Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

51 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Juliano, Rudolph

   Leads 3 awards · $5,028,737

   • 5U54CA119343-04Department: NIH department code

     Carolina Center of Cancer Nanotechnology Excellence
     $3,430,039

     award amount
   • 5P01GM059299-09Department: NIH department code

     The Pharmacodynamics of Genes and Oligonucleotides
     $1,255,598

     award amount
   • 5R01GM080981-02Department: NIH department code

     Enhanced Delivery of Protein Biosensors: a Combinatorial Library Strategy
     $343,100

     award amount

2. Samulski, Richard J

   Leads 4 awards · $3,915,031

   • 5P01HL051818-15Department: NIH department code

     Gene Therapy for Cystic Fibrosis
     $1,896,229

     award amount
   • 1U54AR056953-01Department: NIH department code

     Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center
     $1,491,322

     award amount
   • 1R01AI072176-01A1Department: NIH department code

     Rational and combinatorial engineering of AAV vectors
     $373,669

     award amount
   • 5R21AR055712-02Department: NIH department code

     Muscle-specific AAV Vectors for DMD Gene Therapy
     $153,811

     award amount

3. Crews, Fulton T

   Leads 3 awards · $2,403,478

   • 2P60AA011605-11Department: NIH department code

     Molecular and Cellular Pathogenesis in Alcoholism
     $1,800,001

     award amount
   • 5R01AA006069-23Department: NIH department code

     Ethanol Effects on Neurotransmission
     $338,599

     award amount
   • 2T32AA007573-11Department: NIH department code

     Molecular and Cellular Alcohol Research Training
     $264,878

     award amount

4. McLeod, Howard L

   Leads 1 award · $1,907,329

   • 5U01GM063340-08Department: NIH department code

     Functional Polymorphism Analysis in Drug Pathways
     $1,907,329

     award amount

5. Roth, Bryan L.

   Leads 2 awards · $1,610,900

   • 5U19MH082441-02Department: NIH department code

     Functional Selectivity: A Novel approach for CNS Drug Discovery
     $1,264,814

     award amount
   • 5R01MH061887-09Department: NIH department code

     Targeting and Trafficking of 5-HT2A serotonin Receptors
     $346,086

     award amount

6. Johnson, Gary L.

   Leads 5 awards · $1,242,780

   • 5R37GM030324-30Department: NIH department code

     RECEPTOR INTERACTION WITH GTP REGULATORY PROTEINS
     $420,330

     award amount
   • 5R01DK037871-26Department: NIH department code

     Regulation of Sequential Protein Kinase Pathways
     $321,930

     award amount
   • 2R01GM068820-05A1Department: NIH department code

     Function of MEKK3 and its osmosensing scaffold protein
     $316,714

     award amount
   • 3R01GM068820-05A1S1Department: NIH department code

     Function of MEKK3 and its osmosensing scaffold protein
     $110,656

     award amount
   • 1R24GM084756-01Department: NIH department code

     Defining Signal Network Plasticity
     $73,150

     award amount

7. Lee, Kuo-Hsiung

   Leads 3 awards · $1,187,308

   • 1R01AI077417-01Department: NIH department code

     Modified Triterpines as Potent HIV Fusion Inhibitors
     $464,297

     award amount
   • 5R01AI033066-17Department: NIH department code

     PLANT ANTI-HIV AGENTS
     $419,292

     award amount
   • 5R01CA017625-31Department: NIH department code

     PLANT ANTITUMOR AGENTS
     $303,719

     award amount

8. McCarthy, Ken Douglas

   Leads 4 awards · $1,184,972

   • 5R01NS033938-10Department: NIH department code

     Astrocytic Regulation of Neuronal Excitability in Vivo
     $356,958

     award amount
   • 5R01NS020212-23Department: NIH department code

     Neuronal-Astrocytic Communications In Vivo
     $324,353

     award amount
   • 1R01NS058904-01A1Department: NIH department code

     Role of Spinal Cord Lamina II Astrocytes in Neurophysiology and Chronic Pain
     $285,607

     award amount
   • 1R21HD058207-01Department: NIH department code

     Analysis of Genomic and Proteomic Changes in Glia That Lead To Hydrocephalus
     $218,054

     award amount

9. Der, Channing J.

   Leads 4 awards · $1,038,213

   • 5R01CA042978-22Department: NIH department code

     Biological activity of ras oncogenes
     $319,853

     award amount
   • 1R01CA129610-01A2Department: NIH department code

     Mechanism and role of DLC-1 tumor suppressor loss in lung cancer
     $300,879

     award amount
   • 5R01CA127152-02Department: NIH department code

     Role of RGS proteins in Ras- and B-Raf--mediated transformation
     $221,178

     award amount
   • 5T32CA071341-13Department: NIH department code

     Cancer Cell Biology Training Program
     $196,303

     award amount

10. Nicholas, Robert A

    Leads 3 awards · $930,325

    • 2R01HL071131-05A2Department: NIH department code

      Trafficking/signaling of P2Y receptors in polarized epithelial cells
      $364,498

      award amount
    • 5R01AI036901-13Department: NIH department code

      Mechanisms of antibiotic action in Neisseria gonorrhoeae.
      $347,681

      award amount
    • 5T32GM007040-34Department: NIH department code

      Predoctoral Training in Pharmacological Sciences
      $218,146

      award amount

11. Tropsha, Alexander

    Leads 3 awards · $868,677

    • 5R21GM076059-03Department: NIH department code

      Robust computational framework for predictive ADME-Tox modeling
      $322,087

      award amount
    • 2R01GM066940-05A1Department: NIH department code

      Predictive QSAR Modeling
      $282,141

      award amount
    • 5R01GM068665-03Department: NIH department code

      Protein Structure/Function Specific Packing Motifs
      $264,449

      award amount

12. Siderovski, David P.

    Leads 4 awards · $737,657

    • 5R01GM062338-08Department: NIH department code

      G-protein signal coordination by RGS12
      $258,751

      award amount
    • 5R01GM074268-03Department: NIH department code

      Mechanistic studies of a novel G-alpha nucleotide cycle
      $226,178

      award amount
    • 1R01GM082892-01A1Department: NIH department code

      Structural Determinants of Heterotrimeric G-protein Nucleotide Cycling
      $215,853

      award amount
    • 3R03NS053754-01S2Department: NIH department code

      Real-Time Fluorescence Assay:RGS Domain GAP Activit(RMI)
      $36,875

      award amount

13. Hahn, Klaus M.

    Leads 2 awards · $642,280

    • 2R01GM057464-09Department: NIH department code

      Dye-Based biosensors: simultaneous imaging of multiple protein activities
      $368,958

      award amount
    • 5R01GM082288-10Department: NIH department code

      Versatile scaffolds to visualize endogenous protein activation in living cells
      $273,322

      award amount

14. Huang, Leaf

    Leads 2 awards · $601,591

    • 1R01CA129421-01A1Department: NIH department code

      Interaction of cationic lipids with dendritic cells
      $301,380

      award amount
    • 1R01CA129835-01A1Department: NIH department code

      LPD Nanoparticles in Anti-Cancer Therapy
      $300,211

      award amount

15. Elston, Timothy C

    Leads 2 awards · $595,417

    • 5R01GM078994-03Department: NIH department code

      Cytoskeletal Oscillations: Mathematical Modeling Integrated with Experiments
      $311,885

      award amount
    • 5R01GM079271-03Department: NIH department code

      Spatiotemporal modeling of signal transduction in yeast
      $283,532

      award amount

16. Polleux, Franck

    Leads 2 awards · $585,276

    • 1R01AG031524-01Department: NIH department code

      A kinase pathway required for cortical neuron polarization
      $297,160

      award amount
    • 5R01NS047701-05Department: NIH department code

      Genetic Specification Of Thalamocortical Projections
      $288,116

      award amount

17. Liu, Rihe

    Leads 2 awards · $571,570

    • 1R21DA025702-01Department: NIH department code

      Identification of the Interactome of Methylated Histones from Human Proteome
      $292,890

      award amount
    • 5R01NS047650-05Department: NIH department code

      Identification of Caspase Substrates from Human Proteome
      $278,680

      award amount

18. Sondek, John E

    Leads 2 awards · $570,875

    • 2R01GM062299-05A1Department: NIH department code

      Functions and regulation of Dbl-family guanine nucleotide exchange factors
      $293,475

      award amount
    • 5R01GM081881-02Department: NIH department code

      GBeta5/RGS proteins and GPCR signaling
      $277,400

      award amount

19. Lee, Andrew L

    Leads 2 awards · $558,471

    • 5R01GM066009-05Department: NIH department code

      COUPLING NETWORKS AND SIDE-CHAIN DYNAMICS IN PROTEINS
      $313,125

      award amount
    • 1R01GM083059-01Department: NIH department code

      Intra- and Intermolecular Dynamics of Dihydrofolate Reductase
      $245,346

      award amount

20. Sleath, Betsy Lynn

    Leads 2 awards · $403,564

    • 5R01HL069837-04Department: NIH department code

      Children and Asthma: Communication and Outcomes
      $399,451

      award amount
    • 3R01HL069837-03S2Department: NIH department code

      Children and Asthma: Communication and Outcomes
      $4,113

      award amount

21. Smith, Philip C

    Leads 1 award · $380,917

    • 1S10RR024595-01Department: NIH department code

      Shared UPLC-MS/MS for Absolute Quantitative Proteomics
      $380,917

      award amount

22. Harden, T Kendall

    Leads 1 award · $368,358

    • 2R01GM057391-10Department: NIH department code

      Regulation of phospholipase C
      $368,358

      award amount

23. Brouwer, Kim L.r.

    Leads 1 award · $354,451

    • 5R01GM041935-17Department: NIH department code

      ALTERED HEPATIC DISPOSITION OF ANIONIC DRUGS-MECHANISMS
      $354,451

      award amount

24. Liu, Jian

    Leads 2 awards · $326,592

    • 5R01AI050050-07Department: NIH department code

      Structural Specificity of Heparan Sulfate for Herpes Infections
      $280,676

      award amount
    • 3R01AI050050-07S1Department: NIH department code

      Structural Specificity of Heparan Sulfate for Herpes Infections
      $45,916

      award amount

25. Singleton, Scott F

    Leads 1 award · $323,950

    • 2R56GM058114-09A1Department: NIH department code

      Understanding Homology in Genetic Recombination
      $323,950

      award amount

26. Kohn, Harold Lewis

    Leads 1 award · $317,521

    • 5R01NS054112-03Department: NIH department code

      Novel Methods to Identify Targets of the Neurological Agent (R)-Lacosamide
      $317,521

      award amount

27. Paine, Mary F

    Leads 1 award · $312,667

    • 5R01GM077482-02Department: NIH department code

      Mechanisms Underlying Drug-Diet Interactions
      $312,667

      award amount

28. Wiltshire, Tim

    Leads 1 award · $312,342

    • 7R01MH077251-02Department: NIH department code

      Organismal, Cellular, and Genetic Networks in Anxiety and Depression
      $312,342

      award amount

29. Cho, Moo J

    Leads 1 award · $301,516

    • 1R01CA126825-01A2Department: NIH department code

      Systemic Delivery of CpG Oligonucleotides
      $301,516

      award amount

30. Harden, T Kendall

    Leads 1 award · $296,974

    • 5R01GM038213-21Department: NIH department code

      P2Y-Purinergic Receptors
      $296,974

      award amount

31. Blancafort, Pilar

    Leads 1 award · $277,400

    • 5R01CA125273-02Department: NIH department code

      Re-activation of maspin tumor suppressor gene by designed transcription factors
      $277,400

      award amount

32. Lawrence, David S.

    Leads 1 award · $276,618

    • 5R01NS048406-05Department: NIH department code

      Intracellular Probes for Studying PKG Activity
      $276,618

      award amount

33. McLaughlin, James

    Leads 1 award · $271,331

    • 5R01DA017882-05Department: NIH department code

      Agonist-driven conformational changes in nAChRs
      $271,331

      award amount

34. Pollack, Gary M

    Leads 1 award · $191,484

    • 5R25GM074088-04Department: NIH department code

      SHORT COURSE: INTEGRATIVE AND ORGAN SYSTEMS PHARMACOLOGY
      $191,484

      award amount

35. Roth, Mary T

    Leads 1 award · $153,485

    • 5K23AG024229-03Department: NIH department code

      Improving the Quality of Medication Use in Older Adults
      $153,485

      award amount

36. Hawke, Roy L

    Leads 1 award · $147,500

    • 1R21AT003892-01A2Department: NIH department code

      CAM Herbal Cocktails for Boosting Antioxident Activity to Treat Liver Disease
      $147,500

      award amount

37. Petit, Chad

    Leads 1 award · $49,646

    • 5F32GM082006-02Department: NIH department code

      Structure and Dynamics of an Evolved 3C Protease
      $49,646

      award amount

38. Cline, Daniel J.

    Leads 1 award · $40,855

    • 5F32AI071486-03Department: NIH department code

      RecA Protein as Therapeutic Target Using Peptides & PNAs
      $40,855

      award amount

39. Trejo, Joann

    Leads 1 award · $32,833

    • 5R01HL073328-05Department: NIH department code

      Regulation of Protease-activated Receptor-1 Signaling
      $32,833

      award amount

40. Kimple, Adam J

    Leads 1 award · $32,066

    • 5F30MH074266-02Department: NIH department code

      Towards small molecule modulators of RGS proteins
      $32,066

      award amount

41. Coleman, Leon Garland

    Leads 1 award · $28,987

    • 1F30AA018051-01Department: NIH department code

      Alcohol and Development of the Prefrontal Cortex
      $28,987

      award amount

42. Hand, Randal A

    Leads 1 award · $28,776

    • 5F31MH078665-03Department: NIH department code

      Transcriptional regulation by Neurogenin2
      $28,776

      award amount

43. Welch, Christopher M

    Leads 1 award · $28,705

    • 1F30HL094020-01Department: NIH department code

      Leukocyte Transendothelial Migration: Coordination of Rho GTPase Signaling
      $28,705

      award amount

44. Ricks, Tiffany K

    Leads 1 award · $28,245

    • 5F31CA123700-03Department: NIH department code

      Minority Predoctoral Fellowship Program
      $28,245

      award amount

45. Watson, Venita Gresham

    Leads 1 award · $28,035

    • 5F31CA119938-03Department: NIH department code

      Paclitaxel Carrier from Protein Library
      $28,035

      award amount

46. Cole, Daud

    Leads 1 award · $27,481

    • 1F31GM086084-01Department: NIH department code

      The structure of telomerase RNA during catalysis
      $27,481

      award amount

47. Morieux, Pierre P.

    Leads 1 award · $27,199

    • 5F31NS060358-02Department: NIH department code

      Chemical Probes to Discover the Lacosamide Drug Targets: Synthesis and Evaluation
      $27,199

      award amount

48. Vitriol, Eric A

    Leads 1 award · $26,674

    • 1F31NS062487-01Department: NIH department code

      Spatiotemporal Dynamics of RhoA Activation in Growth Cone Motility
      $26,674

      award amount

49. Johnson, Jarrod Sean

    Leads 1 award · $26,052

    • 5F31NS060688-02Department: NIH department code

      Enhancing Gene Therapy by Designing Chimeric AAV Virions
      $26,052

      award amount

50. Nakamura, Kazuhiro

    Leads 1 award · $25,000

    • 1R03MH084830-01Department: NIH department code

      TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain Interaction
      $25,000

      award amount

51. Roadcap, David W

    Leads 1 award · $24,823

    • 5F32CA128297-02Department: NIH department code

      The control of metastasis by oncogene-induced actin regulatory proteins
      $24,823

      award amount