Medical Device & Pharma QC

Microsphere Analysis

Count, diameter & size distribution for drug-delivery and calibration microspheres

Microsphere Analysis — ConductVision Image analysis
D10/D50/D90
Number-weighted
Span / CV%
Polydispersity
Lognormal
Distribution fit

Example outputs shown for illustration. Numbers depend on your samples and protocol.

Image: SEM of spherical microparticles — Altynay.Kaiyrgali, CC BY 4.0, via Wikimedia Commons

Results

What the analysis returns, tied back to the image it came from.

Diameter distribution with lognormal fit

Count-per-bin histogram with normal and lognormal fits and D10/D50/D90 — reported number-weighted (by count), not volume-weighted.

Micrometer-calibrated scale

Calibrate against a known length or scale bar so diameters are reported in real microns; accuracy depends on your calibration standard.

Touching-sphere separation

Separates contacting microspheres and excludes border particles for accurate counts, in line with ISO 13322-1 image-analysis practice.

Built for medical-device & pharma QC

Span and CV% for monodispersity, spec pass/fail, and audit-friendly exports. For compendial (USP/EP) compliance, confirm method comparability with your regulatory team.

From image to reviewed result

  1. 1

    Upload

    Load microscopy or SEM images of microspheres

  2. 2

    Calibrate

    Set the pixels-per-micron scale

  3. 3

    Measure

    AI detects spheres and measures equivalent diameter

  4. 4

    Export

    Download diameter distribution, D-values, and per-particle data

Microsphere size analyzer: detected spheres and their number-weighted diameter distribution with D10/D50/D90 and a lognormal fit.Microsphere Size AnalyzerUpload a micrograph → auto-detect spheres → diameter distribution · D-values · QC pass/failRuns in your browserDETECTED PARTICLESDashed = border / non-spherical, excluded per ISO 13322-156 µm52 µm60 µm20 µmDIAMETER DISTRIBUTIONnumber-weighted (by count)Diameter (µm)Count0153045607590D10 28D50 42D90 61Lognormal fits bestR² 0.98 vs normal 0.91Particles (n)2,140Median D5042 µmSpan0.78CV% / GSD19% 1.22QC spec PASSD90 ≤ 65 µm ✓ CV ≤ 25% ✓ span ≤ 1.0 ✓
Microsphere diameter distribution with D10/D50/D90 and lognormal fit
Demo output

From micrograph to diameter distribution

Detected spheres, a number-weighted diameter histogram with a lognormal fit, D10/D50/D90 markers, and a QC pass/fail verdict.

Count & diameter

Equivalent-circle diameter per sphere with total count

D10/D50/D90 & span

Number-weighted percentiles and breadth

Distribution fit

Normal and lognormal fits with goodness-of-fit

Works with your existing tools

Excel
GraphPad Prism
RR
Python
CSV

Microsphere Analysis with ConductVision Image

Measure microsphere count, diameter, and size distribution from microscopy images for medical-device and pharmaceutical QC — drug-delivery microspheres, embolization beads, and calibration beads. ConductVision separates touching spheres, reports number-weighted D10/D50/D90 and span, and builds a diameter histogram with lognormal fit.

Talk to a scientist

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Send a representative image and your measurement goal. A ConductVision scientist will confirm whether this is the right fit, or point you to the closer workflow, before you commit to a quote.

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We will show the closest ConductVision workflow and flag what needs custom validation for your images.