Biochemistry at UT Southwestern Medical Center

Leads a grant in this department

40 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. McKnight, Steven L

   Leads 2 awards · $4,722,935

   • 5P01CA095471-09Department: NIH department code

     A Concerted Chemical, Biophysical and Molecular Biological Attack of Intracellul*
     $3,462,018

     award amount
   • 5R01MH087986-02Department: NIH department code

     Discovery, characterization and preclinical development of pro-neurogenic drugs
     $1,260,917

     award amount

2. Roth, Michael G

   Leads 2 awards · $2,055,265

   • 5RC2CA148225-02Department: NIH department code

     A Concerted Attack on Patient Specific Oncogenic Vulnerabilities in Lung Cancer
     $1,644,663

     award amount
   • 1S10RR027805-01Department: NIH department code

     Echo 555 Acoustical Droplet Ejection System for High-throughput Screening
     $410,602

     award amount

3. Olson, Eric N

   Leads 3 awards · $1,713,465

   • 5R01HL083371-05Department: NIH department code

     Control of Cardiac Gene Expression Through Regulated Transcriptional Coactivators
     $657,720

     award amount
   • 5R01HL093039-02Department: NIH department code

     MicroRNA Control of Cardiac Gene Expression, Function and Disease
     $538,510

     award amount
   • 5R01HL077439-07Department: NIH department code

     Genetic Dissection of Cardiogenesis
     $517,235

     award amount

4. Liu, Qinghua

   Leads 3 awards · $949,526

   • 5RC1GM091286-02Department: NIH department code

     Biochemical Studies of Drosophila RNA-induced Silencing Complex
     $383,000

     award amount
   • 5R01GM078163-05Department: NIH department code

     Molecular Mechanism of Small RNA-induced RNA Silencing
     $286,752

     award amount
   • 5R01GM084010-03Department: NIH department code

     Regulatory Mechanisms of RNA Interferance
     $279,774

     award amount

5. Chuang, David T

   Leads 4 awards · $921,652

   • 5R01DK062306-07Department: NIH department code

     Structure and Function of Mitochondrial Protein Kinases
     $373,032

     award amount
   • 5R01DK026758-32Department: NIH department code

     Inborn Errors of Metabolism in Cell Culture
     $369,760

     award amount
   • 3R01DK062306-06A2S1Department: NIH department code

     Structure and Function of Mitochondrial Protein Kinases
     $100,000

     award amount
   • 3R01DK026758-31S1Department: NIH department code

     Inborn Errors of Metabolism in Cell Culture
     $78,860

     award amount

6. Fontoura, Beatriz Ma

   Leads 2 awards · $838,250

   • 1R01AI079110-01A1Department: NIH department code

     Using Chemical Biology to Interfere with the Influenza Virus Life Cycle
     $419,125

     award amount
   • 1R01AI089539-01Department: NIH department code

     Novel Inhibitors of Viral Replication
     $419,125

     award amount

7. Rizorey, Jose

   Leads 2 awards · $815,560

   • 5R01NS040944-10Department: NIH department code

     Synaptotagmin and C2-domains: structure and function
     $409,922

     award amount
   • 5R01NS037200-13Department: NIH department code

     Neurotransmitter release machinery: structure and function
     $405,638

     award amount

8. De Brabander, Jef Karel

   Leads 2 awards · $740,281

   • 5RC1NS068963-02Department: NIH department code

     Development of Small Molecule Orexin Receptor Agonists for Treating Narcolepsy
     $487,799

     award amount
   • 5R01CA090349-10Department: NIH department code

     Chemistry and Biology of Antitumor Natural Products
     $252,482

     award amount

9. Mendelson, Carole R.

   Leads 2 awards · $710,653

   • 5R01HL050022-17Department: NIH department code

     Mechanisms in the Regulation of SP-A Gene Expression
     $472,903

     award amount
   • 2R56DK031206-27Department: NIH department code

     Cellular Mechanisms in the Induction of Aromatase
     $237,750

     award amount

10. Orth, Kim

    Leads 2 awards · $707,110

    • 1R01AI087808-01Department: NIH department code

      Analysis of an orchestrated cell death mediated by Vibrio parahaemolytics T3SS1
      $396,250

      award amount
    • 5R01AI056404-08Department: NIH department code

      Biochemical Characterization of Yersinia Effector YopJ
      $310,860

      award amount

11. Garrard, William

    Leads 2 awards · $694,231

    • 5R01AI067906-04Department: NIH department code

      Reorganization of Higher-Order Chromatin Structures During Igk Gene Activation
      $381,193

      award amount
    • 2R01GM029935-26A2Department: NIH department code

      Function of the Subunits of Eukaryotic Chromosomes
      $313,038

      award amount

12. Lin, Rueyling

    Leads 2 awards · $639,748

    • 2R01HD037933-11Department: NIH department code

      Transcriptional Regulation by the Wnt Effector POP-1
      $328,888

      award amount
    • 5R01GM084198-02Department: NIH department code

      CCCH zinc-finger proteins and transcriptional repression in germline blastomeres
      $310,860

      award amount

13. Kliewer, Steven A.

    Leads 2 awards · $610,782

    • 5R01DK067158-07Department: NIH department code

      Regulation of Metabolism by the Hormone FGF15/19
      $373,032

      award amount
    • 1R56DK089600-01Department: NIH department code

      The PPARgamma-FGF21 Signaling Pathway: Its Role in Thiazolidinedione Drug Action
      $237,750

      award amount

14. Avery, Leon

    Leads 2 awards · $599,050

    • 1R01DK083593-01A1Department: NIH department code

      Satiety signaling in Caenorhabditis elegans
      $301,150

      award amount
    • 5R37HL046154-20Department: NIH department code

      Genetics of nematode pharyngeal muscle excitability
      $297,900

      award amount

15. Chiang, Cheng-Ming

    Leads 2 awards · $581,194

    • 5R01CA124760-04Department: NIH department code

      Regulation of p53 Transcription by Viral Oncoproteins & Covalent Modifications
      $298,300

      award amount
    • 5R01CA103867-08Department: NIH department code

      E2-Cellular Complexes in HPV Chromatin Transcription
      $282,894

      award amount

16. Macdonald, Raymond J.

    Leads 2 awards · $567,320

    • 5R01DK061220-07Department: NIH department code

      Transcriptional Regulators of Exocrine Pancreatic Development
      $373,032

      award amount
    • 5R21HD060222-02Department: NIH department code

      Determining the developmental progression of PTF1 targets by ChIP-seq
      $194,288

      award amount

17. Bruick, Richard K

    Leads 2 awards · $557,534

    • 1R01HL102481-01Department: NIH department code

      Study of an iron-responsive E3 ligase regulating mammalian iron homeostasis
      $314,000

      award amount
    • 5R01CA115962-05Department: NIH department code

      Regulation of the Hypoxia Inducible Factor (HIF)
      $243,534

      award amount

18. Rosen, Michael K

    Leads 2 awards · $551,775

    • 5R01GM056322-14Department: NIH department code

      Structural Study of GTPase Regulators and Effectors
      $297,575

      award amount
    • 1S10RR026461-01Department: NIH department code

      600MHz Varian VNMRS Console Upgrade
      $254,200

      award amount

19. Buszczak, Michael

    Leads 2 awards · $533,067

    • 5R01GM086647-02Department: NIH department code

      Decoding Stem Cell Chromatin Using Drosophila
      $295,317

      award amount
    • 1R21HD065174-01Department: NIH department code

      Characterization of Drosophila Germline Stem Cell Chromatin Using ChIP-Seq
      $237,750

      award amount

20. Chen, Chuo

    Leads 2 awards · $497,232

    • 5R01GM079554-04Department: NIH department code

      Asymmetric Synthesis of Biologically Active Marine Natural Products
      $265,785

      award amount
    • 3R01GM079554-04S1Department: NIH department code

      Asymmetric Synthesis of Biologically Active Marine Natural Products
      $231,447

      award amount

21. Otwinowski, Zbyszek

    Leads 1 award · $478,516

    • 5R01GM053163-16Department: NIH department code

      The Crystallography of Macromolecules
      $478,516

      award amount

22. Gardner, Kevin H

    Leads 2 awards · $423,103

    • 5R01GM081875-09Department: NIH department code

      Structural studies of PAS domain signaling mechanisms
      $301,021

      award amount
    • 5T32GM008297-22Department: NIH department code

      Molecular Biophysics Predoctoral Training Program
      $122,082

      award amount

23. Falck, John R.

    Leads 1 award · $407,684

    • 5R01GM031278-26Department: NIH department code

      Novel Eicosanoids: Synthesis and Function
      $407,684

      award amount

24. Tallquist, Michelle D

    Leads 1 award · $392,500

    • 5R01HL074257-06Department: NIH department code

      PDGF Receptor Signaling in Mammalian Development
      $392,500

      award amount

25. McKearin, Dennis M

    Leads 1 award · $349,718

    • 5R01GM045820-20Department: NIH department code

      GERM CELL DIFFERENTIATION IN DROSOPHILA
      $349,718

      award amount

26. Cleaver, Ondine B

    Leads 2 awards · $343,748

    • 5R01DK079862-04Department: NIH department code

      Endothelial signals during organogenesis
      $281,795

      award amount
    • 3R01DK079862-04S1Department: NIH department code

      Endothelial Signals During Organogenesis
      $61,953

      award amount

27. Macmillan, John B

    Leads 1 award · $328,888

    • 1R01CA149833-01Department: NIH department code

      Marine Actinomycetes as a Resource for Anticancer Natural Products
      $328,888

      award amount

28. Word, Ruth A

    Leads 1 award · $328,888

    • 1R01HD064824-01A1Department: NIH department code

      Protease regulation and integrity of connective tissues of the pelvic floor
      $328,888

      award amount

29. Hsieh, Jenny

    Leads 1 award · $318,632

    • 5R01AG032383-02Department: NIH department code

      Epigenetic regulation of adult neurogenesis
      $318,632

      award amount

30. Tu, Benjamin P

    Leads 1 award · $317,000

    • 1R01GM094314-01A1Department: NIH department code

      Metabolic signals driving cell growth and proliferation
      $317,000

      award amount

31. Grishin, Nick V.

    Leads 1 award · $309,075

    • 1R01GM094575-01Department: NIH department code

      Computational methods for structural-functional studies of proteins
      $309,075

      award amount

32. Li, Bing

    Leads 1 award · $301,150

    • 1R01GM090077-01A1Department: NIH department code

      Mechanisms for chromatin modification during transcription elongation
      $301,150

      award amount

33. Zou, Hui

    Leads 1 award · $295,317

    • 5R01GM081466-04Department: NIH department code

      Investigate the downstream mechanisms and upstream regulation of acetyltransferas
      $295,317

      award amount

34. Uyeda, Kosaku

    Leads 1 award · $237,750

    • 2R01DK063948-05A2Department: NIH department code

      Carbohydrate Regulation of Hepatic Gene Expression
      $237,750

      award amount

35. Winkler, Wade

    Leads 1 award · $236,254

    • 5R01GM081882-04Department: NIH department code

      Regulation of Magnesium Homeostasis in Bacillus subtilis
      $236,254

      award amount

36. Goldsmith, Elizabeth J.

    Leads 1 award · $60,000

    • 3R01DK046993-16S1Department: NIH department code

      Interactions and Dual Phosphorylation in MAP Kinase Cascades
      $60,000

      award amount

37. Millay, Douglas Paul

    Leads 1 award · $50,474

    • 1F32AR059484-01Department: NIH department code

      Role of microRNA-206 in skeletal muscle regeneration
      $50,474

      award amount

38. O'Rourke, Jason Robert

    Leads 1 award · $47,606

    • 1F32AR059485-01Department: NIH department code

      MicroRNA-29 in postnatal skeletal muscle development and disease
      $47,606

      award amount

39. Zoltowski, Brian David

    Leads 1 award · $47,606

    • 1F32GM090671-01Department: NIH department code

      Structural Dynamics of Pas Domain Containing Transcription Factors
      $47,606

      award amount

40. Quiat, Daniel Simon

    Leads 1 award · $27,780

    • 1F30HL103013-01Department: NIH department code

      The role of miR-210 in cardiomyocyte metabolism following myocardial infarction
      $27,780

      award amount