAY, KARENUNIVERSITY OF CALIFORNIA-IRVINE, CA$94,059CHHD
2018Development and Translation of D-glucose as an MRI Contrast Agent for Multiple Sclerosis1K99EB026312-01A1XU, XIANGHUGO W. MOSER RES INST KENNEDY KRIEGER, MD$93,960ZEB1
2018Mapping neurochemical activity of the basal ganglia in pathological behaviors1K99NS107639-01SCHWERDT, HELEN NMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$93,528NST
2018Mitochondrial retrograde signaling in RPE heterogeneity1K99EY029010-01A1DATTA, SAYANTANJOHNS HOPKINS UNIVERSITY, MD$93,125ZEY1
2018CELL-SPECIFIC MECHANISM AND FUNCTIONAL CONNECTIVITY IN TBI USING OPTOGENETIC fMRI1K99NS104243-01CRONE, JULIA SUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$92,934NST
2018Astrocyte regulation of neural plasticity after CNS injury1K99NS105915-01BURDA, JOSHUA EVANUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$92,930NST
2018Renal denervation to treat hypertension: Mechanisms and mediators1K99HL141650-01BANEK, CHRISTOPHER TUNIVERSITY OF MINNESOTA, MN$92,448MTI
2018Nature and contribution of noncoding, regulatory mutations in neurodevelopmental disorders1K99MH117165-01TURNER, TYCHELE NAOMIUNIVERSITY OF WASHINGTON, WA$92,108ZMH1
2018Dissecting the role of dorsomedial striatal circuitries in action selection during spatial exploration.1K99NS107721-01BOTTA, PAOLOCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$91,962NST
2018Voltage-gated sodium channel regulation of neocortical development1K99NS104215-01A1MAKINSON, CHRISTOPHER DONALDSTANFORD UNIVERSITY, CA$91,746NST
2018Characterizing novel neural crest derived regulators of hematopoietic stem cell specification1K99DK118253-01DAMM, ERICH WILLIAMST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$91,500DDK
2018Role of Nucleus Accumbens and Its Glutamatergic Inputs in High-Fat intake1K99DK115895-01A1CHRISTOFFEL, DANIEL JOSEPHSTANFORD UNIVERSITY, CA$91,500DDK
2018Information visualizations to facilitate clinician-patient communication in HIV care (Info Viz: HIV)1K99NR017829-01A1STONBRAKER, SAMANTHACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$91,363NRRC
2018Personalizing Sleep Interventions to Prevent Type 2 Diabetes in Community Dwelling Adults with Pre-Diabetes1K99NR017416-01MALONE, SUSAN KOHLNEW YORK UNIVERSITY, NY$91,351NRRC
2018Biomechanical Regulation of Angiogenesis during Tumor Progression1K99CA230202-01SEWELL-LOFTIN, MARY KATHRYNWASHINGTON UNIVERSITY, MO$91,044NCI
2018Epigenetic mechanisms of prenatal environmental stressors and offspring obesity risk1K99MD012808-01MARTIN, CHANTEL L.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$90,891ZMD1
2018Exploring the Microbiome-Gut-Brain Axis in Psychoneurological Symptoms for Children with Solid Tumors1K99NR017897-01BAI, JINBINGEMORY UNIVERSITY, GA$90,342NRRC
2018Sonomagnetic Imaging and Sonomechanical Control of Biological Processes in Deep Tissues1K99EB024600-01A1LU, GEORGE JCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$90,180ZEB1
2018Advancing Chronic Condition Symptom Cluster Science Through Use of Electronic Health Records and Data Science Techniques1K99NR017651-01KOLECK, THERESA ANNCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$90,050NRRC
2018Molecular mechanisms of sensory transduction in the gut1K99DK115879-01BELLONO, NICHOLASUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$90,000DDK
2018Elucidating How Primary Cilia Regulate Hedgehog Signaling by Super-Resolution Microscopy1K99GM126136-01SHI, XIAOYUUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$90,000ZGM1
2018Analyzing the role of chromatin compaction in nuclear mechanics, structure, and function1K99GM123195-01A1STEPHENS, ANDREW DANIELNORTHWESTERN UNIVERSITY, IL$90,000ZGM1
2018Principles of Chromatin Organization1K99GM127671-01ROWLEY, MICHAEL JORDANEMORY UNIVERSITY, GA$90,000ZGM1
2018Epigenetics in the extreme - investigating heritability driven by disordered RNA binding proteins in development and cancer1K99GM128180-01CHAKRAVARTY, ANUPAM KUMARSTANFORD UNIVERSITY, CA$90,000ZGM1
2018Mechanisms of Lis1 and NudE/L Regulation of the Molecular Motor Dynein1K99GM127757-01DESANTIS, MORGANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$90,000ZGM1
2018RNA tools for probing spliceosome dynamics1K99GM127752-01BRASELMANN, ESTHERUNIVERSITY OF COLORADO, CO$90,000ZGM1
2018Formation and function of lamellipodial morphology in 3D microenvironments1K99GM123221-01A1DRISCOLL, MEGHAN KATRIENUT SOUTHWESTERN MEDICAL CENTER, TX$90,000ZGM1

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