Zero Maze citations

Maze Engineers, part of ConductScience, makes this product. Each study below names the product or its maker in the sentence quoted under its title.

14 papers, preprints, protocols and theses as of

Autonomic C1 neurons promote anxiety via activation of vlPAG

Carlos Fernández-Peña, Rachel L. Pace, Lourds M. Fernando et al. · Neuron · 2026

From the key resources table
Elevated Zero Maze · Maze Engineers
Elevated Zero Maze for Animal Behavior Testing v1

Taryn E McFadden, Ann Sipe, Jennifer E Nyland · Protocol on protocols.io · 2026

From the paper
Elevated Zero Maze Apparatus [Maze Engineers]
Influence of sex, anxiety, and risk-taking behavior on opioid and alcohol polysubstance consumption patterns

Makenzie Patarino, Ziheng Christina Wang, Andrew Byungwook Kim et al. · Addiction Neuroscience · 2026

From the methods
Mice were allowed 5 min to explore an elevated zero maze (Maze Engineers, Skokie, IL) and their movements were recorded from above and analyzed with Anymaze (Wood Dale, IL).
Periaqueductal gray neurotensin neurons drive simultaneous threat response and reinforcement

Grace O. Davis, Siyi Ma, McKenna Kernan et al. · Preprint on bioRxiv · 2026

From the methods
Mice were placed into the into the elevated zero maze arena (Maze Engineers, 50 cm diameter, 5 cm track width) under low light conditions (4-6 lumens).
Butyrate preserves entorhinal-hippocampal spatial coding and blood brain barrier integrity in mice with depleted gut microbiome

Joshua M. Glynn, Joshua J. Strohl, Ciara Bagnall-Moreau et al. · Preprint on bioRxiv · 2025

From the methods
The zero maze apparatus (Maze Engineers, Skokie, IL, USA) consisted of a circular maze with 4 quadrants of alternating open and closed segments.
Serotonin as a biomarker of toxin-induced Parkinsonism

Anna Marie Buchanan, Sergio Mena, Iman Choukari et al. · Molecular Medicine · 2024

From the methods
Mice were placed into the closed section of the maze (Maze Engineers, Boston, MA, USA) and were allowed to explore for 5 min.
Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice

Aya Osman, Nicholas L. Mervosh, Ana N. Strat et al. · Brain, Behavior, and Immunity · 2023

From the methods
To further assess anxiety-like behavior, mice were placed in the center of an open arm of an elevated zero maze (Maze Engineers) and allowed to move freely for 5 minutes.
Central and Peripheral Nervous System Sequelae Following Blast Exposures: A Multi-Organ System Analysis of a Complex Full-Body Injury

Britahny M. Baskin · Thesis at University of Washington · 2023

From the methods
Elevated zero maze (EZM): Animals were allowed to explore an elevated zero maze (Maze Engineers, Skokie, IL) for 5 min.
Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice

Samantha Pavlock, Deirdre M. McCarthy, Anisha Kesarwani et al. · International Journal of Neuroscience · 2023

From the methods
Anxiety-like behavior was assessed using the elevated zero maze (EZM; Maze Engineers, Boston, MA).
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior

Dajin Cho, Kyle O'Berry, Ingrid Camila Possa-Paranhos et al. · The Journal of Neuroscience · 2023

From the methods
Before the start of the elevated zero maze test (EZM; MazeEngineers) mice were allowed 30 min to acclimate to the new environment of the behavioral testing room.
Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury

Britahny M. Baskin, Aric F. Logsdon, Suhjung Janet Lee et al. · Brain, Behavior, and Immunity · 2023

From the methods
Animals were allowed to explore an elevated zero maze (Maze Engineers, Skokie, IL) for 5 min.
A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice

Melinda Hersey, Melissa Reneaux, Shane N. Berger et al. · Journal of Neuroinflammation · 2022

From the methods
Each mouse was placed into the closed section of the apparatus (Maze Engineers, Boston, MA, USA) and allowed to explore for 5 min.
Aconitum Alkaloid Songorine Exerts Potent Gamma-Aminobutyric Acid-A Receptor Agonist Action In Vivo and Effectively Decreases Anxiety without Adverse Sedative or Psychomotor Effects in the Rat

Zsolt Kristóf Bali, Nóra Bruszt, Zsombor Kőszegi et al. · Pharmaceutics · 2022

From the methods
The EOM apparatus (Maze Engineers, Glenview, IL, USA) consisted of a circular platform placed on 61 cm tall stands.
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

Sara K. Jones, Deirdre M. McCarthy, Cynthia Vied et al. · Proceedings of the National Academy of Sciences · 2022

From the methods
...elevated maze consisting of continuous alternating open and closed areas arranged in a circle (Maze Engineers, Boston, MA).