Primary Assay — African Turquoise Killifish
Locomotor Activity Decline With Aging
Nothobranchius furzeri
Killifish show progressive locomotor decline mirroring mammalian aging. Total distance, mean velocity, and immobility tracked across the lifespan provide a compressed vertebrate aging model for intervention screening.
Quantitative Output
Measured Parameters
Every parameter is automatically tracked frame-by-frame in the ConductVision pipeline for Nothobranchius furzeri.
| Parameter | Unit | Description |
|---|---|---|
| Total distance per age | mm/10min | Age-dependent decline |
| Mean velocity per age | mm/s | Speed reduction |
| Immobility increase | %/week | Progressive inactivity |
| Activity half-life | weeks | Age at 50% activity loss |
References
Citations for Locomotor Activity Decline With Aging
- Cellerino A, Valenzano DR, Reichard M. (2016). From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology. Biol Rev, 91(2), 511-533. PMID: 25923786
Compatible Equipment
Hardware for African Turquoise Killifish Research
Multi-Well Observation Chamber
Longitudinal locomotion tracking
T-Maze for Small Fish
Learning and memory assays
Social Interaction Tank
Shoaling and aggression by age
Infrared Camera System
Sleep/wake monitoring
Aging Colony Management System
Longitudinal cohort tracking
Related Assays
Other African Turquoise Killifish Primary Assays
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Learning / Memory Aging
Nothobranchius furzeri
Cognitive decline in killifish parallels mammalian aging, with T-maze accuracy and color association learning deteriorat…
03
Social Interaction Changes
Nothobranchius furzeri
Age-related social disengagement in killifish mirrors patterns seen in aging mammals. Shoaling cohesion, aggression, and…
03
Sleep / Activity Patterns
Nothobranchius furzeri
Sleep architecture changes during killifish aging include increased total sleep, activity bout fragmentation, and reduce…
Run Locomotor Activity Decline With Aging on ConductVision
Our team will configure the protocol, camera rig, and analysis pipeline for your african turquoise killifish facility.
