Research data · Disease model and test
Wheel running in Alzheimer disease research
From 2021 to 2025, 36 animal research papers on Alzheimer disease mentioned wheel running in their title or abstract.
That is 2.4 times the 15 papers of 2011 to 2015. Between the same two periods, the papers on Alzheimer disease that mention any of the 90 tests we count grew faster, to 2.8 times as many.
Papers by year
Animal research papers on Alzheimer disease that mention wheel running, by year, 2001 to 2026
The 2026 bar counts papers added to PubMed by November 8, 2026.
- Papers in a full year
- 2026 so far
Show the counts for each year
| Year | Papers |
|---|---|
| 2001 | 0 |
| 2002 | 1 |
| 2003 | 0 |
| 2004 | 0 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 5 |
| 2009 | 2 |
| 2010 | 0 |
| 2011 | 3 |
| 2012 | 5 |
| 2013 | 1 |
| 2014 | 2 |
| 2015 | 4 |
| 2016 | 7 |
| 2017 | 3 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 11 |
| 2021 | 5 |
| 2022 | 13 |
| 2023 | 3 |
| 2024 | 8 |
| 2025 | 7 |
| 2026 (part year) | 9 |
Papers on Alzheimer disease that mention wheel running fell from 5 in 2021 to 3 in 2023, then rose to 7 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.
Which species the papers used
Each bar is a share of the 36 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.
Species
“Other animals” counts papers that use none of the species this chart names.
Tests mentioned alongside wheel running
Each bar is one test, with how many of the 36 papers also mention it, and what share that is. Of these papers, 25 (69%) mention no other test.
The 12 tests these papers mention most
Which papers count
A paper counts here when it is animal research, mentions wheel running in its title or abstract, and studies Alzheimer disease.
We tell whether a paper studies Alzheimer disease from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.
The page on Alzheimer disease research names the subject headings we count as Alzheimer disease. Download the test list for the search terms we used for wheel running, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.
More tests and disease models
Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.
Papers on Alzheimer disease that mention other tests
- Morris water maze 1,456 papers
- Novel object recognition 568 papers
- Y-maze 471 papers
- Passive avoidance 262 papers
- Open field 185 papers
- Elevated plus maze 143 papers
- Fear conditioning 125 papers
- Barnes maze 96 papers
- Treadmill running 73 papers
- Rotarod 56 papers
- T-maze 55 papers
- Object location test 49 papers
- Forced swim test 48 papers
- Radial arm maze 47 papers
- Nest building 41 papers
- Tail suspension test 30 papers
Papers on other disease models that mention wheel running
The page on wheel running counts all the papers that mention it, whatever they study. The page on Alzheimer disease research ranks the tests by their papers on Alzheimer disease.
How to cite
APA
ConductScience. (2026, November 10). Wheel running in Alzheimer disease research [Data set]. https://conductscience.com/data/behavioral-tests/models/alzheimers-disease/running-wheel
BibTeX
@misc{conductscience_alzheimers_disease_running_wheel_2026,
author = {{ConductScience}},
title = {Wheel running in Alzheimer disease research},
year = {2026},
month = nov,
url = {https://conductscience.com/data/behavioral-tests/models/alzheimers-disease/running-wheel},
note = {Data set, released November 10, 2026},
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