ConductScience Syringe Filters 0.45um, PES, Sterile (Pack of 10)
$52.00 per unit | 10 units per pack Bulk pricing: Pack of 10 at $520.00 ($52.00 per unit)
| Automation Level | manual |
0.45 μm PES (polyethersulfone) syringe filters provide reliable sterile filtration for small-volume sample preparation in laboratory environments. These 33mm diameter filters utilize polyethersulfone membrane technology to remove particles and contaminants from aqueous and organic solutions, with a pore size optimized for pre-filtration applications and particulate removal.
The sterile construction enables use in aseptic workflows, making these filters suitable for cell culture media preparation, buffer sterilization, and sample clarification where microbial contamination control is critical. The polyethersulfone membrane offers low protein binding characteristics and broad chemical compatibility with both aqueous and organic solvents.
How It Works
Syringe filtration operates through size exclusion filtration, where the polyethersulfone membrane acts as a physical barrier with precisely controlled pore structure. The 0.45 μm pore size retains particles, bacteria, and other contaminants larger than the pore diameter while allowing smaller molecules and ions to pass through into the filtrate.
The polyethersulfone membrane material provides hydrophilic surface properties that minimize protein adsorption and enable efficient flow rates with aqueous solutions. The membrane structure consists of asymmetric pores that increase in size from the upstream surface to the downstream surface, providing depth filtration that maximizes dirt-holding capacity and extends filter life.
During filtration, applied pressure forces the sample through the membrane matrix, with contaminants being retained on the upstream surface and within the pore structure. The sterile construction ensures that no additional microbial contamination is introduced during the filtration process.
Features & Benefits
Automation Level
- manual
Research Domain
- Analytical Chemistry
- Cell Biology
- Environmental Monitoring
- Food Science
- Microbiology
- Pharmaceutical QC
Weight
- 0.22 kg
Dimensions
- L: 8.3 mm
- W: 6.9 mm
- H: 5.5 mm
Comparison Guide
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Membrane Material | Polyethersulfone (PES) | Entry-level filters often use nylon or mixed cellulose esters | PES provides superior chemical compatibility and lower protein binding for demanding applications |
| Pore Size | 0.45 μm | Standard filtration products typically offer 0.22 μm or 0.8 μm options | 0.45 μm balances particle retention with flow rate for pre-filtration applications |
| Filter Diameter | 33mm | Smaller diameter filters offer 13-25mm membrane area | Larger membrane area provides higher flow rates and greater dirt-holding capacity |
| Sterility Assurance | Sterile construction | Non-sterile filters require separate sterilization steps | Ready-to-use sterile design eliminates contamination risk and preparation time |
These PES syringe filters combine 0.45 μm pore size with 33mm diameter membrane area in sterile construction, providing reliable particle removal for laboratory sample preparation workflows.
Practical Tips
Pre-filter heavily contaminated samples through larger pore size filters to prevent rapid clogging of the 0.45 μm membrane.
Why: Extends filter life and maintains consistent flow rates throughout filtration process.
Apply steady, moderate pressure rather than rapid, high-pressure strokes when operating the syringe.
Why: Prevents membrane damage and ensures consistent pore structure integrity.
Always filter biological samples in appropriately contained environment and dispose of used filters as biohazardous waste.
Why: Prevents exposure to concentrated microorganisms retained on the filter membrane.
Discard the first few drops of filtrate when processing samples for analytical testing.
Why: Eliminates potential contamination from handling and ensures representative sample collection.
If filtration rate decreases significantly during processing, stop and replace filter rather than applying excessive pressure.
Why: High pressure can force contaminants through compromised membrane, defeating the filtration purpose.
Use each filter only once and never attempt to clean or reuse syringe filters.
Why: Single-use design ensures sterility and prevents cross-contamination between samples.
Setup Guide
What’s in the Box
- 100 sterile syringe filters (0.45 μm PES, 33mm)
- Individual sterile packaging (typical)
- Product certificate of analysis (typical)
Warranty
ConductScience provides standard manufacturer warranty covering defects in materials and construction. Technical support available for filtration application guidance and troubleshooting.
Compliance
What is the maximum pressure rating for these filters?
Consult product datasheet for specific pressure specifications. Typical PES syringe filters operate effectively at moderate pressures applied manually through syringe operation.
Are these filters compatible with organic solvents?
Polyethersulfone membranes generally show good compatibility with many organic solvents, but specific chemical compatibility should be verified against the manufacturer's compatibility chart for your specific solvent system.
How do I prevent membrane damage during filtration?
Apply steady, moderate pressure rather than rapid, high pressure. If significant resistance develops, stop filtration as membrane may be clogged or sample may require pre-filtration with larger pore size.
What is the protein binding capacity of PES membranes?
PES membranes are specifically chosen for low protein binding characteristics compared to other membrane materials, though exact binding values depend on specific proteins and solution conditions.
Can these filters be used for virus removal?
0.45 μm pore size removes bacteria and larger microorganisms but is not suitable for virus retention, which typically requires 0.1 μm or smaller pore sizes.
How should these filters be stored?
Store in original sterile packaging in clean, dry environment at room temperature, away from direct sunlight and temperature extremes.
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