Rodent Treadmill citations

Maze Engineers, part of ConductScience, makes this product. Each study below names the product or its maker in the sentence quoted under its title.

22 papers, preprints and theses as of

Cardiac metabolic remodeling drives dicarbonyl stress-induced mitochondrial dysfunction in experimental heart failure with preserved ejection fraction

Ankit Aryal, Parnia Mobasheran, Luther Bishop et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2026

From the methods
Exercise capacity was assessed using a motorized treadmill (MAZE Engineers, USA).
Chronic cold induces some similar effects to endurance exercise on body morphometrics and skeletal muscle structure in rats

Michelle Johannsen, Kristin O’Brien, S. Ryan Oliver · Journal of Comparative Physiology B · 2026

From the methods
The treadmill was equipped with lane boxes (Maze Engineers, 5 Lane Rat Treadmill, Skokie, IL) that permitted forward and backward movement to accommodate variations in pace.
Intracerebroventricular infusion of exercise donor plasma exosomes induces molecular changes indicating exercise-like adaptations in basal ganglia cells of older male rats

Bruce A. Citron, Kathleen E. Murray, Alexander Lemenze et al. · Frontiers in Aging Neuroscience · 2026

From the methods
eExosome male donor rats aged 9–10 weeks were continuously monitored while running on a 5-lane treadmill that was equipped with both a light signal and a tail shock (MazeEngineers, Skokie, IL).
MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats.

Olha Kravtsova, Yifan Tan, Vladislav Levchenko et al. · iScience · 2026

From the methods
...was assessed in male 7-week-old SSMlycd+/+ and SSMlycd+/- rats using a motor-driven treadmill (Maze Engineers, Skokie, IL).
Motor experience leads to structural changes in the adult male mouse inferior olive

Tara H. Turkki, Sophia Dubois, Hugo Hoedemaker et al. · Preprint on bioRxiv · 2026

From the methods
The mice were trained on a single-lane mouse treadmill (Maze Engineers, USA).
Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments

Bogna M Ignatowska-Jankowska, Lakshmipriya I Swaminathan, Tara H Turkki et al. · eNeuro · 2025

From the methods
...rim to track movement. TRM running tasks were conducted on a motorized single-lane treadmill (MazeEngineers), with markers attached to the belt at 20 cm intervals to monitor speed (Movie 5).
Combination of dietary fiber and exercise training improves fat loss in mice but does not ameliorate MASLD more than exercise alone

Artemiy Kovynev, Mikołaj M. Charchuta, Amina Begtašević et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2025

From the methods
Mice were trained on a rat treadmill with five lanes (MazeEngineers, Skokie, IL), allowing two to four cage mates to run together per lane, as previously described (13), with minor adjustments.
Compensatory changes after spinal cord injury in a remyelination deficient mouse model

S. B. Manesh, B. R. Kondiles, S. Wheeler et al. · Journal of Neurochemistry · 2025

From the methods
Once awake, mice were moved to a variable speed rodent treadmill (Maze Engineers) surrounded by six evenly spaced infrared Vero cameras (Vicon Motion Systems, Oxford, UK) recording at 320 frames/second.
Depending on intensity, exercise improved or worsened pathology in a model of prodromal Parkinson's disease.

Leonie Baldauf, Malte Feja, Milos Stanojlovic et al. · Npj Parkinson's Disease · 2025

From the methods
Mice were trained for running on a 5-lane motorized treadmill (Model 60A SM 400-LS-Z, maze engineers, USA).
Loss of adenylosuccinate synthetase 1 in mice recapitulates features of ADSS1 myopathy

Morgan E Kim, Kathryn M Yammine, Emily T Hickey et al. · Human Molecular Genetics · 2025

From the methods
Additional mice were aged to ~ 11 months and subjected to a premortem treadmill test where they were run to exhaustion on an automated single belt rodent treadmill (Maze Engineers).
Moderate Chronic Treadmill Exercise Slows Dopaminergic Neuron Loss in a Rat Model of Parkinson's Disease and Alters RNA Content of Circulating Plasma Exosomes

Bruce A Citron, Maynard Guzman, Bobak Shapdoor et al. · Journal of Neuroscience Research · 2025

From the methods
A 5‐lane MazeEngineers treadmill equipped with both a light signal and tail shock was used for exercise.
Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota.

Prabhat Upadhyay, Asmita Banstola, Brijesh Bhayana et al. · Advanced Science · 2025

From the methods
...period was implemented for all mice, with the initial settings of the shock grid at 0.9 mA (Maze Engineers Automated Treadmill, Skokie, IL, USA), after which a progressive exercise training regimen was...
Pretreatment of Mice with 830 nm Light Enhances Endurance During Acute Exercise.

Nashwa Cheema, Namrata Ghag, Linh Pham et al. · Muscles · 2025

From the methods
...acclimatized to the treadmill for 3 days. Briefly, they were placed on an unmoving treadmill (Maze Engineers, Skokie, IL, USA) for 1–3 min and then allowed to run at a speed of 10 m/min.
Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.

Khanh V Doan, Timothy S Luongo, Thato T Ts'olo et al. · Nature Cardiovascular Research · 2024

From the methods
To evaluate exercise capacity and endurance, mice were run on a treadmill system (Maze Engineers: Treadmill 2009, Model No. MZ-3.0-8-52) with a stepwise accelerating protocol at 10° incline.
Quantification of nutrient fluxes during acute exercise in mice.

Jessie Axsom, Tara TeSlaa, Won Dong Lee et al. · Cell Metabolism · 2024

From the methods
...all mice were acclimated to use a motorized treadmill (Maze Engineers, IL), as outlined in Table S1.
Baf155 regulates skeletal muscle metabolism via HIF-1a signaling

Jong-Seol Kang, Dongha Kim, Joonwoo Rhee et al. · PLOS Biology · 2023

From the methods
...to the treadmill (DJ2-242 Dual Treadmill, Daejong Instrument, Treadmill for 8 mice LT320, Maze engineers) before running tests.
Blood-Pool Stress MRI as a Tool for Identifying Early Biomarkers of Diabetic Heart Failure with Preserved Ejection Fraction

Sadi Loai · Thesis at University of Toronto · 2023

From the methods
All rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 minutes.
Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences

Sadi Loai, Xuetao Sun, Mansoor Husain et al. · Frontiers in Cardiovascular Medicine · 2022

From the methods
...3 post-induction (Table 1). In brief, rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 min.
Physical Training Reverses the Impaired Cardiac Autonomic Control and Exercise Tolerance Induced by Right-Side Vagal Denervation

Oleg V. Mamontov, Andrei A. Karpov, Sarkis M. Minasian et al. · IEEE Access · 2022

From the methods
In the first stage of the study, we assessed animals’ tolerance to physical exercises by the treadmill test performed on a 5-lane moving road (Maze Engineers, USA).
Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development

Milena Schönke, Zhixiong Ying, Artemiy Kovynev et al. · The FASEB Journal · 2022

From the methods
The mice were trained on a rat treadmill with five lanes (MazeEngineers, Skokie, Illinois), allowing 3–4 cage mates to run on one lane together which was observed to improve the motivation of the mice to run, when compared with solitary running.
Effect of exercise on peritoneal microenvironment and progression of ovarian cancer

Madeline J Morrisson, Fangfang Bi, Kevin Yang et al. · American Journal of Cancer Research · 2021

From the methods
An automated 5-lane mouse treadmill (Maze Engineers, Skokie, IL) was used in the forced running model.
Skeletal Muscle Microvascular Dysfunction Manifests Early in Diabetic Cardiomyopathy

Sadi Loai, Yu-Qing Zhou, Kyle D. W. Vollett et al. · Frontiers in Cardiovascular Medicine · 2021

From the methods
...at 3 months post-diabetes. All rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 min.