ConductVision Morphology

Make Morphology Data Speak

Interactive 3D exploration of traced neurons. Compare populations, overlay Sholl analysis, and export publication-ready figures — without ever leaving the workspace.

Live Sholl overlayPopulation cohort overlaySWC + CSV export

See the Workspace →

One Workspace. Every Comparison.

Load traced neurons, group them by genotype or condition, and explore structural differences without round-tripping through ImageJ and Excel.

ConductVision · Morphology Explorer · cohort-2026-04.cve

Built for Structural Comparison

Every interaction is geared toward the question that matters: does the morphology actually differ between groups?

Live

Interactive 3D Sholl

Rotate, zoom, and section any traced neuron in real time. Sholl intersections recompute as you change shell radius. Toggle dendrite vs axon segments independently.

Color-code

Segment Overlays

Color by branch order, distance from soma, or local diameter. Primary, secondary, and tertiary dendrites resolve at a glance — no manual color picking, no plugin install.

Cohort overlay

Population Comparison

Drop multiple SWC files into a group (WT, KO, drug, vehicle). Compute mean Sholl curves with confidence bands and per-cell scatter. Cohort statistics surface phenotypes summary stats hide.

Pub-ready

CSV / SWC Export

Per-cell metrics (length, branches, complexity, fractal dim) export as CSV with cohort labels intact. Traced neurons round-trip through standard SWC, ASC, and OME-TIFF.

Workflows Already Loaded

Three of the most common comparisons, ready to drop your data into.

Genotype

WT vs KO Morphology

Compare dendritic complexity between genotypes. Sholl curves with cohort statistics surface phenotypes that average summary numbers miss.

Δ peak intersections: −34% (p = 0.0021)

Longitudinal

Plasticity Over Time

Track changes in branching, length, and spine density across time points. Per-cell or population view; alignment by soma landmark or chronological age.

Length growth: +124 µm/wk (control), +52 µm/wk (deprived)

Pharmacology

Drug-Effect Screen

Compare morphology across compound conditions. Cohort overlays with vehicle baseline highlight dose-dependent structural responses without leaving the workspace.

Dose response: r = 0.91 (branch count vs log[dose])

Standing on Standard Methods

Morphology Explorer implements the field’s shared vocabulary — published, validated, and unchanged since the soma-centered ring first appeared in 1953.

1953

Sholl, D. A. — “Dendritic organization in the neurons of the visual and motor cortices of the cat.” Established the concentric-shell intersection counting method that anchors every modern dendritic complexity analysis.

Journal of Anatomy · 87(4) · pp.387-406

2014

Cuntz et al. — “One rule to grow them all: a general theory of neuronal branching and its practical application.” Population-level scaling laws for branching geometry; underpins cohort-overlay statistics.

PLOS Computational Biology · 10(8) · e1003755

2020

Arshadi, Günther, Eddison et al. — “SNT: a unifying toolbox for quantification of neuronal anatomy.” Standardized SWC handling and morphology metrics referenced by Morphology Explorer’s export schema.

Nature Methods · 18 · pp.374-377

Stop Pasting Sholl Plots Into PowerPoint

Schedule a 30-minute walkthrough on your own traced data — bring an SWC, leave with a comparison-ready figure.

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