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NIH funding notice PA-20-188

NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

Closed on May 7, 2024.

Posted
May 5, 2020
Close date
May 7, 2024
Activity codes
K99, R00
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAMS, NIAID, NIBIB, NCCIH, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NINDS, NINR, NLM, ORIP, NIMHD

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-19-130 NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed)
  2. 2 steps back: PA-18-398 NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed)
  3. 3 steps back: PA-16-193 NIH Pathway to Independence Award (Parent K99/R00)
  4. 4 steps back: PA-16-077 NIH Pathway to Independence Award (Parent K99/R00)
  5. 5 steps back: PA-15-083 NIH Pathway to Independence Award (Parent K99/R00)
  6. 6 steps back: PA-14-042 NIH Pathway to Independence Award (Parent K99/R00)
  7. 7 steps back: PA-11-197 NIH Pathway to Independence Award (Parent K99/R00)
  8. 8 steps back: PA-10-063 NIH Pathway to Independence Award (Parent K99/R00)
  9. 9 steps back: PA-09-036 NIH Pathway to Independence Award (K99/R00)
  10. 10 steps back: PA-07-297 NIH Pathway to Independence (PI) Award (K99/R00)
  11. 11 steps back: PA-06-133

Replaced by PA-24-194.

Who won it before

2,814 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $325,377,584 in first-year total cost, median $113,949.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I]357
  2. NST-2 Study Section [NST-2]155
  3. NHLBI Mentored Transition to Independence Study Section[MTI (JA)]103
  4. Career Development Facilitating The Transition to Independence Study Section[AGCD-1]98
  5. NHLBI Mentored Transition to Independence Study Section[MTI (MA)]95

Most frequent institutions

  1. STANFORD UNIVERSITY222
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO118
  3. MASSACHUSETTS GENERAL HOSPITAL97
  4. COLUMBIA UNIVERSITY HEALTH SCIENCES81
  5. UNIVERSITY OF WASHINGTON68
Competing awards under PA-20-188 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025The effect of aging on cDC1 function and CD8 T cell immunity in tumors1K99CA296769-01CHEN, CHANG-YU ALEXMASSACHUSETTS GENERAL HOSPITAL, MA$176,040NCI
2025Midbrain opioid circuit dynamics in pain and endogenous analgesia1K99DA060979-01KIMMEY, BLAKEUNIVERSITY OF PENNSYLVANIA, PA$173,799NIDA
2025Retinal circuit integration and degeneration in Neurofibromatosis type-11K99EY036954-01YOUNG, BRENT KEVINSTANFORD UNIVERSITY, CA$172,818ZEY1
2025The Role of Histone Cleavage in Breast Cancer1K99CA297044-01LI, ZHEQIDANA-FARBER CANCER INST, MA$170,640NCI
2025Integration of novel contextual and genomic blood pressure measures to enhance cardiovascular disease prediction and management in young adults1K99HL177340-01CHO, SO MIBROAD INSTITUTE, INC., MA$165,364MTI
2025IL-27 functions as a novel signal 3 cytokine and promotes cytotoxic T cell responses to tumors1K99CA290077-01A1LAFLEUR, MARTINHARVARD MEDICAL SCHOOL, MA$163,296NCI
2025Genomic Conflict Resolution: Establishment of a new model for unconstrained germline selection1K99HG014014-01BIEGLER, MATTHEW THEODORROCKEFELLER UNIVERSITY, NY$158,509GNOM
2025Metabolically Reprogramming Hepatic Macrophages to Conquer Immune Desert Tumors1K99CA297030-01JI, LIANGLIANGSLOAN-KETTERING INST CAN RESEARCH, NY$145,336NCI
2025Genetic dependencies in KIAA1549-BRAF rearranged pediatric low-grade gliomas1K99CA290163-01A1MISEK, SEAN ALEXANDERBROAD INSTITUTE, INC., MA$143,788NCI
2025Elucidating Thiol Reductive Stress in Lung Cancer Growth and Metastasis1K99CA296772-01GE, MAOLINMASSACHUSETTS GENERAL HOSPITAL, MA$140,130NCI
2025Data-driven mechanistic models of morphology-controlled Ras oncogenic signaling1K99CA283246-01A1MAZLOOM FARSIBAF, HANIEHUT SOUTHWESTERN MEDICAL CENTER, TX$140,097NCI
2025Integrating Genetics and Socio-Environmental Factors to Predict Disease Progression1K99HG013969-01WANG, YINGMASSACHUSETTS GENERAL HOSPITAL, MA$138,499GNOM
2025Subtyping tinnitus based on fMRI dynamic functional connectivity1K99DC022305-01HAKONEN, MARIAMASSACHUSETTS GENERAL HOSPITAL, MA$134,730CDRC
2025Structural and Functional Alteration of host RBCs by Babesia1K99AI182422-01A1BERI, DIVYANEW YORK BLOOD CENTER, NY$134,730MID
2025A calvarial stem cell mediating a new bone-brain axis in Alzheimer's disease1K99AG090732-01BOK, SEOYEONWEILL MEDICAL COLL OF CORNELL UNIV, NY$134,325AGCD
2025Discerning L-type trafficking modulation by targeted excision of ubiquitin and SUMO1K99HL177343-01SHANMUGAM, SRI KARTHIKACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$133,436MTI
2025T cell surveillance of senescent cells under homeostasis and aging1K99AG090620-01STURMLECHNER, INESMAYO CLINIC ROCHESTER, MN$133,353AGCD
2025Role of TLR7/8-activating microRNAs in fetal inflammatory response syndrome1K99HD116981-01GEORGES, HANAH MYALE UNIVERSITY, CT$132,779CHHD
2025Targeting Metabolic Vulnerabilities to Restore Balanced Hematopoiesis during Aging1K99AG086600-01A1GHELLER, BRANDONBOSTON CHILDREN'S HOSPITAL, MA$132,705AGCD
2025Regulating host neural activity to improve retinal ganglion cell replacement therapies1K99EY036122-01A1SOUCY, JONATHAN RSCHEPENS EYE RESEARCH INSTITUTE, MA$132,597ZEY1
2025Apoptotic Dysregulation Across Cell Types in Aging and Neurodegeneration1K99AG086405-01A1INDE, ZINTISUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$132,472AGCD
2025Understanding the Nature and Regulation of Extramedullary Hematopoiesis in the Liver1K99HL173841-01A1GAO, LONGFEICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$130,337MTI
2025Regulating Skeletal Stem Cell and Neutrophil Dynamics for Improved Cleft Palate Bone Regeneration by Newly Designed Surrogate Bone Morphogenetic Protein-21K99DE032773-01A1TAKEMATSU, ERISTANFORD UNIVERSITY, CA$129,420DSR
2025Comprehensive monitoring of diverse cancer outcomes using genomic and epigenomic sequencing of cfDNA1K99CA290092-01A1LI, SHUOUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$128,509NCI
2025Environmental mixtures, immune function, and vaccine antibody response in children1K99ES036168-01A1HE, MIKE ZHONGYUICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$126,985ZES1
2025Generation of new neurons in the aging adult brain: identifying mechanisms of adult neurogenesis by exploiting single cell spatial transcriptomics.1K99AG090813-01MAIMON, ROYUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$126,956AGCD
2025Deciphering Determinants of Somatic Evolution with Single-Cell Genealogy1K99HG013991-01WENG, CHENBOSTON CHILDREN'S HOSPITAL, MA$126,830GNOM
2025Identifying Ecological Drivers of Dysbiosis in the Female Reproductive Tract1K99AI187628-01RADLINSKI, LAUREN CHRISTINEUNIVERSITY OF CALIFORNIA AT DAVIS, CA$126,460MID
2025Neural population geometry and dynamics underlying multi-step cognitive-motor sequencing1K99NS140554-01VYAS, SAURABHCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$126,333NST
2025High-Throughput Studies of MYH7 Variant Cardiomyocytes to Identify Pathogenic Variants and Factors Governing Variable Expressivity of Hypertrophic Cardiomyopathy1K99HL177347-01FRIEDMAN, CLAYTON EUNIVERSITY OF WASHINGTON, WA$126,306MTI
2025Functional role of Wnt/Ca2+ signaling in triple-negative breast cancer metastasis and chemoresistance1K99CA290088-01A1SI, HONGJIANGBAYLOR COLLEGE OF MEDICINE, TX$125,834NCI
2025Impacts of non-antibiotic medications on microbiome-mediated protection against intestinal pathogens1K99AI187630-01KUMAR, AMANYALE UNIVERSITY, CT$125,809MID
2025Mechanisms of CDH1-inactivated advanced gastric adenocarcinoma tumorigenesis1K99CA286745-01A1ZOU, GENGYIUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$125,783NCI
2025Epigenetic modulations by sleep to mitigate neurodegeneration1K99AG090693-01PARHIZKAR, SAMIRAWASHINGTON UNIVERSITY, MO$125,000AGCD
2025Role of Protein N-Myristoylation in Driving DNA Damage Response1K99GM157498-01LUONG, NHO CONGEMORY UNIVERSITY, GA$125,000ZGM1
2025Towards a structural understanding of transcriptional regulation by ZMYM2-KDM1A-CoREST1K99GM154065-01A1WACHTER, FRANZISKADANA-FARBER CANCER INST, MA$125,000ZGM1
2025Combinatorial signal integration in the maintenance and renewal of adult germline stem cell fate1K99GM154143-01A1RAZ, AMELIEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$125,000ZGM1
2025Probing the Rules of Protein Structure-Function Relationships through the De Novo Design of Functional Proteins1K99GM157551-01SCHNAIDER, LEEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$124,767ZGM1
2025Development of Highly Multiplexed Raman Imaging Platform for Alzheimer’s Disease1K99EB035706-01A1EREMINA, OLGA E.UNIVERSITY OF SOUTHERN CALIFORNIA, CA$124,562ZEB1
2025Fused Imaging and Large Language Foundational Model for 90-day Stroke Outcome Prediction1K99NS140547-01LIU, YONGKAISTANFORD UNIVERSITY, CA$124,485NST
2025Advanced Base and Prime Editing Strategies to Correct Common ALS-causing SOD1 Mutations1K99NS136849-01A1MEIJBOOM, KATHARINA EUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$124,246NST
2025Coordinated mental simulation in the hippocampus and primary visual cortex during active behavior1K99EY036953-01LEE, KYU HYUNUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$124,205ZEY1
2025Novel role of ROCK2 in Immune Mechanisms of Takotsubo Cardiomyopathy1K99HL177309-01FEHRENBACH, DANIEL JINDIANA UNIVERSITY INDIANAPOLIS, IN$123,930MTI
2025Reversing the Irreversible: Reshaping Plant Growth upon Recovery from Severe Stress1K99GM154136-01A1ELIAZ, NATANELLASALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$123,795ZGM1
2025Neuronal mechanisms of selective visual attention1K99EY036889-01FRIGHETTO, GIOVANNIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$123,794ZEY1
2025The role of Gasdermin D in the bone marrow microenvironment during clonal hematopoiesis progression1K99CA289959-01A1REN, KEHANNORTHWESTERN UNIVERSITY, IL$123,409NCI
2025Molecular profiles for mortality risk and longevity: a multiomics approach1K99AG086538-01A1WANG, FENGLEIHARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, MA$122,858AGCD
2025Macrophage identity as a function of cell of origin1K99AI187733-01FRENIS, KATIEBOSTON CHILDREN'S HOSPITAL, MA$122,839AITC
2025A Prospective Study of Per-and Polyfluoroalkyl Substance (PFAS) Mixtures and Pregnancy Outcomes among Black Women1K99ES036288-01A1SCHILDROTH, SAMANTHABOSTON UNIVERSITY MEDICAL CAMPUS, MA$121,057ZES1
2025Identifying transcriptomic axes governing neural dynamics, behavior, and states1K99MH138830-01SEO, CHANGWOOHARVARD UNIVERSITY, MA$120,015ZMH1
2025Role of gestational hypoxia in maternal brain health1K99HD115156-01A1BRADSHAW, JESSICA LYNNEUNIVERSITY OF NORTH TEXAS HLTH SCI CTR, TX$117,226CHHD
2025Country-Specific Modeling of Verbal Autopsy Misclassification for Improved Child and Neonatal Cause-Specific Mortality Estimates at Low- and High-Resolution Causes1K99HD114884-01A1PRAMANIK, SANDIPANJOHNS HOPKINS UNIVERSITY, MD$115,585CHHD
2025Elucidating a novel respiratory-mammary axis of T cell immunity1K99AI182458-01A1ARMISTEAD, BLAIRSEATTLE CHILDREN'S HOSPITAL, WA$114,976AITC
2025Characterizing determinants of cellular senescence and epigenetic dysregulation on tobacco smoke exposure in lung1K99HL171851-01A1KAUR, GAGANDEEPUNIVERSITY OF ROCHESTER, NY$113,683MTI
2025Basal Ganglia Network Neurophysiology of Depression in Parkinson’s Disease1K99NS137249-01A1JOHNSON, KARA ANNUNIVERSITY OF FLORIDA, FL$112,158NST
2025The role of oral microbiota in metastatic brain tumors1K99CA296780-01MORAD, GOLNAZUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$112,026NCI
2025Targeting Macrophage Populations to Attenuate Pulmonary Hypertension Associated with Sickle Cell Disease1K99HL177608-01LISK, CHRISTINAUNIVERSITY OF COLORADO DENVER, CO$111,626MTI
2025Quality control and spatial regulation of bacterial condensates1K99GM157383-01HOANG, YUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$109,255ZGM1
2025Structural and Functional Characterization of CELSR-subfamily adhesion G protein-coupled receptors1K99GM157487-01BANDEKAR, SUMITUNIVERSITY OF CHICAGO, IL$108,793ZGM1
2025Early Changes of T2* Measures in Lung Tissues using deltaTE-UTE MRI on healthy and COPD Patients1K99HL177415-01MALIS, VADIMUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$108,003ZHL1
2025Differential sorting and trafficking of Plasmodium falciparum secreted proteins.1K99AI187629-01HASAN, MD MAHMUDULWASHINGTON UNIVERSITY, MO$107,542MID
2025The joint effects of early life lead exposure, and psychosocial co-exposures, on physiological stress and cardiometabolic health across the life course1K99ES036294-01A1HALABICKY, OLIVIA MARYFRANCESUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$107,493ZES1
2025Mechanisms of Double Strand Break Repair in Fetal Male Germ Cells1K99HD117011-01HATKEVICH, TALIA LEEDUKE UNIVERSITY, NC$107,458CHHD
2025Structured quantification of inherited macular disease phenotypes as the basis for automated algorithms to determine causal genes1K99EY036930-01LEE, WINSTONCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$105,516ZEY1
2025Systematic dissection of viral genetic interactions and mutations with COEXPRES-Seq1K99AI182471-01A1LIN, AARON ERICPRINCETON UNIVERSITY, NJ$101,142MID
2025GABAPVp-originated neural circuits mediate metabolic benefits during cold exposure1K99DK139407-01A1LIU, HAILANBAYLOR COLLEGE OF MEDICINE, TX$91,500DDK
2025Regulation of intestinal lipid metabolism by type-3 immune cytokine1K99DK138289-01A1GAO, YAJINGUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$91,073DDK
2025Integration of dietary factors and multi-omic signatures of genetic subtypes to understand diabetes heterogeneity1K99DK139461-01A1SEVILLA GONZALEZ, MAGDALENAMASSACHUSETTS GENERAL HOSPITAL, MA$90,000DDK
2025Noninvasive assessment of renal fibrosis in kidney transplant recipients bymulti-contrast magnetic resonance imaging1K99DK138294-01A1STABINSKA, JULIAHUGO W. MOSER RES INST KENNEDY KRIEGER, MD$90,000DDK
2025Adverse gut microbiome promotes resistance immune checkpoint inhibitors via chronic inflammation1K99CA296940-01BARUCH, EREZ NUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$32,400NCI
2025Alcohol-Induced Metabolome-Epigenome Dysfunction and Alzheimer’s Disease Risk1K99AA032034-01BALASUBRAMANIAN, NAGALAKSHMIUNIVERSITY OF IOWA, IA$7,784AA
2024Scaling-up Medication for Opioid Use Disorder in Residential Treatment Settings1K99DA057372-01A1MILES, JENNIFERRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$217,879NIDA
2024Using Mobile Technology to Examine Mechanisms Linking Sleep and Smoking Cessation1K99DA058711-01A1RA, CHAELIN KARENRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$211,211NIDA
2024Parvalbumin Interneuron Regulation of a Prelimbic to Ventrolateral Periaqueductal Gray Pathway for Modulating Pain Following Adolescent Intermittent Ethanol Exposure1K99AA031717-01OBRAY, JAMES DANIELMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$194,551AA
2024Neurobiological mechanisms underlying changes in PTSD-like symptoms after cannabis use1K99DA058761-01A1HODEBOURG, RITCHYMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$187,152NIDA
2024The influence of astroglial mu opioid receptors in opioid potentiation of HIV neuropathogenesis1K99DA059324-01NASS, SARAVIRGINIA COMMONWEALTH UNIVERSITY, VA$187,151NIDA
2024Using EMA to Examine Minority Stress Mechanisms Underlying Cannabis Use among Sexual Minorities1K99DA057994-01A1PARNES, JAMIEEMMA PENDLETON BRADLEY HOSPITAL, RI$182,498NIDA
2024Non-alcoholic beverages: A foundational assessment of their potential utility in reducing alcohol use1K99AA031716-01BOWDRING, MOLLYSTANFORD UNIVERSITY, CA$178,805AA
2024Postpartum Neurobiological Sequelae of Prescription Opioid Use During Pregnancy1K99DA060209-01LUJAN PEREZ, MIGUEL ANGELUNIVERSITY OF MARYLAND BALTIMORE, MD$178,322NIDA
2024Endocannabinoid modulation of behavioral engagement via an aPVT-NAc circuit1K99DA059617-01MARCUS, DAVID J.UNIVERSITY OF WASHINGTON, WA$174,625NIDA
2024Investigation into the function of hypothalamic GABA and glutamate in motivation for opioid reward1K99DA059612-01A1GORDON-FENNELL, ADAM GUNIVERSITY OF WASHINGTON, WA$173,167ZDA1
2024Dissecting FOSL1-mediated lineage plasticity and resistance to androgen receptor signaling inhibition in prostate cancer1K99CA286721-01WONG, CHEN KHUANSLOAN-KETTERING INST CAN RESEARCH, NY$173,016NCI
2024Uncovering the Impact of Innate Immunity on Transfusion Medicine Immunobiology1K99HL169746-01A1WU, SHANG-CHUENBRIGHAM AND WOMEN'S HOSPITAL, MA$172,800MTI
2024Programmable biohybrid system for cancer therapy1K99CA283259-01A1HAHN, JAESEUNGCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$172,044NCI
2024Multi-omic investigation of the adiposity-lipid intersection and its role in cardiovascular disease risk1K99HL175031-01DRON, JACQUELINE SHIRLEYMASSACHUSETTS GENERAL HOSPITAL, MA$171,450MTI
2024Functions and Mechanisms of Lung Microfold cells during Invasive Pneumococcal Disease1K99HL171884-01A1SURVE, MANALEE VMASSACHUSETTS GENERAL HOSPITAL, MA$171,450MTI
2024Learning features of optimal CAR T cells for LBCL from patient data1K99CA293149-01GOOD, ZINAIDASTANFORD UNIVERSITY, CA$171,072NCI
2024Mechanotransduction regulation of cellular metabolism in pulmonary fibrosis1K99HL169903-01A1THOMAS FREEBERG, MARGARETVIRGINIA COMMONWEALTH UNIVERSITY, VA$170,543MTI
2024Using Single-cell and Spatial Multi-omics to Improve Adoptive Cell Therapy against Pancreatic Cancer1K99CA293142-01SU, YAPENGFRED HUTCHINSON CANCER CENTER, WA$169,344NCI
2024Functional and molecular characterization of the central amygdala in the context of oxycodone withdrawal1K99DA056691-01A1SLIVICKI, RICHARDWASHINGTON UNIVERSITY, MO$165,911NIDA
2024The role of proteoglycans in Heparin-induced thrombocytopenia: Implications for pathophysiology, diagnosis and treatment1K99HL171911-01KANACK, ADAM JMAYO CLINIC ROCHESTER, MN$165,780MTI
2024Discovering and Characterizing Druggable Cysteines in Cancer Dependency Proteins1K99CA290143-01LI, HAOXINSCRIPPS RESEARCH INSTITUTE, THE, CA$165,780NCI
2024Dissecting spatiotemporal heterogeneity of glioblastoma evolution under therapy1K99CA286730-01MIGLIOZZI, SIMONAUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$163,402NCI
2024Differentiation of Microbe-microbe Interactions at Single-cell Level Through Unconventional Utilization of Expansion Microscopy1K99DE033794-01DONG, PU-TINGADA FORSYTH INSTITUTE, INC., MA$162,216DSR
2024Mesenchymal cell plasticity and signaling in lung regeneration1K99HL173656-01JONES, DAKOTA LUNIVERSITY OF PENNSYLVANIA, PA$156,665MTI
2024Molecular control of stochastic color vision circuit assembly1K99EY035757-01CHEN, YU-CHIEHNEW YORK UNIVERSITY, NY$154,332ZEY1
2024The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer1K99CA286742-01JANG, HYO SIKVAN ANDEL RESEARCH INSTITUTE, MI$153,160NCI
2024Frontiers at the edge: Subpleural fibroblasts orchestrate pulmonary fibrosis progression1K99HL171830-01XU, LEUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$153,130MTI
2024Rare Airway Cell Function in Post-Viral Chronic Inflammation1K99HL169897-01A1BARR, JUSTINNUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$152,212MTI
2024PATHFINDER: Finding the genomic and clinical pathways underlying heterogeneity in complex disease1K99HG013547-01GARCIA GONZALEZ, JUDITICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$151,956ZHG1
2024Unraveling the Role of p53 in Endothelium Homeostasis after Ionizing Radiation Exposure1K99HL173685-01JAHNG, WON SUKSTANFORD UNIVERSITY, CA$149,948MTI
2024Scalable methods to quantify epileptic network and guide epilepsy surgery1K99NS138680-01SINHA, NISHANTUNIVERSITY OF PENNSYLVANIA, PA$148,956NST
2024Targeting Pancreatic Cancer Senescence with ImmunoPET1K99CA276804-01A1PRATT, EDWIN CHARLESSLOAN-KETTERING INST CAN RESEARCH, NY$148,282NCI
2024Novel gene regulatory networks underlying two specialized modes of craniofacial development in a new model system of pupfishes1K99DE034058-01PALOMINOS CHACON, MARIA FERNANDAUNIVERSITY OF CALIFORNIA BERKELEY, CA$148,176DSR
2024Associations between structural stigma and alcohol use among sexual minority women and their offspring1K99AA031316-01A1MCKETTA, SARAH CLAIBOURNEHARVARD PILGRIM HEALTH CARE, INC., MA$147,165AA
2024Mechanisms of mGlu1 regulation of cortical inhibition and cognitive function: Implications in adolescent cocaine exposure1K99DA058712-01A1LUESSEN, DEBORAH JOYCEVANDERBILT UNIVERSITY, TN$144,235NIDA
2024Increasing Diversity of the Genomics Workforce Through Accessible Data and Visualization1K99HG013348-01A1LYI, SEHIHARVARD MEDICAL SCHOOL, MA$144,087GNOM
2024Reprogramming T cell function with multiplexed genome engineering to develop next-generation immunotherapy1K99CA282989-01A1ZHOU, XIAOYUYALE UNIVERSITY, CT$142,502NCI
2024Enabling mRNA Therapies for Pediatric High-Grade Gliomas1K99NS138490-01YERNENI, SAIGOPALAKRISHNAMAYO CLINIC ROCHESTER, MN$142,452NST
2024Deciphering the role of mitochondrial metabolism in liver cancer1K99CA286722-01UNLU, GOKHANROCKEFELLER UNIVERSITY, NY$142,066NCI
2024Computational Modeling of the Interplay between External Signaling and Transcription Rewiring using Spatial Transcriptomics and Single Cell Multiome Data1K99HG013429-01CHU, TIN YIYALE UNIVERSITY, CT$142,065GNOM
2024Sphingosine kinase 1 plays a key role in defective elastin-induced arterial hypermuscularization1K99HL171838-01SAITO, JUNICHIYALE UNIVERSITY, CT$139,579MTI
2024The crosstalk between obesity-induced fatty liver and liver metastasis1K99CA283664-01A1ZHU, CHANGYUSLOAN-KETTERING INST CAN RESEARCH, NY$139,125NCI
2024Defining novel mechanisms of microbiota in regulating anti-tumor responses1K99CA290052-01LYU, MENGZEWEILL MEDICAL COLL OF CORNELL UNIV, NY$138,240NCI
2024Understanding barriers and facilitators to pharmacogenomic testing in chronic pain care1K99HG013600-01HENDY, KATHERINE MARIEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$137,218ZRG1
2024Understanding fertility trends in a cohesive high-fertility population within a low-fertility environment1K99HD111665-01A1ANDERSON, CORYPENNSYLVANIA STATE UNIVERSITY, THE, PA$137,160CHHD
2024Exploring PAR2 Trafficking in Oral Cancer: Implications for Pain Signaling and Drug Delivery1K99DE033792-01A1RAMIREZ GARCIA, PAULINA DANIELANEW YORK UNIVERSITY, NY$137,050DSR
2024Studying Protein Affinity to DNA by in vitro Transcription and Sequencing (PADIT-seq)1K99HG013675-01KHETAN, SHUBHAMBRIGHAM AND WOMEN'S HOSPITAL, MA$136,661GNOM
2024Investigating Afferent Baroreflex Dysfunction in Hypertension1K99HL175100-01EL SAAFIEN, KHALIDGEORGIA STATE UNIVERSITY, GA$136,350ZHL1
2024Elucidating Neighborhood- and Individual-Level Factors Associated with Pregnancy Glycemia Levels and Childhood Obesity1K99HD115836-01CHEHAB, RANA F.KAISER FOUNDATION RESEARCH INSTITUTE, CA$136,350CHHD
2024Ribonucleoprotein complexes involved in the late phase of HIV-1 replication1K99AI186598-01HOLLMANN, NELE MERRETUNIVERSITY OF MARYLAND BALTIMORE COUNTY, MD$136,350AIDS
2024Uncovering the Mechanisms that Promote and Maintain Germ Cell Identity1K99HD113821-01GRILL, SHERILYN ANNWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$135,864CHHD
2024The world’s smallest vertebrate brain: A new model for nervous system function and regeneration research1K99HD115278-01ATABAY, KUTAY DENIZWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$135,864CHHD
2024A multiscale computational and experimental platform to investigate cardiomyopathies and targeted therapeutics1K99HL173646-01CHILDERS, MATTHEW CARTERUNIVERSITY OF WASHINGTON, WA$135,840MTI
2024Developing a communication support intervention for cancer caregivers in emerging and young adulthood1K99CA279651-01A1KASTRINOS, AMANDASLOAN-KETTERING INST CAN RESEARCH, NY$135,224NCI
2024The uncharacterized nuclear protein HMGXB4 in occlusive vascular diseases1K99HL171834-01A1HE, XIANGQINAUGUSTA UNIVERSITY, GA$135,000MTI
2024Adolescent Friendship Networks: Effects on Immigrant Youth’s Psychosocial Health1K99HD114887-01KHUU, THOAPENNSYLVANIA STATE UNIVERSITY, THE, PA$134,938CHHD
2024Prediction of dementia in older adults using nonlinear EEG features1K99AG083234-01A1HAGHAYEGH, SHAHABMASSACHUSETTS GENERAL HOSPITAL, MA$134,730AGCD
2024Menopause, hormone therapy and Alzheimer's disease clinicopathology: An in vivo perspective1K99AG083063-01A1COUGHLAN, GILLIAN THERESAMASSACHUSETTS GENERAL HOSPITAL, MA$134,730AGCD
2024Deciphering the role of pH regulator Slc4a4 in glioma progression1K99CA295327-01A1YE, QIBAYLOR COLLEGE OF MEDICINE, TX$134,582NCI
2024Metasurface Optical Guidewire for percutaneous coronary intervention (PCI)1K99HL173631-01KATTA, NITESHUNIVERSITY OF CALIFORNIA-IRVINE, CA$134,151MTI
2024Role of PGM-3 and SPE-56 in fertilization and egg activation1K99HD115785-01MANIATES, KATHERINE ANNRUTGERS, THE STATE UNIV OF N.J., NJ$133,207CHHD
2024Toward unshielded MRI for improved safety and access1K99EB035647-01KAZEMIVALIPOUR, EHSANMASSACHUSETTS GENERAL HOSPITAL, MA$133,176ZEB1
2024Bridging stochastic and deterministic paradigm of olfactory receptor choice in ants1K99DC021991-01SIERIEBRIENNIKOV, BOGDANNEW YORK UNIVERSITY, NY$133,110CDRC
2024Behavioral and neural measures of phonological-to-orthographic transfer in young children1K99HD113838-01A1ISBILEN, ERINYALE UNIVERSITY, CT$132,867CHHD
2024Holographic activation of ensemble activity during sleep in a mouse model of Alzheimer's disease1K99AG084853-01LINES, JUSTINICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$132,705AGCD
2024Endothelial regulation of the blood-placental barrier1K99HL175038-01GAO, SIQIUNIVERSITY OF PENNSYLVANIA, PA$132,705MTI
2024Neural Markers of Developmental Delays in Premature and Full Term Infants1K99HD115830-01KELSEY, CAROLINE M.BOSTON CHILDREN'S HOSPITAL, MA$132,705CHHD
2024Taste perception of host cues in the invasive disease vector mosquito Aedes albopictus1K99DC021504-01BAIK, LISA SOYEONYALE UNIVERSITY, CT$132,543CDRC
2024Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohort1K99AG084769-01KEZIOS, KATRINA LCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$131,733AGCD
2024Rest/Active Phase Specificity of APOE4 and Inflammation on Respiratory Plasticity1K99HL175029-01MARCIANTE, ALEXANDRIAUNIVERSITY OF FLORIDA, FL$131,733MTI
2024Sexual orientation-related disparities in unintended pregnancies by state-level policy and structural contexts1K99HD114852-01CHAKRABORTY, PAYALHARVARD PILGRIM HEALTH CARE, INC., MA$131,657CHHD
2024Integrative models of nuclear DNA organization1K99HG013663-01JHA, ANUPAMAUNIVERSITY OF WASHINGTON, WA$131,338GNOM
2024Emotional and biobehavioral mechanisms of parent-infant emotional synchrony1K99HD115784-01LAVALLEE, ANDREANECOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$131,333CHHD
2024Bridging the gap between genetic variants and radiomic phenotypes via genomic large language models1K99HG013661-01LIU, QIAOSTANFORD UNIVERSITY, CA$131,085GNOM
2024Endometrial immune microenvironment dysfunction in endometriosis pathobiology1K99HD115829-01FEYAERTS, DORIENSTANFORD UNIVERSITY, CA$131,085CHHD
2024Probing and engineering the B cell response to the skin microbiota1K99AI180358-01A1BOUSBAINE, DJENETSTANFORD UNIVERSITY, CA$131,085AITC
2024Targeting Perp in PDAC tumor and cancer cachexia1K99CA283277-01A1DASGUPTA, ANEESHAINDIANA UNIVERSITY INDIANAPOLIS, IN$131,072NCI
2024Studying Neuronal Proteostasis During Aging and AD with Novel Protein Tagging Tools1K99AG088304-01GULDNER, IAN HUNTERSTANFORD UNIVERSITY, CA$131,027AGCD
2024The Role of Reproductive Aging for Racial Differences in AD/ADRD from Midlife to Older Age1K99AG084897-01A1REEVES, ALEXISSTANFORD UNIVERSITY, CA$131,004AGCD
2024Early Events in Extravillous Trophoblast Cell Differentiation1K99HD115834-01MORENO, AYELENUNIVERSITY OF KANSAS MEDICAL CENTER, KS$130,680CHHD
2024The Role of Distinct Dorsal Column Nuclei Outputs in Persistent Pain1K99NS133476-01A1GRADWELL, MARKRUTGERS, THE STATE UNIV OF N.J., NJ$130,610NST
2024Single cell multi-omics approaches in identifying driving cells and genes in pediatric MODS patients requiring ECMO support1K99HD111575-01A1SHANKAR, RAMAHENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI$130,584CHHD
2024C-type natriuretic peptide in hypertrophic cardiomyopathy1K99HL171847-01ARMSTRONG, DAVID WILLIAM JOHNVANDERBILT UNIVERSITY MEDICAL CENTER, TN$130,518MTI
2024Engineering viral nanoparticles for TLR agonist-based multi-functional cancer immunotherapies1K99CA283299-01A1ZHAO, ZHONGCHAOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$130,350NCI
2024Semi-supervised cross-modality translation for single-cell genomics and proteomics1K99HG013343-01A1ZHANG, RANUNIVERSITY OF WASHINGTON, WA$129,723GNOM
2024Whole chromosome fine-mapping integrating diverse ancestries for psychiatric disorders1K99MH135172-01A1YUAN, KAIMASSACHUSETTS GENERAL HOSPITAL, MA$129,288ZMH1
2024Novel Diurnal Model for In Vitro Fertilization Studies1K99HD113843-01A1YAW, ALEXANDRA MARIEMICHIGAN STATE UNIVERSITY, MI$129,205CHHD
2024How myelin regulates vestibular circuit function and balance behaviors1K99DC021729-01AUER, FRANZISKANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$129,168CDRC
2024Analyzing the roles of social class and power dynamics in health disparities over the life course1K99AG081545-01A1EISENBERG-GUYOT, JERZYNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$129,115AGCD
2024Esophageal squamous cell cancer initiation and immune landscape remodeling1K99CA286761-01A1KO, KYUNG PILUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$128,936NCI
2024A CRISPR-based toolkit for investigating hair cell transcription factors in inner ear organoids1K99DC021984-01MATERN, MAGGIE S.STANFORD UNIVERSITY, CA$128,922CDRC
2024Genetic and genomic influences on human milk composition and impacts on infant health1K99HD113834-01JOHNSON, KELSEY ELIZABETHUNIVERSITY OF MINNESOTA, MN$128,817CHHD
2024Targeting mitochondrial vulnerabilities to drive intrinsic melanoma immunogenicity1K99CA283154-01A1LIANG, JIAXINDANA-FARBER CANCER INST, MA$128,798NCI
2024Identifying Hidden Relational Processes that Fragment Care for Older Adults with ADRD and Multimorbidity: A Social Network Analysis Approach1K99AG083213-01A1WEI, SIJIANORTHWESTERN UNIVERSITY AT CHICAGO, IL$128,548AGCD
2024Mapping the cosmetic chemical exposome and its role in female fertility1K99ES036289-01YOUNG, ANNA SWIFTEMORY UNIVERSITY, GA$128,358ZES1
2024Cell surface protein dynamics in neural circuit assembly1K99DC021195-01MCLAUGHLIN, COLLEENSTANFORD UNIVERSITY, CA$128,331CDRC
2024Contribution of hypocretin neuron activity to Alzheimer's related sleep disturbances1K99AG086609-01GONZALEZ, OSCAR CHRISTIANSTANFORD UNIVERSITY, CA$128,331AGCD
2024Examination of the Role of Executive Function during Reading and Math in Children1K99HD111574-01A1MARTINEZ-LINCOLN, AMANDAVANDERBILT UNIVERSITY, TN$128,250CHHD
2024Neuro-immune regulation of inter-organ skin-gut inflammation1K99AI180354-01A1YANO, HIROSHIWEILL MEDICAL COLL OF CORNELL UNIV, NY$128,250AITC
2024Dissection of specialized metabolism in plants using multiplexed perturbation1K99AT012787-01MCCLUNE, CONOR JAMESSTANFORD UNIVERSITY, CA$128,046ZAT1
2024Next-generation photoacoustic imaging for real-time, non-invasive monitoring of brain oxygen metabolism1K99EB035645-01ZHANG, YIDECALIFORNIA INSTITUTE OF TECHNOLOGY, CA$127,465ZEB1
2024Development of Distinct Areas in the Human Cerebral Cortex1K99NS135123-01QIAN, XUYUBOSTON CHILDREN'S HOSPITAL, MA$127,305NST
2024Genomic approaches to understand human neural specializations1K99MH136290-01SONG, JANETBOSTON CHILDREN'S HOSPITAL, MA$127,305ZMH1
2024Neural Mechanisms and Neuromodulation of Affective States1K99MH137315-01FOLLONI, DAVIDEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$127,305ZMH1
2024Deciphering the intrinsic myocardial and/or endocardial defects of hypoplastic left heart syndrome1K99HL169927-01A1HUANG, MENGMENGBOSTON CHILDREN'S HOSPITAL, MA$127,278MTI
2024Functional genomics approaches to decode the roles of transcription factor isoforms1K99HG013345-01MATTIOLI, KAIABRIGHAM AND WOMEN'S HOSPITAL, MA$127,170GNOM
2024The Urban Environment as a Modifiable Social Determinant of Health among People with HIV1K99AI181608-01A1ZALLA, LAUREN C.JOHNS HOPKINS UNIVERSITY, MD$126,387AIDS
2024Identifying sources of variation in microbiome-pathogen dynamics during Clostridioides difficile colonization1K99AI175674-01A1FISHBEIN, SKYE REBECCAWASHINGTON UNIVERSITY, MO$126,333MID
2024Spinal Direct Current Stimulation to Enhance Breathing Following Cervical Spinal Cord Injury1K99NS133388-01A1RANA, SABHYAUNIVERSITY OF FLORIDA, FL$126,333NST
2024The Role of Functional Modularity in the Neural Code Underlying Contextual Behavior1K99NS138578-01JOHNSTON, WILLIAM JCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$126,333NST
2024Examining the Implementation and Impact of School Resource Officer Policy Reform in the United States1K99HD112509-01A1HULLENAAR, KEITHUNIVERSITY OF WASHINGTON, WA$126,306CHHD
2024Neurodevelopmental adaptations prime olfactory circuits for complex pheromonal communication in the clonal raider ant.1K99DC021506-01FRANK, DOMINIC DAVIDROCKEFELLER UNIVERSITY, NY$125,902CDRC
2024Genetic and single-cell multi-omic characterization of Alzheimer's disease risk and resilience pathways1K99AG086583-01D'OLIVEIRA ALBANUS, RICARDOWASHINGTON UNIVERSITY, MO$125,896AGCD
2024Epigenetic and genetic regulation of arsenic methylation and arsenic-relatedcardiovascular disease risk1K99ES035109-01A1BOZACK, ANNE KRISTINASTANFORD UNIVERSITY, CA$125,847ZES1
2024Dissecting distinct contributions of different Prefrontal subregions on goal-directed visual attention1K99EY035752-01A1AEHRLUND RICHTER, SOFIEMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$125,734ZEY1
2024Human stem cell derived forebrain model to study persistent neurotoxic effects of trans-placental developmental exposures to environmental pollutants1K99ES036290-01TUKKER, ANKE MARIJEPURDUE UNIVERSITY, IN$125,694ZES1
2024Transcriptional regulation of oligodendroglial differentiation1K99NS135117-01A1ROJO CAPITANIO, DANIELASTANFORD UNIVERSITY, CA$125,685NST
2024Novel role of Foxc2 in regulating metabolic disease1K99HL171947-01CUI, KUIBOSTON CHILDREN'S HOSPITAL, MA$125,658MTI
2024Unraveling Fatty Acid-driven Mechanisms of Platelet Hyper-Activation in Obesity1K99HL175037-01BARRACHINA, MARIA N.BOSTON CHILDREN'S HOSPITAL, MA$125,658MTI
2024WNK1-dependent macropinocytosis mediates emergency myelopoiesis1K99HL171844-01A1TRZECIAK, ALISSA JANESLOAN-KETTERING INST CAN RESEARCH, NY$125,431MTI
2024Harnessing Wolbachia-induced conditional infertility for control of the malaria mosquito1K99AI185151-01ADAMS, KELSEY LEANNEHARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, MA$125,250MID
2024Validation and Kinetic Characterization of Blood-Cerebrospinal Fluid Barrier-Traversing Proteins in Aging With Library-Free Multiplexed Targeted Proteomics1K99AG088297-01SHUKEN, STEVEN ROBERTHARVARD MEDICAL SCHOOL, MA$125,172AGCD
2024Regulation of exon junction complex composition and assembly1K99GM152790-01ABSHIRE, ELIZABETH TENLEYUNIVERSITY OF ROCHESTER, NY$125,000ZGM1
2024Visualizing transcription factor binding and chromatin assembly on newly synthesized DNA1K99GM152821-01WOOTEN, MATTHEWFRED HUTCHINSON CANCER CENTER, WA$125,000ZGM1
2024Understanding how transposons generate new immune gene protein-coding splice variants1K99GM152820-01PASQUESI, GIULIA IRENE MARIAUNIVERSITY OF COLORADO, CO$125,000ZGM1
2024Molecular regulation of double-strand break repair by MDC11K99GM149942-01A1HEYZA, JOSHUAHENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI$125,000ZGM1
2024Mechanistic Interrogation of Long Non-coding RNAs using Photocatalytic Proximity Labeling and CRISPR Phenotypic Profiling1K99GM154140-01KNUTSON, STEVEN DOUGLASPRINCETON UNIVERSITY, NJ$125,000ZGM1
2024Functional Convergence at the Host-Virus Interface1K99GM155323-01BOYS, IANUNIVERSITY OF UTAH, UT$125,000ZGM1
2024The Molecular Basis of PIEZO Ion Channel Function1K99GM155547-01MULHALL, ERIC MICHAELSCRIPPS RESEARCH INSTITUTE, THE, CA$125,000ZGM1

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