Research data ยท Fear and avoidance

Passive avoidance

From 2021 to 2025, 1,142 animal research papers mentioned passive avoidance in their title or abstract, ranking it 15th of the 90 tests we track.

That is 10% fewer than the 1,267 papers of 2011 to 2015. Papers that mention any of the 90 tests rose 22% over the same span. The 2021 to 2025 count may run low because of a dip in PubMed's indexing, explained under the year chart.

1,142 animal research papers from 2021 to 2025 mentioned the test
10% fewer papers than in 2011 to 2015
15th of the 90 tests by papers from 2021 to 2025
56% of these papers used rats and 42% used mice

Papers by year

Animal research papers that mention passive avoidance, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
2001173
2002176
2003175
2004179
2005191
2006207
2007189
2008200
2009198
2010217
2011232
2012261
2013258
2014239
2015277
2016260
2017267
2018256
2019247
2020247
2021281
2022243
2023195
2024195
2025228
2026 (part year)163

Papers that mention passive avoidance fell from 281 in 2021 to 195 in 2023, then rose to 228 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's species from PubMed's indexing whenever it names one, so part of this dip may come from the indexing rather than from fewer studies.

Papers that mention passive avoidance in mice and in rats, by year, 2001 to 2025

  • Mouse
  • Rat
Show the counts for each year and species
Papers by year, mice and rats
YearMouseRat
200152115
200249115
200365106
200461115
200563123
200693106
200780105
200883111
200996101
2010106104
2011110128
2012112145
2013118147
201499143
2015114160
2016126136
2017124143
2018111136
2019104139
2020106139
2021119157
2022110128
202375118
202483107
202591131

Which species the papers used

Each bar is a share of the 1,142 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Rat
641 papers 56%
Mouse
478 papers 42%
Other animals
26 papers 2%
Zebrafish
20 papers 2%
Fruit fly
1 paper under 1%
Nonhuman primate
1 paper under 1%

โ€œOther animalsโ€ counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 906 of the 1,142 papers, so each bar is a share of those 906.

Wistar rats
306 papers 34%
Sprague-Dawley rats
86 papers 9%
C57BL mice
84 papers 9%
Transgenic mice
33 papers 4%
ICR mice
24 papers 3%
Knockout mice
12 papers 1%
BALB/c mice
11 papers 1%
Long-Evans rats
6 papers 1%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention passive avoidance and study that disease model, with its share of the 1,142 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

262 papers 23%
90 papers 8%
43 papers 4%
41 papers 4%
28 papers 2%

Tests mentioned alongside passive avoidance

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 1,142 papers that mention passive avoidance.

Papers from 2021 to 2025 that mention both tests

368 papers 32%
176 papers 15%
150 papers 13%
101 papers 9%
50 papers 4%
46 papers 4%

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention passive avoidance and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson's disease model.

    J Neuroinflammation, 2021. 144 citations.

  2. A review of behavioral methods for the evaluation of cognitive performance in animal models: Current techniques and links to human cognition.

    Physiol Behav, 2022. 110 citations.

  3. Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.

    Geroscience, 2022. 86 citations.

  4. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease.

    Biomed Pharmacother, 2022. 80 citations.

  5. What animal models can tell us about long-term cognitive dysfunction following sepsis: A systematic review.

    Neurosci Biobehav Rev, 2021. 75 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions passive avoidance only in its methods is missed, so the count runs low. The count includes 12 reviews. For 237 of the 1,142 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More fear and avoidance tests

These fear and avoidance tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Passive avoidance in published research [Data set]. https://conductscience.com/data/behavioral-tests/passive-avoidance

BibTeX

@misc{conductscience_passive_avoidance_2026,
  author = {{ConductScience}},
  title = {Passive avoidance in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/passive-avoidance},
  note = {Data set, released November 10, 2026},
}

Apparatus for passive avoidance

Our store sells one product for passive avoidance.

Shop the apparatus

Papers that name our apparatus

We keep our own list of published papers whose text names our equipment. Those that mention passive avoidance in the title or abstract are already in the counts above.

  • 11 papers from 2021 to 2025 name our Active/Passive Avoidance Shuttle Box. See the papers