Research data ยท Brain technique and test

Operant conditioning with optogenetics

From 2021 to 2025, 41 animal research papers mentioned optogenetics and operant conditioning in their title or abstract.

That is 2.4 times the 17 papers of 2011 to 2015. Between the same two periods, the papers that mention optogenetics and any of the 90 tests we count grew faster, to 4.0 times as many.

41 animal research papers from 2021 to 2025 mentioned optogenetics and operant conditioning
9% of the 443 papers from 2021 to 2025 that mention optogenetics and a test mention operant conditioning
4% of the 945 papers from 2021 to 2025 that mention operant conditioning also mention optogenetics
2.4 times as many papers as in 2011 to 2015

Papers by year

Animal research papers that mention optogenetics and operant conditioning, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20010
20020
20030
20040
20050
20060
20070
20080
20090
20100
20111
20122
20135
20144
20155
20167
201711
20185
201910
202013
202111
20226
202313
20245
20256
2026 (part year)6

Papers that mention optogenetics and operant conditioning fell from 11 in 2021 to 5 in 2024, then rose to 6 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. We take a paper's species from PubMed's indexing when the indexing names one. Otherwise PubTator 3, NCBI's text-mining service, has to find a species in the title or abstract, or the paper is not counted. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 41 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
25 papers 61%
Rat
15 papers 37%
Fruit fly
2 papers 5%

Tests mentioned alongside operant conditioning

Each bar is one test, with how many of the 41 papers also mention it, and what share that is. Of these papers, 28 (68%) mention no other test.

The 8 tests these papers mention most

Real-time place preference
2 papers 5%
1 paper 2%

Which papers count

A paper counts here when it is animal research and its title or abstract mentions optogenetics and operant conditioning.

A paper that mentions either only in its methods is missed, so the count runs low. The search terms are in the list of models and techniques and the test list. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More pairings

Every pairing of a brain technique and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on operant conditioning counts all the papers that mention it, whatever they study. The page on optogenetics ranks the tests mentioned with it.

How to cite

APA

ConductScience. (2026, November 13). Operant conditioning with optogenetics [Data set]. https://conductscience.com/resources/data/brain-techniques/optogenetics/operant-conditioning

BibTeX

@misc{conductscience_optogenetics_operant_conditioning_2026,
  author = {{ConductScience}},
  title = {Operant conditioning with optogenetics},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/brain-techniques/optogenetics/operant-conditioning},
  note = {Data set, released November 13, 2026},
}

Operant conditioning apparatus in our store

In the test battery tool, pick every test your study will run and add the apparatus we sell for them to one quote.