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Elevated plus maze in schizophrenia and psychosis research

From 2021 to 2025, 36 animal research papers on schizophrenia and psychosis mentioned the elevated plus maze in their title or abstract.

That is 1.9 times the 19 papers of 2011 to 2015. Between the same two periods, the papers on schizophrenia and psychosis that mention any of the 90 tests we count fell 9%.

36 papers on schizophrenia and psychosis from 2021 to 2025 mentioned the elevated plus maze
9% of the papers on schizophrenia and psychosis that mention any test mention the elevated plus maze
1% of the papers that mention the elevated plus maze are on schizophrenia and psychosis
1.9 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on schizophrenia and psychosis that mention the elevated plus maze, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20010
20020
20032
20040
20051
20061
20071
20087
20091
20104
20115
20123
20133
20143
20155
20163
201715
20184
20197
20203
20218
20229
20236
20245
20258
2026 (part year)4

Papers on schizophrenia and psychosis that mention the elevated plus maze fell from 8 in 2021 to 5 in 2024, then rose to 8 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 36 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
19 papers 53%
Rat
18 papers 50%

Tests mentioned alongside the elevated plus maze

Each bar is one test, with how many of the 36 papers also mention it, and what share that is. Of these papers, 6 (17%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions the elevated plus maze in its title or abstract, and studies schizophrenia and psychosis.

We tell whether a paper studies schizophrenia and psychosis from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on schizophrenia and psychosis research names the subject headings we count as schizophrenia and psychosis. Download the test list for the search terms we used for the elevated plus maze, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on the elevated plus maze counts all the papers that mention it, whatever they study. The page on schizophrenia and psychosis research ranks the tests by their papers on schizophrenia and psychosis.

How to cite

APA

ConductScience. (2026, November 10). Elevated plus maze in schizophrenia and psychosis research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/schizophrenia/elevated-plus-maze

BibTeX

@misc{conductscience_schizophrenia_elevated_plus_maze_2026,
  author = {{ConductScience}},
  title = {Elevated plus maze in schizophrenia and psychosis research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/behavioral-tests/models/schizophrenia/elevated-plus-maze},
  note = {Data set, released November 10, 2026},
}

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