High-Pressure Microfluidic Syringe Pump
Single-channel high-pressure syringe pump with 0.09 μL/min to 124.36 mL/min flow range and RS-485 interface for precise microfluidic applications.
Louise Corscadden, PhD
Neuroscience · ConductScience
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The High-Pressure Microfluidic Syringe Pump delivers precise fluid control for demanding microfluidic applications requiring elevated pressure capabilities. This single-channel pump accommodates syringes from 2.5 to 100 mL and provides flow rates spanning from 0.09 μL/min to 124.36 mL/min, enabling both ultra-low volume delivery and higher throughput applications.
The system features dual control interfaces including a digital knob with membrane controls for manual operation and RS-485 communication for automated integration. The high-pressure capability makes it suitable for applications involving viscous fluids, high backpressure microfluidic devices, or systems requiring precise pressure-driven flow control in research environments.
How It Works
The syringe pump operates through precise stepper motor-driven linear displacement of the syringe plunger. The motor advances or retracts the plunger at controlled rates, creating positive displacement flow that is independent of backpressure variations within the pump's operating range. This mechanical principle ensures accurate volumetric delivery regardless of fluid viscosity or downstream resistance.
The high-pressure capability is achieved through robust mechanical construction and motor torque specifications that can overcome elevated backpressures common in microfluidic devices with narrow channels or restrictive geometries. The RS-485 interface enables digital control of flow parameters and integration with automated systems, while the digital knob provides direct manual control for setup and operation.
Features & Benefits
Channels
- 1
Syringe Range
- 2.5 - 100 mL
Flow Rate
- 0.09 uL/min - 124.36 mL/min
Features
- High-pressure capability
Interface
- Digital knob + membrane, RS-485
Automation Level
- semi-automated
Brand
- ConductScience
Research Domain
- Analytical Chemistry
- Cell Biology
- Environmental Monitoring
- Materials Science
- Microbiology
- Pharmaceutical QC
Weight
- 6.3 kg
Dimensions
- L: 280.0 mm
- W: 250.0 mm
- H: 140.0 mm
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Flow Rate Range | 0.09 μL/min - 124.36 mL/min | Entry-level pumps often provide narrower ranges or higher minimum flow rates | Enables both precise low-volume delivery and higher throughput applications with one instrument |
| Pressure Capability | High-pressure rated design | Standard pumps may lack high-pressure specifications | Maintains flow accuracy even with restrictive microfluidic devices or viscous fluids |
| Syringe Compatibility | 2.5 - 100 mL range | Limited compatibility ranges common in compact pumps | Accommodates various experiment durations and volumes without frequent syringe changes |
| Control Interface | Digital knob + RS-485 communication | Basic models often provide only manual or only digital control | Supports both hands-on operation and automated system integration |
| Single Channel Design | Dedicated single channel | Multi-channel systems add complexity for simple applications | Provides focused control and eliminates cross-contamination risks for single-line applications |
This pump combines wide flow rate capability with high-pressure operation and flexible control interfaces. The single-channel design offers dedicated precision for individual microfluidic applications while accommodating various syringe sizes for different experimental requirements.
Practical Tips
Verify flow rate accuracy periodically by measuring actual delivered volume over a timed interval using a precision balance.
Why: Mechanical wear and temperature variations can affect flow accuracy over time.
Clean fluid pathways with appropriate solvents after each use and store with the syringe empty to prevent contamination.
Why: Residual fluids can crystalize or react, leading to blockages or contamination in subsequent experiments.
Prime the system at 10-20% of target flow rate to eliminate air bubbles before starting precision delivery protocols.
Why: Air bubbles cause flow irregularities and can compress under high pressure, affecting delivery accuracy.
If flow becomes irregular, check for loose tubing connections and verify the syringe is properly seated in the holder.
Why: Mechanical looseness introduces compliance in the system that degrades volumetric accuracy.
Allow the pump to reach steady-state flow before beginning measurements, especially at very low flow rates.
Why: Flow stabilization time increases at lower rates due to system compliance and fluid dynamics.
When working with high-pressure applications, use proper tubing rated for the system's pressure capabilities and inspect connections regularly.
Why: High pressure can cause catastrophic failure of undersized components, leading to sample loss and safety hazards.
Match syringe size to experiment duration to minimize refilling interruptions while avoiding unnecessary dead volume.
Why: Larger syringes reduce refilling frequency but increase fluid waste and dead volume in the system.
Setup Guide
What’s in the Box
- High-Pressure Microfluidic Syringe Pump main unit
- Power adapter (typical)
- RS-485 communication cable (typical)
- Syringe mounting hardware (typical)
- User manual and software documentation (typical)
- Calibration certificate (typical)
Warranty
ConductScience provides a standard one-year manufacturer warranty covering defects in materials and workmanship, with technical support available for setup and operational guidance.
Compliance
What is the maximum backpressure this pump can overcome?
Consult the product datasheet for specific maximum operating pressure ratings, as this varies with syringe size and flow rate settings.
Can I use glass syringes with this pump?
The pump accommodates syringes from 2.5 to 100 mL capacity; compatibility with glass syringes depends on the mounting mechanism design details in the specifications.
What accuracy can I expect at low flow rates?
Flow accuracy specifications should be verified in the product datasheet, particularly for ultra-low flow rates near the 0.09 μL/min minimum.
How do I integrate this pump with my existing automation system?
The RS-485 interface provides digital communication capability; consult the technical documentation for protocol specifications and command sets.
What maintenance is required for consistent performance?
Regular cleaning of fluid paths, periodic calibration verification, and replacement of seals or O-rings as specified in the maintenance schedule.
Can this pump handle organic solvents?
Chemical compatibility depends on wetted materials construction; verify solvent compatibility in the chemical resistance chart provided with specifications.
What is the minimum stable flow rate achievable?
The specified minimum is 0.09 μL/min, though practical stability may depend on syringe size, tubing compliance, and system backpressure.
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