Research data · Brain technique
Microdialysis
From 2021 to 2025, 133 animal research papers mentioned microdialysis and at least one behavioral test.
That is 52% fewer than the 279 papers of 2011 to 2015. Between the same two periods, all the animal research papers that mention any of the 90 tests we count rose 22%.
The tests mentioned with microdialysis
Each bar is one test, with how many of the 133 papers from 2021 to 2025 mention it, and what share that is. A paper that mentions two tests counts under both.
The 15 tests these papers mention most
All 42 tests these papers mention
| Test | Papers | Share of the 133 papers |
|---|---|---|
| Self-administration | 23 | 17% |
| Conditioned place preference | 21 | 16% |
| Forced swim test | 14 | 11% |
| Elevated plus maze | 13 | 10% |
| Open field | 11 | 8% |
| Novel object recognition | 11 | 8% |
| Morris water maze | 10 | 8% |
| Operant conditioning | 9 | 7% |
| Tail suspension test | 8 | 6% |
| Light-dark box | 8 | 6% |
| Wheel running | 7 | 5% |
| Fear conditioning | 7 | 5% |
| Von Frey test | 5 | 4% |
| Sucrose preference test | 5 | 4% |
| Prepulse inhibition and acoustic startle | 5 | 4% |
| Passive avoidance | 4 | 3% |
| Object location test | 4 | 3% |
| Y-maze | 4 | 3% |
| Rotarod | 4 | 3% |
| Treadmill running | 4 | 3% |
| Tail flick | 3 | 2% |
| Formalin test | 3 | 2% |
| Drug discrimination | 2 | 2% |
| Hot plate | 2 | 2% |
| Social interaction test | 2 | 2% |
| Acetone test | 1 | 1% |
| Paw pressure test | 1 | 1% |
| Social approach and avoidance | 1 | 1% |
| Novelty-suppressed feeding | 1 | 1% |
| Catalepsy bar test | 1 | 1% |
| Hole-board | 1 | 1% |
| Nest building | 1 | 1% |
| Grip strength | 1 | 1% |
| Learned helplessness | 1 | 1% |
| Radial arm maze | 1 | 1% |
| Barnes maze | 1 | 1% |
| Five-choice serial reaction time task | 1 | 1% |
| Predator odor exposure | 1 | 1% |
| Three-choice serial reaction time task | 1 | 1% |
| Splash test | 1 | 1% |
| Attentional set shifting | 1 | 1% |
| Rotational behavior (rotometer) | 1 | 1% |
To count the papers that mention two or more tests together, use the test battery tool.
Papers by year
Animal research papers that mention microdialysis and a behavioral test, by year, 2001 to 2026
The 2026 bar counts papers added to PubMed by November 8, 2026.
- Papers in a full year
- 2026 so far
Show the counts for each year
| Year | Papers |
|---|---|
| 2001 | 50 |
| 2002 | 66 |
| 2003 | 58 |
| 2004 | 63 |
| 2005 | 57 |
| 2006 | 51 |
| 2007 | 63 |
| 2008 | 83 |
| 2009 | 61 |
| 2010 | 67 |
| 2011 | 57 |
| 2012 | 50 |
| 2013 | 53 |
| 2014 | 55 |
| 2015 | 64 |
| 2016 | 49 |
| 2017 | 43 |
| 2018 | 35 |
| 2019 | 37 |
| 2020 | 39 |
| 2021 | 40 |
| 2022 | 27 |
| 2023 | 20 |
| 2024 | 27 |
| 2025 | 19 |
| 2026 (part year) | 18 |
Disease models in papers that mention microdialysis
Each bar is one disease model, with how many of the 133 papers from 2021 to 2025 are tagged with it, and what share that is. The model comes from the paper's MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. A paper without MeSH terms gets its model from PubTator 3, NCBI's text-mining service, if PubTator 3 finds the disease in the title or abstract. A paper can count under more than one model.
Papers from 2021 to 2025 by disease model
Which species the papers used
Each bar is a share of the 133 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.
Species
NIH funding
27 of the 133 papers (20%) had NIH funding. NIDA funded the most, 13 of them. A paper counts as NIH-funded when its PubMed record lists an NIH grant, or when NIH RePORTER links it to an NIH project.
NIH-funded papers by institute
Each share is of the NIH-funded papers. A paper with grants from two institutes counts under both.
The most cited papers from 2021 to 2025
These papers from 2021 to 2025 mention microdialysis and a behavioral test and have the most citations, as counted by NIH's iCite on November 5, 2026. We show three of the five most cited papers and leave out two because of words in their titles.
Proc Natl Acad Sci U S A, 2022. 47 citations.
Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice.
Neurobiol Dis, 2023. 43 citations.
Neurochem Int, 2021. 40 citations.
How we counted
A paper counts here when it is animal research and its title or abstract mentions microdialysis and at least one of the 90 behavioral tests. A count is a number of papers, not of experiments, labs or animals. A paper that mentions microdialysis only in its methods is missed, so the count runs low.
A paper is animal research when its MeSH terms name an animal species. If they name none, NCBI's text-mining service PubTator 3 has to find one in the title or abstract. Papers on animals other than mice, rats, zebrafish, flies and primates count only when they also mention a test. Many of them study people or use the same words for something else.
The search terms for microdialysis are in the download Animal models and brain techniques. The counts in the chart of tests are in Tests mentioned with each model or technique. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.
More brain techniques
Each brain technique with 100 or more papers from 2021 to 2025 that mention a test has a page. These are the others, each with that count.
- Intracerebroventricular (ICV) injection 706 papers
- AAV vectors 546 papers
- Chemogenetics (DREADDs) 505 papers
- Optogenetics 443 papers
- In vivo electrophysiology 335 papers
- Intranasal delivery 299 papers
- EEG and ECoG 265 papers
- Intrathecal injection 257 papers
- Fiber photometry 177 papers
- Transcranial stimulation 152 papers
How to cite
APA
ConductScience. (2026, November 13). Behavioral tests with microdialysis [Data set]. https://conductscience.com/resources/data/brain-techniques/microdialysis
BibTeX
@misc{conductscience_microdialysis_2026,
author = {{ConductScience}},
title = {Behavioral tests with microdialysis},
year = {2026},
month = nov,
url = {https://conductscience.com/resources/data/brain-techniques/microdialysis},
note = {Data set, released November 13, 2026},
}Equipment in our store
For studies with microdialysis, our store sells:
Apparatus for the tests
Our store sells apparatus for all the 10 tests these papers mention most.
