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Nucleic Acid Quantification ProtocolsLaboratory TechniquesScience

The Spiral Structure of Chromosome

A Chromosome is an organized package of DNA, located inside the nucleus. The structure of a chromosome involves six essential parts, that include: Pellicle and matrix, chromonemata, chromomere, centromere, secondary constriction, and satellite body. So, chromonemata are the spiral structures that are embedded in the matrix of the chromosome and…
October 12, 2020
SDS-Polyacrylamide Gel Electrophoresis at Neutral pH (NuPAGE)Laboratory TechniquesProtocolsScience

Cellulose Acetate Electrophoresis

Cellulose acetate electrophoresis is a type of zone electrophoresis that separates molecules in liquid form such as proteins on a membrane or stripe made of cellulose acetate. Developed by a German chemist, Joachim Kohn (1912-1987) in 1957, cellulose acetate electrophoresis was the second form of zone electrophoresis, after filter paper…
October 9, 2020
CytologyLaboratory TechniquesScience

The Cytogenetics of Fungi

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Fungi is a group of eukaryotic organisms that include a myriad of single and multicellular organisms that are parasitic or saprophytic in nature. Over 1.5 million species of fungus have been discovered and they are found in a range…
October 2, 2020
Nucleic Acid Quantification ProtocolsLaboratory Techniques

Human Sex Chromosomes and X-inactivation

Chromosomes are thread-like structures, located in the nucleus, which carry hereditary information in the form of genes. Structurally, it is composed of ā€˜packaging proteins and DNA moleculesā€™, and it is represented in different shapes and numbers which vary among different living organisms. For example, bacteria have circular chromosomes, whereas organisms…
September 28, 2020
tRNA MutationsConductLab BasicsScience

sgRNA construction and design

Clustered regularly interspaced short palindromic repeats (CRISPR) technology is a rapid, cheap, and efficient tool to edit genomes at a precise location. CRISPR technology has now been reduced to just two components: Endonuclease and g RNA. Endonuclease makes an incision at the target DNA molecule to be edited, and gRNA…
September 22, 2020

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