Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

56 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Crews, Fulton T

   Leads 6 awards · $3,469,698

   • 5P60AA011605-13Department: NIH department code

     Molecular and Cellular Pathogenesis in Alcoholism
     $1,807,807

     award amount
   • 1U24AA020024-01Department: NIH department code

     UNC-CH NADIA Administrative Core
     $442,735

     award amount
   • 1U24AA020022-01Department: NIH department code

     UNC-CH NADIA Scientific Core
     $436,228

     award amount
   • 1U01AA020023-01Department: NIH department code

     UNC-CH NADIA Underage Drinking and Adult Brain Morphology in Rats
     $371,333

     award amount
   • 5T32AA007573-13Department: NIH department code

     Molecular and Cellular Alcohol Research Training
     $270,995

     award amount
   • 1U54AA019767-01Department: NIH department code

     Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC
     $140,600

     award amount

2. Roth, Bryan L.

   Leads 4 awards · $2,704,841

   • 5U19MH082441-04Department: NIH department code

     Functional Selectivity: A Novel approach for CNS Drug Discovery
     $1,653,900

     award amount
   • 2R01MH061887-11Department: NIH department code

     Targeting and Trafficking of 5-HT2A Serotonin Receptors
     $367,120

     award amount
   • 2R01DA017204-06A1Department: NIH department code

     Diterpines as Selective Kappa Opioid Receptor Agonists
     $358,037

     award amount
   • 3U19MH082441-03S1Department: NIH department code

     Functional Selectivity: A Novel Approach for CNS Drug Discovery
     $325,784

     award amount

3. Samulski, Richard J

   Leads 2 awards · $1,767,105

   • 5U54AR056953-03Department: NIH department code

     Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center
     $1,404,947

     award amount
   • 5R01AI072176-03Department: NIH department code

     Rational and combinatorial engineering of AAV vectors
     $362,158

     award amount

4. Johnson, Gary L.

   Leads 4 awards · $1,097,235

   • 5R01GM030324-32Department: NIH department code

     Receptor Interaction with GTP-Regulatory Proteins
     $362,637

     award amount
   • 5R01DK037871-28Department: NIH department code

     Regulation of Sequential Protein Kinase Pathways
     $318,711

     award amount
   • 5R01GM068820-07Department: NIH department code

     Function of MEKK3 and its osmosensing scaffold protein
     $314,517

     award amount
   • 3R01DK037871-28S1Department: NIH department code

     Regulation of Sequential Protein Kinase Pathways
     $101,370

     award amount

5. Nicholas, Robert A

   Leads 3 awards · $1,062,841

   • 5R01HL071131-07Department: NIH department code

     Trafficking/signaling of P2Y receptors in polarized epithelial cells
     $364,498

     award amount
   • 2T32GM007040-36Department: NIH department code

     Predoctoral Training in Pharmacological Sciences
     $354,138

     award amount
   • 5R01AI036901-15Department: NIH department code

     Mechanisms of antibiotic action in Neisseria gonorrhoeae.
     $344,205

     award amount

6. Liu, Jian

   Leads 4 awards · $954,331

   • 5R01HL094463-02Department: NIH department code

     In vitro synthesis of recombinant heparan sulfate
     $423,870

     award amount
   • 5R01AI050050-09Department: NIH department code

     Structural Specificity of Heparan Sulfate for Herpes Infections
     $325,744

     award amount
   • 5R21AI074775-02Department: NIH department code

     Glycomics of Heparan Sulfate in Bacterial Pathogenesis
     $197,258

     award amount
   • 3R01AI050050-09S1Department: NIH department code

     Structural Specificity of Heparan Sulfate for Herpes Infections
     $7,459

     award amount

7. Lee, Kuo-Hsiung

   Leads 2 awards · $906,711

   • 5R01AI077417-03Department: NIH department code

     Modified Triterpines as Potent HIV Fusion Inhibitors
     $456,822

     award amount
   • 5R01AI033066-19Department: NIH department code

     PLANT ANTI-HIV AGENTS
     $449,889

     award amount

8. Der, Channing J.

   Leads 4 awards · $892,201

   • 5R01CA129610-03Department: NIH department code

     Mechanism and role of DLC-1 tumor suppressor loss in lung cancer
     $305,763

     award amount
   • 5R01CA127152-04Department: NIH department code

     Role of RGS proteins in Ras- and B-Raf--mediated transformation
     $221,178

     award amount
   • 5T32CA071341-15Department: NIH department code

     Cancer Cell Biology Training Program
     $188,294

     award amount
   • 2R01CA042978-24A1Department: NIH department code

     Biological Activity of Ras Oncogenes
     $176,966

     award amount

9. Huang, Leaf

   Leads 3 awards · $849,142

   • 5R01CA129835-03Department: NIH department code

     LPD Nanoparticles in Anti-Cancer Therapy
     $301,885

     award amount
   • 5R01CA129421-03Department: NIH department code

     Interaction of cationic lipids with dendritic cells
     $301,284

     award amount
   • 1R01CA149363-01Department: NIH department code

     Novel nanoparticles for siRNA delivery
     $245,973

     award amount

10. Chou, Kyson Xiaohuai

    Leads 1 award · $810,359

    • 5R01EY019555-02Department: NIH department code

      Differential regulation of multiple transgenes for treatment of eye disease
      $810,359

      award amount

11. Hahn, Klaus M.

    Leads 3 awards · $702,656

    • 5R01GM057464-11Department: NIH department code

      Dye-Based biosensors: simultaneous imaging of multiple protein activities
      $366,300

      award amount
    • 5R01GM082288-12Department: NIH department code

      Versatile scaffolds to visualize endogenous protein activation in living cells
      $280,410

      award amount
    • 3R01GM057464-11S1Department: NIH department code

      Dye-Based biosensors: simultaneous imaging of multiple protein activities
      $55,946

      award amount

12. McCarthy, Ken Douglas

    Leads 2 awards · $692,237

    • 5R01NS020212-25Department: NIH department code

      Neuronal-Astrocytic Communication In Vivo
      $377,470

      award amount
    • 5R01NS058904-03Department: NIH department code

      Role of Spinal Cord Lamina II Astrocytes in Neurophysiology and Chronic Pain
      $314,767

      award amount

13. Li, Chengwen

    Leads 3 awards · $678,173

    • 1R01AI080726-01A2Department: NIH department code

      CTL response to AAV Vector
      $366,784

      award amount
    • 5R01DK084033-02Department: NIH department code

      AAV Gene Therapy for AAT deficiency
      $295,993

      award amount
    • 3R01AI080726-01A2S1Department: NIH department code

      CTL response to AAV Vector
      $15,396

      award amount

14. Lee, Andrew L

    Leads 4 awards · $637,071

    • 5R01GM066009-07Department: NIH department code

      Dynamic Networks and Mechanisms of Allosteric Communication in Proteins
      $332,175

      award amount
    • 5R01GM083059-03Department: NIH department code

      Intra- and Intermolecular Dynamics of Dihydrofolate Reductase
      $271,694

      award amount
    • 3R01GM066009-07S1Department: NIH department code

      Dynamic Networks and Mechanisms of Allosteric Communication in Proteins
      $21,362

      award amount
    • 3R01GM083059-03S1Department: NIH department code

      Intra- and Intermolecular Dynamics of Dihydrofolate Reductase
      $11,840

      award amount

15. Kash, Thomas L.

    Leads 2 awards · $569,793

    • 1R01AA019454-01A1Department: NIH department code

      The Role of Serotonin in Alcohol-Withdrawal Induced Anxiety
      $323,283

      award amount
    • 5R00AA017668-03Department: NIH department code

      Role of the Dopaminergic PAG projection to BNST in alcohol abuse
      $246,510

      award amount

16. Sondek, John E

    Leads 2 awards · $566,836

    • 5R01GM062299-07Department: NIH department code

      Functions and regulation of Dbl-family guanine nucleotide exchange factors
      $292,210

      award amount
    • 5R01GM081881-04Department: NIH department code

      GBeta5/RGS proteins and GPCR signaling
      $274,626

      award amount

17. Polleux, Franck

    Leads 2 awards · $506,051

    • 5R01AG031524-03Department: NIH department code

      A kinase pathway required for cortical neuron polarization
      $294,188

      award amount
    • 1R01NS067557-01A1Department: NIH department code

      Functions of membrane deforming-proteins during neuronal development
      $211,863

      award amount

18. Frye, Stephen Vernon

    Leads 1 award · $441,607

    • 5RC1GM090732-02Department: NIH department code

      Discovery of Small Molecule MBT Domain Antagonists
      $441,607

      award amount

19. Lawrence, David S.

    Leads 1 award · $427,079

    • 5R01CA140173-02Department: NIH department code

      Signaling Network Dynamics in Metastatic Prostate Cancer
      $427,079

      award amount

20. Snider, William D

    Leads 1 award · $408,720

    • 5T32NS007431-12Department: NIH department code

      Research Training in the Neurosciences
      $408,720

      award amount

21. Harden, T Kendall

    Leads 1 award · $389,017

    • 5R01GM057391-12Department: NIH department code

      Regulation of phospholipase C
      $389,017

      award amount

22. Brouwer, Kim L.r.

    Leads 1 award · $364,804

    • 2R01GM041935-18A1Department: NIH department code

      ALTERED HEPATIC DISPOSITION OF ANIONIC DRUGS-MECHANISMS
      $364,804

      award amount

23. Thakker, Dhiren R

    Leads 1 award · $355,204

    • 1R01DK088097-01A1Department: NIH department code

      Role of a Novel Absorption Mechanism in Metformin Disposition and Pharmacology
      $355,204

      award amount

24. Wang, Zhuo Michael

    Leads 1 award · $334,285

    • 1R01GM089994-01A1Department: NIH department code

      Human Cytochrome P450 4F Enzymes and Drug Interactions
      $334,285

      award amount

25. Xiao, Xiao

    Leads 1 award · $329,670

    • 5R01AR056394-02Department: NIH department code

      Myostatin Inhibition in DMD Dogs by Gene Transfer
      $329,670

      award amount

26. Singleton, Scott F

    Leads 1 award · $316,383

    • 5R01GM058114-10Department: NIH department code

      Understanding Homology in Genetic Recombination
      $316,383

      award amount

27. Wiltshire, Tim

    Leads 1 award · $313,325

    • 5R01MH077251-04Department: NIH department code

      Organismal, Cellular, and Genetic Networks in Anxiety and Depression
      $313,325

      award amount

28. Elston, Timothy C

    Leads 1 award · $312,067

    • 2R01GM079271-05Department: NIH department code

      Spatiotemporal modeling of signal transduction in yeast
      $312,067

      award amount

29. Paine, Mary F

    Leads 1 award · $311,357

    • 5R01GM077482-04Department: NIH department code

      Mechanisms Underlying Drug-Diet Interactions
      $311,357

      award amount

30. Lee, Craig R

    Leads 1 award · $308,668

    • 5R01GM088199-02Department: NIH department code

      Cytochrome P450 Derived Eicosanoids and Inflammation
      $308,668

      award amount

31. Cho, Moo J

    Leads 1 award · $302,226

    • 5R01CA126825-03Department: NIH department code

      Systemic Delivery of CpG Oligonucleotides
      $302,226

      award amount

32. Siderovski, David P.

    Leads 3 awards · $299,346

    • 5R01GM082892-03Department: NIH department code

      Structural Determinants of Heterotrimeric G-protein Nucleotide Cycling
      $222,710

      award amount
    • 3R01GM082892-03S1Department: NIH department code

      Structural Determinants of Heterotrimeric G-protein Nucleotide Cycling
      $39,657

      award amount
    • 1R03DA030555-01Department: NIH department code

      Enzymatic Screen for RGS Protein Modulators
      $36,979

      award amount

33. Tropsha, Alexander

    Leads 1 award · $282,516

    • 5R01GM066940-07Department: NIH department code

      Predictive QSAR Modeling
      $282,516

      award amount

34. Blancafort, Pilar

    Leads 1 award · $277,400

    • 5R01CA125273-04Department: NIH department code

      Re-activation of maspin tumor suppressor gene by designed transcription factors
      $277,400

      award amount

35. Innocenti, Federico

    Leads 2 awards · $277,069

    • 7R21DK081157-03Department: NIH department code

      Genome-wide SNP genotyping and expression analysis in human livers
      $169,065

      award amount
    • 7K07CA140390-03Department: NIH department code

      Genome-Wide molecular epidemiology of treatment outcome and cancer risk
      $108,004

      award amount

36. Reiner, David

    Leads 1 award · $276,111

    • 1R01GM085309-01A2Department: NIH department code

      The Ral small GTPase in C. elegans development
      $276,111

      award amount

37. Harden, T Kendall

    Leads 1 award · $256,410

    • 5R01GM038213-23Department: NIH department code

      P2Y-Purinergic Receptors
      $256,410

      award amount

38. Hawke, Roy L

    Leads 1 award · $237,949

    • 5R21AT003892-03Department: NIH department code

      CAM Herbal Cocktails for Boosting Antioxident Activity to Treat Liver Disease
      $237,949

      award amount

39. Whitehurst, Angelique Wright

    Leads 1 award · $207,151

    • 5R00CA128926-03Department: NIH department code

      Harnessing Functional Genomics to Reveal Cancer Specific Determinants of Mitosis
      $207,151

      award amount

40. Roth, Mary T

    Leads 1 award · $152,808

    • 5K23AG024229-05Department: NIH department code

      Improving the Quality of Medication Use in Older Adults
      $152,808

      award amount

41. Zhang, Qisheng

    Leads 1 award · $73,351

    • 1R21NS073041-01Department: NIH department code

      High Throughput Assay Development for ARFGAP Modulators
      $73,351

      award amount

42. Juliano, Rudolph

    Leads 1 award · $56,453

    • 3P01GM059299-10S2Department: NIH department code

      The Pharmacodynamics of Genes and Oligonucleotides
      $56,453

      award amount

43. Richards, Justin James

    Leads 1 award · $45,590

    • 1F32AI089050-01Department: NIH department code

      Functionally Selective RecA Inhibitors to Probe Bacterial Genetic Recombination
      $45,590

      award amount

44. Janzen, William Perry

    Leads 1 award · $37,000

    • 1R03DA030553-01Department: NIH department code

      High-Throughput Screening for the Discovery of Novel Scaffolds that Anatagonize M
      $37,000

      award amount

45. Coleman, Leon Garland

    Leads 1 award · $33,114

    • 5F30AA018051-03Department: NIH department code

      Alcohol and Development of the Prefrontal Cortex
      $33,114

      award amount

46. Kimple, Adam J

    Leads 1 award · $32,474

    • 5F30MH074266-04Department: NIH department code

      Towards small molecule modulators of RGS proteins
      $32,474

      award amount

47. Peterson, Sherket Breshon

    Leads 1 award · $32,247

    • 1F31GM090647-01Department: NIH department code

      Enzyme-based approach to probe the specificity of heparanase and its inhibitor
      $32,247

      award amount

48. Farrell, Martilias Stephen

    Leads 1 award · $29,932

    • 1F31MH091921-01Department: NIH department code

      Cell Type Specific Control of Neuronal Signaling
      $29,932

      award amount

49. Goldsmith, Jason R.

    Leads 1 award · $29,677

    • 1F30DK085906-01A1Department: NIH department code

      The role of the mu-Opioid Receptor in Inflammatory Bowel Disease Pathology and Th
      $29,677

      award amount

50. Morgan-Smith, Meghan Lynn

    Leads 1 award · $29,671

    • 5F31NS067838-02Department: NIH department code

      Exploring the Role of TAK1 in Neuronal Polarization
      $29,671

      award amount

51. Welch, Christopher M

    Leads 1 award · $29,602

    • 5F30HL094020-03Department: NIH department code

      Leukocyte Transendothelial Migration: Coordination of Rho GTPase Signaling
      $29,602

      award amount

52. Rogan, Sarah Claire

    Leads 1 award · $28,063

    • 5F30MH087074-02Department: NIH department code

      In Vivo Neuronal Modulation via Engineered G Protein-Coupled Receptors
      $28,063

      award amount

53. He, Bo

    Leads 1 award · $27,928

    • 1F31NS070540-01Department: NIH department code

      Gene delivery of MG53 for muscle membrane repair and functional improvement in a
      $27,928

      award amount

54. Cole, Daud

    Leads 1 award · $27,889

    • 5F31GM086084-03Department: NIH department code

      The structure of telomerase RNA during catalysis
      $27,889

      award amount

55. Wu, Yi

    Leads 1 award · $17,760

    • 1R21NS071216-01Department: NIH department code

      Engineering a new class of optogenetic tools targeting small GTPases and kinases
      $17,760

      award amount

56. Watson, Venita Gresham

    Leads 1 award · $11,986

    • 5F31CA119938-05Department: NIH department code

      Paclitaxel Carrier from Protein Library
      $11,986

      award amount