Research data ยท Home-cage behavior

Nest building

From 2021 to 2025, 422 animal research papers mentioned nest building in their title or abstract, ranking it 31st of the 90 tests we track.

That is 2.0 times the 207 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

422 animal research papers from 2021 to 2025 mentioned the test
2.0 times as many papers as in 2011 to 2015
31st of the 90 tests by papers from 2021 to 2025
48% of these papers used mice

Papers by year

Animal research papers that mention nest building, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200125
200224
200312
200414
200524
200620
200727
200832
200936
201035
201129
201240
201346
201448
201544
201662
201760
201877
201967
202074
202186
202281
202379
202486
202590
2026 (part year)85

Papers that mention nest building in mice and in rats, by year, 2001 to 2025

  • Mouse
  • Rat
Show the counts for each year and species
Papers by year, mice and rats
YearMouseRat
200143
200282
200322
200462
2005103
200642
200762
200864
200995
201073
201192
2012145
2013181
2014193
2015233
2016261
2017252
2018387
2019283
2020344
2021415
2022396
2023354
2024445
2025426

Which species the papers used

Each bar is a share of the 422 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
201 papers 48%
Other animals
192 papers 45%
Rat
26 papers 6%
Nonhuman primate
6 papers 1%
Fruit fly
2 papers under 1%
Zebrafish
1 paper under 1%

โ€œOther animalsโ€ counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 370 of the 422 papers, so each bar is a share of those 370.

C57BL mice
58 papers 16%
Transgenic mice
33 papers 9%
Knockout mice
16 papers 4%
Sprague-Dawley rats
8 papers 2%
Wistar rats
4 papers 1%
BALB/c mice
3 papers 1%
C3H mice
2 papers 1%
129 mice
1 paper under 1%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention nest building and study that disease model, with its share of the 422 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

41 papers 10%
26 papers 6%
14 papers 3%
13 papers 3%
8 papers 2%
6 papers 1%

Tests mentioned alongside nest building

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 422 papers that mention nest building.

Papers from 2021 to 2025 that mention both tests

29 papers 7%
25 papers 6%
22 papers 5%
18 papers 4%
17 papers 4%
14 papers 3%
12 papers 3%

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention nest building and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Mapping the effects of pregnancy on resting state brain activity, white matter microstructure, neural metabolite concentrations and grey matter architecture.

    Nat Commun, 2022. 79 citations.

  2. Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman syndrome mouse model.

    JCI Insight, 2021. 72 citations.

  3. Welfare of pigs on farm.

    EFSA J, 2022. 70 citations.

  4. Bifidobacterium Lactis Probio-M8 regulates gut microbiota to alleviate Alzheimer's disease in the APP/PS1 mouse model.

    Eur J Nutr, 2021. 61 citations.

  5. HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury.

    J Neuroinflammation, 2021. 52 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions nest building only in its methods is missed, so the count runs low. The count includes 28 reviews. For 52 of the 422 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More home-cage behavior tests

These home-cage behavior tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Nest building in published research [Data set]. https://conductscience.com/data/behavioral-tests/nest-building

BibTeX

@misc{conductscience_nest_building_2026,
  author = {{ConductScience}},
  title = {Nest building in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/nest-building},
  note = {Data set, released November 10, 2026},
}