Seizure Stage
Baraban scale classification (Stage I–III) based on locomotor pattern
Automated detection and staging of seizure-like behavior in zebrafish.
Metrics automatically extracted by ConductVision.
Baraban scale classification (Stage I–III) based on locomotor pattern
Number of seizure events per recording period
Length of each seizure episode from onset to termination
Rhythmic convulsive movements detected via high-frequency tracking
Stage III circular swimming pattern characteristic of severe seizures
Reduced activity period following seizure termination
Zebrafish are widely used as a model for epilepsy research due to conserved seizure mechanisms and amenability to high-throughput chemical screening. The Baraban seizure staging system classifies larval zebrafish seizures into Stage I (increased swimming), Stage II (whirlpool swimming), and Stage III (clonus-like convulsions with loss of posture).
ConductVision automatically classifies seizure stages using velocity, trajectory curvature, and posture analysis. The software detects PTZ-induced seizures in 96-well plates, enabling rapid antiepileptic drug screening and genetic modifier identification with quantitative, reproducible seizure metrics.
Related paradigms
Visual discrimination and spatial learning assessment for zebrafish.
Assess sensory processing and anxiety behavior in zebrafish.
Quantify anxiety via scototaxis — innate dark preference — in zebrafish.
Spatial exploration and working memory assessment for zebrafish.
Five-choice serial reaction time task for attention and impulsivity.
Markerless video tracking for social behavior quantification.
Request a demo or contact our team to discuss how ConductVision can accelerate your research.