Research data · Disease model and test

Fear conditioning in post-traumatic stress research

From 2021 to 2025, 222 animal research papers on post-traumatic stress mentioned fear conditioning in their title or abstract.

That is 2.0 times the 113 papers of 2011 to 2015. Between the same two periods, the papers on post-traumatic stress that mention any of the 90 tests we count grew more slowly, to 1.8 times as many.

222 papers on post-traumatic stress from 2021 to 2025 mentioned fear conditioning
57% of the papers on post-traumatic stress that mention any test mention fear conditioning
11% of the papers that mention fear conditioning are on post-traumatic stress
2.0 times as many papers as in 2011 to 2015

Papers by year

Animal research papers on post-traumatic stress that mention fear conditioning, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
20010
20021
20031
20042
20055
20068
20078
20089
20095
20108
201110
201225
201314
201438
201526
201635
201730
201852
201953
202052
202166
202231
202330
202442
202553
2026 (part year)39

Papers on post-traumatic stress that mention fear conditioning fell from 66 in 2021 to 30 in 2023, then rose to 53 in 2025. Part of this dip may come from PubMed's indexing rather than from fewer studies. Where PubMed has indexed a paper, we take its disease models from that indexing. Otherwise PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract, or the paper is not counted here. Papers that PubMed indexed under the subject heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025.

Which species the papers used

Each bar is a share of the 222 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
101 papers 45%
Rat
101 papers 45%
Other animals
24 papers 11%

“Other animals” counts papers that use none of the species this chart names.

Tests mentioned alongside fear conditioning

Each bar is one test, with how many of the 222 papers also mention it, and what share that is. Of these papers, 159 (72%) mention no other test.

The 12 tests these papers mention most

Which papers count

A paper counts here when it is animal research, mentions fear conditioning in its title or abstract, and studies post-traumatic stress.

We tell whether a paper studies post-traumatic stress from its MeSH terms, the subject headings the National Library of Medicine adds when it indexes a paper. For a paper without MeSH terms, PubTator 3, NCBI's text-mining service, has to find the disease in the title or abstract. A paper can count under more than one disease model. A paper that mentions the test only in its methods is missed, so the count runs low.

The page on post-traumatic stress research names the subject headings we count as post-traumatic stress. Download the test list for the search terms we used for fear conditioning, or the paper list for the PubMed ID of every paper behind these counts. Our main page, Behavioral tests in published research, has the full method and each source's terms of use.

More tests and disease models

Every pairing of a disease model and a test with 30 or more papers from 2021 to 2025 has a page like this one.

The page on fear conditioning counts all the papers that mention it, whatever they study. The page on post-traumatic stress research ranks the tests by their papers on post-traumatic stress.

How to cite

APA

ConductScience. (2026, November 10). Fear conditioning in post-traumatic stress research [Data set]. https://conductscience.com/data/behavioral-tests/models/ptsd/fear-conditioning

BibTeX

@misc{conductscience_ptsd_fear_conditioning_2026,
  author = {{ConductScience}},
  title = {Fear conditioning in post-traumatic stress research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/models/ptsd/fear-conditioning},
  note = {Data set, released November 10, 2026},
}

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