Biochemistry at UT Southwestern Medical Center

Leads a grant in this department

40 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Bassel-Duby, Rhonda

   Leads 3 awards · $2,715,819

   • 5P50HD087351-08Department: NIH department code

     Myoediting of Duchenne Muscular Dystrophy
     $1,605,786

     award amount
   • 1R01HL157281-01A1Department: NIH department code

     Transcriptional Control of Neonatal Heart Regeneration
     $565,036

     award amount
   • 5R01HL130253-07Department: NIH department code

     Deciphering the role of a novel micropeptide in cardiac function and dysfunction
     $544,997

     award amount

2. Phillips, Margaret A.

   Leads 4 awards · $1,969,331

   • 5R01AI155784-02Department: NIH department code

     Optimization of novel phenotypic screening hits for treatment of Malaria
     $737,236

     award amount
   • 5R01AI103947-10Department: NIH department code

     Lead Optimization of DHODH Inhibitors for Malaria
     $723,733

     award amount
   • 5R01AI034432-27Department: NIH department code

     POLYAMINE AND TRYPANOTHIONE METABOLISM IN TRYPANOSOMA BRUCEI
     $445,837

     award amount
   • 3R01AI155784-02S1Department: NIH department code

     Optimization of novel phenotypic screening hits for treatment of Malaria
     $62,525

     award amount

3. Cleaver, Ondine B

   Leads 4 awards · $1,550,627

   • 5R01DK121408-04Department: NIH department code

     Hippo suppression of NFkB controls pancreas morphogenesis and beta cell fate
     $405,000

     award amount
   • 5R01DK116622-04Department: NIH department code

     Role of Afadin in 3D epithelial plexus morphogenesis and beta cell mass
     $401,280

     award amount
   • 5R01HL126518-07Department: NIH department code

     Molecular regulation of Rho and Ras family GTPase activity controls vascular lumen formation.
     $391,875

     award amount
   • 5R01DK124393-03Department: NIH department code

     Renal vascular remodeling and arteriogenesis: cues from smooth muscle progenitor cells
     $352,472

     award amount

4. Pieper, Andrew A

   Leads 1 award · $1,345,312

   • 5RM1GM142002-02Department: NIH department code

     Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and Regeneration
     $1,345,312

     award amount

5. Joachimiak, Lukasz A.

   Leads 1 award · $1,230,000

   • 1RF1AG078888-01Department: NIH department code

     J-domain protein conformational selectivity for tau in disease
     $1,230,000

     award amount

6. Chen, Elizabeth H

   Leads 4 awards · $1,141,455

   • 5R35GM136316-03Department: NIH department code

     Decoding the mechanisms of cell-cell fusion
     $410,000

     award amount
   • 5R01AR075005-03Department: NIH department code

     Investigating mechanisms of vertebrate myoblast fusion using zebrafish as a model
     $357,192

     award amount
   • 5R01AR053173-16Department: NIH department code

     Molecular Mechanisms of Myoblast Fusion
     $352,836

     award amount
   • 3R35GM136316-03S1Department: NIH department code

     Decoding the mechanisms of cell-cell fusion
     $21,427

     award amount

7. Zhang, Chun-Li

   Leads 2 awards · $903,739

   • 1R01NS127375-01A1Department: NIH department code

     PAX6-induced adult neurogenesis
     $480,486

     award amount
   • 5R01NS117065-03Department: NIH department code

     In vivo reprogramming of NG2 glia for neurogenesis
     $423,253

     award amount

8. Tu, Benjamin P

   Leads 3 awards · $833,608

   • 5R35GM136370-03Department: NIH department code

     Metabolic signals regulating cell growth versus survival
     $402,168

     award amount
   • 5R01NS115546-04Department: NIH department code

     Redox regulation of protein functions linked to neurodegeneration
     $358,750

     award amount
   • 3R01NS115546-04S1Department: NIH department code

     Redox regulation of protein functions linked to neurodegeneration
     $72,690

     award amount

9. Buszczak, Michael

   Leads 3 awards · $806,951

   • 1R01AG079513-01Department: NIH department code

     Characterization of how mRNA translation influences reproductive aging
     $336,200

     award amount
   • 1R35GM144043-01Department: NIH department code

     Genetic Dissection of Germ Cell Differentiation and Function
     $265,751

     award amount
   • 5R21HD105349-02Department: NIH department code

     Developing human gonad organoids to promote germ cell differentiation
     $205,000

     award amount

10. Wu, Jun

    Leads 2 awards · $693,168

    • 1R01HD103627-01A1Department: NIH department code

      Dissect the mechanisms underlying interspecies pluripotent stem cell competition
      $352,600

      award amount
    • 5R01GM138565-02Department: NIH department code

      Dissect formative pluripotency using cultured pluripotent stem cells
      $340,568

      award amount

11. Douglas, Peter Mahan

    Leads 2 awards · $668,000

    • 1R01AG076529-01Department: NIH department code

      Lipid sensing through G protein geranylgeranylation
      $335,900

      award amount
    • 5R01AG061338-04Department: NIH department code

      Heat Shock Factor mediates actin phosphorylation in tissue integrity and age
      $332,100

      award amount

12. Jewell, Jenna L

    Leads 2 awards · $665,325

    • 1R01GM130792-01A1Department: NIH department code

      Deciphering the Molecular Mechanisms by which PKA inhibits mTORC1
      $344,400

      award amount
    • 5R01GM129097-05Department: NIH department code

      Glutamine Sensing by mTORC1
      $320,925

      award amount

13. Tambar, Uttam Krishan

    Leads 4 awards · $614,772

    • 5R01GM102604-11Department: NIH department code

      Stereoselective Photochemistry for the Synthesis of Bioactive Molecules
      $338,632

      award amount
    • 3R01GM102604-11S2Department: NIH department code

      Stereoselective Photochemistry for the Synthesis of Bioactive Molecules
      $196,600

      award amount
    • 3R01GM102604-10S1Department: NIH department code

      Stereoselective Photochemistry for the Synthesis of Bioactive Molecules
      $39,770

      award amount
    • 3R01GM102604-11S1Department: NIH department code

      Stereoselective Photochemistry for the Synthesis of Bioactive Molecules
      $39,770

      award amount

14. Mahendroo, Mala S.

    Leads 1 award · $604,905

    • 5R01HL050022-28Department: NIH department code

      Mechanisms in the Regulation of SP-A Gene Expression - Renewal - 1 - Resubmission
      $604,905

      award amount

15. Mu, Ping

    Leads 2 awards · $495,332

    • 5R37CA258730-02Department: NIH department code

      Elucidating the Molecular Role of SYNCRIP in Prostate Cancer and AR Targeted Therapy Resistance
      $408,360

      award amount
    • 3R37CA258730-02S1Department: NIH department code

      Elucidating the Molecular Role of SYNCRIP in Prostate Cancer and AR Targeted Therapy Resistance
      $86,972

      award amount

16. McKnight, Steven L

    Leads 1 award · $486,000

    • 5R35GM130358-04Department: NIH department code

      A solid state conceptualization of information transfer from gene to message to protein
      $486,000

      award amount

17. Kohler, Jennifer J

    Leads 1 award · $480,413

    • 1R35GM145599-01Department: NIH department code

      Function and regulation of epithelial glycosylation
      $480,413

      award amount

18. Nam, Yunsun

    Leads 1 award · $440,678

    • 1R01CA258589-01A1Department: NIH department code

      Small molecules to target the RNA methyltransferase complex METTL3/METTL14
      $440,678

      award amount

19. Liszczak, Glen

    Leads 1 award · $410,000

    • 1R35GM147140-01Department: NIH department code

      Regulation and function of site-specific protein poly-ADP-ribosylation
      $410,000

      award amount

20. Siegwart, Daniel John

    Leads 1 award · $391,721

    • 1R01CA269787-01Department: NIH department code

      Multiplexed nanoparticle delivery to increase CRISPR/Cas gene editing for enhanced cancer therapy
      $391,721

      award amount

21. Chen, Chuo

    Leads 1 award · $380,217

    • 5R01CA226419-04Department: NIH department code

      Explore the therapeutic potential of small-molecule immune modulators
      $380,217

      award amount

22. Chen, Zhijian J

    Leads 1 award · $373,862

    • 1OT2CA278683-01Department: NIH department code

      eDyNAmiC-TEXASSW
      $373,862

      award amount

23. Kliewer, Steven A.

    Leads 1 award · $369,000

    • 5R01AA028473-03Department: NIH department code

      Coordinate Regulation of an Alcohol Protective Response by the Liver-derived Hormone FGF21
      $369,000

      award amount

24. Orth, Kim

    Leads 1 award · $369,000

    • 5R35GM134945-03Department: NIH department code

      Biochemistry, biology and diversity of Fic domains
      $369,000

      award amount

25. Liu, Ning

    Leads 1 award · $352,836

    • 5R01AR071980-05Department: NIH department code

      Role of Twist2+ myogenic progenitor cells in adult skeletal muscle
      $352,836

      award amount

26. Tagliabracci, Vincent Scott

    Leads 1 award · $324,518

    • 5R01GM135189-03Department: NIH department code

      Antioxidant signaling by protein AMPylation
      $324,518

      award amount

27. Qin, Tian

    Leads 1 award · $324,060

    • 5R01GM141088-02Department: NIH department code

      Development of Sulfur-Based Reactions with Translational Applications
      $324,060

      award amount

28. Sun, Lu

    Leads 2 awards · $320,679

    • 5R00EY029330-05Department: NIH department code

      Identification of a novel pathway that regulates optic nerve myelination and remyelination
      $237,621

      award amount
    • 3R00EY029330-05S1Department: NIH department code

      Identification of a novel pathway that regulates optic nerve myelination and remyelination
      $83,058

      award amount

29. Yu, Haiyang

    Leads 1 award · $249,000

    • 4R00NS114162-03Department: NIH department code

      Determining the molecular organization of TDP-43 in liquid spherical annuli and establishing a designer gene therapeutic strategy to degrade TDP-43 aggregates
      $249,000

      award amount

30. Kohler, Jennifer J

    Leads 1 award · $161,169

    • 5T32GM127216-04Department: NIH department code

      Chemistry-Biology Interface T32
      $161,169

      award amount

31. Sreelatha, Anju

    Leads 1 award · $149,035

    • 5K01DK123194-03Department: NIH department code

      Novel mechanisms of redox signaling in acute kidney injury
      $149,035

      award amount

32. Hsieh, Ting-Sung

    Leads 1 award · $100,000

    • 1K99GM147532-01Department: NIH department code

      Phosphatidylinositol 3-Phosphate in the Regulation of Autophagic Membrane Remodeling
      $100,000

      award amount

33. Cui, Miao

    Leads 1 award · $94,880

    • 5K99HL153683-02Department: NIH department code

      Dissecting the cytoprotective role of NRF1 in heart regeneration and repair
      $94,880

      award amount

34. Yu, Yonghao

    Leads 1 award · $88,659

    • 1R01NS122533-01A1Department: NIH department code

      A Chemical Footprinting Approach towards Poly-ADP-Ribosylation-regulated Biomolecular Condensation
      $88,659

      award amount

35. Rodriguez-Tirado, Carla Sofia

    Leads 1 award · $38,017

    • 1F31CA261019-01A1Department: NIH department code

      Dissecting the role of UBE2J1 in prostate cancer
      $38,017

      award amount

36. Bali, Sofia

    Leads 1 award · $37,674

    • 1F31NS127513-01Department: NIH department code

      Inhibiting fibrillation of Tau through changes in local intramolecular interactions
      $37,674

      award amount

37. Schmitz, Daniel Andrew

    Leads 1 award · $37,674

    • 1F31NS125906-01A1Department: NIH department code

      Study of mitochondria-depleted pluripotent stem cells in development and disease
      $37,674

      award amount

38. Fang, Yan

    Leads 1 award · $37,263

    • 1F99CA274647-01Department: NIH department code

      Enhancing the antitumor effect of radiation therapy by targeting the cGAS-STING pathway
      $37,263

      award amount

39. Cano Hernandez, Karla Gabriela

    Leads 1 award · $35,664

    • 1F31CA271675-01Department: NIH department code

      The Molecular function of ecto 5' nucleotidase in fusion-negative rhabdomyosarcoma
      $35,664

      award amount

40. Tatge, Lexus Marc

    Leads 1 award · $33,394

    • 5F31GM140620-02Department: NIH department code

      Defining the cytoplasmic sequestration of Caenorhabditis elegans orphan nuclear receptor 49 on trafficking vesicles
      $33,394

      award amount