Research data · Disease model and test

Operant conditioning in substance use disorders research

From 2021 to 2025, 178 animal research papers on substance use disorders mentioned operant conditioning in their title or abstract.

That is 31% fewer than the 259 papers of 2011 to 2015. Between the same two periods, the papers on substance use disorders that mention any of the 90 tests we count fell 12%. The 2021 to 2025 count may run low because of a dip in PubMed's indexing, explained under the year chart.

178 papers on substance use disorders from 2021 to 2025 mentioned operant conditioning
11% of the papers on substance use disorders that mention any test mention operant conditioning
19% of the papers that mention operant conditioning are on substance use disorders
31% fewer papers than in 2011 to 2015

Papers by year

Animal research papers on substance use disorders that mention operant conditioning, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200137
200240
200340
200440
200538
200642
200754
200855
200958
201044
201143
201257
201352
201459
201548
201654
201758
201859
201943
202051
202149
202238
202324
202434
202533
2026 (part year)33

Papers on substance use disorders that mention operant conditioning fell from 49 in 2021 to 24 in 2023, then rose to 33 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 178 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Rat
124 papers 70%
Mouse
52 papers 29%
Nonhuman primate
4 papers 2%
Other animals
4 papers 2%

“Other animals” counts papers that use none of the species this chart names.

Tests mentioned alongside operant conditioning

Each bar is one test, with how many of the 178 papers also mention it, and what share that is. Of these papers, 53 (30%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions operant conditioning in its title or abstract, and studies substance use disorders.

We tell whether a paper studies substance use disorders from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on substance use disorders research names the subject headings we count as substance use disorders. Download the test list for the search terms we used for operant conditioning, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on operant conditioning counts all the papers that mention it, whatever they study. The page on substance use disorders research ranks the tests by their papers on substance use disorders.

How to cite

APA

ConductScience. (2026, November 10). Operant conditioning in substance use disorders research [Data set]. https://conductscience.com/resources/data/behavioral-tests/models/substance-use/operant-conditioning

BibTeX

@misc{conductscience_substance_use_operant_conditioning_2026,
  author = {{ConductScience}},
  title = {Operant conditioning in substance use disorders research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/resources/data/behavioral-tests/models/substance-use/operant-conditioning},
  note = {Data set, released November 10, 2026},
}

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