C-Bend Latency
Time from stimulus onset to initial C-start escape bend
ConductVision · Behavioral Analysis
Zebrafish Acoustic Startle
Measure C-bend escape responses and sensorimotor gating in zebrafish and larvae.
ZebrafishStartle / HabituationAuto Export
ConductVision / Zebrafish Acoustic Startle
Recording / Trial 3fish tracked
C-Bend Latency18.4s
C-Bend Magnitudeauto
Habituation Rateauto
Key Parameters
Metrics automatically extracted by ConductVision.
C-Bend Magnitude
Maximum body curvature angle during the escape response
Habituation Rate
Decline in startle magnitude across repeated stimuli
Prepulse Inhibition
Reduction in startle when preceded by a weak prepulse
Short-Latency C-start
Fast Mauthner-mediated escapes within 15 ms
Escape Distance
Total displacement during the escape swim bout
What is the Zebrafish Acoustic Startle Test?
The acoustic startle response in zebrafish is a rapid, Mauthner neuron-mediated C-bend escape triggered by sudden vibrational or acoustic stimuli. This innate reflex is conserved across vertebrates and provides a robust readout for sensorimotor gating, habituation, and prepulse inhibition — key translational endpoints for schizophrenia and autism research.
ConductVision captures high-speed video (up to 1,000 fps) to resolve sub-millisecond C-start kinetics. The software automatically classifies short-latency and long-latency responses, scores habituation curves, and calculates prepulse inhibition ratios across multi-well plates for high-throughput genetic and drug screens.
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