Research data ยท Activity and exploration

Hole-board

From 2021 to 2025, 206 animal research papers mentioned the hole-board in their title or abstract, ranking it 41st of the 90 tests we track.

That is 13% fewer than the 236 papers of 2011 to 2015. Papers that mention any of the 90 tests rose 22% over the same span. The 2021 to 2025 count may run low because of a dip in PubMed's indexing, explained under the year chart.

206 animal research papers from 2021 to 2025 mentioned the test
13% fewer papers than in 2011 to 2015
41st of the 90 tests by papers from 2021 to 2025
62% of these papers used mice and 37% used rats

Papers by year

Animal research papers that mention the hole-board, by year, 2001 to 2026

The 2026 bar counts papers added to PubMed by November 8, 2026.

  • Papers in a full year
  • 2026 so far
Show the counts for each year
Papers by year
YearPapers
200127
200231
200323
200434
200529
200646
200738
200843
200945
201042
201137
201245
201358
201442
201554
201643
201737
201831
201943
202044
202145
202243
202344
202433
202541
2026 (part year)43

Papers that mention the hole-board fell from 45 in 2021 to 33 in 2024, then rose to 41 in 2025. Papers that PubMed indexed under the MeSH heading Animals also fell and rose, from 200,221 in 2021 to 156,447 in 2023 and 235,479 in 2025. We take each paper's species from PubMed's indexing whenever it names one, so part of this dip may come from the indexing rather than from fewer studies.

Papers that mention the hole-board in mice and in rats, by year, 2001 to 2025

  • Mouse
  • Rat
Show the counts for each year and species
Papers by year, mice and rats
YearMouseRat
20011614
20021717
20031512
20041913
20051515
20062621
20072513
20082917
20092323
20102415
20112318
20122815
20133618
20142717
20153613
20162813
20171917
2018209
20192713
20203012
20213315
20222615
20232414
20241715
20252717

Which species the papers used

Each bar is a share of the 206 papers from 2021 to 2025. A paper can use more than one species, so the shares can add to more than 100%.

Species

Mouse
127 papers 62%
Rat
76 papers 37%
Other animals
11 papers 5%

โ€œOther animalsโ€ counts papers that use none of the other species in this chart.

Strains and genetic lines

Strain names come from the MeSH terms PubMed adds when it indexes a paper. PubMed has indexed 155 of the 206 papers, so each bar is a share of those 155.

Wistar rats
27 papers 17%
C57BL mice
15 papers 10%
Sprague-Dawley rats
10 papers 6%
BALB/c mice
5 papers 3%
Knockout mice
5 papers 3%
ICR mice
4 papers 3%
Long-Evans rats
3 papers 2%
Other inbred mice
2 papers 1%

A paper indexed under two of these headings, such as knockout mice and a strain, counts under both.

Disease models these papers study

Each bar counts the papers from 2021 to 2025 that mention the hole-board and study that disease model, with its share of the 206 papers. The model comes from a paper's MeSH terms. For a paper PubMed has not indexed, it comes from PubTator 3, NCBI's text-mining service, when that service finds the disease in the title or abstract. A paper can count under more than one model.

Papers from 2021 to 2025 by disease model

83 papers 40%
29 papers 14%
7 papers 3%
6 papers 3%

Tests mentioned alongside the hole-board

Each bar counts the papers from 2021 to 2025 that mention both tests, with its share of the 206 papers that mention the hole-board.

Papers from 2021 to 2025 that mention both tests

99 papers 48%
55 papers 27%
51 papers 25%
32 papers 16%
14 papers 7%
14 papers 7%

The most cited papers from 2021 to 2025

These papers from 2021 to 2025 mention the hole-board and have the most citations, as counted by NIH's iCite on November 5, 2026.

  1. Citrus limon L. (lemon) seed extract shows neuro-modulatory activity in an in vivo thiopental-sodium sleep model by reducing the sleep onset and enhancing the sleep duration.

    J Integr Neurosci, 2022. 61 citations.

  2. Pharmacological insights on the antidepressant, anxiolytic and aphrodisiac potentials of Aglaonema hookerianum Schott.

    J Ethnopharmacol, 2021. 57 citations.

  3. In Vivo Neuropharmacological Effects of Neophytadiene.

    Molecules, 2023. 47 citations.

  4. Neuropharmacological and Antidiabetic Potential of Lannea coromandelica (Houtt.) Merr. Leaves Extract: An Experimental Analysis.

    Evid Based Complement Alternat Med, 2022. 46 citations.

  5. Anxiolytic-like Effects by trans-Ferulic Acid Possibly Occur through GABAergic Interaction Pathways.

    Pharmaceuticals (Basel), 2023. 36 citations.

How we counted

A count is the number of animal research papers whose title or abstract mentions one of the test's search terms. It is not a count of experiments, labs or animals.

A paper that mentions the hole-board only in its methods is missed, so the count runs low. The count includes 3 reviews. For 52 of the 206 papers, PubMed's indexing gave no species, so the species came from PubTator 3 finding one in the title or abstract.

The test's search terms are in the test list download. The full method, with each source and its terms of use, is on our main page, Behavioral tests in published research.

More activity and exploration tests

These activity and exploration tests also have a page, with their papers from 2021 to 2025. Each test with 30 or more papers gets one.

How to cite

APA

ConductScience. (2026, November 10). Hole-board in published research [Data set]. https://conductscience.com/data/behavioral-tests/hole-board

BibTeX

@misc{conductscience_hole_board_2026,
  author = {{ConductScience}},
  title = {Hole-board in published research},
  year = {2026},
  month = nov,
  url = {https://conductscience.com/data/behavioral-tests/hole-board},
  note = {Data set, released November 10, 2026},
}