The notices it replaced
- Reissues: PA-19-056 Research Project Grant (Parent R01 Clinical Trial Not Allowed)
- 2 steps back: PA-18-484 NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
- 3 steps back: PA-16-160 NIH Research Project Grant (Parent R01)
- 4 steps back: PA-13-302 Research Project Grant (Parent R01)
- 5 steps back: PA-11-260 Research Project Grant (Parent R01)
- 6 steps back: PA-10-067 Research Project Grant (Parent R01)
- 7 steps back: PA-07-070 Research Project Grant (Parent R01)
Replaced by PA-25-301.
Who won it before
54,180 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $29,239,116,505 in first-year total cost, median $470,496.
Most frequent study sections
- Surgery, Anesthesiology and Trauma Study Section[SAT]479
- Auditory System Study Section[AUD]432
- Genetics of Health and Disease Study Section[GHD]422
- Hepatobiliary Pathophysiology Study Section[HBPP]398
- Pathobiology of Kidney Disease Study Section[PBKD]393
Most frequent institutions
- UNIVERSITY OF MICHIGAN AT ANN ARBOR1,263
- UNIVERSITY OF PENNSYLVANIA1,207
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH1,205
- JOHNS HOPKINS UNIVERSITY1,189
- WASHINGTON UNIVERSITY1,092
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | The oral environment in food allergy development (ONEIDA)1U01AI192609-01 | BUNYAVANICH, SUPINDA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $6,732,986 | CRD |
| 2025 | Moderation of Aging Trajectories of Cognition and Neuropathology by Diet Composition in Middle-aged Nonhuman Primates1RF1AG092490-01 | BAXTER, MARK GSHIVELY, CAROL A.SOLINGAPURAM SAI, KIRAN | WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC | $6,424,607 | ASG |
| 2025 | Accumulation of micro- and nanoplastic particles in mammalian tissues: a translational study1R01ES036575-01A1 | FLORSHEIM, REBECCASTAPLETON, PHOEBE | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $5,453,538 | EDD |
| 2025 | Skin microbes and development of allergic disease1R01AI192662-01 | GALLO, RICHARD LKNIGHT, ROBNAKATSUJI, TERUAKI | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $5,176,858 | ZRG1 |
| 2025 | Microbial Programming of T-cell Migration from Gut to Brain1R01AI193160-01 | HAFLER, DAVID A.PALM, NOAH WOLCOTTWANG, ANDREW | YALE UNIVERSITY, CT | $4,908,988 | CNBT |
| 2025 | Leveraging novel pediatric SHIVs to identify biomarkers of prophylactic efficacy of bnAb against breast milk HIV transmission1R01AI184074-01A1 | FOUDA AMOU OU, GENEVIEVE GINY | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $4,686,370 | ZRG1 |
| 2025 | Germline variation in homologous recombination repair genes in Hispanic/Latina women to predict breast cancer risk and response to treatment1R01MD021367-01 | NEUHAUSEN, SUSAN L.ZIV, ELAD | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $4,307,388 | ZRG1 |
| 2025 | Leveraging Omics and Electronic Health Records Data to study Colorectal Adenoma genetics and Drug Repurposing1R01CA297582-01A1 | GUO, XINGYIYIN, ZHIJUN | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $4,174,595 | CHD |
| 2025 | Role of NYC's Universal Pre-K Expansion on the Health and Education of Children1R01NR022285-01A1 | ELBEL, BRIAN | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $4,109,158 | CIHB |
| 2025 | Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers1R01AG095513-01 | LI, CLARAPAREKH, ANKIT ASHOKSPAT-LEMUS, JESSICAZHANG, BIN | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $4,035,962 | AIMR |
| 2025 | Proteasome Targeting for Alloreactive Plasma Cells2R01AI154932-06 | ALLMAN, DAVID MHILDEMAN, DAVID A | UNIVERSITY OF PENNSYLVANIA, PA | $3,810,794 | ITA |
| 2025 | LitCog V: Health Literacy and Cognitive Function Among Older Adults2RF1AG030611-18 | WOLF, MICHAEL S | NORTHWESTERN UNIVERSITY, IL | $3,782,845 | CMGC |
| 2025 | Dissecting CCL5 contribution to antigen specific T cell responses in head and neck cancers1R01DE034386-01A1 | RODIG, SCOTT JUPPALURI, RAVINDRA | DANA-FARBER CANCER INST, MA | $3,742,682 | TIO |
| 2025 | Optimizing validity of comparative effectiveness research in Alzheimer's disease and related dementias using large language models1RF1AG090405-01A1 | LIN, JOSHUA KYANG, JIE | BRIGHAM AND WOMEN'S HOSPITAL, MA | $3,687,278 | ZRG1 |
| 2025 | Project Prakash: Development of Object Perception After Late Sight Onset2R01EY020517-12A1 | SINHA, PAWAN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $3,685,443 | HCMF |
| 2025 | tRNA fragments and their role in tau pathology in Alzheimer's disease and tauopathies1RF1AG090598-01A1 | KRICHEVSKY, ANNA M. | BRIGHAM AND WOMEN'S HOSPITAL, MA | $3,672,952 | MNG |
| 2025 | FunGen-xQTL: Unraveling the genetic basis of molecular functions in Alzheimer's Disease1R01AG086467-01A1 | TCW, JULIAWANG, GAOZHANG, XIAOLING | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $3,642,232 | ZRG1 |
| 2025 | Hyaluronidase mediated GBS Disease1R01AI192624-01 | RAJAGOPAL, LAKSHMI | SEATTLE CHILDREN'S HOSPITAL, WA | $3,613,118 | BHI |
| 2025 | Assessing the effects of oral pre-exposure prophylaxis on pharmacokinetics of monoclonal and vaccine-induced antibodies among women vulnerable to HIV-11R01AI192148-01A1 | HUANG, YUNDALEMOS, MARIA P | FRED HUTCHINSON CANCER CENTER, WA | $3,554,273 | HIVD |
| 2025 | Assessing the Role of Sex-Specific Genetic Drivers of Cerebrovascular Disease in the Alzheimer's Disease Brain1RF1AG090932-01A1 | DUMITRESCU, LOGAN C | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $3,531,593 | NMBH |
| 2025 | Chromatin architecture regulating trained immunity in antiviral NK cells1R01AI189793-01A1 | SUN, JOSEPH CHAI-YUEN | SLOAN-KETTERING INST CAN RESEARCH, NY | $3,519,992 | ZRG1 |
| 2025 | AI Methods for Large Scale Epidemiological Studies using Patient Reports of Medication Adherence and Tolerability1R01LM014731-01A1 | GONZALEZ HERNANDEZ, GRACIELASHEN, LI | CEDARS-SINAI MEDICAL CENTER, CA | $3,484,662 | ZRG1 |
| 2025 | Identifying Relapse Predictors and Therapeutic Vulnerabilities in Ph+ and Ph-like Acute Lymphoblastic Leukemia1R01CA293587-01A1 | LOH, MIGNON LEE-CHEUNTASIAN, SARAH KATHLEENYANG, JUN J. | SEATTLE CHILDREN'S HOSPITAL, WA | $3,480,276 | MCTC |
| 2025 | Molecular Mechanisms and Genetic Basis of Human Ovarian Aging1RF1AG093116-01 | ROSENFELD, MICHAEL GSUH, YOUSINWILLIAMS, ZEV | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $3,445,585 | GHD |
| 2025 | TLE transcription cofactors in anti-viral and anti-tumor immunity1R01AI187349-01A1 | XUE, HAI-HUI | HACKENSACK UNIVERSITY MEDICAL CENTER, NJ | $3,436,588 | AI |
| 2025 | Epigenetic Checkpoint Regulation of Naive T-cell Quiescence and Peripheral Tolerance1R01AI187465-01A1 | CHENG, YONGFENG, YONGQIANG | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $3,428,212 | AI |
| 2025 | The Impact of the Bone Marrow Niche's Immune Privilege on Psoriatic Arthritis1R01AI194935-01 | ADAMOPOULOS, IANNIS ELIASFUJISAKI, JOJI | BETH ISRAEL DEACONESS MEDICAL CENTER, MA | $3,406,145 | ZRG1 |
| 2025 | The Impact of the 11th Street Bridge Park on the Built Environment and Community Health: Washington, D.C.1R01NR021883-01 | DIPIETRO, LORETTA | GEORGE WASHINGTON UNIVERSITY, DC | $3,399,035 | HPC |
| 2025 | Design and testing of immunogens to elicit 10E8-like broadly neutralizing antibodies against HIV2R01AI147826-06A1 | SCHIFFNER, TORBEN | SCRIPPS RESEARCH INSTITUTE, THE, CA | $3,383,634 | HIVD |
| 2025 | Advancing women’s care in Alzheimer’s disease and other dementias through EHR1RF1AG090341-01A1 | SOHN, SUNGHWAN | MAYO CLINIC ROCHESTER, MN | $3,377,863 | ZRG1 |
| 2025 | Defining the impact of type 1 cytokine signaling on STAT-mediated epithelial reprogramming and barrier dysfunction in eosinophilic esophagitis1R01AI184785-01A1 | RUFFNER, MELANIE A | CHILDREN'S HOSP OF PHILADELPHIA, PA | $3,375,359 | DNPD |
| 2025 | Structure-Function Analysis of Mxra8 Interaction with Alphaviruses2R01AI143673-06A1 | DIAMOND, MICHAEL SFREMONT, DAVED H. | WASHINGTON UNIVERSITY, MO | $3,371,896 | MCV |
| 2025 | Functional and Mechanistic Characterization of Lupus Susceptibility1R01AI191517-01A1 | NATH, SWAPAN K. | OKLAHOMA MEDICAL RESEARCH FOUNDATION, OK | $3,364,935 | ZRG1 |
| 2025 | Defining short RNA therapeutics that combat TDP-43 proteinopathy connected to AD and ADRDs.1RF1AG090910-01A1 | DONNELLY, CHRISTOPHER JAMESKALB, ROBERT GSHORTER, JAMES | UNIVERSITY OF PENNSYLVANIA, PA | $3,360,074 | DMPB |
| 2025 | Parent-child transmission of trauma in a longitudinal cohort: impact on aging-related mental and physical health well-being1RF1AG088719-01A1 | CHESLACK-POSTAVA, KEELY RHOVEN, CHRISTINA W. | NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY | $3,355,744 | SEDH |
| 2025 | Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL)2RF1AG058266-06 | SHANAFELT, TAIT DSLAGER, SUSAN L | MAYO CLINIC ROCHESTER, MN | $3,354,111 | CHD |
| 2025 | Regulated cGAS activation in HSV-1-associated neuropathogenesis.1RF1AG088625-01A1 | FENG, PINGHUI | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $3,354,022 | CNBT |
| 2025 | Developing Inhibitors of Seasonal and Pandemic Influenza Viruses1R01AI193216-01 | PAINTER, GEORGE ROBERTPLEMPER, RICHARD K. | GEORGIA STATE UNIVERSITY, GA | $3,352,410 | ATB |
| 2025 | Advancing rare disease discovery through technological and methodological approaches using an intuitive platform, seqr1R01HG013986-01A1 | O'DONNELL-LURIA, ANNEREHM, HEIDI L | BROAD INSTITUTE, INC., MA | $3,349,527 | GCAT |
| 2025 | Periodontitis Role in Inflammatory Bowel Disease1R01DK140281-01A1 | THUMBIGERE-MATH, VIVEK | UNIVERSITY OF MARYLAND BALTIMORE, MD | $3,340,009 | ZRG1 |
| 2025 | Toward development of senolytic CAR T cells2RF1AG065396-06A1 | LOWE, SCOTT W.SADELAIN, MICHEL WJ | SLOAN-KETTERING INST CAN RESEARCH, NY | $3,326,400 | CMAD |
| 2025 | Investigating aberrant vesicular degradation and lipid metabolism in neurodegeneration1RF1NS140600-01A1 | BOSCO, DARYL ANGELAMASSI, FRANCESCA | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $3,323,710 | CMND |
| 2025 | Microbial Determinants of Excessive Inflammation and Severe Lyme Disease1R01AI181904-01A1 | STRLE, KLEMEN | TUFTS UNIVERSITY BOSTON, MA | $3,315,179 | BHI |
| 2025 | Longitudinal Study of Cognitive and Biological Aging in Midlife and Older Sexual and Gender Minority Adults2RF1AG063771-06 | MCKAY, TARA | VANDERBILT UNIVERSITY, TN | $3,314,261 | SSPA |
| 2025 | Early Life Adversity, Cumulative Life Stress, and Cellular Aging in Midlife Women and Offspring1RF1AG094985-01 | EPEL, ELISSA S.LARAIA, BARBARA A | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $3,304,237 | MESH |
| 2025 | The uptake and real-world effectiveness of emerging respiratory syncytial virus maternal vaccines and monoclonal antibodies on short- and long-term respiratory morbidities1R01AI187287-01A1 | WU, PINGSHENG | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $3,304,164 | PRID |
| 2025 | Multimodal PET-CT imaging of SIVmac239 dynamics post-ART interruption1R01AI195422-01 | HENRICH, TIMOTHY JENSENOKOYE, AFAMEFUNAVANBROCKLIN, HENRY F. | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $3,302,677 | ZRG1 |
| 2025 | Prefrontal mechanisms of social interaction strategy1RF1MH138396-01A1 | CHANG, STEVE W. C.JADI, MONIKA P.NANDY, ANIRVAN S. | YALE UNIVERSITY, CT | $3,299,818 | BRLE |
| 2025 | Inhibition of Abeta42 aggregation by helix stabilizing peptidomimetic biomaterials1RF1AG094856-01 | CAI, JIANFENGZHU, DONGHUI | UNIVERSITY OF SOUTH FLORIDA, FL | $3,297,926 | BMBI |
| 2025 | Extracellular Vesicle treatment and age-related neuropathology in non-human primates2RF1AG068168-06 | MOORE, TARA L | BOSTON UNIVERSITY MEDICAL CAMPUS, MA | $3,284,677 | ASG |
| 2025 | Role of Ubiquitin Ligases and Deubiquitinases in Host Defense against Mycobacterium tuberculosis1R01AI187291-01A1 | SHILOH, MICHAEL | UT SOUTHWESTERN MEDICAL CENTER, TX | $3,278,392 | ZRG1 |
| 2025 | Dyadic Health Consequences of Distress in Patients and their Partners After an Acute Cardiovascular Event1RF1AG095092-01 | CORNELIUS, TALEA | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $3,273,481 | SPIP |
| 2025 | Mechanisms of nuclear egress in herpesviruses1R01AI192496-01 | HELDWEIN, EKATERINA | TUFTS UNIVERSITY BOSTON, MA | $3,268,792 | MCV |
| 2025 | Immune Activation and Region-specific Myocardial Arrhythmic Substrate in Sudden Cardiac Death Victims with HIV1R01HL178399-01A1 | HENRICH, TIMOTHY JENSENTSENG, ZIAN H | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $3,264,423 | HCCS |
| 2025 | Neurogenomics of Vulnerability and Resilience to Mental Health Syndromes in Response to Extreme Life Events2RF1MH118203-06A1 | MONTAGUE, MICHAEL JAMESPLATT, MICHAEL LSNYDER-MACKLER, NOAH | UNIVERSITY OF PENNSYLVANIA, PA | $3,263,217 | MESH |
| 2025 | Cortical Mechanisms of Innate Frequency Discrimination1R01DC022254-01A1 | ZAKHARENKO, STANISLAV S | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $3,262,585 | AUD |
| 2025 | Informing Drug Synergy: Investigating Mycobacterial Membrane Protein Structure and Function1R01AI187380-01A1 | REGO, ELIZABETH HESPERSTROUD, ROBERT M | YALE UNIVERSITY, CT | $3,262,539 | PCMB |
| 2025 | The role of macrophages in weight loss-induced metabolic health and adipose tissue inflammation resolution1R01DK140331-01A1 | WEINSTOCK, ADA | UNIVERSITY OF CHICAGO, IL | $3,255,832 | HSDO |
| 2025 | Indoles from commensal microbiota promote mobility during aging1RF1AG086417-01A1 | BENIAN, GUY MARTINKALMAN, DANIEL | EMORY UNIVERSITY, GA | $3,251,767 | CMAD |
| 2025 | Vaccine-mediated cross-alphavirus protection for a live attenuated FDA licensed chikungunya virus vaccine1R01AI188897-01A1 | COFFEY, LARK LSTREBLOW, DANIEL N | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $3,248,576 | ZRG1 |
| 2025 | METABOLIC ALDEHYDES AS IMMUNE EFFECTORS AGAINST TUBERCULOSIS2R01AI153197-06 | DARWIN, KATERINA HERANSTANLEY, SARAH A | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $3,246,637 | BHI |
| 2025 | Role of Neutrophils in the Pathogenesis of Cholangiopathies1R01DK142076-01A1 | NATHANSON, MICHAEL HSTRAZZABOSCO, MARIO | YALE UNIVERSITY, CT | $3,233,421 | HBPP |
| 2025 | Mitochondrial dysfunction driven by splicing factor mutations in MDS1R01DK141594-01A1 | KLEIN, PETER SWALLACE, DOUGLAS CXING, YI | UNIVERSITY OF PENNSYLVANIA, PA | $3,227,502 | BBHV |
| 2025 | Role of the Retrosplenial Cortex in the Progression of AD Pathogenesis in Mouse and Human1RF1AG090712-01A1 | BEIER, KEVIN THEAD, ELIZABETH | UNIVERSITY OF CALIFORNIA-IRVINE, CA | $3,221,450 | ZRG1 |
| 2025 | Characterization of Antigen-Specific Immune Response in ALS1RF1NS142171-01 | ELYAMAN, WASSIMJIANG, NING JENNYSHNEIDER, NEIL ALANSTERN, LAWRENCE J. | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $3,213,011 | ZRG1 |
| 2025 | Real-Time Detection of Staphylococcus aureus Transmission in Hospital Settings1R01AI193629-01 | RENSON, AUDREYSHOPSIN, BO | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $3,210,845 | ASPB |
| 2025 | Defining human and mouse non-canonical inflammasome responses to LPS1R01AI194573-01 | BRODSKY, IGOR ESHIN, SUNNY | UNIVERSITY OF PENNSYLVANIA, PA | $3,204,624 | ZRG1 |
| 2025 | Mechanisms of Fecal Microbiota Transplant Protection from Recurrent C. difficile2R01AI152477-06 | PETRI, WILLIAM ARAMAKRISHNAN, GIRIJA | UNIVERSITY OF VIRGINIA, VA | $3,202,592 | ZRG1 |
| 2025 | Investigating Extrachromosomal DNA (ecDNA) Segregation and Repair in Cancer1R01CA304441-01 | MACIEJOWSKI, JOHNSFEIR, AGNEL | SLOAN-KETTERING INST CAN RESEARCH, NY | $3,201,530 | CG |
| 2025 | Glomerular Cell-Cell Crosstalk and Injury2R01DK097253-11 | DAEHN, ILSE SOFIA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $3,196,256 | PBKD |
| 2025 | Roles and regulation of tissue resident CD8 T cells during a persistent viral infection1R01AI187302-01 | CHANG, JOHN TZUNIGA, ELINA I | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,194,992 | VPI |
| 2025 | Immunomodulation in AAV gene therapy1R01AI194953-01 | ASOKAN, ARAVIND | DUKE UNIVERSITY, NC | $3,192,404 | ZRG1 |
| 2025 | Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza response1R01AI186386-01A1 | OH, JULIAOZBOLAT, IBRAHIM | DUKE UNIVERSITY, NC | $3,182,827 | ZRG1 |
| 2025 | Natural killer cells subvert immune checkpoint therapy of tumors1R01CA303538-01 | YOKOYAMA, WAYNE M. | WASHINGTON UNIVERSITY, MO | $3,182,665 | TIR |
| 2025 | Intestinal proteases in alcohol-associated liver disease1R01AA031710-01A1 | SCHNABL, BERND G. | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,182,397 | HBPP |
| 2025 | Residential Greenness, Airway Microbiome,and Incident Childhood Asthma1R01ES036966-01A1 | ZHU, ZHAOZHONG | MASSACHUSETTS GENERAL HOSPITAL, MA | $3,181,155 | ZRG1 |
| 2025 | Investigation of Yop activities in M cells during murine infection1R01AI184990-01A1 | MECSAS, JOAN C | TUFTS UNIVERSITY BOSTON, MA | $3,178,626 | BHI |
| 2025 | Novel macrophage mediated signals regulate the immunoregulatory environment of the neonatal liver1R01DK143079-01 | NIJAGAL, AMAR | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $3,176,680 | HBPP |
| 2025 | Development and optimization of a peptide inhibitor of influenza virus splicing for broad-spectrum antiviral therapy1R01AI181944-01A1 | TENOEVER, BENJAMIN R. | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $3,170,096 | DMPA |
| 2025 | A translational approach for novel precision medicine models1R01AA031505-01A1 | MARMAR, CHARLES RNASCA, CARLA | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $3,168,729 | NAL |
| 2025 | Advancing Targeted Therapies for Cushing's Disease Using Pituitary Neuroendocrine Tumor Organoids1R01DK138306-01A1 | LITTLE, ANDREW SCOTTZAVROS, YANA | UNIVERSITY OF GEORGIA, GA | $3,162,826 | ICER |
| 2025 | Transmission dynamics and fitness of reemerging St. Louis encephalitis virus in mosquito vectors and West Nile virus naïve and immune avian reservoirs1R01AI194449-01 | BOSCO-LAUTH, ANGELA MARIAHCOFFEY, LARK L | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $3,161,373 | TVZ |
| 2025 | Biomechanical Optimization of Mitral Valve Repair Operations2R01HL152155-05A1 | WOO, Y JOSEPH | STANFORD UNIVERSITY, CA | $3,153,055 | BTSS |
| 2025 | Upstream pathogenesis in familial and sporadic frontotemporal dementia and motor neuron disease2RF1NS104437-06 | SEELEY, WILLIAM W | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $3,153,019 | ZRG1 |
| 2025 | Dendritic cell intrinsic UPR is critical for pathogen specific Th17 responses1R01AI184441-01A1 | HERR, ANDREW BPASARE, CHANDRASHEKHAR | CINCINNATI CHILDRENS HOSP MED CTR, OH | $3,147,392 | IIB |
| 2025 | Macrophage senescence as a driver of granuloma failure and progression to necrosis in TB and TB/HIV1R01AI189410-01A1 | BISHAI, WILLIAM RAMSESKRAMNIK, IGOR | JOHNS HOPKINS UNIVERSITY, MD | $3,145,850 | HCAC |
| 2025 | Real world use of anti-obesity medications to treat adolescent obesity: moving beyond the clinical trial1R01DK142666-01A1 | NESHTERUK, CODY | DUKE UNIVERSITY, NC | $3,145,056 | BMHO |
| 2025 | Harnessing Novel Human Endocrine Progenitor Biology for Enhanced Generation of Beta Cells from Stem Cells1R01DK144425-01 | SNEDDON, JULIE BETH | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $3,140,632 | BMDM |
| 2025 | Adverse Health Outcomes From Extreme Heat, Air Pollution, and Medications in Low-Income Pregnant Women and Their Offspring1R01HD114056-01A1 | SETOGUCHI IWATA, SOKO | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $3,140,397 | ZRG1 |
| 2025 | Human neuropeptide transmitter systems are dysregulated in Alzheimer's disease pathogenesis1RF1AG095193-01 | HOOK, VIVIAN Y. H | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,138,871 | ASG |
| 2025 | Integrating the exposome and epigenome identifies determinants of ALS risk, survival, and pathogenesis1R01ES037968-01 | BATTERMAN, STUART AFELDMAN, EVA LUCILLEGOUTMAN, STEPHENSARTOR, MAUREEN AGNES | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $3,133,754 | CNTN |
| 2025 | Advancing the Study of Personality, Interpersonal Stress, and Cognitive Aging Through The Use of Integrative Data Analysis1RF1AG094591-01 | GRAHAM, EILEEN KRANZLUO, JING | NORTHWESTERN UNIVERSITY, IL | $3,132,978 | SPIP |
| 2025 | Lymphoid-specific high-efficiency beta-catenin protein degradation1R01AI192914-01 | MÜSCHEN, MARKUS | YALE UNIVERSITY, CT | $3,131,408 | MSI |
| 2025 | Resolving the mechanisms of IFIH1 risk variant in systemic lupus erythematosus1R01AI190169-01 | GORMAN, JACQUELYN | OKLAHOMA MEDICAL RESEARCH FOUNDATION, OK | $3,130,679 | MAI |
| 2025 | The Ecology of Barrett's Esophagus1R01CA285517-01A1 | MALEY, CARLOYUAN, YINYIN | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $3,130,492 | BDMA |
| 2025 | Targeting a novel inter-tissue L-BAIBA/FGF23 axis to enhance adaptive musculoskeletal remodeling in aging1RF1AG088242-01A1 | WELC, STEVEN SWHITE, KENNETH E | INDIANA UNIVERSITY INDIANAPOLIS, IN | $3,126,515 | SBSR |
| 2025 | Optimizing anti-microbial immunity by targeting Sts-11R01AI177367-01A1 | CARPINO, NICHOLAS AFRENCH, JARROD B | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $3,125,627 | ZRG1 |
| 2025 | PFAS exposure is detrimental to placental function and fetal development by disrupting mitochondrial function and metabolism1R01ES036951-01A1 | FENG, LIPING | DUKE UNIVERSITY, NC | $3,121,590 | PN |
| 2025 | Assessment of Speech Sound Disorders in Bilingual Latino Children: An Evidence-Based Procedure1R01DC022867-01 | FABIANO, LEAH CATHERINE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $3,116,157 | LCOM |
| 2025 | TYK2 Fusions in Lymphoma1R01CA297080-01A1 | ELENITOBA-JOHNSON, KOJO S. J. | SLOAN-KETTERING INST CAN RESEARCH, NY | $3,111,184 | BCO |
| 2025 | Next-Generation CMA/CMB Derivatives as Targeted Inhibitors of HIV Nef1R01AI194902-01 | COLLINS, KATHLEEN L.SHERMAN, DAVID H | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $3,110,884 | HVCD |
| 2025 | Evaluation of the Mechanisms Underlying Induction and Maintenance Immunosuppression Impact on T Cell Function after Kidney Transplantation1R01AI187989-01A1 | SCHAENMAN, JOANNA M | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $3,106,301 | ITA |
| 2025 | Role of Lipogenic Pathways in Intestinal Remodeling after Gastric Bypass Surgery1R01DK139157-01A1 | STEFATER-RICHARDS, MARGARET | BOSTON CHILDREN'S HOSPITAL, MA | $3,103,125 | HSDO |
| 2025 | A beneficial persistent DNA damage-induced immune response in aging1RF1AG093995-01 | DU, WEI | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $3,101,237 | ZRG1 |
| 2025 | O-GLCNAC HOMEOSTASIS REGULATES MITOCHONDRIAL FUNCTION IN ALZHEIMER'S DISEASE2RF1AG064227-06 | SLAWSON, CHAD ERIC | UNIVERSITY OF KANSAS MEDICAL CENTER, KS | $3,088,152 | NOMD |
| 2025 | Single molecule study of C9ORF72 repeat RNA metabolisms in ALS/FTD2RF1NS113820-02 | SUN, SHUYINGWU, BIN | JOHNS HOPKINS UNIVERSITY, MD | $3,085,325 | CMND |
| 2025 | The role of cryptic influenza virus proteins in replication and pathogenesis1R01AI187065-01A1 | MEHLE, ANDREW | UNIVERSITY OF WISCONSIN-MADISON, WI | $3,085,097 | MCV |
| 2025 | Optimizing lipid RVn monophosphate prodrugs to maximize RVn-triphosphate delivery1R01AI187899-01A1 | CARLIN, AARON F. | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,082,513 | ATB |
| 2025 | Discovery of Gene-by-Air Pollution Interactions in Respiratory Disease using Genetically Diverse Mice with Validation in Humans1R01ES036998-01A1 | KELADA, SAMIR | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $3,082,011 | GHD |
| 2025 | Mechanism of ALS/FTD determined by multimodal single cell spatial transcriptomics1RF1NS144660-01 | BINTU, BOGDANCLEVELAND, DON WRAVITS, JOHN | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,081,936 | CMND |
| 2025 | Determinants of follicular helper T cell expansion in lupus2R01AI154630-06 | MOREL, LAURENCEZADEH, MANSOUR M | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX | $3,080,796 | ZRG1 |
| 2025 | Statistical Machine Learning to Develop Connectome-Based Biomarkers of Alzheimer's Disease and Related Dementias1RF1AG090462-01A1 | SAFIKHANI, ABOLFAZLSHOJAIE, ALI | UNIVERSITY OF WASHINGTON, WA | $3,080,520 | ASPA |
| 2025 | Mapping genetic vulnerability to oxidative stress in development and its consequences in age-associated cognitive decline using a novel reduced complexity rat model1RF1AG091181-01A1 | BAJWA, AMANDEEPCHEN, HAOMULLIGAN, MEGAN KATHLEEN | UNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN | $3,078,607 | GHD |
| 2025 | Transcriptional co-regulators and macrophage gene expression2R01DK091183-35 | GLASS, CHRISTOPHER K | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,078,559 | CSME |
| 2025 | TCR-dependent and epigenetic mechanisms guiding influenza-specific CD4+ T cell responses in the lung1R01AI194555-01 | HALE, JEFFREY SCOTTWILLIAMS, MATTHEW A | UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT | $3,078,308 | IHD |
| 2025 | Airway Innate Immune Responses to Coccidioides Infection1R01AI188584-01A1 | CHEN, YINDI, YUANPU PETER | UNIVERSITY OF ARIZONA, AZ | $3,075,549 | LII |
| 2025 | Mechanism of stathmin-2-dependent axon maintenance, regeneration, and function2R37NS112503-07 | CLEVELAND, DON WLAGIER-TOURENNE, CLOTILDE | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,072,075 | CMND |
| 2025 | Activation of Macrophages in Human Autoimmune Diseases2R01AI046712-26 | IVASHKIV, LIONEL B | HOSPITAL FOR SPECIAL SURGERY, NY | $3,071,328 | ZRG1 |
| 2025 | Role of the Cell Death Machinery in a Somatic Autoinflammatory Syndrome1R01AI187249-01A1 | GITLIN, ALEXANDER | SLOAN-KETTERING INST CAN RESEARCH, NY | $3,066,524 | IIB |
| 2025 | Engineered metabolite-based nanoparticles for immunomodulation of macrophages to treat obesity1R01DK144500-01 | HASSANI NAJAFABADI, ALIREZA | TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION, CA | $3,065,252 | INN |
| 2025 | Anxiety and depression in a nonhuman primate model of synucleinopathy1RF1NS138787-01A1 | EMBORG, MARINAKALIN, NED H | UNIVERSITY OF WISCONSIN-MADISON, WI | $3,064,072 | CDIN |
| 2025 | Efflux Route Responses of Cerebral Waste Clearance During Progression of Alzheimer’s Disease1RF1AG094722-01 | JIANG, QUANZHANG, LI | HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI | $3,062,355 | ITN |
| 2025 | Form with function: Rapid phenotypic carbapenemase testing to improve detection of carbapenemase-producing organisms1R01AI182314-01A1 | COLLINS, MATTHEWMYERS, DAVID RICHARD | EMORY UNIVERSITY, GA | $3,055,197 | EDIT |
| 2025 | RNA modifications in apolipoprotein regulation by environmental exposures1R01ES036210-01A1 | CAVE, MATTHEW CKLINGE, CAROLYN M. | UNIVERSITY OF LOUISVILLE, KY | $3,051,769 | EDD |
| 2025 | Paired receptor signaling for NK cell virus control and antiviral immunity1R01AI189798-01 | BROWN, MICHAEL G. | UNIVERSITY OF VIRGINIA, VA | $3,047,991 | IHD |
| 2025 | Molecular mechanisms of enterovirus D68 viral entry mediated by the MFSD6 receptor1R01AI193097-01 | CARETTE, JAN E | STANFORD UNIVERSITY, CA | $3,045,291 | VDT |
| 2025 | Controllable solid tumor immunotherapy based on a wireless thermos-activator1R01CA304704-01 | WANG, YINGXIAOYU, CUNJIANG | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $3,036,844 | ISD |
| 2025 | Study the Treg-IL-27 axis in immune regulation1R01AI188710-01 | CHU, HIUTUNGLU, LI-FAN | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,022,197 | CMIA |
| 2025 | Role of branched-chain fatty acids in physiology and virulence of Staphylococcus aureus1R01AI187253-01A1 | BRINSMADE, SHAUN R | GEORGETOWN UNIVERSITY, DC | $3,021,822 | BV |
| 2025 | Deciphering the Role of Chemokine Receptor CCR5 in Maternal Flavivirus Infections1R01AI188432-01A1 | LIM, JEAN KYOU | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $3,021,038 | PN |
| 2025 | Contributions of BRWD1-mediated cohesin conversion to B cell biology1R01AI187357-01A1 | CLARK, MARCUS RAMSAYMANDAL, MALAY | UNIVERSITY OF CHICAGO, IL | $3,018,216 | AI |
| 2025 | Design of single-shot sequential immunization regimens for HIV using atomic layer deposition technology.1R01AI192197-01 | FLYNN, CLAUDIAIRVINE, DARRELL JRANDOLPH, THEODORE WSCHIEF, WILLIAM R. | SCRIPPS RESEARCH INSTITUTE, THE, CA | $3,017,032 | HIVD |
| 2025 | Dietary Fiber-Microbiome Interactions: Elucidating Mechanisms to Suppress Multi-Drug Resistant Organisms in the Human Gut1R01AI194497-01 | SAFDAR, NASIAVENTURELLI, OPHELIA | DUKE UNIVERSITY, NC | $3,012,181 | ZRG1 |
| 2025 | Mitoprotective therapies for kidney injury1R01DK142433-01 | BAJWA, AMANDEEPPABLA, NAVJOT | UNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN | $3,010,432 | ZRG1 |
| 2025 | Cell-Type Specific Mechanisms of Mitral Valve Prolapse1R01HL180627-01 | CHI, NEIL C | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $3,008,247 | CCHS |
| 2025 | MECHANISMS OF AGE-and SEX- DEPENDENT CHANGES IN URINARY BLADDER IMMUNITY1R01DK144139-01 | MYSOREKAR, INDIRA U | BAYLOR COLLEGE OF MEDICINE, TX | $3,005,541 | KUFD |
| 2025 | Maternal microbial exposure fundamentally shapes the CD8 T cell population at the maternal fetal interface1R01AI189469-01 | SCHULDT, NATHAN | UNIVERSITY OF MINNESOTA, MN | $2,999,774 | IHD |
| 2025 | Regulation of mitochondrial health in mammalian livers.1R01DK144133-01 | MISHRA, PRASHANT | UT SOUTHWESTERN MEDICAL CENTER, TX | $2,999,512 | HBPP |
| 2025 | Reactive oxygen species as early-in-life modulators of lifespan1RF1AG094801-01 | JAKOB, URSULA H. | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $2,991,725 | CMAD |
| 2025 | Trends and outcomes of lung cancer screening among people with and without HIV in the US1R01CA302303-01 | ISLAM, JESSICA YASMINE | H. LEE MOFFITT CANCER CTR & RES INST, FL | $2,991,283 | PPAH |
| 2025 | Pyrimidine metabolism in the development of autoreactive B cells and SLE1R01AI194568-01 | RAHMAN, ZIAUR | THOMAS JEFFERSON UNIVERSITY, PA | $2,989,958 | ZRG1 |
| 2025 | Characterizing Newly Identified Human Cytomegalovirus Entry Receptors1R01AI187580-01A1 | JARDETZKY, THEODORE SJOHNSON, DAVID C. | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $2,989,013 | MCV |
| 2025 | Comprehensive Liquid Biomarkers to Personalize Therapy in Renal Cell Carcinoma1R01CA292799-01A1 | MCKAY, RANA RAMZI | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $2,984,495 | MCDC |
| 2025 | Impact of Asymptomatic CMV on Cardiovascular Event Risk in Treated HIV1R01HL180319-01 | HUNT, PETER W | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $2,981,544 | HCCS |
| 2025 | Epigenetic mechanisms enhancing transcriptional response to environmental heat stress1R01ES037774-01 | WU, CARL | JOHNS HOPKINS UNIVERSITY, MD | $2,979,007 | MG |
| 2025 | Targeting hepatic stellate cell metabolism to treat steatotic liver disease2R01DK104735-10A1 | FINCK, BRIAN N | WASHINGTON UNIVERSITY, MO | $2,978,209 | CSME |
| 2025 | Exploring polyamine toxicity and resistance in epidemic bacterial skin pathogens1R01AI187165-01A1 | RICHARDSON, ANTHONY R. | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $2,976,652 | BV |
| 2025 | Translational control underlies nutrition and metabolism in health and disease1R01DK141469-01A1 | RUGGERO, DAVIDE | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $2,971,227 | NMHD |
| 2025 | Developmental programming of adult stem cells1R01DK143944-01 | MANA, MIYEKO | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $2,970,076 | DNPD |
| 2025 | Somatic Truncation Mutations of the Histone Methyltransferase MLL4 Alter Its Subcellular Localization in Bladder Cancer: Mechanistic Insight and Targeted Therapeutic Approach1R01CA298333-01A1 | MEEKS, JOSHUA JAMESSHILATIFARD, ALI | NORTHWESTERN UNIVERSITY, IL | $2,970,010 | ATA |
| 2025 | Activating Autophagy to Treat Uromodulin-Associated Genetic Chronic Kidney Disease2R01DK105056-06 | CHEN, YING MAGGIE | WASHINGTON UNIVERSITY, MO | $2,969,015 | PBKD |
| 2025 | Novel role of urinary urate in renal cystogenesis and water regulation1R01DK142878-01 | CHEBIB, FOUAD T | MAYO CLINIC JACKSONVILLE, FL | $2,967,657 | PBKD |
| 2025 | The Role of the MBD2-NuRD Complex in Gamma-Globin Gene Silencing2R01DK115563-06A1 | GINDER, GORDON DWILLIAMS, DAVID COLLIN | VIRGINIA COMMONWEALTH UNIVERSITY, VA | $2,965,140 | BBHV |
| 2025 | Cystoscopy-augmenting tools to improve the sensitivity and specificity of detection of urothelial carcinoma in situ1R01CA301464-01A1 | BOWDEN, AUDREY KYNSELLA | VANDERBILT UNIVERSITY, TN | $2,958,465 | ZRG1 |
| 2025 | Understanding resistance and tolerance to nitroimidazoles in Mycobacterium tuberculosis1R01AI192524-01 | EHRT, SABINESCHNAPPINGER, DIRK | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $2,944,529 | AIRT |
| 2025 | Global Brain Health Predictors of Post-Stroke Sensorimotor Recovery using AI-Enhanced Clinical MRIs2RF1NS115845-06A1 | LIEW, SOOK-LEI | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $2,942,690 | MRS |
| 2025 | Host cell reprogramming by human papillomavirus E7 proteins1R01AI187203-01A1 | MUNGER, KARLWHITE, ELIZABETH A | TUFTS UNIVERSITY BOSTON, MA | $2,938,414 | MCV |
| 2025 | ACE2 immunodecoys for long-lasting immunoprophylaxis against sarbecovirus and merbecoviruses that target human ACE21R01AI175536-01A1 | LAI, SAMUELPICKLES, RAYMOND J | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $2,937,578 | VID |
| 2025 | Neurophysiological Genetics of Binge Drinking1R01AA031496-01A1 | LINSENBARDT, DAVID NATHANIEL | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM | $2,927,529 | NAL |
| 2025 | Advancing Apoptosis-Inducing Agents as Host-Directed Therapy for TB1R01AI186308-01A1 | HAMACHER-BRADY, ANNEJAIN, SANJAY KKARAKOUSIS, PETROS C | JOHNS HOPKINS UNIVERSITY, MD | $2,922,220 | BHI |
| 2025 | Role of norovirus capsid dynamics in adaptive immune evasion1R01AI189484-01 | SMITH, THOMAS JAMES.WOBUS, CHRISTIANE | UNIVERSITY OF TEXAS MED BR GALVESTON, TX | $2,920,356 | MSFC |
| 2025 | CHROME: Continuum of HIV Response through Observational Molecular Epidemiology1R01AI192139-01 | WERTHEIM, JOEL OKRENT | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $2,911,005 | PPAH |
| 2025 | Midbrain Signals for Differential Reinforcement Learning1RF1MH141903-01 | APOSTOLIDES, PIERRE F | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $2,908,921 | ZRG1 |
| 2025 | Targeting PDGFR-b promoter vacancy G-quadruplex to suppress gene expression1R01CA296831-01A1 | YANG, DANZHOU | PURDUE UNIVERSITY, IN | $2,906,409 | MSFB |
| 2025 | Development of a Virtual Preclinical CT Platform for Advanced Imaging and Theranostics in Head and Neck Cancer Research1R01CA302738-01 | BADEA, CRISTIAN TLAFATA, KYLESEGARS, WILLIAM P | DUKE UNIVERSITY, NC | $2,896,024 | EITA |
| 2025 | Understanding and targeting epigentic regulation of immune evasion in prostate cancer1R01CA296203-01A1 | CAI, LINGWANG, G GREG | DUKE UNIVERSITY, NC | $2,895,540 | GRIC |
| 2025 | Dietary fat-activated colonocyte-macrophage ketone shuttle drives intestinal inflammation1R01AI177584-01A1 | CRAWFORD, PETER AREVELO, XAVIERRUAN, HAI-BIN | UNIVERSITY OF MINNESOTA, MN | $2,893,480 | DHMI |
| 2025 | Clostridioides difficile Zinc-binding PBPs as anti-sporulation targets1R01AI185760-01A1 | CHEN, YUSUN, XINGMIN | UNIVERSITY OF SOUTH FLORIDA, FL | $2,872,722 | MSFA |
| 2025 | Effect of APOE on CNS Neurons: Role of LRP2RF1NS090934-25A1 | HOLTZMAN, DAVID M. | WASHINGTON UNIVERSITY, MO | $2,868,920 | CDIN |
| 2025 | AI for Differentiation of Low vs High Risk Thyroid Nodules on Ultrasound1R01CA297227-01A1 | MAZUROWSKI, MACIEJ A.WILDMAN-TOBRINER, BENJAMIN | DUKE UNIVERSITY, NC | $2,867,231 | EITA |
| 2025 | Mechanisms of CD4 T cell help to myeloid cells in tuberculosis1R01AI193512-01 | BOLD, TYLER DALLAS | UNIVERSITY OF MINNESOTA, MN | $2,863,501 | IHD |
| 2025 | Modeling effects of cadmium exposure on Alzheimer’s Disease pathology and neurodegeneration1RF1AG090456-01A1 | COMBS, BENJAMIN NEALSAMMI, SHREESH RAJ | HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI | $2,862,804 | NAL |
| 2025 | Computational Methods for Gene Discovery, Genome Annotation, and Genome Assembly2R01HG006677-24 | SALZBERG, STEVEN L. | JOHNS HOPKINS UNIVERSITY, MD | $2,842,773 | ZRG1 |
| 2025 | Genetic regulation of epithlial injury in ulcerative colitis1R01DK141679-01 | KATTAH, MICHAEL GEORGE | MAYO CLINIC ROCHESTER, MN | $2,842,245 | DHMI |
| 2025 | Bacterial cell wall remodeling, innate immunity, and pathogenesis1R01AI194356-01 | ALONZO, FRANCIS | UNIVERSITY OF ILLINOIS AT CHICAGO, IL | $2,841,668 | ZRG1 |
| 2025 | Impact of CAR and Nrf2 dual activation on cyclophosphamide bioactivation and doxorubicin detoxification1R01CA295603-01A1 | WANG, HONGBINGXUE, FENGTIAN | UNIVERSITY OF MARYLAND BALTIMORE, MD | $2,840,768 | DBDT |
| 2025 | Renal Metabolism in AKI1R01DK141973-01A1 | SINGH, PRABHLEEN | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $2,833,514 | PBKD |
| 2025 | Metabolic Regulation by SAPS3 of Virus-specific T cell Immunity1R01AI187458-01A1 | KONG, MEITINOCO, ROBERTO | UNIVERSITY OF CALIFORNIA-IRVINE, CA | $2,832,747 | IHD |
| 2025 | The relationship between ocus-coeruleus-norepinephrine network and neurovascular coupling in health and disease1RF1NS137980-01A1 | TRAN, CAM HA THAI | UNIVERSITY OF NEVADA RENO, NV | $2,813,759 | ZRG1 |
| 2025 | Genetic and mechanistic analysis of carbon dioxide tolerance in Cryptococcus pathogenesis2R01AI147541-06 | KRYSAN, DAMIAN JLIN, XIAORONG | UNIVERSITY OF IOWA, IA | $2,811,266 | PTHE |
| 2025 | Engineered Gene Circuits for Basic Science and Biotechnology2R01GM069811-21A1 | HASTY, JEFF MTSIMRING, LEV S | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $2,803,612 | MABS |
| 2025 | High-throughput interrogation of long-range enhancers1R01HG014139-01 | COHEN, BARAK A | WASHINGTON UNIVERSITY, MO | $2,796,648 | GCAT |
| 2025 | Vertically transferred antibodies protect babies from Escherichia coli infection1R01AI189741-01 | WAY, SING SING | CINCINNATI CHILDRENS HOSP MED CTR, OH | $2,790,604 | IHD |
| 2025 | Molecular mechanism of metabolic stress in the pancreatic beta cells1R01DK141852-01A1 | WANG, YUE | FLORIDA STATE UNIVERSITY, FL | $2,782,476 | BMDM |
| 2025 | Understanding Hirschsprung disease using hPSC-derived models of the enteric nervous system1R01DK142437-01A1 | FATTAHI, FARANAK | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $2,781,801 | ZRG1 |
| 2025 | The Vascular Fibroblast: An Understudied Culprit In Postoperative Venous Stenosis1R01DK144860-01 | MARTINEZ, LAISEL | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL | $2,777,206 | KUFD |
| 2025 | Measuring social needs among older adults: psychometrics and policy1RF1AG095083-01 | UNRUH, MARK AARONVEST, JOSHUA RYAN | INDIANA UNIVERSITY INDIANAPOLIS, IN | $2,776,875 | ZRG1 |
| 2025 | Mycoestrogens and maternal-child health in the TIDES cohort1R01ES037903-01 | BARRETT, EMILY SRIVERA-NUNEZ, ZORIMAR | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $2,774,390 | SEDH |
| 2025 | Social odor modulation of auditory cortex via the basal amygdala1R01DC022436-01A1 | SHEA, STEPHEN D | COLD SPRING HARBOR LABORATORY, NY | $2,774,362 | NIC |
| 2025 | Center for Critical Assessment of Structure Prediction (CASP)2R01GM100482-14 | FIDELIS, KRZYSZTOF A | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $2,772,905 | MSFA |
| 2025 | Algorithms and Software for the Assembly of Metagenomic Data2R01AI100947-09 | POP, MIHAI | UNIV OF MARYLAND, COLLEGE PARK, MD | $2,764,928 | BDMA |
| 2025 | Impacts of phthalate exposure on the development of social behavior circuits1R01ES036997-01A1 | BONTHUIS, PAUL JEFFREYGOENSE, JOZIENGRITTON, HOWARD | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $2,737,859 | NAL |
| 2025 | Genetic variation underlying innate lymphoid cell phenotypes across hosts1R01DK140446-01A1 | BANDO, JENNIFER KAORU | STANFORD UNIVERSITY, CA | $2,736,640 | DHMI |
| 2025 | Phage/Salmonella interactions during oxidative stress1R01AI190189-01 | VAZQUEZ-TORRES, ANDRES | UNIVERSITY OF COLORADO DENVER, CO | $2,727,148 | ZRG1 |
| 2025 | Supervised Weighted Distances: Patient Similarity to Explain Clinical AI Models1R01LM014163-01A1 | KUO, TSUNG-TINGOHNO-MACHADO, LUCILA | YALE UNIVERSITY, CT | $2,720,667 | CIDH |
| 2025 | Regulation of innate immunity by self-adjuvated MRNA vaccines1R01AI184394-01A1 | JAGANNATH, CHINNASWAMY | METHODIST HOSPITAL RESEARCH INSTITUTE, TX | $2,710,680 | VID |
| 2025 | Outcomes after Hospital Discharge to Home Versus Discharge to a Facility for Older Patients with Alzheimer’s Disease and Alzheimer’s Disease Related Dementias1RF1AG094784-01 | LY, DAN | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $2,709,669 | ZRG1 |
| 2025 | Striatal Interneuron Contributions to Behavioral Control1RF1MH138591-01A1 | FUCCILLO, MARC V | UNIVERSITY OF PENNSYLVANIA, PA | $2,693,038 | LMDN |
| 2025 | Mechanisms and Impact of NRG3 Induction in Bone Metastasis1R01CA300205-01 | BADO, IGOR LANDRY | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $2,691,173 | TEHM |
| 2025 | Regulation of neutrophil plasticity, heterogenicity, and functional ambivalency by WNT5 in colitis1R01AI181846-01A1 | WU, DIANQING | YALE UNIVERSITY, CT | $2,685,326 | III |
Showing the 200 most recent of 54,180 awards.
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.