Research data · Disease model and test

Fear conditioning in substance use disorders research

From 2021 to 2025, 31 animal research papers on substance use disorders mentioned fear conditioning in their title or abstract.

That is 6% fewer than the 33 papers of 2011 to 2015. Between the same two periods, the papers on substance use disorders that mention any of the 90 tests we count fell 12%. The 2021 to 2025 count may run low because of a dip in PubMed's indexing, explained under the year chart.

31 papers on substance use disorders from 2021 to 2025 mentioned fear conditioning
2% of the papers on substance use disorders that mention any test mention fear conditioning
2% of the papers that mention fear conditioning are on substance use disorders
6% fewer papers than in 2011 to 2015

Papers by year

Animal research papers on substance use disorders that mention fear conditioning, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20015
20021
20036
20043
20053
20065
20074
20089
20096
20107
20117
20127
20137
20146
20156
20169
201711
20186
201910
20208
20219
20224
20235
20247
20256
2026 (part year)12

Papers on substance use disorders that mention fear conditioning fell from 9 in 2021 to 4 in 2022, then rose to 6 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 31 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
17 papers 55%
Rat
13 papers 42%
Other animals
1 paper 3%

“Other animals” counts papers that use none of the species this chart names.

Tests mentioned alongside fear conditioning

Each bar is one test, with how many of the 31 papers also mention it, and what share that is. Of these papers, 11 (35%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions fear conditioning in its title or abstract, and studies substance use disorders.

We tell whether a paper studies substance use disorders from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on substance use disorders research names the subject headings we count as substance use disorders. Download the test list for the search terms we used for fear conditioning, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on fear conditioning counts all the papers that mention it, whatever they study. The page on substance use disorders research ranks the tests by their papers on substance use disorders.

How to cite

APA

ConductScience. (2026, November 10). Fear conditioning in substance use disorders research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/substance-use/fear-conditioning

BibTeX

@misc{conductscience_substance_use_fear_conditioning_2026,
  author = {{ConductScience}},
  title = {Fear conditioning in substance use disorders research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/behavioral-tests/models/substance-use/fear-conditioning},
  note = {Data set, released November 10, 2026},
}

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