Research data ยท Home-cage behavior

Self-grooming

From 2021 to 2025, 447 animal research papers mentioned self-grooming in their title or abstract, ranking it 29th of the 90 tests we track.

That is 1.6 times the 278 papers of 2011 to 2015. Papers that mention any of the 90 tests grew to 1.2 times as many over the same span.

447 animal research papers from 2021 to 2025 mentioned the test
1.6 times as many papers as in 2011 to 2015
29th of the 90 tests by papers from 2021 to 2025
47% of these papers used mice and 27% used rats

Papers by year

Animal research papers that mention self-grooming, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200128
200230
200331
200431
200535
200639
200717
200843
200933
201033
201144
201257
201354
201455
201568
201656
201768
201871
201973
202070
202199
202297
202392
202467
202592
2026 (part year)100

Papers that mention self-grooming fell from 99 in 2021 to 67 in 2024, then rose to 92 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's species from PubMed's indexing whenever it names one, so part of this dip may come from the indexing rather than from fewer studies.

Papers that mention self-grooming in mice and in rats, by year, 2001 to 2025

  • Mouse
  • Rat
Show the counts for each year and species
Papers by year, mice and rats
YearMouseRat
2001121
2002418
2003716
2004816
2005619
2006717
200776
2008724
20091113
20101512
20111918
20122117
20131618
20141621
20152023
20161518
20172325
20182526
20193022
20202726
20215621
20223927
20233829
20243119
20254726

Which species the papers used

Each bar is a share of the 447 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
211 papers 47%
Rat
122 papers 27%
Other animals
99 papers 22%
Fruit fly
12 papers 3%
Nonhuman primate
11 papers 2%

โ€œOther animalsโ€ counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 375 of the 447 papers, so each bar is a share of those 375.

C57BL mice
85 papers 23%
Knockout mice
38 papers 10%
Wistar rats
29 papers 8%
Sprague-Dawley rats
26 papers 7%
Other inbred mice
14 papers 4%
Transgenic mice
10 papers 3%
Long-Evans rats
4 papers 1%
ICR mice
3 papers 1%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention self-grooming and study that disease model, with its share of the 447 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

Tests mentioned alongside self-grooming

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 447 papers that mention self-grooming.

Papers from 2021 to 2025 that mention both tests

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention self-grooming and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties.

    Brain Behav Immun, 2022. 140 citations.

  2. Neural control of affiliative touch in prosocial interaction.

    Nature, 2021. 114 citations.

  3. A Drosophila computational brain model reveals sensorimotor processing.

    Nature, 2024. 57 citations.

  4. Novel ADNP Syndrome Mice Reveal Dramatic Sex-Specific Peripheral Gene Expression With Brain Synaptic and Tau Pathologies.

    Biol Psychiatry, 2022. 57 citations.

  5. Xiaoyaosan ethyl acetate fraction alleviates depression-like behaviors in CUMS mice by promoting hippocampal neurogenesis via modulating the IGF-1Rฮฒ/PI3K/Akt signaling pathway.

    J Ethnopharmacol, 2022. 51 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions self-grooming only in its methods is missed, so the count runs low. The count includes 7 reviews. For 72 of the 447 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More home-cage behavior tests

These home-cage behavior tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Self-grooming in published research [Data set]. https://conductscience.com/data/behavioral-tests/self-grooming

BibTeX

@misc{conductscience_self_grooming_2026,
  author = {{ConductScience}},
  title = {Self-grooming in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/self-grooming},
  note = {Data set, released November 10, 2026},
}