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NIH funding notice PA-18-398

NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed)

Closed on January 7, 2019.

Posted
November 29, 2017
Close date
January 7, 2019
Activity codes
K99, R00
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAMS, NIAID, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINR, NIMHD, NLM, NCCIH, NINDS, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-16-193 NIH Pathway to Independence Award (Parent K99/R00)
  2. 2 steps back: PA-16-077 NIH Pathway to Independence Award (Parent K99/R00)
  3. 3 steps back: PA-15-083 NIH Pathway to Independence Award (Parent K99/R00)
  4. 4 steps back: PA-14-042 NIH Pathway to Independence Award (Parent K99/R00)
  5. 5 steps back: PA-11-197 NIH Pathway to Independence Award (Parent K99/R00)
  6. 6 steps back: PA-10-063 NIH Pathway to Independence Award (Parent K99/R00)
  7. 7 steps back: PA-09-036 NIH Pathway to Independence Award (K99/R00)
  8. 8 steps back: PA-07-297 NIH Pathway to Independence (PI) Award (K99/R00)
  9. 9 steps back: PA-06-133

Replaced by PA-19-130.

Who won it before

1,388 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $154,511,716 in first-year total cost, median $103,918.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I]206
  2. NST-2 Study Section [NST-2]67
  3. NHLBI Mentored Transition to Independence Study Section[MTI (JA)]52
  4. Basic Neuroscience of Aging Study Section[NIA-N]50
  5. NHLBI Mentored Transition to Independence Study Section[MTI (MA)]45

Most frequent institutions

  1. STANFORD UNIVERSITY106
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO56
  3. MASSACHUSETTS GENERAL HOSPITAL44
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGO40
  5. JOHNS HOPKINS UNIVERSITY33
Competing awards under PA-18-398 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Orexin/hypocretin as a common mediator of stress and reward behavior in cocaine addiction1K99DA045765-01A1JAMES, MORGAN H.RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL, NJ$193,796ZDA1
2019Nucleus accumbens neuronal ensembles in drugs and natural rewards seeking.1K99DA046522-01A1BATCHELDER, ABIGAILMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$188,525ZDA1
2019Dissecting Stem Cell Intrinsic Signaling Driving Tumor Relapse from Immunotherapy1K99CA237859-01MIAO, YUXUAN PHOENIXROCKEFELLER UNIVERSITY, NY$183,708NCI
2019Integrative Genomic Analysis of Congenital Heart Disease1K99HL143036-01A1JIN, SHENG CHIHROCKEFELLER UNIVERSITY, NY$177,768MTI
2019Effects of exercise on dopaminergic mechanisms of cocaine relapse1K99DA047419-01A1ZLEBNIK, NATALIEUNIVERSITY OF MARYLAND BALTIMORE, MD$176,570ZDA1
2019Synergy of lipolysis and lipophagy in alcoholic liver disease1K99AA026877-01A1SCHOTT, MICAHMAYO CLINIC ROCHESTER, MN$173,556AA
2019Novel Mesolimbic Glutamate Projection in Reward1K99DA046514-01A1ZELL, VIVIEN EDOUARDUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$171,515ZDA1
2019Neural circuit control of mesolimbic dopamine and reward1K99DA047432-01COVEY, DANIEL PATRICKUNIVERSITY OF MARYLAND BALTIMORE, MD$169,842ZDA1
2019mechanisms of in situ functional stem cell heterogeneity in native and transplantation hematopoiesis1K99HL146983-01RODRIGUEZ FRATICELLI, ALEJO EZEQUIELBOSTON CHILDREN'S HOSPITAL, MA$168,005MTI
2019Processing of Apoptotic Cell-Derived Cargo by Macrophages Continues Efferocytosis and Drives Atherosclerosis Regression1K99HL145131-01YURDAGUL, ARIFCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$167,724MTI
2019Central regulation of sodium appetite via synergistic action of RAAS-sensitive neurons1K99HL144923-01RESCH, JONBETH ISRAEL DEACONESS MEDICAL CENTER, MA$166,104MTI
2019Characterization of the roles and regulation of Draxin in cranial neural crest1K99DE028592-01HUTCHINS, ERICACALIFORNIA INSTITUTE OF TECHNOLOGY, CA$164,160DSR
2019Elucidating behavior and neural circuits underlying opioid addiction and dependence1K99DA047413-01A1NGUYEN, JACQUES DUCHUYUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$161,358ZDA1
2019Identification and Characterization of Novel Genetic Mechanisms in Alcohol Use Disorder and Excessive Drinking1K99AA027835-01BARKLEY-LEVENSON, AMANDA MALINAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$160,311AA
2019Light-sheet micro-aspiration microscopy for the isolation and analysis of rare tumor cells from intact clinical specimens1K99CA240681-01GLASER, ADAM KUNIVERSITY OF WASHINGTON, WA$160,256NCI
2019Regulation of vascular metabolism in acute lung injury1K99HL145113-01WU, DAVID DUNIVERSITY OF CHICAGO, IL$160,056MTI
2019Deep machine learning to delineate trajectories of vulnerability and transition to mental illness in youth1K99MH118359-01A1DE LACY, NINAUNIVERSITY OF WASHINGTON, WA$157,009ZMH1
2019Macrophage Pyroptosis in Abdominal Aortic Aneurysm1K99HL145117-01A1WU, CONGQINGUNIVERSITY OF KENTUCKY, KY$156,481MTI
2019Improving Outcomes in Pediatric Obstructive Sleep Apnea with Computational Fluid Dynamics1K99HL144822-01A1BATES, ALISTERCINCINNATI CHILDRENS HOSP MED CTR, OH$153,171MTI
2019The role of endothelin-1 in tubular injury in sickle cell disease1K99HL144817-01A1KASZTAN, MALGORZATAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$152,777MTI
2019Sex Differences in Addiction1K99DA045758-01A1KOHTZ, AMYRBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL, NJ$150,668ZDA1
2019Relationship between Glaucoma and the Three-Dimensional Optic Nerve Head Related Structure1K99EY028631-01A1WANG, MENGYUSCHEPENS EYE RESEARCH INSTITUTE, MA$146,837ZEY1
2019Circuit Mechanisms for Conditioned Stress Regulation of Addiction1K99DA047426-01A1GARCIA KELLER, CONSTANZAMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$145,120ZDA1
2019Novel Mechanism of RBFox1 Mediated RNA Metabolism in Heart Failure1K99HL141626-01A1GAO, CHENUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$144,543MTI
2019Prometastatic Effects of Neoadjuvant Chemotherapy in Breast Cancer1K99CA237851-01KARAGIANNIS, GEORGE SALBERT EINSTEIN COLLEGE OF MEDICINE, NY$144,439NCI
2019Elucidating the mechanisms of intrinsic stem cell resistance to virus infection1K99AI141742-01WU, XIANFANGROCKEFELLER UNIVERSITY, NY$140,244AITC
2019Structure and Function of ATP-Dependent Chromatin Remodeling Complexes in Human Cancer1K99CA237855-01MASHTALIR, NAZARDANA-FARBER CANCER INST, MA$139,190NCI
2019High-throughput optical investigation into intact large-scale nervous systems for Alzheimers disease1K99AG059946-01 · under PA-16-193REN, JIANMASSACHUSETTS GENERAL HOSPITAL, MA$137,160NIA
2019Senescence-Associated Secretory Phenotype (SASP) modulation of the tumor microenvironment as a therapeutic strategy for KRAS-driven tumors1K99CA241110-01RUSCETTI, MARCUS A.SLOAN-KETTERING INST CAN RESEARCH, NY$137,117NCI
2019Role of Nucleus Accumbens D2-expressing Neurons in Punished Cocaine Seeking1K99DA044331-01A1 · under PA-16-193VENTO, PETER J.MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$137,040ZDA1
2019Molecular control of oocyte arrest, meiosis, and the transition to development1K99HD099315-01SWARTZ, STEVEN ZACHARYWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$136,755CHHD
2019Elucidating the mechanisms underlying sex differences in cognitive decline due to preclinical Alzheimer's disease1K99AG061238-01BUCKLEY, RACHEL FRANCESMASSACHUSETTS GENERAL HOSPITAL, MA$136,350NIA
2019The Vif-APOBEC Nexus1K99AI147811-01SALAMANGO, DANIEL JAMESUNIVERSITY OF MINNESOTA, MN$135,702AIDS
2019Assessing the Functional Consequences of Tau-Related Vasculature Changes using In Vivo Imaging1K99AG061259-01BENNETT, RACHEL ELISEMASSACHUSETTS GENERAL HOSPITAL, MA$135,591NIA
2019Discriminating between causes of age-related variegated gene expression1K99AG061216-01A1BURNAEVSKIY, NIKOLAYUNIVERSITY OF WASHINGTON, WA$134,325NIA
2019Genome-wide analysis of late-onset Alzheimer's disease using intergenerational, multi-trait, and cross-ancestry data1K99AG062787-01TURLEY, PATRICK ANSELMASSACHUSETTS GENERAL HOSPITAL, MA$134,282NIA
2019Transcriptional regulation of post-embryonic neuronal maturation1K99HD098371-01SUN, HAOSHENGCOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$132,543CHHD
2019Modernizing the Assessment of Financial Decision Making: Development and Evaluation of a Simulated Online Money Management Task in Older Adults1K99AG062783-01SUNDERARAMAN, PREETICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,543NIA
2019Mapping the germinal center and memory B cell landscape to complex antigens1K99AI145762-01ABBOTT, ROBERT KOEHLERLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$132,300AIDS
2019Genetic determinants of puberty and later life health outcomes1K99HD099330-01COUSMINER, DIANACHILDREN'S HOSP OF PHILADELPHIA, PA$131,733CHHD
2019Functional Alterations of Parvalbumin Interneurons Contributing to Abnormal Network Activity in Alzheimer's Disease Mouse Models1K99AG062776-01MA, KERANJ. DAVID GLADSTONE INSTITUTES, CA$131,328NIA
2019Design of vaccination strategies to elicit broadly neutralizing antibodies against HIV-11K99AI140770-01A1ESCOLANO, AMELIAROCKEFELLER UNIVERSITY, NY$130,972AIDS
2019Quantifying the Influence of Yogic Breathwork on Cerebrospinal Fluid Circulation1K99AT010158-01YILDIZ, SELDAOREGON HEALTH & SCIENCE UNIVERSITY, OR$130,950ZAT1
2019Integrative analysis of human placental epi/genome in relation to fetal growth1K99HD097286-01LESSEUR PEREZ, CORINAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$130,190CHHD
2019AAV-delivered broadly neutralizing antibodies for HIV suppression1K99AI138860-01A1GARDNER, MATTHEW RYANSCRIPPS FLORIDA, FL$129,870AIDS
2019Mechanisms of Aging: Regulation of Canonical and Non-canonical Autophagy1K99AG062774-01A1NIETO-TORRES, JOSE LUISSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$129,870NIA
2019ERPs reveal the Mechanisms of Bilingual Language Control1K99HD099325-01LI, CHUCHUUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$129,724CHHD
2019Proteomics Approach to Identify Cardiokine Signals in Human iPSC Models1K99HL144829-01LAU, EDWARDSTANFORD UNIVERSITY, CA$129,536MTI
2019Elucidating the role of SUMO ligase Su(var)2-10 in piRNA-guided transcriptional silencing and repressive chromatin formation1K99HD099316-01NINOVA, MARIA ANTONINOVACALIFORNIA INSTITUTE OF TECHNOLOGY, CA$129,465CHHD
2019Circadian Pattern of Rest-Activity Rhythms and Blood Pressure and the Underlying Epigenetic Mechanisms1K99HL148511-01MAKAREM, NOURCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$129,402MTI
2019The sex specific impact of anxiety on Alzheimer's disease progression1K99AG059953-01A1HUNSBERGER, HOLLY CHRISTIANNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$129,384NIA
2019Hippocampo-cortical circuit mechanisms of neuronal sequences during learning1K99MH120343-01FERNANDEZ-RUIZ, ANTONIONEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$129,087ZMH1
2019Mechanisms of Morphogen Transport and Interpretation in Early Embryos1K99HD097297-01LORD, NATHAN DALEHARVARD UNIVERSITY, MA$128,817CHHD
2019The Effects of Estrogen on Cardiac Arrhythmic Propensity1K99HL143211-01A1ITZHAKI, ILANITSTANFORD UNIVERSITY, CA$128,787MTI
2019Identifying the role of dynamic ECM-derived forces in zebrafish semicircular canal morphogenesis1K99HD098918-01MUNJAL, AKANKSHIHARVARD MEDICAL SCHOOL, MA$128,655ZHD1
2019Elucidation of cellular reprogramming processes that drive lens regeneration in axolotl as a basis for future therapeutic approaches1K99EY029361-01A1SOUSOUNIS, KONSTANTINOSHARVARD UNIVERSITY, MA$128,574ZEY1
2019Organizational and Cultural Dynamics in Genomics Companies: Industry Engagement in Navigating Social and Ethical Issues1K99HG010499-01WALKER, ALEXISJOHNS HOPKINS UNIVERSITY, MD$128,484ZRG1
2019Non-canonical FADD signaling as a genetic driver of invasive lobular carcinoma1K99CA237736-01TASDEMIR, NILGUNUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$128,012NCI
2019Investigating sex differences in persistent valvular myofibroblast activation using hydrogel culture substrates1K99HL148542-01AGUADO, BRIAN ALBERTOUNIVERSITY OF COLORADO, CO$127,827MTI
2019Quantitative characterization and predictive modeling of cranial bone development in patients with craniosynostosis1K99DE027993-01A1PORRAS PEREZ, ANTONIO REYESCHILDREN'S RESEARCH INSTITUTE, DC$127,765DSR
2019Pathways to scale up integrated early childhood development programs1K99HD097301-01BUCCINI, GABRIELAYALE UNIVERSITY, CT$127,576CHHD
2019Somatic regulation of embryonic germline dynamics by isoprenoids1K99HD097306-01BARTON, LACY JNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$127,246CHHD
2019Characterizing the assembly and age-related decline of neural circuits in Drosophila by single-cell profiling1K99AG062746-01LI, HONGJIESTANFORD UNIVERSITY, CA$127,035NIA
2019Neurobiological significance of Aqp4 stop codon readthrough1K99AG061231-01A1SAPKOTA, DARSHANWASHINGTON UNIVERSITY, MO$126,963NIA
2019Evolutionary insights into enterovirus tropism and pathogenesis1K99AI139279-01A1DOLAN, PATRICK TIMOTHYUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$126,630MID
2019Development of In Vitro Compression-Induced Rotator Cuff Injury Model: Aging and Inflammation in Tendon Degeneration1K99AG063896-01CONNIZZO, BRIANNE KATHRYNMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$125,863NIA
2019A SECRETED VIRAL PROTEIN DETERMINES NOROVIRUS PERSISTENCE BY IMMUNE EVASION1K99AI141683-01LEE, SANGHYUNWASHINGTON UNIVERSITY, MO$125,817MID
2019Identification of inputs to unipolar brush cells and their roles in multisensory processing1K99DC016905-01A1BALMER, TIMOTHY SOREGON HEALTH & SCIENCE UNIVERSITY, OR$125,550CDRC
2019Role of heparan sulfate in neural cell vulnerability to prions1K99AG061251-01A1AGUILAR CALVO, PATRICIAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$124,929NIA
2019Comprehensive Characterization of Adaptive Regulatory Variation Linked to Human Disease1K99HG010669-01REILLY, STEVEN K.BROAD INSTITUTE, INC., MA$124,916GNOM
2019Understanding the dynamics of cochlear amplification1K99DC016906-01A1CHARAZIAK, KAROLINAUNIVERSITY OF SOUTHERN CALIFORNIA, CA$124,374ZDC1
2019Senescent Vascular Cells as Mediators of Cognitive Decline1K99AG058798-01A1SCHAFER, MARISSA JOYMAYO CLINIC ROCHESTER, MN$124,362NIA
2019Identification and Characterization of Common Pathways across Alzheimer Disease Genotypes using a Multiomic Approach1K99AG061281-01A1FERNANDEZ HERNANDEZ, MARIA-VICTORIAWASHINGTON UNIVERSITY, MO$124,239NIA
2019Multimodal Investigation of the Neuroimmune System in Opioid Use Disorder1K99DA048125-01WOODCOCK, ERIC ANDREWYALE UNIVERSITY, CT$123,325ZDA1
2019The impact of dietary zinc deficiency on innate immunity to lung infection1K99HL143441-01A1PALMER, LAUREN DISTERHOFTVANDERBILT UNIVERSITY MEDICAL CENTER, TN$122,710MTI
2019A Systems Approach to Understanding the Interacting Factors of the Local Food Environment for Population Health1K99HL144824-01A1WINKLER, MEGANUNIVERSITY OF MINNESOTA, MN$122,417MTI
2019Structural Basis of Quantal Release1K99MH119591-01LI, FEIUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,230ZMH1
2019Mechanistic studies of the menthol receptor TRPM8: a novel target for analgesic drugs1K99AT010478-01DIVER, MELINDAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,230ZAT1
2019Neural encoding of associative learning by orbitofrontal cortex circuits1K99MH118422-01A1K NAMBOODIRI, VIJAY MOHANUNIVERSITY OF WASHINGTON, WA$121,051ZMH1
2019Behavioral and physiological linkage in people with frontotemporal dementia and spousal caregivers1K99AG059947-01A1CHEN, KUAN-HUAUNIVERSITY OF CALIFORNIA BERKELEY, CA$120,960NIA
2019Social Disadvantage and Its Impact on Pathogen Burden and Immune Dysfunction Across the Life Course1K99AG062749-01A1NOPPERT, GRACE AUNIV OF NORTH CAROLINA CHAPEL HILL, NC$120,250NIA
2019Metabolic Rewiring of the Heart Through Reductive Carboxylation1K99HL141702-01A1KARLSTAEDT, ANJAUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$120,193MTI
2019Cortical representations of harmonic and virtual pitch in humans1K99DC017472-01A1MEHTA, ANAHITA HUNIVERSITY OF MINNESOTA, MN$120,156CDRC
2019Leveraging Functional Selectivity in the Neurotensin Receptor 1-Mediated Treatment of Addiction1K99DA048970-01SLOSKY, LAUREN MDUKE UNIVERSITY, NC$119,463ZDA1
2019The development and application of tools to characterize the level and function of RNA polymerase III transcription dynamics during cellular differentiation1K99HG010362-01A1VAN BORTLE, KEVINSTANFORD UNIVERSITY, CA$118,931GNOM
2019Combinatorial approach to develop novel pre-therapeutic agents targeting virulence factors essential to clinically relevant pathogens1K99AI139281-01A1LAM, HANH NGOCUNIVERSITY OF CALIFORNIA SANTA CRUZ, CA$118,224MID
2019Integrating imaging and computation to characterize neural crest cells in the myocardial development and regeneration1K99HL148493-01DING, YICHENUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$117,475MTI
2019A-to-I RNA modifications in mouse oocytes1K99HD099269-01BRACHOVA, PAVLAUNIVERSITY OF KANSAS MEDICAL CENTER, KS$117,396ZHD1
2019Role of Arginase 1 in Retinal Ischemia-Reperfusion Injury1K99EY029373-01A1FOUDA, ABDELRAHMANAUGUSTA UNIVERSITY, GA$116,694ZEY1
2019Neural circuitry of distress tolerance1K99DA045764-01A1MOSCHAK, TRAVIS MUNIV OF NORTH CAROLINA CHAPEL HILL, NC$116,223ZDA1
2019TOOLS FOR NORMALIZING AND INTERPRETING THE CLINICAL ACTIONABILITY OF GENOMIC VARIANTS1K99HG010157-01A1WAGNER, ALEX HANDLERWASHINGTON UNIVERSITY, MO$115,001GNOM
2019Interacting neural mechanisms of selective visual attention and value-based decision-making1K99EY029759-01A1CHEN, XIAOMOSTANFORD UNIVERSITY, CA$114,391ZEY1
2019A molecular informed therapy for Diffuse Intrinsic Pontine Gliomas (DIPG)1K99CA234434-01PIUNTI, ANDREANORTHWESTERN UNIVERSITY AT CHICAGO, IL$114,370NCI
2019Ribosomes and Regeneration: Defining the Role of Protein Synthesis in Tissue Development, Homeostasis and Repair.1K99HD099787-01ZHULYN, OLENASTANFORD UNIVERSITY, CA$111,916CHHD
2019SAFEGENOMES: Strong privacy Assurance For Effective GENOME Sharing1K99HG010493-01BONOMI, LUCAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$111,266GNOM
2019Modeling a neural circuit for flexible control of innate behaviors1K99MH117264-01A1KENNEDY, ANN KATHRYNCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$110,754ZMH1
2019Synergistic effect of maternal insulin-resistance and cortisol in pregnancy on fetal programming of child mitochondrial function and obesity risk1K99HD097302-01GYLLENHAMMER, LAUREN ELIZABETHUNIVERSITY OF CALIFORNIA-IRVINE, CA$110,714CHHD
2019Therapeutic Rescue of a Deficient BMPR2 Hypoxic Response in Pulmonary Arterial Hypertension1K99HL145097-01A1MARCIANO, DAVID PSTANFORD UNIVERSITY, CA$110,291MTI
2019A novel role for endothelial mineralocorticoid receptors in obesity-associated cardiovascular disease in females1K99HL146948-01FAULKNER, JESSICA L.AUGUSTA UNIVERSITY, GA$110,160MTI
2019Nonpersistent chemical exposure, placental development, and maternal pre- and post-pregnancy cardiovascular health1K99ES030403-01KAHN, LINDA GNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$110,052ZES1
2019Environmental Mitochondrial Toxicants Cause LRRK2 Activation in Parkinson's disease1K99ES029986-01DE MIRANDA, BRIANAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$109,858ZES1
2019Editing the Neural Basis of Perception1K99EY029758-01OLDENBURG, IAN ANTONUNIVERSITY OF CALIFORNIA BERKELEY, CA$109,836ZEY1
2019Longitudinal investigation of the relation between attention, neural functioning and SES in infancy.1K99HD099328-01BURRIS , JESSICA LRUTGERS THE STATE UNIV OF NJ NEWARK, NJ$109,516CHHD
2019Defining the Role of Microglia in the Synaptic Rewiring of the Hypothalamus by Early life Adversity1K99MH120327-01BOLTON, JESSICA LYNNUNIVERSITY OF CALIFORNIA-IRVINE, CA$109,031ZMH1
2019Defining and targeting the metabolic landscape in Acute Myeloid Leukemia1K99CA241370-01DI MARCANTONIO, DANIELARESEARCH INST OF FOX CHASE CAN CTR, PA$108,686NCI
2019Substrates and functions of the Sideroflexin mitochondrial transporter family1K99CA241332-01KORY, NORAWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$107,999NCI
2019Whole heart suspended animation: leveraging the zebrafish to solve the organ shortage1K99HL143149-01A1TESSIER, SHANNON NOELLAMASSACHUSETTS GENERAL HOSPITAL, MA$107,568MTI
2019Defining the role of respiratory gland patterning in rhinosinusitis1K99HL145094-01A1MAY, ALISONUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$105,624MTI
2019Large-scale CRISPR screening of essential calcium-related genes in the human parasite Trypanosoma cruzi1K99AI137322-01A1LANDER, NOELIAUNIVERSITY OF GEORGIA, GA$104,708MID
2019Homeostatic Plasticity of the Respiratory Rhythm Generating Network1K99HL145004-01BAERTSCH, NATHAN ANDREWSEATTLE CHILDREN'S HOSPITAL, WA$104,687MTI
2019A new system for modeling supernumerary chromosome dynamics and formation during meiosis.1K99HD099276-01HANLON, STACEY LSTOWERS INSTITUTE FOR MEDICAL RESEARCH, MO$104,205CHHD
2019The Role of CHAF1B in Maintaining Malignant Leukemia Stem Cells1K99CA230314-01A1VOLK, ANDREWNORTHWESTERN UNIVERSITY AT CHICAGO, IL$104,101NCI
2019p62 in Cancer: Mechanism and Regulation1K99CA241301-01ZHANG, YIUNIVERSITY OF COLORADO DENVER, CO$103,328NCI
2019Determining the Immunological Consequences of DNA Replication Stress Response Defects in Renal Cells Carcinoma to Improve Immunotherapy Outcomes1K99CA240689-01MCGRAIL, DANIEL JAMESUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$103,303NCI
2019Roles of higher-order visual thalamus in state-dependent corticocortical communication1K99EY030550-01NESKE, GARRETTYALE UNIVERSITY, CT$103,230ZEY1
2019Inhibitory control of visual cortical circuits1K99EY030549-01FERGUSON, KATHERINEYALE UNIVERSITY, CT$103,230ZEY1
2019MicroRNAs, ER stress and arsenic neurotoxicity1K99ES029548-01A1PARK, HAE-RYUNGHARVARD SCHOOL OF PUBLIC HEALTH, MA$102,794ZES1
2019Role of Wnt-responsive cells in oral mucosa homeostasis, injury, and malignancy1K99DE028585-01YUAN, XUESTANFORD UNIVERSITY, CA$102,758DSR
2019Developing Remyelination Strategies for Demyelinating Optic Neuropathies Using Human Pluripotent Stem Cells1K99EY029011-01A1CHAMLING, XITIZJOHNS HOPKINS UNIVERSITY, MD$102,451ZEY1
2019The role of autism susceptibility genes in the 16p11.2 locus on the development and function of human stem cell-derived neural cells1K99MH119327-01WELLS, MICHAEL FREDERICKBROAD INSTITUTE, INC., MA$102,330ZMH1
2019Characterizing the pathogenesis and targeted therapeutics of Wilms' Tumor 1 (WT1) mutations in AML1K99CA237630-01ZHANG, HAIJIAOOREGON HEALTH & SCIENCE UNIVERSITY, OR$102,142NCI
2019Functional dissection of the regulatory network that governs cardiomyocyte maturation.1K99HL143194-01A1VANDUSEN, NATHAN JAMESBOSTON CHILDREN'S HOSPITAL, MA$101,992MTI
2019Exploring novel regulatory mechanisms underlying enhancer activation and cell fate transition1K99HD094906-01A1CAO, KAIXIANGNORTHWESTERN UNIVERSITY AT CHICAGO, IL$101,557CHHD
2019Identifying long-range polarity cues using spontaneous mutations in mammals1K99HD097298-01CETERA, MAUREEN PATRICIAPRINCETON UNIVERSITY, NJ$101,502CHHD
2019Impact of ketone bodies on age-related inflammation and healthspan extension1K99AG058801-01A1GOLDBERG, EMILY LAURENYALE UNIVERSITY, CT$101,499NIA
2019Targeting ZDHHC13-activated palmitoylation for melanoma treatment1K99CA234097-01A1CHEN, SHUYANGBOSTON UNIVERSITY MEDICAL CAMPUS, MA$101,368NCI
2019Prenatal Metal Mixtures, Fetal Growth, and the Role of MicroRNAs1K99ES030400-01HOWE, CAITLIN GRACEUNIVERSITY OF SOUTHERN CALIFORNIA, CA$100,980ZES1
2019Deamidation-mediated metabolic reprogramming by KSHV in cell proliferation and tumorigenesis1K99DE028973-01ZHAO, JUNUNIVERSITY OF SOUTHERN CALIFORNIA, CA$100,958DSR
2019Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade1K99HD097290-01EDWARDS, LAURAEMORY UNIVERSITY, GA$100,901CHHD
2019The Regulation of Lymphatic Muscle Cell Pacemaking by Intracellular Calcium Signals1K99HL143198-01A1ZAWIEJA, SCOTT D.UNIVERSITY OF MISSOURI-COLUMBIA, MO$100,377MTI
2019Defining the regulatory roles of alternative ribosome initiation and novel peptides1K99GM134154-01CHEN, JINUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$100,000ZGM1
2019Mechanisms and functions of repressive chromatin structure in quiescent cells.1K99GM134150-01SWYGERT, SARAH GRACEFRED HUTCHINSON CANCER RESEARCH CENTER, WA$100,000ZGM1
2019Three-dimensional super-resolution imaging and tracking of disease and treatment mechanisms of progeria1K99GM134187-01GUSTAVSSON, ANNA KARIN EVASTANFORD UNIVERSITY, CA$100,000ZGM1
2019Molecular Mechanisms of PTEN and USP7 Regulation1K99GM130961-01A1DEMPSEY, DANIEL R.BRIGHAM AND WOMEN'S HOSPITAL, MA$100,000ZGM1
2019Structural understanding of human shelterin complex assembly at telomere and its regulation mechanism of telomerase activity1K99GM131023-01LIM, CI JIUNIVERSITY OF COLORADO, CO$99,999ZGM1
2019Mapping the assembly pathways for viral capsids by direct single-particle measurements1K99GM127751-01A1GARMANN, REES FHARVARD UNIVERSITY, MA$99,999ZGM1
2019Molecular mechanisms that regulate target cell sensitivity to Hedgehog morphogens1K99GM132518-01KONG, JENNIFERSTANFORD UNIVERSITY, CA$99,999ZGM1
2019Evolutionary and functional consequences of structural genetic variation in Drosophila1K99GM129411-01A1CHAKRABORTY, MAHULUNIVERSITY OF CALIFORNIA-IRVINE, CA$99,999ZGM1
2019Control of topoisomerase activity during DNA replication by bacterial chromosome structuring proteins1K99GM134153-01GUO, MONICA S.MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$99,999ZGM1
2019Mechanisms for histone segregation at DNA replication forks and implications for epigenetic inheritance.1K99GM134180-01SERRA CARDONA, ALBERTCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$99,999ZGM1
2019Deciphering the logic of glycolipid signaling at the host-microbiome interface1K99GM130964-01A1JOST, MARCOUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$99,999ZGM1
2019HIGH-THROUGHPUT FUNCTIONAL INTERROGATION OF MAMMALIAN ACTIVATION DOMAINS1K99GM131022-01STALLER, MAX VALENTINWASHINGTON UNIVERSITY, MO$99,998ZGM1
2019Defining the function of extracellular ATP sensing for memory CD8+ T cell generation and longevity1K99AI139381-01A1BORGES DA SILVA, HENRIQUEUNIVERSITY OF MINNESOTA, MN$99,705AITC
2019Heme allocation and disruptions in asthma and the failing heart1K99HL144921-01A1SWEENY, ELIZABETH A.CLEVELAND CLINIC LERNER COM-CWRU, OH$99,661MTI
2019Uncovering roles of metabolites in colorectal cancer etiology1K99CA230205-01A1SHU, XIANGVANDERBILT UNIVERSITY MEDICAL CENTER, TN$99,482NCI
2019Mechanisms of Environmental-Mixture Induced Metabolic Disruption1K99ES030405-01KASSOTIS, CHRISTOPHER DENNISDUKE UNIVERSITY, NC$99,477ZES1
2019Mechanistic understanding of influenza-host interactions from a zoonotic perspective1K99AI139445-01A1WU, NICHOLAS C.SCRIPPS RESEARCH INSTITUTE, THE, CA$99,350MID
2019Neural Circuit Mechanisms for Visual Features Representation in the Superior Colliculus of Behaving Mice1K99EY028640-01A1LI, YATANGCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$99,009ZEY1
2019Identification of immunotherapeutic targets in cardiovascular disease1K99HL146951-01BERSI, MATTHEW RYANVANDERBILT UNIVERSITY, TN$98,981MTI
2019Myonuclear Epigenetics of Skeletal Muscle Mass Regulation with Age1K99AG063994-01MURACH, KEVINUNIVERSITY OF KENTUCKY, KY$98,734NIA
2019Epigenetic and developmental regulation of embryonic plasticity and gametogenesis1K99HD096053-01A1GLEASON, RYAN JOSEPHJOHNS HOPKINS UNIVERSITY, MD$98,261CHHD
2019Exercise, MANF, and chemical-induced neurodegeneration1K99ES029552-01A1HARTMAN, JESSICA HELENEDUKE UNIVERSITY, NC$98,129ZES1
2019Myofilament proteins in cardiomyopathy and arrhythmias1K99HL141698-01A1BAREFIELD, DAVID YNORTHWESTERN UNIVERSITY AT CHICAGO, IL$97,783MTI
2019Defining new pathways for cardiac automaticity1K99HL146969-01EL REFAEY, MONAOHIO STATE UNIVERSITY, OH$97,063MTI
2019Investigating the role of cell competition in epidermal development1K99AR074557-01ELLIS, STEPHANIEROCKEFELLER UNIVERSITY, NY$97,029AMS
2019Molecular and biophysical mechanism of plasma membrane internalization during nonclathrin endocytosis1K99GM132551-01AKAMATSU, MATTHEW SATAROUNIVERSITY OF CALIFORNIA BERKELEY, CA$96,768ZGM1
2019Uncovering the Role of Synaptonemal Complex in Meiotic Recombination by Cryo-electron Tomography1K99GM132544-01KASINATH, VIGNESHUNIVERSITY OF CALIFORNIA BERKELEY, CA$96,768ZGM1
2019Endothelial dependent mechanisms of lymphatic dysfunction in metabolic syndrome and type-2 diabetes associated with obesity1K99HL141143-01A1CASTORENA, JORGE AUGUSTOUNIVERSITY OF MISSOURI-COLUMBIA, MO$96,071MTI
2019Molecular mechanisms of centriolar triplet microtubule formation1K99GM131024-01WANG, JENNIFER TONGSTANFORD UNIVERSITY, CA$94,970ZGM1
2019Elucidating the mechanism for malaria rhythmicity: an underlying circadian clock of the parasite1K99GM132557-01RIJO-FERREIRA, FILIPAUT SOUTHWESTERN MEDICAL CENTER, TX$94,726ZGM1
2019Trans-synaptic mechanism of retinal synapse formation and function1K99EY030554-01WANG, YUCHENSCRIPPS FLORIDA, FL$94,443ZEY1
2019Deciphering mechanisms of nitrogen-containing bisphosphonates1K99AR073903-01A1SURFACE, LAUREN ELIZABETHMASSACHUSETTS GENERAL HOSPITAL, MA$94,100AMS
2019Determining the importance of temporal regulation of the blood-brain barrier1K99HL147212-01ZHANG, SHIRLEYUNIVERSITY OF PENNSYLVANIA, PA$94,093MTI
2019Unraveling stem cell behaviors upon injury to the brain1K99NS112605-01BAYIN, NERMIN SUMRUSLOAN-KETTERING INST CAN RESEARCH, NY$94,068NST
2019Molecular mechanisms regulating chromatin looping in time and space1K99GM130896-01HANSEN, ANDERS SEJRUNIVERSITY OF CALIFORNIA BERKELEY, CA$93,528ZGM1
2019Magnetic Modulation on Targeted Neural Circuits in Autism1K99MH120279-01RAO, SIYUANMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$93,506ZMH1
2019Real-time Non-Rigid 3D Reconstruction and Registration for Laparoscopic-guided Minimally Invasive Liver Surgery1K99EB027177-01A1ZHOU, HAOYINBRIGHAM AND WOMEN'S HOSPITAL, MA$93,280ZEB1
2019Interrogation of Microbial Natural Product Methyltransferases1K99GM129454-01A1DAVIS, TONY D.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$93,040ZGM1
2019Is Preeclampsia and Spontaneous Preterm Delivery Associated with Vascular and Cardiac Function?1K99NR018679-01MINISSIAN, MARGOCEDARS-SINAI MEDICAL CENTER, CA$92,928NRRC
2019Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation1K99DA046564-01 · under PA-16-193HEBERT, EMILY TAYLORUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$92,213ZDA1
2019Optimized MR Fingerprinting for Rapid Volumetric Quantitative Neuroimaging1K99EB027181-01ZHAO, BOMASSACHUSETTS GENERAL HOSPITAL, MA$92,118ZEB1
2019Role for ion conducting proteins in cortical malformation diseases1K99NS112604-01SMITH, RICHARD SBOSTON CHILDREN'S HOSPITAL, MA$92,102NST
2019Integrative data science approaches for rare disease discovery in health records1K99LM012992-01PEJAVER, VIKAS RAOUNIVERSITY OF WASHINGTON, WA$92,070ZLM1
2019Mechanistic investigation of in vivo pathways of neuronal mitochondrial degradation1K99NS111000-01INSOLERA, RYANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$91,800NST
2019Systematic multidisciplinary approach to study traumatic bleeding as a complex structural and biomechanical problem1K99HL148646-01TUTWILER, VALERIEUNIVERSITY OF PENNSYLVANIA, PA$91,746MTI
2019Stress effects on circuitry regulating nigrostriatal dopamine during goal-directed action1K99MH119312-01HOLLON, NICK GARBERSALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$91,505ZMH1
2019Sex Differences in Renal Sodium Handling1K99DK119413-01GOHAR, EMANUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$91,500DDK
2019Microbiota-dependent Epigenetic Regulation of Circadian Rhythms in Nutrient Uptake and Energy Homeostasis1K99DK120897-01KUANG, ZHENGUT SOUTHWESTERN MEDICAL CENTER, TX$91,500DDK
2019Sympathetic Control of Liver Metabolism1K99DK120894-01CARON, ALEXANDREUT SOUTHWESTERN MEDICAL CENTER, TX$91,500DDK
2019R-loop in Transcription and DNA Replication1K99DK120952-01CHEN, JIAYUUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$91,500DDK
2019Immune Checkpoints for Intestinal Innate Lymphoid Cells1K99DK118110-01A1BANDO, JENNIFER KAORUWASHINGTON UNIVERSITY, MO$91,500DDK
2019Disentangling discrete lateral hypothalamic circuits involved in feeding and obesity1K99DK121883-01ROSSI, MARK ALLENUNIVERSITY OF WASHINGTON, WA$91,500DDK
2019Extracellular Vesicle‐mediated Regulation of Metabolism1K99DK122019-01CREWE, CLAIRUT SOUTHWESTERN MEDICAL CENTER, TX$91,500DDK
2019Sphingolipid and Fatty Acid Biology in Prediabetes and Neuropathy1K99DK119366-01A1RUMORA, AMY E.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$91,500DDK
2019Chronic Inflammation and Type 2 Diabetes: A Multi-omics Approach1K99DK122128-01LI, JUNHARVARD SCHOOL OF PUBLIC HEALTH, MA$91,499DDK
2019Primate-specific miRNAs in Embryonic and Placental Development1K99HD099154-01SCHMIDT, JENNA ANNUNIVERSITY OF WISCONSIN-MADISON, WI$91,031CHHD
2019Dissecting the action learning process with dopaminergic reinforcement1K99NS112575-01TANG, JONATHANCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$90,828NST
2019Studies of histone serotonylation and its role in transcriptional and neural plasticity1K99MH120334-01FARRELLY, LORNAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$90,450ZMH1
2019Synthetic DNA-free circuits for “scarless” programming of mammalian cells1K99EB027723-01GAO, XIAOJING JCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$90,180ZEB1
2019Epigenetic Regulation of Chondrogenesis and Cartilage Development1K99AR075899-01WU, CHIA-LUNGWASHINGTON UNIVERSITY, MO$90,098AMS
2019Regulation of mRNA transcription by the Integrator complex1K99GM131028-01TATOMER, DEIRDREUNIVERSITY OF PENNSYLVANIA, PA$90,000ZGM1
2019Functionality of CdrA and its processed forms within Pseudomonas aeruginosa biofilms1K99GM134121-01REICHHARDT, COURTNEYUNIVERSITY OF WASHINGTON, WA$90,000ZGM1
2019Characterization of novel subtypes in B progenitor acute lymphoblastic leukemia1K99CA241297-01GU, ZHAOHUIST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$89,999NCI
2019High-Precision Non-Contact Plasmon-Induced Intracellular Delivery1K99EB028325-01CHIANG, NAIHAOUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$89,754ZEB1
2019Novel Informatics Techniques for Modeling and Analyzing Brain Structure for Facilitating Diagnosis of Neurological Diseases1K99LM012874-01A1ZHANG, MINBRIGHAM AND WOMEN'S HOSPITAL, MA$89,675ZLM1
2019Characterization of MeCP2-dependent gene regulation with temporal and mechanistic precision1K99NS112415-01BOXER, LISA D.HARVARD MEDICAL SCHOOL, MA$89,370NST
2019Multi-objective representation learning methods for interpetable predictions of patient outcomesusing electronic health records1K99LM012926-01A1LA CAVA, WILLIAMUNIVERSITY OF PENNSYLVANIA, PA$89,260ZLM1
2019The metabolomic consequences of small size and long life1K99AG059920-01A1HOFFMAN, JESSICA MARIEUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$89,167NIA
2019Neural and computational mechanisms underlying the assembly of motor skills1K99NS112597-01MARSHALL, JESSE D.HARVARD UNIVERSITY, MA$88,506NST
2019Investigating the role of TCF4 in human interneuron function and dysfunction1K99MH119319-01BIREY, FIKRISTANFORD UNIVERSITY, CA$88,424ZMH1

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