Pharmacology at University of North Carolina at Chapel Hill

Leads a grant in this department

64 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Crews, Fulton T

   Leads 7 awards · $3,470,179

   • 5P60AA011605-14Department: NIH department code

     Molecular and Cellular Pathogenesis in Alcoholism
     $1,742,366

     award amount
   • 5U24AA020022-02Department: NIH department code

     UNC-CH NADIA Scientific Core
     $443,533

     award amount
   • 5U24AA020024-02Department: NIH department code

     UNC-CH NADIA Administrative Core
     $435,682

     award amount
   • 5U01AA020023-02Department: NIH department code

     UNC-CH NADIA Underage Drinking and Adult Brain Morphology in Rats
     $365,522

     award amount
   • 5T32AA007573-14Department: NIH department code

     Molecular and Cellular Alcohol Research Training
     $268,882

     award amount
   • 5U54AA019767-02Department: NIH department code

     Mechanisms of Alcohol Pathology: A Collaborative Partnership Between NCCU & UNC
     $139,194

     award amount
   • 3U01AA020023-02S1Department: NIH department code

     UNC-CH NADIA Underage Drinking and Adult Brain Morphology in Rats
     $75,000

     award amount

2. Roth, Bryan L.

   Leads 3 awards · $2,310,104

   • 5U19MH082441-05Department: NIH department code

     Functional Selectivity: A Novel approach for CNS Drug Discovery
     $1,623,361

     award amount
   • 5R01MH061887-12Department: NIH department code

     Targeting and Trafficking of 5-HT2A Serotonin Receptors
     $363,449

     award amount
   • 5R01DA017204-07Department: NIH department code

     Diterpines as Selective Kappa Opioid Receptor Agonists
     $323,294

     award amount

3. Samulski, Richard J

   Leads 2 awards · $1,757,006

   • 5U54AR056953-04Department: NIH department code

     Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center
     $1,398,548

     award amount
   • 5R01AI072176-04Department: NIH department code

     Rational and combinatorial engineering of AAV vectors
     $358,458

     award amount

4. Der, Channing J.

   Leads 4 awards · $1,061,164

   • 5R01CA042978-25Department: NIH department code

     Biological Activity of Ras Oncogenes
     $356,891

     award amount
   • 5R01CA129610-04Department: NIH department code

     Mechanism and role of DLC-1 tumor suppressor loss in lung cancer
     $296,590

     award amount
   • 5R01CA127152-05Department: NIH department code

     Role of RGS proteins in Ras- and B-Raf--mediated transformation
     $214,543

     award amount
   • 1R21CA161494-01Department: NIH department code

     Genetic dissection and inhibitor targeting of Rac signaling in pancreatic cancer.
     $193,140

     award amount

5. Johnson, Gary L.

   Leads 3 awards · $985,907

   • 5R01GM030324-33Department: NIH department code

     Receptor Interaction with GTP-Regulatory Proteins
     $359,011

     award amount
   • 5R01DK037871-29Department: NIH department code

     Regulation of Sequential Protein Kinase Pathways
     $315,524

     award amount
   • 5R01GM068820-08Department: NIH department code

     Function of MEKK3 and its osmosensing scaffold protein
     $311,372

     award amount

6. Lee, Kuo-Hsiung

   Leads 2 awards · $900,361

   • 5R01AI077417-04Department: NIH department code

     Modified Triterpines as Potent HIV Fusion Inhibitors
     $451,483

     award amount
   • 5R01AI033066-20Department: NIH department code

     PLANT ANTI-HIV AGENTS
     $448,878

     award amount

7. McCarthy, Ken Douglas

   Leads 2 awards · $836,522

   • 1R01EY021190-01Department: NIH department code

     ASTROCYTE-NEURONAL INTERACTIONS IN THE VISUAL CORTEX
     $459,039

     award amount
   • 5R01NS020212-26Department: NIH department code

     Neuronal-Astrocytic Communication In Vivo
     $377,483

     award amount

8. Huang, Leaf

   Leads 3 awards · $823,467

   • 5R01CA129835-04Department: NIH department code

     LPD Nanoparticles in Anti-Cancer Therapy
     $292,676

     award amount
   • 5R01CA129421-04Department: NIH department code

     Interaction of cationic lipids with dendritic cells
     $292,197

     award amount
   • 5R01CA149363-02Department: NIH department code

     Novel nanoparticles for siRNA delivery
     $238,594

     award amount

9. Kashuba, Angela D

   Leads 1 award · $731,273

   • 1U01AI095031-01Department: NIH department code

     Preventing HIV Infection in Women: Targeting Antiretrovirals to Mucosal Tissues
     $731,273

     award amount

10. Nicholas, Robert A

    Leads 2 awards · $722,716

    • 5R01HL071131-08Department: NIH department code

      Trafficking/signaling of P2Y receptors in polarized epithelial cells
      $364,498

      award amount
    • 5T32GM007040-37Department: NIH department code

      Predoctoral Training in Pharmacological Sciences
      $358,218

      award amount

11. Lawrence, David S.

    Leads 2 awards · $718,104

    • 5R01CA140173-03Department: NIH department code

      Signaling Network Dynamics in Metastatic Prostate Cancer
      $411,004

      award amount
    • 1R01CA159189-01Department: NIH department code

      Spatiotemporal Control of Tumor Cell Signaling
      $307,100

      award amount

12. Xiao, Xiao

    Leads 2 awards · $686,483

    • 1R01DK090380-01A1Department: NIH department code

      Muscle as a Platform for Type 2 Diabetes Treatment by Gene Delivery
      $370,000

      award amount
    • 5R01AR056394-03Department: NIH department code

      Myostatin Inhibition in DMD Dogs by Gene Transfer
      $316,483

      award amount

13. Lee, Andrew L

    Leads 2 awards · $608,577

    • 5R01GM066009-08Department: NIH department code

      Dynamic Networks and Mechanisms of Allosteric Communication in Proteins
      $324,302

      award amount
    • 5R01GM083059-04Department: NIH department code

      Intra- and Intermolecular Dynamics of Dihydrofolate Reductase
      $284,275

      award amount

14. Kash, Thomas L.

    Leads 2 awards · $574,149

    • 5R01AA019454-02Department: NIH department code

      The Role of Serotonin in Alcohol-Withdrawal Induced Anxiety
      $337,204

      award amount
    • 5R00AA017668-04Department: NIH department code

      Role of the Dopaminergic PAG projection to BNST in alcohol abuse
      $236,945

      award amount

15. Whitehurst, Angelique Wright

    Leads 2 awards · $546,409

    • 1R01CA154699-01Department: NIH department code

      Mechanistic Elaboration of Fragility in the Cancer Cell Mitotic Spindle
      $304,879

      award amount
    • 5R00CA128926-04Department: NIH department code

      Harnessing Functional Genomics to Reveal Cancer Specific Determinants of Mitosis
      $241,530

      award amount

16. Brouwer, Kim L.r.

    Leads 2 awards · $531,625

    • 5R01GM041935-19Department: NIH department code

      ALTERED HEPATIC DISPOSITION OF ANIONIC DRUGS-MECHANISMS
      $361,002

      award amount
    • 3R01GM041935-19S1Department: NIH department code

      ALTERED HEPATIC DISPOSITION OF ANIONIC DRUGS-MECHANISMS
      $170,623

      award amount

17. Wang, Zefeng

    Leads 2 awards · $433,184

    • 1R01CA158283-01Department: NIH department code

      Modulation of VEGF-A alternative splicing as new anti-angiogenic therapeutics
      $270,572

      award amount
    • 1R21AR061640-01Department: NIH department code

      Artificial site-specific RNA endonuclease as new Myotonic Dystrophy therapeutics
      $162,612

      award amount

18. Snider, William D

    Leads 1 award · $413,256

    • 5T32NS007431-13Department: NIH department code

      Research Training in the Neurosciences
      $413,256

      award amount

19. Liu, Jian

    Leads 1 award · $407,650

    • 5R01HL094463-03Department: NIH department code

      In vitro synthesis of recombinant heparan sulfate
      $407,650

      award amount

20. Harden, T Kendall

    Leads 1 award · $385,053

    • 5R01GM057391-13Department: NIH department code

      Regulation of phospholipase C
      $385,053

      award amount

21. Lai, Samuel

    Leads 2 awards · $366,946

    • 1R21AI090507-01A1Department: NIH department code

      Diffusion of viruses across human airway mucus and trapping by antibodies
      $183,473

      award amount
    • 1R21AI093242-01Department: NIH department code

      Trapping HIV in mucus with IgG antibodies
      $183,473

      award amount

22. Li, Chengwen

    Leads 1 award · $363,116

    • 5R01AI080726-02Department: NIH department code

      CTL response to AAV Vector
      $363,116

      award amount

23. Hahn, Klaus M.

    Leads 1 award · $362,637

    • 5R01GM057464-12Department: NIH department code

      Dye-Based biosensors: simultaneous imaging of multiple protein activities
      $362,637

      award amount

24. Paine, Mary F

    Leads 1 award · $347,636

    • 2R01GM077482-05Department: NIH department code

      Mechanisms Underlying Drug-Diet Interactions
      $347,636

      award amount

25. Lee, Craig R

    Leads 2 awards · $331,331

    • 5R01GM088199-03Department: NIH department code

      Cytochrome P450 Derived Eicosanoids and Inflammation
      $302,861

      award amount
    • 3R01GM088199-03S1Department: NIH department code

      Cytochrome P450 Derived Eicosanoids and Inflammation
      $28,470

      award amount

26. Thakker, Dhiren R

    Leads 1 award · $314,072

    • 5R01DK088097-02Department: NIH department code

      Role of a Novel Absorption Mechanism in Metformin Disposition and Pharmacology
      $314,072

      award amount

27. Singleton, Scott F

    Leads 1 award · $313,042

    • 5R01GM058114-11Department: NIH department code

      Understanding Homology in Genetic Recombination
      $313,042

      award amount

28. Wiltshire, Tim

    Leads 1 award · $310,157

    • 5R01MH077251-05Department: NIH department code

      Organismal, Cellular, and Genetic Networks in Anxiety and Depression
      $310,157

      award amount

29. Liu, Feng

    Leads 1 award · $307,100

    • 1R01CA149387-01A1Department: NIH department code

      Nanocrystals for the Treatment of Multidrug Resistance in Cancer
      $307,100

      award amount

30. Zhang, Qisheng

    Leads 2 awards · $306,483

    • 1R01GM086558-01A1Department: NIH department code

      Developing Small Molecule ARFGAP Regulators to Dissect Cell Signaling
      $269,483

      award amount
    • 3R21NS073041-01S1Department: NIH department code

      High Throughput Assay Development for ARFGAP Modulators
      $37,000

      award amount

31. Elston, Timothy C

    Leads 1 award · $301,247

    • 5R01GM079271-06Department: NIH department code

      Spatiotemporal modeling of signal transduction in yeast
      $301,247

      award amount

32. Cho, Moo J

    Leads 1 award · $293,017

    • 5R01CA126825-04Department: NIH department code

      Systemic Delivery of CpG Oligonucleotides
      $293,017

      award amount

33. Sondek, John E

    Leads 1 award · $289,264

    • 5R01GM062299-08Department: NIH department code

      Functions and regulation of Dbl-family guanine nucleotide exchange factors
      $289,264

      award amount

34. Reiner, David

    Leads 1 award · $284,470

    • 5R01GM085309-02Department: NIH department code

      The Ral small GTPase in C. elegans development
      $284,470

      award amount

35. Tropsha, Alexander

    Leads 1 award · $284,418

    • 5R01GM066940-08Department: NIH department code

      Predictive QSAR Modeling
      $284,418

      award amount

36. Sondek, John E

    Leads 1 award · $281,200

    • 1R01GM098894-01Department: NIH department code

      High-throughput screens to identify modulators of phospholipase C isozymes
      $281,200

      award amount

37. Graves, Lee M

    Leads 1 award · $269,078

    • 5R01CA125273-05Department: NIH department code

      Re-activation of maspin tumor suppressor gene by designed transcription factors
      $269,078

      award amount

38. Yue, Wei

    Leads 1 award · $268,488

    • 1R01GM094268-01A1Department: NIH department code

      Function and regulation of OATP1B1 and OATP1B3
      $268,488

      award amount

39. Siderovski, David P.

    Leads 2 awards · $256,373

    • 5R01GM082892-04Department: NIH department code

      Structural Determinants of Heterotrimeric G-protein Nucleotide Cycling
      $220,483

      award amount
    • 5R03DA030555-02Department: NIH department code

      Enzymatic Screen for RGS Protein Modulators
      $35,890

      award amount

40. Harden, T Kendall

    Leads 1 award · $253,846

    • 5R01GM038213-24Department: NIH department code

      P2Y-Purinergic Receptors
      $253,846

      award amount

41. Liu, Rihe

    Leads 1 award · $219,402

    • 1R21AI092228-01Department: NIH department code

      Novel Anti-allergic Single-domain Antibody Against IgE
      $219,402

      award amount

42. Benjamin, Daniel K.

    Leads 1 award · $216,811

    • 1T32GM086330-01A1Department: NIH department code

      UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program
      $216,811

      award amount

43. Innocenti, Federico

    Leads 1 award · $131,139

    • 5K07CA140390-04Department: NIH department code

      Genome-Wide molecular epidemiology of treatment outcome and cancer risk
      $131,139

      award amount

44. Dumond, Julie Brumer

    Leads 1 award · $108,119

    • 1K23AI093156-01A1Department: NIH department code

      Optimizing Antiretroviral Use in Aging: Pharmacokinetics, Response, and Toxicity
      $108,119

      award amount

45. Wang, Zhuo Michael

    Leads 1 award · $88,219

    • 5R01GM089994-02Department: NIH department code

      Human Cytochrome P450 4F Enzymes and Drug Interactions
      $88,219

      award amount

46. Oestreich, Emily Anne

    Leads 1 award · $55,734

    • 5F32AR057644-02Department: NIH department code

      RGS12 as a MAPK Scaffold in Muscle Development and Disease
      $55,734

      award amount

47. Cohen, Staci P

    Leads 1 award · $48,398

    • 1F32DC011670-01Department: NIH department code

      The Role of RGS Proteins in the Regulation of Taste Transduction
      $48,398

      award amount

48. Cook, Danielle Ryan

    Leads 1 award · $40,397

    • 1F31CA159821-01Department: NIH department code

      Elucidating the Molecular Mechanisms of Ect2 in cytokinesis and oncogenesis
      $40,397

      award amount

49. Richards, Justin James

    Leads 1 award · $38,261

    • 5F32AI089050-02Department: NIH department code

      Functionally Selective RecA Inhibitors to Probe Bacterial Genetic Recombination
      $38,261

      award amount

50. Janzen, William Perry

    Leads 1 award · $35,890

    • 5R03DA030553-02Department: NIH department code

      High-Throughput Screening for the Discovery of Novel Scaffolds that Anatagonize M
      $35,890

      award amount

51. Bosch, Dustin E

    Leads 1 award · $34,337

    • 1F30DK091978-01Department: NIH department code

      Elucidating a G-protein signaling pathway in E. histolytica amoebic colitis
      $34,337

      award amount

52. Rogan, Sarah Claire

    Leads 1 award · $33,535

    • 5F30MH087074-03Department: NIH department code

      In Vivo Neuronal Modulation via Engineered G Protein-Coupled Receptors
      $33,535

      award amount

53. Gillette, Chris

    Leads 1 award · $33,129

    • 1R36HS020534-01Department: NIH department code

      The Effect of Risk and Side Effect Communication on Asthma Medication Adherence
      $33,129

      award amount

54. Welch, Christopher M

    Leads 1 award · $33,078

    • 5F30HL094020-04Department: NIH department code

      Leukocyte Transendothelial Migration: Coordination of Rho GTPase Signaling
      $33,078

      award amount

55. Kimple, Adam J

    Leads 1 award · $32,894

    • 5F30MH074266-05Department: NIH department code

      Towards small molecule modulators of RGS proteins
      $32,894

      award amount

56. Peterson, Sherket Breshon

    Leads 1 award · $32,667

    • 5F31GM090647-02Department: NIH department code

      Enzyme-based approach to probe the specificity of heparanase and its inhibitor
      $32,667

      award amount

57. Dibble, Christopher F

    Leads 1 award · $30,866

    • 1F30HL108598-01Department: NIH department code

      Endothelial Progenitor-derived Endothelial Cells as a Model for Familial CCM
      $30,866

      award amount

58. Farrell, Martilias Stephen

    Leads 1 award · $30,488

    • 5F31MH091921-02Department: NIH department code

      Cell Type Specific Control of Neuronal Signaling
      $30,488

      award amount

59. Phillips, Ryan Matthew

    Leads 1 award · $30,224

    • 1F30ES019829-01Department: NIH department code

      Single Cell Analysis of EGFR Activity in Human Airway Cells Exposed to Pollutants
      $30,224

      award amount

60. Morgan-Smith, Meghan Lynn

    Leads 1 award · $30,091

    • 5F31NS067838-03Department: NIH department code

      Exploring the Role of TAK1 in Neuronal Polarization
      $30,091

      award amount

61. Chappell, Elizabeth Pempe

    Leads 1 award · $28,951

    • 1F31AG040927-01Department: NIH department code

      Contribution of Structural Motifs to Heparin Clearance
      $28,951

      award amount

62. Cole, Daud

    Leads 1 award · $28,309

    • 5F31GM086084-04Department: NIH department code

      The structure of telomerase RNA during catalysis
      $28,309

      award amount

63. Coleman, Leon Garland

    Leads 1 award · $27,685

    • 5F30AA018051-04Department: NIH department code

      Alcohol and Development of the Prefrontal Cortex
      $27,685

      award amount

64. He, Bo

    Leads 1 award · $19,871

    • 5F31NS070540-02Department: NIH department code

      Gene delivery of MG53 for muscle membrane repair and functional improvement in a
      $19,871

      award amount