ConductScience Pathology & Histology

Process. Section. Stain. Quantify.

Tissue processing, microtomy, slide preparation, and computer vision image analysis for research labs.

Build a workflow planExplore ConductVision Image
ConductVision Image v2.4.1 / signed / current
Histology lab bench with tissue preparation instruments and computer vision slide analysis

Microtome

Slide QC

ConductVision

7 steps

Complete tissue-to-data lane

8 hardware lines

Microtomy, processing, embedding, staining

1 software stack

ConductVision Image, Microscopy, Morphology

Research use

Reproducible. Auditable. No diagnostic claims.

Section 01 / Workflow Builder

Build the bench around the tissue, stain, and output.

Select the starting conditions. The planner returns the hardware lane, ConductVision lane, free tools, Lab Manager starter files, and a quote URL that carries the choices forward.

Tissue type
Stain or output
Throughput
Current state

Section 02 / Workflow Overview

One workflow. Two lanes.

Hardware shapes the slide. ConductVision turns the slide into measurements. Start where you need to start. We fit the rest around it.

Lane A

Histology bench

4 stages
01

Process

Fix, dehydrate, infiltrate.

Instrument role

Tissue processors standardize fixation, dehydration, clearing, and paraffin infiltration before the sample reaches the cutting bench.

ConductVision role

This is the pre-analytics gate. The downstream image workflow records processing method, tissue type, and batch context against the slide set.

Output

Processed cassette batch with method context ready for embedding.

See tissue processors
02

Embed

Orient and block in paraffin.

Instrument role

Embedding stations, heated forceps, cold plates, and molds set orientation before sectioning quality is determined.

ConductVision role

Orientation notes and cassette IDs travel forward so review overlays can be tied back to preparation choices.

Output

Oriented paraffin blocks with traceable cassette IDs.

See embedding systems
03

Section

Microtomy and cryosectioning.

Instrument role

Manual, semi-automatic, rotary microtomes, and floor-standing cryostats create repeatable section thickness and ribbon quality.

ConductVision role

Section quality becomes the first visible QC signal before automated quantification starts.

Output

Mounted paraffin or frozen sections ready for staining.

See microtomes
04

Stain

H&E, IHC, special stains.

Instrument role

Stainers, water baths, slide warmers, and coverslippers finish the slide and reduce manual variability.

ConductVision role

Stain type selects the matching analysis preset, including H&E nuclei, DAB percent area, fibrosis, or morphology review.

Output

Finished slides with stain-specific analysis intent.

See stainers
slide handoff

Lane B

ConductVision analysis

3 stages
05

Image

Slide and field-level capture.

Instrument role

Microscopes and slide cameras provide the field, magnification, and illumination conditions for analysis.

ConductVision role

ConductVision Microscopy and Image organize capture, calibration, batch naming, and region selection.

Output

Captured slide fields with acquisition metadata.

See microscopy CV
06

Quantify

Nuclei, DAB, fibrosis, area.

Instrument role

The hardware lane supplies consistent sections and stain quality so measurements are comparable across batches.

ConductVision role

ConductVision Image applies nuclei, DAB, percent-area, morphology, and batch-processing routines with visible overlays.

Output

Per-region measurements, overlays, QC flags, and review states.

See image analysis
07

Export

CSV, overlays, methods, audit.

Instrument role

Bench instruments remain part of the exported method trail rather than being separated from the analysis result.

ConductVision role

Exports package CSV tables, overlay images, methods text, and audit-friendly batch summaries for research reporting.

Output

Research-ready data package with method context.

Request workflow
Hardware-ledConductVision-poweredOpen a stage to configure the handoff

Section 03 / Two Buying Lanes

I need slides. I need answers.

Most labs need both. Configure each lane independently or as a bundle.

Lane A / Hardware-led

Histology Instruments

Reliable tissue-prep bench. Processing, microtomy, embedding, staining, slide finishing.

MicrotomesTissue processorsCryostatsEmbeddingStainersWater baths
Histology bench lineup with microtome, tissue processing, staining, water bath, slide racks, and reagent bottles

Open hub

Lane B / Software-led

Pathology Image Analysis

Quantify H&E nuclei, IHC and DAB, tissue area, morphology, and section quality.

H&E nucleiIHC and DABTissue areaSection QCMorphologyBatch reporting
ConductVision pathology image analysis software interface with H&E slide overlays and results table

Open hub

Section 04 / Free Planning Tools

Calculators before quote requests.

Each tool should return a concrete planning output: a product path, a ConductVision package, a CSV where useful, and quote context that does not need to be retyped.

Open tools hub

Microtome vs Cryostat Selector

Pick the right sectioning instrument for your tissue, section temperature, and downstream stain.

Inputs: Tissue, thickness, temperature, throughput

Output: Instrument class, why it fits, product links

Run tool

Tissue Processor Capacity Planner

Turn cassette volume, run frequency, and protocol length into a processor capacity recommendation.

Inputs: Cassettes per day, run schedule, protocol length

Output: Batch capacity, bottleneck warning, processor class

Run tool

Histology Bench Budget Planner

Separate required bench items from optional automation and prepare a quote-ready configuration.

Inputs: New lab or upgrade, workflow steps, automation level

Output: Budget categories, required vs optional, CSV

Run tool

H&E Staining Run Planner

Plan slides per run, racks, reagent refresh, coverslipping, and QC checks.

Inputs: Slides per run, racks, reagent schedule

Output: Run checklist, QC checks, stainer recommendation

Run tool

Pathology Image Analysis Planner

Map stain, image source, endpoint, ROI workflow, and batch size to a ConductVision package.

Inputs: Stain, image source, endpoint, ROI, batch

Output: CV package, overlays, CSV, methods text

Run tool

Section 05 / Free Lab Manager Resource

Track this bench after the purchase decision.

Lab Manager is the free operating layer for inventory, equipment records, calibration windows, maintenance logs, budgets, and SOP documents. The page should give customers a starter pack they can import.

View Lab Manager on GitHub

histology-equipment-starter.csv

Equipment records for microtomes, cryostats, processors, stainers, warmers, and coverslippers.

14 rows

histology-reagents-consumables.csv

Starter inventory rows for blades, slides, cassettes, paraffin, stains, alcohols, and mounting media.

12 rows

histology-maintenance-schedule.csv

Inspection, cleaning, calibration, and service cadence for the preparation bench.

10 rows

histology-budget-categories.csv

Budget categories that separate required instruments, automation, consumables, and software.

8 rows

histology-sop-document-checklist.csv

SOP, manual, certificate, and methods-document checklist for shared lab operation.

11 rows

Section 06 / Purchasing Guides

Buying guidance at the decision point.

The page should not force customers to infer what matters. These guide cards explain the next buying decision and connect it to tools, products, and ConductVision outputs.

Setup

Buying your first histology bench

What to buy first, what can wait, and which items are required for reliable slide preparation.

Selection

Microtome vs cryostat

Choose paraffin sectioning, frozen sectioning, or a hybrid path based on tissue and endpoint.

Throughput

Tissue processor capacity and automation

Use cassette volume, protocol duration, and staffing constraints to decide when automation helps.

Quality

How slide preparation affects image analysis

Connect folds, chatter, tissue coverage, and stain uniformity to ConductVision QC and exports.

Section 07 / Buyer Matrix

Choose your workflow.

Start from the sample and stain. The buying path should show the hardware lane, ConductVision package, and output the lab can expect.

Use case

Routine H&E quantification

Sample and stain

Paraffin sections, H&E stain

Throughput

Single lab or small batch runs

Recommended setup

Microtome, water bath, slide warmer + ConductVision Image with H&E nuclei and histology QC presets

Expected output

Nuclei density, tissue coverage, QC flags, overlay PNGs, CSV

Use case

IHC and DAB analysis

Sample and stain

Paraffin sections, chromogenic IHC

Throughput

Study batches and repeat panels

Recommended setup

Tissue processor, embedding station, rotary microtome, stainer + DAB percent-positive area, intensity bins, ROI review

Expected output

Positive area, optical density, region summaries, methods text

Use case

Frozen section and neurohistology

Sample and stain

Fresh frozen tissue, brain sections, morphology stains

Throughput

Protocol-driven research cohorts

Recommended setup

Cryostat, slide warmer, microscope capture path + ConductVision Morphology plus Image QC and batch exports

Expected output

Morphometry tables, field overlays, section artifact review

Use case

High-throughput core lab

Sample and stain

Mixed tissues, H&E, IHC, special stains

Throughput

Multi-user queue and shared methods

Recommended setup

Processor, embedding, microtome, stainer, coverslipper + Locked protocols, batch reporting, review states, audit trail

Expected output

Per-slide metrics, batch consistency view, CSV and protocol JSON

Section 08 / Featured Hardware

Eight categories. One bench.

Each line is configurable as a standalone instrument or as part of a workflow bundle.

See all instruments
Rotary microtome with paraffin block, blade holder, and prepared histology slidesmicrotomes

Microtomes

7 products. Manual, semi-auto, rotary.

Automated carousel tissue processor with reagent stations and cassette baskettissue processors

Tissue processors

11 products. Processing, embedding, cassette support.

Digital tissue embedding workstation with paraffin dispenser, molds, and cold plateembedding systems

Embedding systems

Embedding station. Heated paraffin and cold plate.

Floor-standing cryostat freezing microtome beside a histology bench with slide racks and specimen moldscryostats

Cryostats

1 product. Floor-standing frozen section microtome.

Digital tissue flotation water bath with paraffin ribbons and slide dryer surfacewater baths

Water baths

Flotation bath. Ribbon handling and slide transfer.

Digital slide warmer hot plate with rows of prepared microscope slidesslide warmers

Slide warmers

Slide dryer. Flat-bed warming and drying.

Automated slide stainer with reagent tanks, slide racks, and touchscreen controlstainers

Stainers

12 products. H&E, special staining, drying, coverslipping.

Automated coverslipping workstation with slide input racks and mounting medium bottlecoverslipping

Coverslipping

Automated coverslipper. Glass, film, mounting media.

Section 09 / ConductVision Layer

The software half of the lane.

ConductVision adds QC, quantification, and reporting on top of microscope fields or slide-scanner image exports. Use it as a histology gate, a pathology analysis engine, or both.

Feature 01

Histology QC

Fold detection, chatter, tissue coverage, stain uniformity, and slide-level review state.

Feature 02

H&E nuclei

Per-region nuclei count, density, tissue coverage, and visible overlays for routine H&E fields.

Feature 03

IHC and DAB

Percent-positive area, optical density, intensity bins, and ROI-level DAB summaries.

Feature 04

Section artifacts

Flag tears, folds, missing tissue, and inconsistent staining across batches.

Feature 05

Batch reporting

Per-slide metrics rolled into batch consistency views for shared methods and core facilities.

Feature 06

Exports

CSV tables, overlay PNGs, methods text, locked protocol JSON, and audit-friendly summaries.

See ConductVision Image features

Example analysis package

Overlay review

Annotated PNGs show nuclei, DAB-positive regions, tissue masks, artifacts, and reviewed ROIs.

Measurement tables

CSV exports include per-region counts, density, percent area, optical density, and slide identifiers.

Methods package

Methods text, locked protocol JSON, batch summary, and review state travel with the result set.

Section 10 / Workflow Bundles

Pre-configured starting points.

Three bundles cover the most common research benches. Each is quote-ready and configurable.

Bundle 01

Histology Quantification Starter

Sectioning bench plus ConductVision Image with H&E presets.

Best for

  • Labs moving from manual slide review to repeatable H&E measurement.

Includes

  • Manual microtome
  • Water bath
  • Slide warmer
  • ConductVision Image H&E preset

Outputs

  • Nuclei count and density
  • Tissue coverage QC
  • Overlay images and CSV tables

Optional add-ons

  • Microscopy capture setup
  • Additional H&E protocol templates
Quote-readyConfigure

Bundle 02

Preclinical Pathology Quantification

A full sample-to-data lane for rodent studies, IHC and DAB.

Best for

  • Preclinical teams running repeat animal cohorts with IHC endpoints.

Includes

  • Tissue processor
  • Embedding workstation
  • Rotary microtome
  • ConductVision Image IHC/DAB workflow

Outputs

  • DAB percent-positive area
  • Intensity bins
  • ROI summaries and methods text

Optional add-ons

  • Slide stainer
  • Automated coverslipper
  • Batch reporting setup
Quote-readyConfigure

Bundle 03

Neurohistology Morphometry

Cryosection bench plus ConductVision Morphology and Image.

Best for

  • Neuroscience labs sectioning frozen tissue and measuring morphology.

Includes

  • Floor-standing cryostat
  • Slide warmer
  • ConductVision Morphology
  • ConductVision Image QC

Outputs

  • Morphometry measurements
  • Section artifact flags
  • Field overlays and CSV exports

Optional add-ons

  • Microscopy workflow calibration
  • Study-specific morphology templates
Quote-readyConfigure

Section 11 / Recommended Next Step

Build a pathology and histology workflow quote.

Tell us what you are sectioning and what you need to measure. We come back with a hardware and ConductVision configuration that fits your bench, sample type, and throughput.

Start a quotePlan the benchPlan analysis