Research data ยท Motor function and endurance

Rotarod

From 2021 to 2025, 1,844 animal research papers mentioned the rotarod in their title or abstract, ranking it ninth of the 90 tests we track.

That is 1.4 times the 1,317 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

1,844 animal research papers from 2021 to 2025 mentioned the test
1.4 times as many papers as in 2011 to 2015
9th of the 90 tests by papers from 2021 to 2025
67% of these papers used mice and 36% used rats

Papers by year

Animal research papers that mention the rotarod, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200180
200280
2003101
2004105
2005120
2006110
2007134
2008155
2009157
2010196
2011215
2012263
2013270
2014273
2015296
2016305
2017311
2018337
2019330
2020360
2021358
2022352
2023303
2024380
2025451
2026 (part year)429

Papers that mention the rotarod fell from 358 in 2021 to 303 in 2023, then rose to 451 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's species from PubMed's indexing whenever it names one, so part of this dip may come from the indexing rather than from fewer studies.

Mice led rats every year from 2001 to 2025.

Papers that mention the rotarod in mice and in rats, by year, 2001 to 2025

  • Mouse
  • Rat
Show the counts for each year and species
Papers by year, mice and rats
YearMouseRat
20015041
20025237
20037046
20047048
20058151
20067047
20079745
200810555
200910564
201013177
2011121106
201218789
201318594
2014185100
2015203104
2016203123
2017193128
2018228129
2019236107
2020246128
2021243128
2022228128
2023198111
2024247136
2025311154

Which species the papers used

Each bar is a share of the 1,844 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
1,227 papers 67%
Rat
657 papers 36%
Other animals
25 papers 1%
Zebrafish
5 papers under 1%
Nonhuman primate
2 papers under 1%
Fruit fly
1 paper under 1%

โ€œOther animalsโ€ counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 1,474 of the 1,844 papers, so each bar is a share of those 1,474.

C57BL mice
446 papers 30%
Sprague-Dawley rats
188 papers 13%
Wistar rats
160 papers 11%
Transgenic mice
110 papers 7%
Knockout mice
77 papers 5%
BALB/c mice
26 papers 2%
ICR mice
14 papers 1%
mdx mice
10 papers 1%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention the rotarod and study that disease model, with its share of the 1,844 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

Tests mentioned alongside the rotarod

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 1,844 papers that mention the rotarod.

Papers from 2021 to 2025 that mention both tests

283 papers 15%
192 papers 10%
191 papers 10%
141 papers 8%
123 papers 7%
98 papers 5%
95 papers 5%

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention the rotarod and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis.

    J Neuroinflammation, 2022. 217 citations.

  2. Targeting ROS-Dependent AKT/GSK-3ฮฒ/NF-ฮบB and DJ-1/Nrf2 Pathways by Dapagliflozin Attenuates Neuronal Injury and Motor Dysfunction in Rotenone-Induced Parkinson's Disease Rat Model.

    ACS Chem Neurosci, 2021. 156 citations.

  3. Quercetin Protects against MPP+/MPTP-Induced Dopaminergic Neuron Death in Parkinson's Disease by Inhibiting Ferroptosis.

    Oxid Med Cell Longev, 2022. 136 citations.

  4. TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage.

    J Neuroinflammation, 2021. 116 citations.

  5. Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways.

    Biochem Pharmacol, 2021. 116 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions the rotarod only in its methods is missed, so the count runs low. The count includes 19 reviews. For 371 of the 1,844 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More motor function and endurance tests

These motor function and endurance tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Rotarod in published research [Data set]. https://conductscience.com/data/behavioral-tests/rotarod

BibTeX

@misc{conductscience_rotarod_2026,
  author = {{ConductScience}},
  title = {Rotarod in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/rotarod},
  note = {Data set, released November 10, 2026},
}

Apparatus for the rotarod

Our store sells one product for the rotarod.

Shop the apparatus

Papers that name our apparatus

We keep our own list of published papers whose text names our equipment. Those that mention the rotarod in the title or abstract are already in the counts above.