Description
Mouse |
Length: 40cm |
Width: 40cm |
Height: 35cm |
Diameter Holes: 3cm |
16; 9; 4 floor Hole Board included in order |
16 Nose poke detection cups included in your order |
Clear wall set is included in your order. Black and white wall sets are optional |
Rat |
Length: 60cm |
Width: 60cm |
Height: 45cm |
Diameter Holes: 5cm |
16; 9; 4 floor Hole Board included in order |
16 Nose poke detection cups included in your order |
Clear wall set is included in your order. Black and white wall sets are optional |
Take advantage of Neuralynx, Ethovision Integration, SMS and Email integration with the Conductor Science Software. No I/O Boxes Required
Introduction
This apparatus is applicable in several research areas, including exploratory and anxiety-related behaviors in pharmacological studies (Gupta et al., 2015; Pandey et al., 2016), neurological development and conditions (Segabinazi et al., 2020; Haagensen et al., 2013; Havas et al., 2016), as well as psychology and psychiatric research (Verbitsky et al., 2020).
References
- Christopher L. Kliethermes, John C. Crabbe. Pharmacological and genetic influences on hole-board behaviors in mice (2006). Pharmacology Biochemistry and Behavior.85 (1): 57-65.
- Boissier JR, Simon P. Action de la caféine sur la motilité spontanée de la souris [Action of caffeine on the spontaneous motility of the mouse]. Arch Int Pharmacodyn Ther. 1965 Nov;158(1):212-21. French.
- Brown, Gillian R; Nemes, C (2008). The exploratory behavior of rats in the hole-board apparatus: Is head-dipping a valid measure of neophilia?Behavioral Processes.
- File SE, Wardill AG. Validity of head-dipping as a measure of exploration in a modified hole-board (1975). Psychopharmacologia. 44(1):53-9
- Gupta D, Radhakrishnan M, Thangaraj D, Kurhe Y. Pharmacological evaluation of novel 5-HT3 receptor antagonist, QCM-13 (N-cyclohexyl-3-methoxyquinoxalin-2-carboxamide) as an anti-anxiety agent in behavioral test battery (2015). J Pharm Bioallied Sci.7(2):103-108.
- Greenberg R. The role of neophobia and neophilia in the development of innovative behavior of birds (2003). In: Reader S.M., Laland K.N., editors. Animal Innovation. Cambridge University Press; Cambridge, pp. 175–196.
- Haagensen AM, Klein AB, Ettrup A, Matthews LR, Sørensen DB. Cognitive performance of Göttingen minipigs is affected by diet in a spatial hole-board discrimination test (2013). PLoS One. 8(11):e79429.
- Havas D, Hutter-Paier B, Ubhi K, et al. A longitudinal study of behavioral deficits in an AβPP transgenic mouse model of Alzheimer’s disease (2016). J Alzheimers Dis ;25(2):231-243. doi:10.3233/JAD-2011-101866
- Pandey DK, Devadoss T, Modak N, Mahesh R. Antidepressant & anxiolytic activities of N-(pyridin-3-yl) quinoxalin-2-carboxamide: A novel serotonin type 3 receptor antagonist in behavioral animal models (2016). Indian J Med Res. 144(4):614-621.
- Segabinazi, E et al. “Comparative overview of the effects of aerobic and resistance exercise on anxiety-like behavior, cognitive flexibility, and hippocampal synaptic plasticity parameters in healthy rats.”(2020). Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas vol. 53,11 e9816,
- Verbitsky, A., Dopfel, D. & Zhang, N. Rodent models of post-traumatic stress disorder: behavioral assessment (2020). Transl Psychiatry 10, 132.
- Wernecke, K. E., & Fendt, M.The olfactory hole-board test in rats: a new paradigm to study aversion and preferences to odors (2015). Frontiers in behavioral neuroscience, 9, 223.