Medical Device & Pharma QC

Microsphere Analysis

Count, diameter & size distribution for drug-delivery and calibration microspheres

Measure microsphere count, diameter, and size distribution from microscopy images for medical-device and pharmaceutical QC — drug-delivery microspheres, embolization beads, and calibration beads. ConductVision separates touching spheres, reports number-weighted D10/D50/D90 and span, and builds a diameter histogram with lognormal fit.

Try This Protocol View All Applications

D10/D50/D90

Number-weighted

Span / CV%

Polydispersity

Lognormal

Distribution fit

Demo output

From micrograph to diameter distribution

Detected spheres, a number-weighted diameter histogram with a lognormal fit, D10/D50/D90 markers, and a QC pass/fail verdict.

Count & diameter

Equivalent-circle diameter per sphere with total count

D10/D50/D90 & span

Number-weighted percentiles and breadth

Distribution fit

Normal and lognormal fits with goodness-of-fit

Workflow

How It Works

Upload

Load microscopy or SEM images of microspheres

Calibrate

Set the pixels-per-micron scale

Measure

AI detects spheres and measures equivalent diameter

Export

Download diameter distribution, D-values, and per-particle data

Features

What You Get

Diameter distribution with lognormal fit

Count-per-bin histogram with normal and lognormal fits and D10/D50/D90 — reported number-weighted (by count), not volume-weighted.

Micrometer-calibrated scale

Calibrate against a known length or scale bar so diameters are reported in real microns; accuracy depends on your calibration standard.

Touching-sphere separation

Separates contacting microspheres and excludes border particles for accurate counts, in line with ISO 13322-1 image-analysis practice.

Built for medical-device & pharma QC

Span and CV% for monodispersity, spec pass/fail, and audit-friendly exports. For compendial (USP/EP) compliance, confirm method comparability with your regulatory team.

Compatibility