Industrial Continuous Flow Glass Microreactor

The Industrial Continuous Flow Glass Microreactor scales continuous-flow synthesis to pilot and production volumes, for APIs and related synthesis. Each module combines one process plate with two heat-exchange plates, and modules combine freely to suit the process. Microchannels give a large surface area per volume, so mass and heat transfer are fast, reactions run safely in small volumes, and conditions scale with little change from lab to pilot.

The process side resists all reagents except 30% KOH, molten alkali metals and HF. Typical uses are pharmaceutical intermediates and synthesis, fine and specialty chemicals, pesticide chemistry, nanomaterials and polymer modification, with reactions such as Michael additions, Friedel–Crafts alkylations, aldol reactions, sulfonation, nitration, diazotization and azidation.

Specifications

• Throughput: 50–150 t per year
• Module: one process plate and two heat-exchange plates
• Reactor plates: B270 glass, 6–7 mL holdup each
• Recommended configuration: 8–12 modules
• Temperature: −25 to 195 °C
• Pressure: 0–20 bar