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Light-dark box in psychological stress research

From 2021 to 2025, 58 animal research papers on psychological stress mentioned the light-dark box in their title or abstract.

That is 1.1 times the 51 papers of 2011 to 2015. Between the same two periods, the papers on psychological stress that mention any of the 90 tests we count fell 10%.

58 papers on psychological stress from 2021 to 2025 mentioned the light-dark box
4% of the papers on psychological stress that mention any test mention the light-dark box
8% of the papers that mention the light-dark box are on psychological stress
1.1 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on psychological stress that mention the light-dark box, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20014
20023
20033
20042
20057
20064
20076
20085
20096
201014
20119
201211
20138
201412
201511
201617
201710
201814
201913
202018
202113
20228
202314
202410
202513
2026 (part year)15

Papers on psychological stress that mention the light-dark box fell from 13 in 2021 to 8 in 2022, then rose to 13 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 58 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
30 papers 52%
Rat
24 papers 41%
Zebrafish
4 papers 7%
Fruit fly
1 paper 2%

Tests mentioned alongside the light-dark box

Each bar is one test, with how many of the 58 papers also mention it, and what share that is. Of these papers, 5 (9%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions the light-dark box in its title or abstract, and studies psychological stress.

We tell whether a paper studies psychological stress from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on psychological stress research names the subject headings we count as psychological stress. Download the test list for the search terms we used for the light-dark box, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on the light-dark box counts all the papers that mention it, whatever they study. The page on psychological stress research ranks the tests by their papers on psychological stress.

How to cite

APA

ConductScience. (2026, November 10). Light-dark box in psychological stress research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/stress/light-dark-box

BibTeX

@misc{conductscience_stress_light_dark_box_2026,
  author = {{ConductScience}},
  title = {Light-dark box in psychological stress research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/behavioral-tests/models/stress/light-dark-box},
  note = {Data set, released November 10, 2026},
}

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