Fear Conditioning System citations

Maze Engineers, part of ConductScience, makes this product. Each study below names the product or its maker in the sentence quoted under its title.

13 papers and preprints as of

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive-Like Behaviors.

Kai Chen, Riya Gupta, Yosuke M Morizawa et al. · Advanced Science · 2026

From the methods
Fear conditioning: Fear conditioning was conducted in a conditioning chamber (Maze Engineers) with ANY‐maze recording.
Serotonergic circuit architecture underlies sex dimorphism in anxiogenic states

Noorya Yasmin Ahmed, Yillcer Molina, Alvaro Ballesteros Gonzalez et al. · Preprint on bioRxiv · 2026

From the methods
Contextual fear conditioning was performed using an acrylic chamber (17 × 17 × 25 cm) equipped with a shock-grid floor (Maze Engineers, USA), transparent walls, visual cues, and a 70% ethanol scent.
The exercise hormone irisin has neuroprotective effects in a mouse model of multiple sclerosis

Sina C. Rosenkranz, Joana F. da Rocha, Luis Moreira et al. · Nature Metabolism · 2026

From the methods
Mice were placed in a conditioning chamber (17 cm × 17 cm × 25 cm, Maze Engineers) with Plexiglas sides and a steel bar floor.
Genetically diverse mice exhibit divergent domain-specific, sex-dependent behavioral outcomes following exposure to early life stress

Jennifer Nguyen, Kevin Shimizu, Varvara Zlotnik et al. · PLOS ONE · 2025

From the methods
Fear procedures took place in a 17 × 17 × 25 cm chamber with transparent acrylic walls and a metal rod floor for shock delivery (MazeEngineers, Skokie, IL).
mWAKE in the Central Amygdala Regulates Fear Learning and Memory

Jiali Xiong, Anuradha Mehta, Qiang Liu et al. · The Journal of Neuroscience · 2025

From the methods
Fear conditioning (FC) tests were performed using the Fear Conditioning Chambers (Maze Engineers) and were performed within ZT0–2 or ZT12–14 windows.
Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.

Joana F da Rocha, Michelle L Lance, Renhao Luo et al. · Nature Neuroscience · 2025

From the methods
Mice were placed into a conditioning chamber (17 cm long × 17 cm wide × 25 cm high, Maze Engineers, Stokie, IL) with Plexiglas sidewalls and a floor consisting of steel bars.
Psilocybin Enhances Cued Fear Extinction and Extinction Recall in Stress-Naïve, Acutely Stressed, and Chronically Stressed Mice

John Razidlo, Noelle Cataldo, Cody J Wenthur · ACS Pharmacology & Translational Science · 2025

From the methods
Fear conditioning chambers and their paired software were purchased from Maze Engineers (Skokie, IL, USA).
Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau

Kai Chen, Yosuke M. Morizawa, Tal Nuriel et al. · Neuron · 2025

From the methods
Auditory-cued fear conditioning was conducted in a dedicated conditioning chamber (Maze Engineers), with behavior data recorded and analyzed using ANY-maze software.
2MDR, a Microcomputer-Controlled Visual Stimulation Device for Psychotherapy-Like Treatments of Mice

Isa Jauch, Jan Kamm, Luca Benn et al. · eNeuro · 2023

From the methods
...behavioral setups. We used our 2MDR system with a regular auditory fear conditioning (FC) system (Maze Engineers) and a TTL trigger unit (Maze Engineers).
Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline

Jing Tian, Lan Guo, Tienju Wang et al. · JCI Insight · 2023

From the methods
...was blinded during the tests. Experiments were performed using the fear-conditioning system from Maze Engineers.
Inhibition of unfolded protein response prevents post-anesthesia neuronal hyperactivity and synapse loss in aged mice

Kai Chen, Qiuping Hu, Riya Gupta et al. · Aging Cell · 2022

From the methods
Fear conditioning was conducted in a fear conditioning chamber (Maze Engineers). The ANY‐maze software (Stoelting) was used to control the delivery of tones and foot shocks.
Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation

Candela Barettino, Álvaro Ballesteros-Gonzalez, Andrés Aylón et al. · Frontiers in Cell and Developmental Biology · 2021

From the methods
Fear memory was tested using the Fear Conditioning system (Maze Engineers, Boston, USA) in an acrylic plastic cage of 17 × 17 × 25 cm placed over a shock generator grid.
Assaying Fear Memory Discrimination and Generalization: Methods and Concepts

Hadley C Bergstrom · Current Protocols in Neuroscience · 2020

From the paper
...fear conditioning systems available, including (Coulbourn Instruments, Whitehall PA, USA), MazeEngineers, (Boston MA, USA), Med Associates (St. Albans, VT USA), Stoelting Ugo Basile (Wood Dale, IL USA),...