Rotary Microtome with 16 Degree Clamp
Precision semi-automated microtome with adjustable angle specimen clamp featuring 16° horizontal and vertical adjustment plus 360° rotation for consistent tissue sectioning in histological applications. Available model: RD-485 PRO.
The Semi-auto Microtome (RF-0012) is a precision sectioning instrument designed for preparing thin tissue specimens for histological examination. This microtome features an adjustable angle specimen clamp that provides horizontal and vertical adjustment capabilities of 16°, along with 360° rotation functionality for optimal sample positioning during sectioning procedures.
The instrument enables researchers to produce consistent, high-quality tissue sections for microscopic analysis across various research applications. The semi-automated operation combines manual control with mechanical precision, allowing operators to maintain sectioning consistency while retaining flexibility for different specimen types and sectioning protocols.
How It Works
The semi-auto microtome operates through controlled mechanical advancement of the specimen block against a sharp microtome knife. The specimen holder advances the tissue block by precise increments, typically ranging from 1-100 micrometers, while the knife remains stationary. Each forward stroke of the handwheel advances the specimen by the preset thickness, while the return stroke clears the knife edge for the next section.
The adjustable angle specimen clamp system allows for optimal specimen orientation relative to the cutting plane. The 16° horizontal and vertical adjustment range, combined with 360° rotational capability, enables precise alignment of tissue structures with the sectioning plane. This adjustability is critical for achieving consistent section quality across different tissue types and orientations, particularly when sectioning specimens with complex three-dimensional structures or when specific anatomical planes are required for analysis.
Features & Benefits
Model
- RD-485 PRO
Weight
- 36.71 kg
Dimensions
- L: 45.0 mm
- W: 35.0 mm
- H: 35.0 mm
Comparison Guide
| Feature | This Product | Typical Alternative | Advantage |
|---|---|---|---|
| Specimen Angle Adjustment | 16° horizontal and vertical adjustment with 360° rotation | Basic models often provide limited or no angle adjustment capabilities | Enables optimal tissue orientation for improved section quality and reduced artifacts across diverse specimen types |
| Operation Mode | Semi-automated advancement with manual control | Entry-level units typically offer only manual operation | Reduces operator fatigue during extended sectioning sessions while maintaining precise control over cutting parameters |
| Positioning Flexibility | Full 360° rotational capability combined with dual-axis angle adjustment | Standard models usually provide fixed positioning or single-axis adjustment | Allows comprehensive specimen reorientation without remounting, facilitating multi-plane sectioning from single blocks |
| Construction Quality | Robust mechanical design with precision adjustment mechanisms | Budget models may have simplified adjustment systems | Maintains sectioning accuracy and adjustment precision over extended laboratory use |
This semi-auto microtome offers advanced specimen positioning capabilities with comprehensive angle and rotational adjustment, combined with semi-automated operation for improved efficiency and consistency in histological specimen preparation.
Practical Tips
Verify section thickness accuracy weekly using calibration standards and adjust the micrometer mechanism as needed.
Why: Maintains sectioning precision and ensures reproducible specimen thickness for quantitative analyses.
Lubricate the angle adjustment mechanisms monthly and inspect for wear or binding in the rotational components.
Why: Prevents mechanical failure and ensures smooth operation of the positioning system over time.
Use the angle adjustment to align fibrous tissues parallel to the knife edge for reduced compression artifacts.
Why: Optimizes section quality by minimizing mechanical distortion during cutting of anisotropic specimens.
If sections appear compressed or torn, adjust the specimen angle slightly and verify knife sharpness.
Why: Poor section quality often results from suboptimal cutting angle or blade condition rather than mechanical issues.
Document specimen orientation and angle settings for each sectioning session to ensure reproducible results.
Why: Enables consistent sectioning parameters across multiple experiments and facilitates method validation.
Always engage safety mechanisms before adjusting specimen position and use proper blade handling procedures.
Why: Prevents accidental blade contact during specimen manipulation and reduces risk of injury.
Allow specimens to equilibrate to room temperature before sectioning to prevent thermal expansion artifacts.
Why: Temperature variations can cause dimensional changes that affect section thickness uniformity and quality.
Setup Guide
What’s in the Box
- Semi-auto microtome main unit
- Adjustable specimen clamp assembly
- Knife holder system (typical)
- Section thickness adjustment controls
- User manual and operation guide
- Calibration tools (typical)
- Safety accessories (typical)
Warranty
ConductScience provides a standard one-year manufacturer warranty covering defects in materials and workmanship, with technical support available for setup, calibration, and troubleshooting assistance.
Compliance
What section thickness range can this microtome achieve?
The specific thickness range specifications are detailed in the product datasheet. Semi-automatic microtomes typically offer section thicknesses from 1-100 micrometers with precise increment control.
How does the 16° angle adjustment benefit different tissue types?
The adjustable angle capability allows optimization of the cutting plane relative to tissue fiber orientation, reducing compression artifacts in fibrous tissues and enabling better section quality for anisotropic specimens.
Is this microtome compatible with both paraffin and frozen sections?
While designed primarily for paraffin-embedded specimens, compatibility with frozen sectioning depends on specific knife selection and temperature considerations. Consult product specifications for recommended applications.
What maintenance is required for the adjustment mechanisms?
Regular lubrication of the adjustment mechanisms and periodic calibration verification are essential. The 360° rotation system requires particular attention to prevent binding and ensure smooth operation.
How precise is the specimen positioning system?
The positioning system provides 16° adjustment range in both horizontal and vertical planes with mechanical precision appropriate for histological applications. Specific angular accuracy tolerances are provided in the technical documentation.
Can this microtome handle large specimen blocks?
The universal specimen compatibility is designed to accommodate various block sizes, though maximum dimensions and weight limits are specified in the product datasheet.
Have a question about this product?
