Research data · Attention and executive function

Puzzle box

From 2021 to 2025, 34 animal research papers mentioned the puzzle box in their title or abstract, ranking it 71st of the 90 tests we track.

It had 6 papers in 2011 to 2015, too few to compare.

34 animal research papers from 2021 to 2025 mentioned the test
6 papers in 2011 to 2015, too few to compare
71st of the 90 tests by papers from 2021 to 2025
50% of these papers used other animals

Papers by year

Animal research papers that mention the puzzle box, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20010
20020
20030
20040
20054
20061
20070
20080
20090
20102
20111
20121
20131
20142
20151
20165
20173
20185
20194
20207
20215
20228
20237
20246
20258
2026 (part year)5

Which species the papers used

Each bar is a share of the 34 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Other animals
17 papers 50%
Mouse
15 papers 44%
Rat
1 paper 3%
Nonhuman primate
1 paper 3%

“Other animals” counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 28 of the 34 papers, so each bar is a share of those 28.

C57BL mice
8 papers 29%
Transgenic mice
1 paper 4%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention the puzzle box and study that disease model, with its share of the 34 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

1 paper 3%
1 paper 3%
1 paper 3%
Down syndrome
1 paper 3%

Tests mentioned alongside the puzzle box

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 34 papers that mention the puzzle box.

Papers from 2021 to 2025 that mention both tests

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention the puzzle box and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits.

    Theranostics, 2021. 99 citations.

  2. HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity.

    Theranostics, 2022. 42 citations.

  3. Bumblebees socially learn behaviour too complex to innovate alone.

    Nature, 2024. 26 citations.

  4. Bumblebees acquire alternative puzzle-box solutions via social learning.

    PLoS Biol, 2023. 20 citations.

  5. The effect of urbanization on innovation in spotted hyenas.

    Anim Cogn, 2021. 18 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions the puzzle box only in its methods is missed, so the count runs low. The count includes 1 review. For 6 of the 34 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More attention and executive function tests

These attention and executive function tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Puzzle box in published research [Data set]. https://conductscience.com/data/behavioral-tests/puzzle-box

BibTeX

@misc{conductscience_puzzle_box_2026,
  author = {{ConductScience}},
  title = {Puzzle box in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/puzzle-box},
  note = {Data set, released November 10, 2026},
}

Apparatus for the puzzle box

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