Elevated Plus Maze citations

Maze Engineers, part of ConductScience, makes this product. Each study below names the product or its maker in the sentence quoted under its title.

13 papers, preprints and theses as of

See the Elevated Plus MazeAll citations
APP-mediated intracellular signaling rescues sleep impairment and blood-brain barrier leakage in Alzheimer's disease mouse model.

Clémentine Puech, Anjana Sadanand, Neil Coleman et al. · Alzheimer's & Dementia · 2026

From the methods
...(NOR) and Elevated Plus Maze (EPM) tests. Maze equipment for EPM and NOR was obtained from Maze Engineers (Cambridge, MA, USA).
Behavioural hyperactivity and risk-taking in young-adult male mice correlate with increased dopamine release in dorsal, but not ventral, striatum

Sean Coady, Anusha Kamesh, Christina Gentle et al. · Preprint on bioRxiv · 2026

From the methods
The EPM apparatus (Maze Engineers Inc. (USA) was in the center of a large metallic enclosure (2 x 2 x 2m) surrounded by dark curtains to avoid direct light.
Characterizing the Role of Cardiolipin in Reward Behavior Using Elamipretide

L S Dias · Thesis at University of North Carolina at Chapel Hill · 2026

From the methods
The EPM consisted of a plus-shaped plexiglass apparatus (Maze Engineers) with 25 cm x 6 cm arms and a closed arm height of 16 cm (Fig. 2A).
Doxazosin Alleviates Chronic Orofacial Pain

Karin N. Westlund, Bingye Xue, Sabrina L. McIlwrath · International Journal of Molecular Sciences · 2026

From the methods
...with high, protective walls (30 cm high) at the perimeter, and two open ones, lacking barriers (Maze Engineers, Skokie, IL, USA).
TNF-mediated hilar interneuron loss and aberrant granule cell migration are associated with chronic cognitive deficits following TBI

Elizabeth A. Harris, Sabrina Budianto, Sreejita Arnab et al. · Brain, Behavior, and Immunity · 2026

From the methods
A black Elevated Plus Maze (35cm arm length, 5cm arm width, 20cm wall height, 61cm stand height) (Maze Engineers, Skokie, IL) was used to measure anxiety and risk assessment behavior in mice.
Cognitive Function, Sleep, and Neuroinflammatory Markers in Mice Exposed to Very Long-Term Intermittent Hypoxia

Clementine Puech, Mohammad Badran, Max B Barrow et al. · International Journal of Molecular Sciences · 2025

From the methods
...set-ups were cleaned with 70% ethanol to prevent odor cues. All the mazes were purchased from Maze Engineers (Cambridge, MA, USA).
Profiling of research domain criteria-based behaviors following single prolonged stress in male C57BL/6J mice.

Krysten P O'Hara, Savanna M King, Rachel D Penrod et al. · Stress · 2025

From the methods
>). Briefly, mice were placed onto the EPM (matte gray acrylic; wall height: 20 cm, arm length: 35 cm, arm width: 5 cm; Conduct Science; Skokie, IL) into the central zone between the closed and open arms with its head facing away from the experimenter tow
Representations of stimulus features in the ventral hippocampus.

Jeremy S Biane, Max A Ladow, Austin Fan et al. · Neuron · 2025

From the methods
Mice were placed in a standard EPM sized maze (13.5” height of maze from floor, 25” full length of each arm type, 2” arm width, 7” tall closed arms, with 0.5” tall/wide ledges on the open arms made by Maze Engineers, Skokie, IL), with 450 light lux centered over the open arms to promote avoidance.
Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA

Mohammad Badran, Clementine Puech, Max B. Barrow et al. · Sleep Medicine · 2023

From the methods
All mazes were purchased from Maze Engineers (Cambridge, MA, USA).
Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice

Clementine Puech, Mohammad Badran, Max B Barrow et al. · Sleep · 2023

From the methods
All mazes were purchased at Maze Engineers (Cambridge, MA).
Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period

Clementine Puech, Mohammad Badran, Alexandra R Runion et al. · Neurobiology of Sleep and Circadian Rhythms · 2022

From the methods
...set-ups were cleaned with ethanol 70% to prevent odor cues. All mazes were purchased at Maze Engineers (Cambridge, MA, USA).
I. Antidepressants and sexual behavior: Weekly ketamine injections increase sexual behavior initially in female and male rats

Fay A. Guarraci, Maryam Ali, Chantal M.F. Gonzalez et al. · Pharmacology Biochemistry and Behavior · 2020

From the methods
The two open arms are 10 cm-wide platforms that extend away from the center of the maze, whereas the two closed arms are 10 cm-wide platforms that are surrounded by 30 cm-high walls (Maze Engineers).
The Behavioral Effects of Oral Psychostimulant Ingestion on a Laboratory Rat Sample: An Undergraduate Research Experience. Journal of

Howerter, D. D., Larson, J. G., Hill, E. M. · Undergraduate Neuroscience Education · 2018

From the methods
Purchased commercially, the acquisition of a simple EPM, designed for rat use, as described previously, would cost a university department approximately $2,200.00 (based on pricing information from Maze Engineers, Braintree Scientific Inc., Stoelting, and Kinder Scientific).