Research data · Disease model and test
Open field in Alzheimer disease research
From 2021 to 2025, 185 animal research papers on Alzheimer disease mentioned the open field in their title or abstract.
That is 6.4 times the 29 papers of 2011 to 2015. Between the same two periods, the papers on Alzheimer disease that mention any of the 90 tests we count grew more slowly, to 2.8 times as many.
Papers by year
Animal research papers on Alzheimer disease that mention the open field, by year, 2001 to 2026
The 2026 bar counts papers added to PubMed by November 8, 2026.
- Papers in a full year
- 2026 so far
Show the counts for each year
| Year | Papers |
|---|---|
| 2001 | 3 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 6 |
| 2010 | 7 |
| 2011 | 3 |
| 2012 | 1 |
| 2013 | 3 |
| 2014 | 12 |
| 2015 | 10 |
| 2016 | 18 |
| 2017 | 11 |
| 2018 | 13 |
| 2019 | 24 |
| 2020 | 24 |
| 2021 | 24 |
| 2022 | 34 |
| 2023 | 40 |
| 2024 | 35 |
| 2025 | 52 |
| 2026 (part year) | 44 |
Which species the papers used
Each bar is a share of the 185 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.
Species
Tests mentioned alongside the open field
Each bar is one test, with how many of the 185 papers also mention it, and what share that is. Of these papers, 20 (11%) mention no other test.
The 12 tests these papers mention most
Which papers count
A paper counts here when it is animal research, mentions the open field in its title or abstract, and studies Alzheimer disease.
We tell whether a paper studies Alzheimer disease from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.
The page on Alzheimer disease research names the subject headings we count as Alzheimer disease. Download the test list for the search terms we used for the open field, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.
More tests and disease models
Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.
Papers on Alzheimer disease that mention other tests
- Morris water maze 1,456 papers
- Novel object recognition 568 papers
- Y-maze 471 papers
- Passive avoidance 262 papers
- Elevated plus maze 143 papers
- Fear conditioning 125 papers
- Barnes maze 96 papers
- Treadmill running 73 papers
- Rotarod 56 papers
- T-maze 55 papers
- Object location test 49 papers
- Forced swim test 48 papers
- Radial arm maze 47 papers
- Nest building 41 papers
- Wheel running 36 papers
- Tail suspension test 30 papers
Papers on other disease models that mention the open field
- Anxiety 982 papers
- Depression 952 papers
- Cognitive impairment and dementia 493 papers
- Psychological stress 384 papers
- Parkinson disease 232 papers
- Pain conditions 199 papers
- Stroke and brain ischemia 159 papers
- Brain injury 107 papers
- Sleep loss and sleep disorders 93 papers
- Substance use disorders 93 papers
- Epilepsy and seizures 90 papers
- Autism spectrum disorder 84 papers
- Obesity and high-fat diet 75 papers
- Diabetes 72 papers
- Schizophrenia and psychosis 63 papers
- Aging 58 papers
- Post-traumatic stress 52 papers
- Spinal cord injury 41 papers
- Attention deficit hyperactivity disorder 34 papers
The page on the open field counts all the papers that mention it, whatever they study. The page on Alzheimer disease research ranks the tests by their papers on Alzheimer disease.
How to cite
APA
ConductScience. (2026, November 10). Open field in Alzheimer disease research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/alzheimers-disease/open-field
BibTeX
@misc{conductscience_alzheimers_disease_open_field_2026,
author = {{ConductScience}},
title = {Open field in Alzheimer disease research},
year = {2026},
month = nov,
url = {https://conductscience.com/resources/data/behavioral-tests/models/alzheimers-disease/open-field},
note = {Data set, released November 10, 2026},
}Open field apparatus in our store
In the test battery tool, pick every test your study will run and add the apparatus for all of them to one quote.
