Research data · Disease model and test
Light-dark box in epilepsy and seizures research
From 2021 to 2025, 32 animal research papers on epilepsy and seizures mentioned the light-dark box in their title or abstract.
That is 2.0 times the 16 papers of 2011 to 2015. Between the same two periods, the papers on epilepsy and seizures that mention any of the 90 tests we count grew more slowly, to 1.3 times as many.
Papers by year
Animal research papers on epilepsy and seizures that mention the light-dark box, by year, 2001 to 2026
The 2026 bar counts papers added to PubMed by November 8, 2026.
- Papers in a full year
- 2026 so far
Show the counts for each year
| Year | Papers |
|---|---|
| 2001 | 0 |
| 2002 | 4 |
| 2003 | 2 |
| 2004 | 0 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 0 |
| 2008 | 1 |
| 2009 | 4 |
| 2010 | 4 |
| 2011 | 6 |
| 2012 | 2 |
| 2013 | 3 |
| 2014 | 3 |
| 2015 | 2 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 7 |
| 2019 | 7 |
| 2020 | 6 |
| 2021 | 5 |
| 2022 | 8 |
| 2023 | 4 |
| 2024 | 9 |
| 2025 | 6 |
| 2026 (part year) | 2 |
Papers on epilepsy and seizures that mention the light-dark box fell from 5 in 2021 to 4 in 2023, then rose to 6 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.
Which species the papers used
Each bar is a share of the 32 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.
Species
“Other animals” counts papers that use none of the species this chart names.
Tests mentioned alongside the light-dark box
Each bar is one test, with how many of the 32 papers also mention it, and what share that is. Of these papers, 9 (28%) mention no other test.
The 12 tests these papers mention most
Which papers count
A paper counts here when it is animal research, mentions the light-dark box in its title or abstract, and studies epilepsy and seizures.
We tell whether a paper studies epilepsy and seizures from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.
The page on epilepsy and seizures research names the subject headings we count as epilepsy and seizures. Download the test list for the search terms we used for the light-dark box, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.
More tests and disease models
Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.
Papers on epilepsy and seizures that mention other tests
Papers on other disease models that mention the light-dark box
The page on the light-dark box counts all the papers that mention it, whatever they study. The page on epilepsy and seizures research ranks the tests by their papers on epilepsy and seizures.
How to cite
APA
ConductScience. (2026, November 10). Light-dark box in epilepsy and seizures research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/epilepsy/light-dark-box
BibTeX
@misc{conductscience_epilepsy_light_dark_box_2026,
author = {{ConductScience}},
title = {Light-dark box in epilepsy and seizures research},
year = {2026},
month = nov,
url = {https://conductscience.com/resources/data/behavioral-tests/models/epilepsy/light-dark-box},
note = {Data set, released November 10, 2026},
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