Recovery Time
Duration from seizure onset to resumption of normal locomotion, the primary endpoint for bang-sensitive mutant screening
ConductVision · Behavioral Analysis
Drosophila Bang Sensitivity
Quantify seizure susceptibility and recovery from mechanical shock in Drosophila.
DrosophilaSeizure / NeurologicalAuto Export
ConductVision / Drosophila Bang Sensitivity
Recording / Trial 3fly tracked
Recovery28s
Seizure12.5s
BS Index0.65
Key Parameters
Metrics automatically extracted by ConductVision.
Seizure Duration
Length of the convulsive episode (leg-shaking, wing-buzzing) following 10-second mechanical vortex stimulation
Bang Sensitivity Index
Composite score integrating paralysis duration, seizure severity, and recovery speed into a single 0–1 metric
Paralysis Latency
Time from vortex onset to first observable seizure behavior, indicating seizure threshold and circuit excitability
Percent Paralyzed
Fraction of flies displaying seizure or paralysis at 5-second intervals post-vortex, generating population kinetics
Recovery Curve
Time-course plot of behavioral recovery across the cohort fitted to a sigmoid, yielding T50 and slope parameters
+ 4 more parameters trackedShow allHide
Seizure Phase Classification
Automated labeling of initial paralysis, tonic phase, clonic phase, and recovery using locomotor activity state transitions
Wing Buzz Duration
Total time spent in high-frequency wing vibration during the seizure episode, a hallmark of clonic seizure phase
Post-Recovery Activity
Locomotor activity level in the 5 minutes after seizure recovery, measuring post-ictal depression or hyperactivity
Repeat Stimulation Response
Change in seizure severity and recovery time across consecutive vortex trials, assessing seizure kindling or resistance
What is the Bang Sensitivity Assay?
The bang sensitivity assay measures seizure susceptibility in Drosophila. Mechanical stimulation (10-second vortex) induces stereotyped seizure-like behavior in susceptible mutants: initial paralysis, followed by leg-shaking, wing-buzzing, and gradual recovery. The assay is used to identify seizure-suppressor and seizure-enhancer genes relevant to human epilepsy.
ConductVision automates post-vortex tracking, classifying paralysis, seizure, and recovery phases from locomotor activity patterns. The software outputs recovery time, paralysis fraction, and seizure duration for high-throughput genetic and pharmacological screening of antiepileptic compounds.
Compatible Equipment
Related paradigms
Continue with drosophila analysis
DrosophilaSensory Integration
Drosophila Visual & Olfactory Apparatus
Combined visual and olfactory sensory integration assessment.
DrosophilaLocomotor Behavior
Drosophila Maze Array
Interchangeable maze geometries for spatial cognition and turn bias analysis.
DrosophilaSpatial Learning
Heat Maze
Spatial learning via aversive heat conditioning in Drosophila.
DrosophilaSocial Behavior
Drosophila Shallow Chamber
Monolayer confinement for precise locomotor and social behavior tracking.
DrosophilaMotor Function
Drosophila Negative Geotaxis
Automated scoring of climbing ability and motor performance in Drosophila.
DrosophilaReproductive Behavior
Drosophila Courtship Assay
Automated quantification of courtship ritual behaviors and mating success.
Ready to automate your behavioral analysis?
Request a demo or contact our team to discuss how ConductVision can accelerate your research.
