Lab-on-a-chip guide

Choose the microfluidic chip, pump, and setup for your experiment.

Start with your workflow, then choose the chip format, flow-control setup, accessories, and support needed to run it.

Transparent microfluidic chip with connected tubing

Chip and tubing reference

Transparent device, inlet path, and benchtop setup context.

Microchannel routing map

Workflow to setup path

SampleBufferCellsMixerCollect
Aqueous
Sample
Biology

Choose by application

Start with the experiment.

Pick the closest workflow and jump to a chip family, setup, and quote path.

Droplet generation

Make consistent droplets, emulsions, or encapsulated samples.

Setup
Droplet chip, stable dual-flow control

Cell culture

Perfuse cells, organ-on-chip models, or live microscopy workflows.

Setup
Biocompatible chip, gentle flow

Drug screening

Run dose-response, gradient, or parallel exposure studies.

Setup
Multi-channel chip, repeatable flow

Electrophoresis

Separate analytes in microchannels with controlled detection.

Setup
Glass or specialty chip, buffer compatibility

LNP / nanoparticles

Mix formulation streams at controlled ratios and residence times.

Setup
Micromixer or flow-focusing chip, solvent-compatible path
ports + dimensions

Custom design

Specify geometry, ports, material, optical path, or scale-up needs.

Setup
Drawing or sketch, target material

Setup builder preview

A chip recommendation is incomplete without the setup around it.

Show the chip, pump, tubing, holder, protocol, and quote route together so the setup is easy to plan.

Setup overview

Reuse this same visual pattern in notes and finder results.

PumpTubingChipHolderCollect
Setup PartWhat the User ChoosesRoute
ChipFormat, material, channel layout, ports, and optical path.Open path
Flow controlSyringe pump, pressure pump, peristaltic pump, or existing instrument match.Open path
Fluid pathTubing, fittings, connectors, short fluid path, collection supplies.Open path
FabricationSpin coating, bonding, hot plates, plasma treatment, and PDMS processing.Open path
ProtocolPriming, flow-rate range, imaging, cleaning, and bubble prevention.Open path
Quote pathStock item, configured bundle, or custom technical review.Open path

Material decision

Compare materials like an engineering decision.

Material choice changes optical performance, solvent exposure, cell behavior, and fabrication path. Keep this as a real comparison table.

PDMS

Best fit
Cell culture, fast prototyping, optical microscopy, gas exchange.
Check before ordering
Small molecule absorption, surface treatment, swelling, reuse expectations.
Decision note
Often the first prototyping route for biology-focused chips.

PMMA

Best fit
Rigid polymer chips, teaching labs, disposable assays, lower-cost runs.
Check before ordering
Solvent compatibility, bonding method, temperature exposure.
Decision note
Useful when a rigid disposable format matters more than gas exchange.

Glass

Best fit
High optical clarity, solvent resistance, pressure tolerance, droplet work.
Check before ordering
Cost, fragility, connector and holder requirements.
Decision note
Strong default when imaging and chemistry both matter.

Silicon / quartz

Best fit
Thermal, optical, or chemically demanding specialty workflows.
Check before ordering
Application-specific fabrication and quoting constraints.
Decision note
Usually needs a technical review before ordering.

Paper

Best fit
Low-cost diagnostics, environmental testing, colorimetric field assays.
Check before ordering
Whether the assay truly needs open porous flow vs closed channels.
Decision note
Best for quick detection tests and field-style readouts.

Application notes

Build these as visual protocols.

Each note shows the workflow, products, difficulty, and checks before ordering.

DropletsIntermediate

Droplet generation starter workflow

Droplet chip, syringe or pressure pump, tubing, oil/surfactant review.

Ready for article buildout

Cell cultureIntermediate

PDMS cell culture perfusion workflow

PDMS chip, sterile tubing, bubble prevention, microscope holder.

Needs scientific review

Drug screeningAdvanced

8-channel drug screening gradient workflow

Gradient chip, multi-channel pump, connector plan, imaging setup.

Needs product mapping

MaterialsFoundational

Choosing PDMS vs PMMA vs glass chips

Material comparison, solvent check, optical check, quote trigger.

Ready for article buildout

Custom handoff

Move to technical review when the catalog stops fitting.

The custom path should collect the information a scientist or fabrication partner needs before the team reviews a design or quote.

Structured intake preview

MaterialInlet countWidth / depthDetection pathOutlet / collectQuantity
Workflow
Target material
Sample type
Flow-rate range
Imaging or detection method
Sterility or biocompatibility
Quantity
Drawing or reference chip

Next step

Use the Chip Finder to turn a workflow into a setup sheet.

Open Chip Finder