Research data ยท Disease model and test

Social interaction test in depression research

From 2021 to 2025, 72 animal research papers on depression mentioned the social interaction test in their title or abstract.

That is 3.0 times the 24 papers of 2011 to 2015. Between the same two periods, the papers on depression that mention any of the 90 tests we count grew more slowly, to 1.5 times as many.

72 papers on depression from 2021 to 2025 mentioned the social interaction test
3% of the papers on depression that mention any test mention the social interaction test
15% of the papers that mention the social interaction test are on depression
3.0 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on depression that mention the social interaction test, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20011
20021
20030
20042
20052
20061
20072
20083
20092
20105
20114
20124
20132
20147
20157
20169
201711
20186
201920
202010
202117
202218
20237
202412
202518
2026 (part year)11

Papers on depression that mention the social interaction test fell from 17 in 2021 to 7 in 2023, then rose to 18 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 72 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
58 papers 81%
Rat
16 papers 22%
Zebrafish
1 paper 1%

Tests mentioned alongside the social interaction test

Each bar is one test, with how many of the 72 papers also mention it, and what share that is. Of these papers, 4 (6%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions the social interaction test in its title or abstract, and studies depression.

We tell whether a paper studies depression from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on depression research names the subject headings we count as depression. Download the test list for the search terms we used for the social interaction test, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

Papers on other disease models that mention the social interaction test

The page on the social interaction test counts all the papers that mention it, whatever they study. The page on depression research ranks the tests by their papers on depression.

How to cite

APA

ConductScience. (2026, November 10). Social interaction test in depression research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/depression/social-interaction-test

BibTeX

@misc{conductscience_depression_social_interaction_test_2026,
  author = {{ConductScience}},
  title = {Social interaction test in depression research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/behavioral-tests/models/depression/social-interaction-test},
  note = {Data set, released November 10, 2026},
}

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