
Automatic Continuous Sectioning Microtome RD-495
Fully automatic continuous sectioning microtome with motorized operation and advanced digital controls

Louise Corscadden, PhD
Director of Science · ConductScience
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The RD-495 is a fully automatic microtome system designed for high-volume, specialized research applications. Featuring complete motorized operation for both cutting and specimen advancement, continuous sectioning capability, and a full digital touchscreen interface with pedal control, the RD-495 delivers precision and efficiency for demanding laboratory workflows.
Key Features:
- Fully motorized drive system (cut & advance)
- Section thickness range: 0.25 – 100 µm
- Trimming thickness range: 1 – 600 µm
- Automated specimen retraction
- Single, Continuous, and Step cutting modes
- Full digital touchscreen interface with pedal control
- Ideal for high-volume, specialized research
Microtome Series Comparison:
| Feature | RD-315 | RD-465 | RD-475 | RD-495 |
|---|---|---|---|---|
| Drive System | Handwheel (Manual) | Motorized advance, manual cut | Motorized advance, manual cut | Fully motorized (cut & advance) |
| Typical Section Thickness Range | 0 – 60 µm | 0.25 – 100 µm | 0.25 – 100 µm | 0.25 – 100 µm |
| Typical Trimming Thickness Range | 10 – 60 µm | 1 – 600 µm | 1 – 600 µm | 1 – 600 µm |
| Specimen Retraction | Mechanical (if equipped) | Automated | Automated | Automated |
| Cutting Modes | Manual only | Manual cut | Manual cut | Single, Continuous, Step |
| Control Panel | None / Basic analog | Digital display/keypad | Digital touchscreen / keypad | Full digital touchscreen/pedal |
| Best Used For | Basic histology, low volume | Medium volume, routine pathology | Medium/High volume, precision | High volume, specialized research |
| Price | $5,490 | $7,090 | $8,190 | $9,390 |
Sample Orientation
- RD-315: XY ±8°, 360° rotatable
- RD-475: 360° rotatable
- RD-495: XY ±8°
Model
- Standard - RD-315
- Intermediate - RD-465
- Professional - RD-475
- Advanced - RD-495
Horizontal Specimen Stroke
- RD-315: 0–28 mm
- RD-475: 28 mm ±1 mm
- RD-495: 28 mm
Maximum Specimen Size
- 60 mm × 50 mm
Vertical Specimen Stroke
- RD-315: 52 mm
- RD-475: 60 mm
- RD-495: 70 mm
Voltage and Frequency
- RD-315 / RD-495: AC 220V±10%, 50Hz (AC 110V±10%, 60Hz optional)
Research Domain
- Cancer Research
- Cell Biology
- Developmental Biology
- Histopathology
- Neuroscience
- Pathology
- Toxicology
Species
- Cat
- Dog
- Gerbil
- Hamster
- Pig
- Rabbit
- Mouse
- Rat
- Guinea pig
Automation Level
- Manual
Section Thickness Range
- RD-315: 0.5–60 µm
- RD-475: 1–60 µm
- RD-495: 1–60 µm
Specimen Angle
- Adjustable on three axes
Guide Rail Type
- Imported cross-roller guide rails
Motion Mechanism
- Screw motion mechanism
Specimen Retraction
- RD-315: Yes
- RD-475: 50 µm
- RD-495: 90 µm (optional)
Specimen Holder System
- Replaceable — paraffin block clamp and cassette clamp
Precision
- ±1%
Section Thickness Increments
- RD-315: 0.5 µm (0–2 µm) / 1 µm (2–10 µm) / 2 µm (10–20 µm) / 5 µm (20–60 µm)
- RD-495: 1 µm (0–20 µm) / 5 µm (20–60 µm)
Trimming Thickness Range
- RD-475: 0–60 µm
- RD-495: 15–35 µm
Blade Holder Angle
- RD-475: 0°–15° adjustable
Dimensions (W×D×H)
- RD-315: 565×440×285 mm
- RD-475: 555×450×320 mm
- RD-495: 590×500×330 mm
Net Weight
- RD-315: 28 kg
- RD-475: 45 kg
- RD-495: 37 kg
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