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SpectrophotometerLab Basics

Spectrophotometer

The spectrophotometer is a common optical device that measures the intensity of light relative to color (or wavelength). In the lab, they are used to determine how much light is absorbed by a colored chemical dissolved in solution. This allows us to calculate the concentration or purity of chemicals, analyze…
September 19, 2019
Weight Drop Injury ModelProtocols

Weight Drop Injury Model

Traumatic brain injury (TBI) is one of the most common brain injuries caused by an external impact or pressure, such as rapid acceleration or deceleration, crushing, and projectile penetration. Following TBI, cognitive, physical, and psychosocial functions are impaired depending on the severity of the injury. To investigate TBI, several animal…
September 14, 2019
6-OHDA rat modelsProtocolsScience

6-OHDA rat models

Parkinson’s disease (PD) is the most common neurological disorder that is characterized by debilitating motor abnormalities, including muscle rigidity, resting tumor, stiffer voluntary movements, and postural instability. Primary neuropathological condition of PD includes progressive degeneration of the dopaminergic neurons in the nigrostriatal area. Experimental models of PD are specifically designed…
September 13, 2019
Animal Models of Traumatic Brain InjuryProtocolsScience

Animal Models of Traumatic Brain Injury

The use of animal models for studying traumatic brain injury (TBI) has several advantages, including low breeding cost, easy maintenance, and innovative techniques to create genetically modified strains. Rodent models provide powerful tools to screen and characterize putative therapeutic targets in TBI. These models efficiently recapitulate several clinical features of…
September 13, 2019
Rodent Craniotomy ProtocolProtocolsScience

Rodent Craniotomy Protocol

A craniotomy is a surgical procedure used to temporarily open a part of the skull to expose the brain for experimental manipulations. Research developments over the past two decades have made craniotomy safer, simpler, and more successful. In craniotomy, a bone flap is removed from the skull to reach the…
September 13, 2019
Controlled Cortical Impact for Traumatic Brain InjuryProtocols

Controlled Cortical Impact for Traumatic Brain Injury

Traumatic brain injury (TBI) is referred to as alteration or dysfunctionality in brain function, or brain pathology resulted by external trauma or force. TBI is a serious health condition because of its complexity and wide-reaching effects, including lesions, necrosis, and axon degeneration. Research on traumatic brain injury has been challenging…
September 13, 2019